Epionce Intense Defense Serum Review

Epionce Intense Defense Serum
5.4
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.9 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does Epionce Intense Defense Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Epionce Intense Defense Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.4 out of 10.
✅ Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Epionce Intense Defense Serum is effective in minimizing wrinkles.
✅ Antioxidant protection

  

Key Benefits of Epionce Intense Defense Serum

 
These are the key benefits you can expect from using Epionce Intense Defense Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Epionce Intense Defense Serum is quite moisturizing, with a moisturizing rating of 5.4 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.9 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Propanediol (est. ≈6.0%), Niacinamide (est. ≈4.0%) and Glycerin (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, Epionce Intense Defense Serum has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈4.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Epionce Intense Defense Serum also contains Tetrahexyldecyl Ascorbate, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Tetrahexyldecyl Ascorbate provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Tetrahexyldecyl Ascorbate may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Epionce Intense Defense Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Epionce Intense Defense Serum

 
Here’s an overview of the pros and cons of Epionce Intense Defense Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers signficant anti-wrinkle efficacy thanks to Niacinamide
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Epionce Intense Defense Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Epionce Intense Defense Serum
 is specifically effective in treating wrinkles, containing ingredients with solid, robust evidence of anti-wrinkle efficacy.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

With its high antioxidant content, Epionce Intense Defense Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Propanediol
Function:
Origin:
Niacinamide
Function:
Origin:
Glycerin
Function:
Origin:
Trisiloxane
Function:
Origin:
Tetrahexyldecyl Ascorbate
Function:
Origin:
PEG-7 Glyceryl Cocoate
Function:
Origin:
Oryza Sativa (Rice) Bran Extract
Function:
Origin:
Bidens Pilosa Extract
Function:
Origin:
Bixa Orellana Seed Extract
Function:
Origin:
Butylene Glycol
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Crithmum Maritimum Extract
Function:
Origin:
Cucumis Melo (Melon) Fruit Extract
Function:
Origin:
Disodium EDTA
Function:
Origin:
Elaeis Guineensis (Palm) Oil
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Gossypium Herbaceum (Cotton) Seed Oil
Function:
Origin:
Helianthus Annuus (Sunflower) Extract
Function:
Origin:
Hexylene Glycol
Function:
Origin:
Hydrogenated Vegetable Oil
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Hydroxypropyltrimonium Maltodextrin Crosspolymer
Function:
Origin:
Lentinus Edodes Extract
Function:
Origin:
Linum Usitatissimum (Linseed) Seed Oil
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters
Function:
Origin:
Rosmarinus Officinalis (Rosemary) Leaf Extract
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Tocopherol
Function:
Origin:
Tocopheryl Linoleate/Oleate
Function:
Origin:

Ratings

All humectants
14.5
6
4
3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.8
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 14.5 10
10.0
6
4
3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.8 20
0.9
0.3
0.3
0.3
0.3
0.3
0.3
Moisturizing rating
5.4
Ingredient Est. % Benchmark Humectancy
6
4
3
0.3
0.3
0.3
0.3
0.3
All humectants 14.5 10
10
All humectants
14.5
6
4
3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
0.3
0.3
All occlusives 1.8 20
0.9
All occlusives
1.8
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 4 6
n/a
- 1.5 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
4
Tetrahexyldecyl Ascorbate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
4
1.5
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 7.3 3 Rich in antioxidants
All antioxidants
7.3
Niacinamide
4
Tetrahexyldecyl Ascorbate
1.5
Crithmum Maritimum Extract
0.3
Cucumis Melo (Melon) Fruit Extract
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Sodium Hyaluronate
0.3
Tocopherol
0.3
Tocopheryl Linoleate/Oleate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
0.3
0.3
All soothing 4.6 5 No
All soothing
4.6
4
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Propanediol
Est. %6
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Niacinamide
Est. %4
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Trisiloxane
Est. %2
Function
Origin
Trisiloxane
Tetrahexyldecyl Ascorbate
Est. %1.5
Function
Origin
Tetrahexyldecyl AscorbateA lipid-soluble form of vitamin C that is more stable and less irritating than ascorbic acid. According to a recent clinical study, THDA has all the capabilities of regular vitamin C, including anti-wrinkle and anti-pigment activity.
PEG-7 Glyceryl Cocoate
Est. %1.3
Function
Origin
PEG-7 Glyceryl Cocoate

A clear, pale yellow, oil-like emollient manufactured synthetically from coconut oil and polyethylene glycol. It is also used as an emulsifying agent.

Oryza Sativa (Rice) Bran Extract
Est. %1
Function
Origin
Oryza Sativa (Rice) Bran ExtractAn extract from rice bran, the brown outer part of the rice kernel. It contains emollient fatty acids and antioxidants such as tocopherols (vitamin E) and γ-oryzanol.
Bidens Pilosa Extract
Est. %0.3
Function
Origin
Bidens Pilosa Extract
Bixa Orellana Seed Extract
Est. %0.3
Function
Origin
Bixa Orellana Seed Extract
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Crithmum Maritimum Extract
Est. %0.3
Function
Origin
Crithmum Maritimum ExtractDerived from sea fennel, this extract contains antioxidant flavonoids and organic acids and has a spicy, herbaceous aroma.
Cucumis Melo (Melon) Fruit Extract
Est. %0.3
Function
Origin
Cucumis Melo (Melon) Fruit ExtractObtained from the seeds and peels of the melon fruit, this extract has emollient fatty oil and antioxidant phenolic compounds.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Elaeis Guineensis (Palm) Oil
Est. %0.3
Function
Origin
Elaeis Guineensis (Palm) OilA fatty oil expressed from the pulp of the oil palm fruits. It is mostly composed of occlusive and emollient saturated fatty acids. The unrefined oil has a large amount of antioxidant carotenoids.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Gossypium Herbaceum (Cotton) Seed Oil
Est. %0.3
Function
Origin
Gossypium Herbaceum (Cotton) Seed OilDerived from the seeds of the cotton plant, this emollient and occlusive fatty oil is mainly comprised of linoleic and palmitic acids. It also contains large amounts of phospholipids - key components of all cell membranes.
Helianthus Annuus (Sunflower) Extract
Est. %0.3
Function
Origin
Helianthus Annuus (Sunflower) ExtractAn emollient extract derived from sunflower seeds that is packed with skin-benefiting ingredients such as squalene, phytosterols, phospholipids, amino acids, and antioxidant vitamin E.
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
Hydrogenated Vegetable Oil
Est. %0.3
Function
Origin
Hydrogenated Vegetable OilA solid, butter-like substance that is a highly occlusive moisturizer and emollient. It is a mixture of various plant oils (such as soy, olive, corn, canola, peanut, and many others) which has been refined.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Hydroxypropyltrimonium Maltodextrin Crosspolymer
Est. %0.3
Function
Origin
Hydroxypropyltrimonium Maltodextrin Crosspolymer
Lentinus Edodes Extract
Est. %0.3
Function
Origin
Lentinus Edodes Extract
Linum Usitatissimum (Linseed) Seed Oil
Est. %0.3
Function
Origin
Linum Usitatissimum (Linseed) Seed OilAn emollient and occlusive fatty oil pressed from flax seeds. It is the richest source of linolenic fatty acid (it contains up to 50% of it) among vegetable oils.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters
Est. %0.3
Function
Origin
Raspberry Seed Oil/Tocopheryl Succinate Aminopropanediol Esters
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
Rosmarinus Officinalis (Rosemary) Leaf ExtractA soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Tocopheryl Linoleate/Oleate
Est. %0.3
Function
Origin
Tocopheryl Linoleate/Oleate