Genabelle PDRN Vita Toning Ampoule Review

Genabelle PDRN Vita Toning Ampoule
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does Genabelle PDRN Vita Toning Ampoule Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Genabelle PDRN Vita Toning Ampoule has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Genabelle PDRN Vita Toning Ampoule is effective in minimizing wrinkles.
  • Antioxidant protection.

Key Benefits of Genabelle PDRN Vita Toning Ampoule

 
These are the key benefits you can expect from using Genabelle PDRN Vita Toning Ampoule:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Genabelle PDRN Vita Toning Ampoule is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%), Niacinamide (est. ≈4.0%) and Polyglycerin-3 (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, Genabelle PDRN Vita Toning Ampoule has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈4.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Genabelle PDRN Vita Toning Ampoule also contains some ingredients often marketed as effective in reducing wrinkles, specifically Adenosine, Sodium Ascorbyl Phosphate, Tripeptide-1, and Acetyl Hexapeptide-8. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Genabelle PDRN Vita Toning Ampoule is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Genabelle PDRN Vita Toning Ampoule

 
CreamScan AI identified a few things to consider before adding Genabelle PDRN Vita Toning Ampoule to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Genabelle PDRN Vita Toning Ampoule as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Genabelle PDRN Vita Toning Ampoule

 
Here’s an overview of the pros and cons of Genabelle PDRN Vita Toning Ampoule to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Humectant-rich moisturizing ideal for oily skin
  • Lightweight texture
  • A humectant moisturizing boost for any skincare routine
  • Delivers signficant anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage such as UV radiation and pollution

Cons: 

  • Needs occlusives to seal in humectants if used as a standalone moisturizer

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Niacinamide
Function:
Origin:
Polyglycerin-3
Function:
Origin:
Methylpropanediol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Glycereth-26
Function:
Origin:
Glycerin
Function:
Origin:
Mannitol
Function:
Origin:
Sodium DNA
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Microcrystalline Cellulose
Function:
Origin:
Ammonium Acryloyldimethyltaurate/VP Copolymer
Function:
Origin:
Polyacrylate Crosspolymer-6
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Arginine
Function:
Origin:
Zea Mays (Corn) Starch
Function:
Origin:
Milt Extract
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Mica
Function:
Origin:
Allantoin
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Adenosine
Function:
Origin:
Fragrance
Function:
Origin:
Biosaccharide Gum-1
Function:
Origin:
Iron Oxides (CI 77492)
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Tranexamic Acid
Function:
Origin:
Calcium Pantothenate
Function:
Origin:
Maltodextrin
Function:
Origin:
Sodium Starch Octenylsuccinate
Function:
Origin:
Sodium Ascorbyl Phosphate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Pyridoxine HCl
Function:
Origin:
Hydrolyzed Hyaluronic Acid
Function:
Origin:
Hydrolyzed Sodium DNA
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Sodium Acetylated Hyaluronate
Function:
Origin:
Tripeptide-1
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:

