Dr. Denese SkinScience Firming Facial Collagen Night Serum Review

Dr. Denese SkinScience Firming Facial Collagen Night Serum
5.0
/ 10
Moisturizing
7.3 Humectancy icon Humectancy
2.6 Occlusivity icon Occlusivity
1.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Dr. Denese SkinScience Firming Facial Collagen Night Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Dr. Denese SkinScience Firming Facial Collagen Night Serum has to offer:
 
  • Moderate moisturizing. It has a moisturizing rating of 5.0 out of 10.
  • Slight anti-wrinkle effect: Dr. Denese SkinScience Firming Facial Collagen Night Serum has an anti-wrinkle rating of 1.5 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Soothing: Dr. Denese SkinScience Firming Facial Collagen Night Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Key Benefits of Dr. Denese SkinScience Firming Facial Collagen Night Serum

 
These are the key benefits you can expect from using Dr. Denese SkinScience Firming Facial Collagen Night Serum:
 

Lightweight Moisturizer Well-Suited for Combination and Oily Skin

According to CreamScan analysis, Dr. Denese SkinScience Firming Facial Collagen Night Serum is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 2.6 out of 10 and a high humectancy of 7.3 out of 10, primarily due to the high content of Propanediol (est. ≈4.0%).

This type of moisturizer is well-suited for people with combination and oily skin who want significant hydration in a relatively lightweight, non-greasy formula. It combines a substantial amount of humectants with a limited amount of occlusive to enhance moisturizing efficacy without feeling too heavy.

This product may also be an option for people with normal skin who prefer fast-absorbing textures, as it balances significant moisturizing potential with a relatively lightweight texture.

A Humectant Enhancement for Any Skincare Routine

But it’s not limited to combination and oily skin - such a humectant enhancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, Dr. Denese SkinScience Firming Facial Collagen Night Serum has a slight anti-wrinkle rating of 1.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Glycolic Acid (est. ≈6.0%), 
 a highly effective ingredient in peelings but with moderate anti-wrinkle efficacy in leave-on skincare products, as supported by a single clinical study. This study, involving 72 participants (Thibault et al.), demonstrated that a lotion with 5% GA reduced the fine wrinkling score by 6% after 34 days of use, compared to a vehicle (the same formulation without GA).
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Dr. Denese SkinScience Firming Facial Collagen Night Serum is rich (> 3%) in antioxidants, specifically Avena Sativa (Oat) Kernel Flour (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin Soothing and Calming Potential

Based on the ingredient list analysis, Dr. Denese SkinScience Firming Facial Collagen Night Serum is rich (> 5%) in soothing ingredients, particularly Avena Sativa (Oat) Kernel Flour (est. ≈2.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Dr. Denese SkinScience Firming Facial Collagen Night Serum

 
Here’s an overview of the pros and cons of Dr. Denese SkinScience Firming Facial Collagen Night Serum to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Well-suited for moisturizing combination and oily skin
  • Also an option for people with normal skin who prefer fast-absorbing textures
  • Lightweight texture
  • A humectant moisturizing enhancement for any skincare routine
  • Provides slight anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage such as UV radiation and pollution
  • Contains a high concentration of soothing ingredients, which may help reduce irritation and soothe the skin

Cons: 

