Derm Institute Cellular Rejuvenating Tightener

Derm Institute Cellular Rejuvenating Tightener
5.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
2.6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
$$$$

Review

Results you may expect from using Derm Institute Cellular Rejuvenating Tightener:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Derm Institute Cellular Rejuvenating Tightener:

  • Moderate moisturizing. It has a moisturizing rating of 5.2 out of 10.
  • Some anti-wrinkle efficacy: Derm Institute Cellular Rejuvenating Tightener has an anti-wrinkle rating of 2.6 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Soothing: Derm Institute Cellular Rejuvenating Tightener contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Derm Institute Cellular Rejuvenating Tightener has a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.3 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%), Aloe Barbadensis Leaf Juice (est. ≈4.0%) and Butylene Glycol (est. ≈3.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Derm Institute Cellular Rejuvenating Tightener has a slight anti-wrinkle rating of 2.6 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Retinol (est. ≈0.1%),
    the most effective non-prescription ingredient with well-proven efficacy to reduce wrinkles.
  • Ascorbic Acid (est. ≈0.3%),
    or Vitamin C, a popular anti-wrinkle ingredient, yet with average efficacy confirmed by only one study.
Among others, Derm Institute Cellular Rejuvenating Tightener also contains some ingredients marketed as effective in reducing wrinkles, specifically Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, and Melia Azadirachta Leaf Extract. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Derm Institute Cellular Rejuvenating Tightener is rich (> 3%) in antioxidants, specifically Aloe Barbadensis Leaf Juice (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Derm Institute Cellular Rejuvenating Tightener is rich (> 5%) in soothing ingredients, particularly Aloe Barbadensis Leaf Juice (est. ≈4.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
18.4
6
4
3
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 18.4 10
10.0
6
4
3
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient Est. % Benchmark Humectancy
6
4
3
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 18.4 10
10
All humectants
18.4
6
4
3
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.1 2.5
2.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
2.6
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Palmitoyl Tripeptide-5
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Dipeptide Diaminobutyroyl Benzylamide Diacetate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.6
Ingredient Est. % Benchmark
Rich in Antioxidants
4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 7.3 3 Rich in antioxidants
All antioxidants
7.3
Aloe Barbadensis Leaf Juice
4
Ascorbic Acid
0.3
Algae Extract
0.3
Glycine Soja (Soybean) Oil
0.3
Sodium Hyaluronate
0.3
Ananas Sativus (Pineapple) Fruit Extract
0.3
Corallina Officinalis Extract
0.3
Scutellaria Baicalensis Root Extract
0.3
Sodium Sulfite
0.3
Melia Azadirachta Leaf Extract
0.3
Tocopherol
0.3
Colloidal Platinum
0.3
Benchmark
3
Ingredient Est. % Benchmark Rating
4
0.3
0.3
0.3
0.3
All soothing 5.2 5 Rich in soothing
All soothing
5.2
4
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Aloe Barbadensis Leaf Juice
Est. %4
Function
Origin
A gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Butylene Glycol
Est. %3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Pentylene Glycol
Est. %2
Function
Origin
A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.
Pullulan
Est. %1.5
Function
Origin
Description is coming soon
Caprylyl Glycol
Est. %1.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Leuconostoc/Radish Root Ferment Filtrate
Est. %1
Function
Origin
A biotechnological fermentation ingredient that is created by feeding radish root to Leuconostoc kimchii. It allegedly contains organic acids and a mixture of peptides known as bacteriocins – which have antimicrobial activity.
Propylene Glycol
Est. %0.3
Function
Origin
A clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Ethylhexylglycerin
Est. %0.3
Function
Origin
A preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
PEG-40 Hydrogenated Castor Oil
Est. %0.3
Function
Origin
A castor oil-derived ingredient often used to incorporate small amounts of oil (such as a fragrance) into a water-based product. PEG-4 HCO is a gold-standard solubilizer and can be used in low amounts due to its ability to solubilize things so well.
Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Carbomer
Est. %0.3
Function
Origin
A synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Algae Extract
Est. %0.3
Function
Origin
The name describes any extract made from any kind of algae. Algae extracts are moisturizing humectants – the gelatin-like polysaccharides bind and retain water, thereby hydrating the skin. Algae is a rich source of emollient and antioxidant compounds.
Tremella Fuciformis Polysaccharide
Est. %0.3
Function
Origin
Description is coming soon
Cucumis Sativus (Cucumber) Fruit Extract
Est. %0.3
Function
Origin
A soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Palmitoyl Tripeptide-5
Est. %0.3
Function
Origin
A small synthetic peptide that signals the skin to produce more collagen. It has been clinically tested and proven to reduce skin roughness and the appearance of wrinkles.
Potassium Sorbate
Est. %0.3
Function
Origin
A preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Sodium Benzoate
Est. %0.3
Function
Origin
A preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Glycine Soja (Soybean) Oil
Est. %0.3
Function
Origin
An occlusive moisturizing oil expressed from soybeans. It does not leave an oily feeling on the skin due to its low content of saturated fatty acids. Glycine soja oil contains emollient fatty acids and a significant amount of antioxidants.
Sodium Hyaluronate
Est. %0.3
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Bacopa Monnieri Extract
Est. %0.3
Function
Origin
Description is coming soon
Synthetic Fluorphlogopite
Est. %0.3
Function
Origin
Also known as synthetic mica, this ingredient’s best property is its ability to form thin, sheet-like crystals. This gives products (mostly makeup) great slip.
Ananas Sativus (Pineapple) Fruit Extract
Est. %0.3
Function
Origin
An extract derived from pineapple fruits that contains various antioxidants, vitamin C, and bromelain - an enzyme mixture that acts as a mild exfoliant. Bromelain also has some anti-inflammatory activity and may help with the healing of wounds and scars.
Citric Acid
Est. %0.3
Function
Origin
A gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Hydrolyzed Soy Protein
Est. %0.3
Function
Origin
A mixture of proteins obtained from soybeans. It can have many different functions depending on the manufacturer, although it is most commonly used in skincare products as a humectant moisturizing ingredient.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Corallina Officinalis Extract
Est. %0.3
Function
Origin
An extract from red marine alga, Corallina officinalis is used in skincare for its antioxidant properties. It also contains an immense amount of calcium and special, sulfur-containing polysaccharides.
Scutellaria Baicalensis Root Extract
Est. %0.3
Function
Origin
A powerful antioxidant, soothing, and astringent extract derived from the roots of Baikal/Chinese skullcap. It contains various unique flavonoids that are believed to soothe irritated and inflamed skin and protect from UV-induced oxidative damage.
Retinol
Est. %0.1
Function
Origin