Ratings

All humectants
20.9
6
4
3
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 20.9 10
10.0
6
4
3
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
3
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 20.9 10
10
All humectants
20.9
6
4
3
2
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 4 6
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
4
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Sodium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
4
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.8 3 Rich in antioxidants
All antioxidants
5.8
Niacinamide
4
Mannitol
0.3
Sodium Hyaluronate
0.3
Sodium Ascorbyl Phosphate
0.3
Tocopheryl Acetate
0.3
Hydrolyzed Hyaluronic Acid
0.3
Hyaluronic Acid
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
0.3
0.3
0.3
All soothing 4.9 5 No
All soothing
4.9
4
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Niacinamide
Est. %4
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Polyglycerin-3
Est. %3
Function
Origin
Polyglycerin-3
Methylpropanediol
Est. %2
Function
Origin
MethylpropanediolMethylpropanediol is a unique glycol that contains two primary hydroxyl groups. That makes methylpropanediol a powerful humectant and an excellent solvent.
1,2-Hexanediol
Est. %1.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Glycereth-26
Est. %1.3
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Glycerin
Est. %1
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Mannitol
Est. %0.3
Function
Origin
MannitolA sweet-tasting, sugar-derived, humectant alcohol that can stabilize a skincare formula and offer some antioxidant and soothing properties.
Sodium DNA
Est. %0.3
Function
Origin
Sodium DNA
Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Microcrystalline Cellulose
Est. %0.3
Function
Origin
Microcrystalline CelluloseA plant-based ingredient derived from cellulose. The rough version of microcrystalline cellulose is used in scrubs instead of plastic microbeads and the finer version is used as a thickener and stabilizer and readily absorbs oil and sweat.
Ammonium Acryloyldimethyltaurate/VP Copolymer
Est. %0.3
Function
Origin
Ammonium Acryloyldimethyltaurate/VP CopolymerA polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.
Polyacrylate Crosspolymer-6
Est. %0.3
Function
Origin
Polyacrylate Crosspolymer-6A polymeric ingredient that works best in water-based formulas to create gel textures. It helps to stabilize emulsions and control viscosity.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Zea Mays (Corn) Starch
Est. %0.3
Function
Origin
Zea Mays (Corn) StarchA white, very finely powdered starch extracted from corn. It works as an anti-caking and absorbent ingredient in powdered products, as well as as a thickening agent in liquids. It also helps to create a matte finish after application.
Milt Extract
Est. %0.3
Function
Origin
Milt Extract
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Mica
Est. %0.3
Function
Origin
MicaA mineral powder made up of silicates with several functions (the main one being as a colorant). It has a shimmery appearance, making it highly desirable in certain cosmetic products. Mica also helps the product to apply more smoothly.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Biosaccharide Gum-1
Est. %0.3
Function
Origin
Biosaccharide Gum-1A polysaccharide with humectant moisturizing and soothing properties.
Iron Oxides (CI 77492)
Est. %0.3
Function
Origin
Iron Oxides (CI 77492)Also known as iron (III) oxide, this ingredient is a yellow-colored pigment that can either be derived from minerals or produced synthetically. It adds yellow tones to cosmetic products.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Tranexamic Acid
Est. %0.3
Function
Origin
Tranexamic AcidA synthetic amino acid that is used as an astringent to stop the bleeding from small cuts. It also has proven anti-pigment and redness-reducing effects.
Calcium Pantothenate
Est. %0.3
Function
Origin
Calcium PantothenateA vitamin B5 derivative that reduces static buildup on the skin.
Maltodextrin
Est. %0.3
Function
Origin
MaltodextrinA formula helper manufactured from starch. It has a sweet flavor and is often used in rinse-off products to support their foaming structure. Maltodextrin is also used to stabilize emulsions and to absorb and bind other ingredients in the formula.
Sodium Starch Octenylsuccinate
Est. %0.3
Function
Origin
Sodium Starch Octenylsuccinate
Sodium Ascorbyl Phosphate
Est. %0.3
Function
Origin
Sodium Ascorbyl PhosphateThe most researched derivative of vitamin C. It boosts collagen synthesis, thereby improving skin structure and elasticity. SAP is effective in the treatment of inflamed acne lesions and has a weak but positive effect on pigmentation issues.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Pyridoxine HCl
Est. %0.3
Function
Origin
Pyridoxine HClA B-vitamin that helps regulate sebum production.
Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
Hydrolyzed Hyaluronic AcidA smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Hydrolyzed Sodium DNA
Est. %0.3
Function
Origin
Hydrolyzed Sodium DNA
Hyaluronic Acid
Est. %0.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Sodium Acetylated Hyaluronate
Est. %0.3
Function
Origin
Sodium Acetylated HyaluronateA chemically modified version of hyaluronic acid. It is more stable and less sticky than regular HA, while still providing the same humectant moisturizing properties (according to the manufacturer). There have been no clinical studies to confirm this.
Tripeptide-1
Est. %0.3
Function
Origin
Tripeptide-1

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.

Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.