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycolic Acid
Function:
Origin:
Propanediol
Function:
Origin:
Squalane
Function:
Origin:
Avena Sativa (Oat) Kernel Flour
Function:
Origin:
Dimethicone
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Ammonium Acryloyldimethyltaurate/VP Copolymer
Function:
Origin:
Butylene Glycol
Function:
Origin:
Portulaca Oleracea Extract
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Behenyl Alcohol
Function:
Origin:
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Hydrolyzed Sodium Hyaluronate
Function:
Origin:
Soluble Collagen
Function:
Origin:
Vaccinium Myrtillus Fruit/Leaf Extract
Function:
Origin:
Saccharum Officinarum (Sugarcane) Extract
Function:
Origin:
Acer Saccharum (Sugar Maple) Extract
Function:
Origin:
Citrus Aurantium Dulcis (Orange) Fruit Extract
Function:
Origin:
Citrus Limon (Lemon) Leaf Extract
Function:
Origin:
Foeniculum Vulgare (Fennel) Fruit Extract
Function:
Origin:
Humulus Lupulus (Hops) Extract
Function:
Origin:
Melissa Officinalis Leaf Extract
Function:
Origin:
Viscum Album (Mistletoe) Leaf Extract
Function:
Origin:
Chamomilla Recutita (Matricaria) Flower Extract
Function:
Origin:
Achillea Millefolium Extract
Function:
Origin:
Urea
Function:
Origin:
Allantoin
Function:
Origin:
Glycine Soja (Soybean) Sterols
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Polyglyceryl-3 Diisostearate
Function:
Origin:
Hydroxypropyl Bislauramide MEA
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Alcohol
Function:
Origin:
Phytosterols
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
PEG-20 Soy Sterol
Function:
Origin:
Hydroxymethoxyphenyl Decanone
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Panthenol
Function:
Origin:
Disodium EDTA
Function:
Origin:
Xanthan Gum
Function:
Origin:
Sclerotium Gum
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
7.3
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
5.1
3.0
1.5
0.3
0.3
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.3 10
7.3
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 5.1 20
2.6
3.0
1.5
0.3
0.3
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 7.3 10
7.3
All humectants
7.3
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
3
1.5
0.3
0.3
All occlusives 5.1 20
2.6
All occlusives
5.1
3.0
1.5
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 6 1.5
Total
1.5
Glycolic Acid
1.5
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
6
Anti-wrinkle rating
1.5
Ingredient Est. % Benchmark
Rich in Antioxidants
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.9 3 Rich in antioxidants
All antioxidants
5.9
Avena Sativa (Oat) Kernel Flour
2
Portulaca Oleracea Extract
0.3
Sodium Hyaluronate
0.3
Hydrolyzed Sodium Hyaluronate
0.3
Vaccinium Myrtillus Fruit/Leaf Extract
0.3
Saccharum Officinarum (Sugarcane) Extract
0.3
Acer Saccharum (Sugar Maple) Extract
0.3
Citrus Aurantium Dulcis (Orange) Fruit Extract
0.3
Citrus Limon (Lemon) Leaf Extract
0.3
Humulus Lupulus (Hops) Extract
0.3
Melissa Officinalis Leaf Extract
0.3
Chamomilla Recutita (Matricaria) Flower Extract
0.3
Phytosterols
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 5 5 Rich in soothing
All soothing
5
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycolic Acid
Est. %6
Function
Origin
Glycolic Acid

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Propanediol
Est. %4
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Squalane
Est. %3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Avena Sativa (Oat) Kernel Flour
Est. %2
Function
Origin
Avena Sativa (Oat) Kernel FlourA mild abrasive, finely milled oat kernel flour that is also used as a formula helper.
Dimethicone
Est. %1.5
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Sodium Hydroxide
Est. %1.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Ammonium Acryloyldimethyltaurate/VP Copolymer
Est. %1
Function
Origin
Ammonium Acryloyldimethyltaurate/VP CopolymerA polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Portulaca Oleracea Extract
Est. %0.3
Function
Origin
Portulaca Oleracea ExtractDerived from green or common purslane, this moisturizing extract is particularly rich in alpha-linolenic acid, an omega-3 fatty acid, and contains antioxidant glutathione and vitamin E. As a herbal medicine, it is believed to treat headaches and inflammation.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Cetearyl Alcohol
Est. %0.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Behenyl Alcohol
Est. %0.3
Function
Origin
Behenyl AlcoholA fatty alcohol with emollient properties. It is used as a co-emulsifier and thickener and tends to result in a product with a smooth and creamy application texture.
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Est. %0.3
Function
Origin
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Hydrolyzed Sodium Hyaluronate
Est. %0.3
Function
Origin
Hydrolyzed Sodium HyaluronateA very small-molecule version of regular sodium hyaluronate. It is a powerful humectant skin-identical ingredient that absorbs into the skin and offers plumping, smoothing, and anti-wrinkle effects.
Soluble Collagen
Est. %0.3
Function
Origin
Soluble CollagenA protein obtained from farm or marine animals. Collagen molecules are too big to penetrate the skin so when they are applied via a skincare product they sit on top of the skin and act as humectant moisturizers.
Vaccinium Myrtillus Fruit/Leaf Extract
Est. %0.3
Function
Origin
Vaccinium Myrtillus Fruit/Leaf ExtractDerived from the berries and leaves of the bilberry plant, this powerful antioxidant, astringent, and refreshing extract is rich in anthocyanins, flavonoids, and tannins.
Saccharum Officinarum (Sugarcane) Extract
Est. %0.3
Function
Origin
Saccharum Officinarum (Sugarcane) ExtractAn antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Acer Saccharum (Sugar Maple) Extract
Est. %0.3
Function
Origin
Acer Saccharum (Sugar Maple) ExtractAn antioxidant extract from sugar maple bark and sap – the same sweet sap used to make maple syrup. It has a faint vanilla smell and is used in skincare for its exfoliating properties. This is because of the small sugar crystals present in the extract.
Citrus Aurantium Dulcis (Orange) Fruit Extract
Est. %0.3
Function
Origin
Citrus Aurantium Dulcis (Orange) Fruit Extract