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Dipeptide Diaminobutyroyl Benzylamide Diacetate
Est. %0.3
Function
Origin
A synthetically made peptide similar to the proteins in viper venom. Similarly to Botox, it works by inhibiting contractions of mimic muscles, thereby offering a short-term reduction in mimic wrinkles.
Sodium Sulfite
Est. %0.3
Function
Origin
An inorganic salt that defends against oxidation.
Acetyl Tyrosine
Est. %0.3
Function
Origin
Acetyl tyrosine is a derivative of the amino acid tyrosine. It is used as a tanning agent in skincare, helping pigment cells (melanosomes) to produce more dark skin pigment.
Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
An antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Hydroxyethylcellulose
Est. %0.3
Function
Origin
A naturally-derived thickener that can form clear gel textures without the slimy feeling, unlike some other natural gel-formers.
Proline
Est. %0.3
Function
Origin
The best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Adenosine Triphosphate
Est. %0.3
Function
Origin
A cellular energy source that is thought to revitalize skin cells.
Ascorbic Acid
Est. %0.3
Function
Origin

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Hydrolyzed Vegetable Protein
Est. %0.3
Function
Origin
A blanket term used for plant-based proteins that have been processed into smaller chunks. They add to the skincare product's film-forming and water-binding properties.
Tocopherol
Est. %0.3
Function
Origin
Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
PEG-12 Glyceryl Laurate
Est. %0.3
Function
Origin
Description is coming soon
PEG-35 Castor Oil
Est. %0.3
Function
Origin
Description is coming soon
PVP
Est. %0.3
Function
Origin
An excellent film-former used in hairsprays, peel-off masks, and even some self-tanning products. These films are strong and hold onto the skin.
Acacia Senegal Gum
Est. %0.3
Function
Origin
A formula helper, also known as gum arabic, derived from the African Acacia tree. It is used in skincare formulas due to its good adhesive and film-forming properties.
1,2-Hexanediol
Est. %0.3
Function
Origin
A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Propylene Glycol Alginate
Est. %0.3
Function
Origin
Description is coming soon
Acetyl Tetrapeptide-17
Est. %0.3
Function
Origin
Description is coming soon
Colloidal Platinum
Est. %0.3
Function
Origin
Description is coming soon
Biotin
Est. %0.3
Function
Origin
Biotin is an important nutrient that can cause weak hair and nails if deficient. Unfortunately, while biotin supplements have promising studies, topical biotin in creams and serums doesn’t have a large body of evidence to support its use.
Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.