An extract from the fruit of the sweet orange. It contains fragrant sweet orange essential oil, high amounts of antioxidant flavonoids (mainly hesperidin), and carotenoids – which give it the orange color.

Citrus Limon (Lemon) Leaf Extract
Est. %0.3
Function
Origin
Citrus Limon (Lemon) Leaf Extract
Foeniculum Vulgare (Fennel) Fruit Extract
Est. %0.3
Function
Origin
Foeniculum Vulgare (Fennel) Fruit ExtractA fragrant extract derived from fennel that contains a warm, spicy essential oil and an emollient fatty oil.
Humulus Lupulus (Hops) Extract
Est. %0.3
Function
Origin
Humulus Lupulus (Hops) ExtractAn extract from hops flowers. Hops have been used traditionally to treat skin inflammation. The extract is rich in antioxidants and has antifungal and antimicrobial activity.
Melissa Officinalis Leaf Extract
Est. %0.3
Function
Origin
Melissa Officinalis Leaf ExtractA fragrant extract derived from lemon balm leaves with antioxidant and antiviral flavonoids and terpenes. It has a lovely, fresh, lemon-like scent.
Viscum Album (Mistletoe) Leaf Extract
Est. %0.3
Function
Origin
Viscum Album (Mistletoe) Leaf Extract
Chamomilla Recutita (Matricaria) Flower Extract
Est. %0.3
Function
Origin
Chamomilla Recutita (Matricaria) Flower ExtractDerived from German chamomile flowers, this extract is especially known for its anti-inflammatory and soothing benefits. It contains two soothing compounds called chamazulene and bisabolol, as well as antioxidant flavonoids.
Achillea Millefolium Extract
Est. %0.3
Function
Origin
Achillea Millefolium ExtractAn extract obtained from the common yarrow. It is full of astringent and anti-inflammatory phytochemicals that help with inflamed skin and wound healing, have soothing and refreshing effects on the skin, and give the product a fresh, green, and spicy scent.
Urea
Est. %0.3
Function
Origin
UreaUrea can be found in urine, skin, and other tissues as a degradation product of proteins. In concentrations below 5%, urea is humectant moisturizing. At concentrations above 10% it is keratolytic, that helps to break away old, flaking, and cracked skin.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Glycine Soja (Soybean) Sterols
Est. %0.3
Function
Origin
Glycine Soja (Soybean) SterolsA mixture of phytosterols isolated from soybean oil. Phytosterols, when used in skincare products, have emollient properties and can make the skin feel softer and smoother.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Polyglyceryl-3 Diisostearate
Est. %0.3
Function
Origin
Polyglyceryl-3 DiisostearateA vegetable-based ingredient that stabilizes mixtures of oil and water.
Hydroxypropyl Bislauramide MEA
Est. %0.3
Function
Origin
Hydroxypropyl Bislauramide MEA
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Stearyl Alcohol
Est. %0.3
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Alcohol
Est. %0.3
Function
Origin
AlcoholAn effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
Phytosterols
Est. %0.3
Function
Origin
PhytosterolsA plant-based version of cholesterol that is used for its emollient properties in skincare. The richest sources of phytosterols are corn, rapeseed, and wheat germ oil.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
PEG-20 Soy Sterol
Est. %0.3
Function
Origin
PEG-20 Soy Sterol
Hydroxymethoxyphenyl Decanone
Est. %0.3
Function
Origin
Hydroxymethoxyphenyl Decanone
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Sclerotium Gum
Est. %0.3
Function
Origin
Sclerotium GumA thickener with a silky, velvety feel that many manufacturers use as an alternative to silicones.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.