APLB Glutathione Niacinamide Ampoule Serum

APLB Glutathione Niacinamide Ampoule Serum
5.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Results you may expect from using APLB Glutathione Niacinamide Ampoule Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using APLB Glutathione Niacinamide Ampoule Serum:

  • Moderate moisturizing. It has a moisturizing rating of 5.2 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, APLB Glutathione Niacinamide Ampoule Serum is effective in minimizing wrinkles.
  • Soothing: APLB Glutathione Niacinamide Ampoule Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: APLB Glutathione Niacinamide Ampoule Serum has a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.3 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈4.0%), Propanediol (est. ≈3.0%) and Niacinamide (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, APLB Glutathione Niacinamide Ampoule Serum has a high anti-wrinkle rating of 6.0 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈2.0%),
     one of the most effective and well-researched anti-wrinkle ingredients.
  • Asiaticoside (est. ≈0.3%),
     derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy confirmed by one study.
Among others, APLB Glutathione Niacinamide Ampoule Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically Beta-Glucan, Adenosine, Madecassic Acid, and Asiatic Acid. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that APLB Glutathione Niacinamide Ampoule Serum is rich (> 3%) in antioxidants, specifically Houttuynia Cordata Extract (est. ≈29.2%) and Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, APLB Glutathione Niacinamide Ampoule Serum is rich (> 5%) in soothing ingredients, particularly Houttuynia Cordata Extract (est. ≈29.2%) and Niacinamide (est. ≈2.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
45
Water
29.2
Houttuynia Cordata Extract
4
Butylene Glycol
3
Propanediol
2
Niacinamide
1.5
Glycerin
1.3
Diethoxyethyl Succinate
1
Panthenol
0.3
Sodium Hyaluronate
0.3
Allantoin
0.3
Glutathione
0.3
Sodium Polyacryloyldimethyl Taurate
0.3
Glyceryl Acrylate/Acrylic Acid Copolymer
0.3
Nelumbo Nucifera Extract
0.3
Artemisia Capillaris Extract
0.3
Oryza Sativa (Rice) Extract
0.3
Saccharomyces Ferment Filtrate
0.3
Solanum Melongena (Eggplant) Fruit Extract
0.3
Melaleuca Alternifolia (Tea Tree) Leaf Extract
0.3
Hydrolyzed Collagen
0.3
Squalane
0.3
Beta-Glucan
0.3
Dipropylene Glycol
0.3
Vitex Trifolia Fruit Extract
0.3
Adenosine
0.3
Madecassic Acid
0.3
Asiaticoside
0.3
Asiatic Acid
0.3
Caprylic/Capric Triglyceride
0.3
Hydrogenated Lecithin
0.3
Glyceryl Stearate
0.3
Cholesterol
0.3
Styrene/Acrylates Copolymer
0.3
Cellulose Gum
0.3
Xanthan Gum
0.3
Ethylhexylglycerin
0.3
Cellulose
0.3
Glucose
0.3
Fructooligosaccharides
0.3
Citric Acid
0.3
Disodium EDTA
0.3
Hydroxyacetophenone
0.3
1,2-Hexanediol
0.3
Dipotassium Glycyrrhizate
0.3
Sodium Citrate
Est. %
Water
Function:
Origin:
Houttuynia Cordata Extract
Function:
Origin:
Butylene Glycol
Function:
Origin:
Propanediol
Function:
Origin:
Niacinamide
Function:
Origin:
Glycerin
Function:
Origin:
Diethoxyethyl Succinate
Function:
Origin:
Panthenol
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Allantoin
Function:
Origin:
Glutathione
Function:
Origin:
Sodium Polyacryloyldimethyl Taurate
Function:
Origin:
Glyceryl Acrylate/Acrylic Acid Copolymer
Function:
Origin:
Nelumbo Nucifera Extract
Function:
Origin:
Artemisia Capillaris Extract
Function:
Origin:
Oryza Sativa (Rice) Extract
Function:
Origin:
Saccharomyces Ferment Filtrate
Function:
Origin:
Solanum Melongena (Eggplant) Fruit Extract
Function:
Origin:
Melaleuca Alternifolia (Tea Tree) Leaf Extract
Function:
Origin:
Hydrolyzed Collagen
Function:
Origin:
Squalane
Function:
Origin:
Beta-Glucan
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Vitex Trifolia Fruit Extract
Function:
Origin:
Adenosine
Function:
Origin:
Madecassic Acid
Function:
Origin:
Asiaticoside
Function:
Origin:
Asiatic Acid
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Cholesterol
Function:
Origin:
Styrene/Acrylates Copolymer
Function:
Origin:
Cellulose Gum
Function:
Origin:
Xanthan Gum
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Cellulose
Function:
Origin:
Glucose
Function:
Origin:
Fructooligosaccharides
Function:
Origin:
Citric Acid
Function:
Origin:
Disodium EDTA
Function:
Origin:
Hydroxyacetophenone
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Sodium Citrate
Function:
Origin:

Ratings

All humectants
14.5
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 14.5 10
10.0
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Humectancy
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 14.5 10
10
All humectants
14.5
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
3 /10 0.1 0.3 3
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
6
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Madecassic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Asiatic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
29.2
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 33.3 3 Rich in antioxidants
All antioxidants
33.3
Houttuynia Cordata Extract
29.2
Niacinamide
2
Asiaticoside
0.3
Sodium Hyaluronate
0.3
Glutathione
0.3
Nelumbo Nucifera Extract
0.3
Solanum Melongena (Eggplant) Fruit Extract
0.3
Beta-Glucan
0.3
Hydroxyacetophenone
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
29.2
2
1
0.3
0.3
0.3
0.3
All soothing 10 5 Rich in soothing
All soothing
10
29.2
2
1
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %45
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Houttuynia Cordata Extract
Est. %29.2
Function
Origin
Houttuynia Cordata ExtractAn extract from a herbaceous plant fish leaf. It contains various antioxidant and anti-inflammatory compounds. It shows interesting antimicrobial potential due to its unique phytochemical composition.
Butylene Glycol
Est. %4
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Propanediol
Est. %3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Diethoxyethyl Succinate
Est. %1.3
Function
Origin
Diethoxyethyl SuccinateDescription is coming soon
Panthenol
Est. %1
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Sodium Polyacryloyldimethyl Taurate
Est. %0.3
Function
Origin
Sodium Polyacryloyldimethyl TaurateDescription is coming soon
Glyceryl Acrylate/Acrylic Acid Copolymer
Est. %0.3
Function
Origin
Glyceryl Acrylate/Acrylic Acid CopolymerA synthetic humectant moisturizer often paired with glycerin. It also functions as a viscosity-controlling agent that creates gel-like formulas with thicker textures.
Nelumbo Nucifera Extract
Est. %0.3
Function
Origin
Nelumbo Nucifera ExtractDescription is coming soon
Artemisia Capillaris Extract
Est. %0.3
Function
Origin
Artemisia Capillaris ExtractDescription is coming soon
Oryza Sativa (Rice) Extract
Est. %0.3
Function
Origin
Oryza Sativa (Rice) ExtractAn abrasive rice extract rich in various emollient fatty acids, amino acids, and vitamin E.
Saccharomyces Ferment Filtrate
Est. %0.3
Function
Origin
Saccharomyces Ferment FiltrateA yeast mixture that contains humectant moisturizing amino acids, nucleic acids (building blocks of DNA), peptides, various minerals, and vitamins.
Solanum Melongena (Eggplant) Fruit Extract
Est. %0.3
Function
Origin
Solanum Melongena (Eggplant) Fruit ExtractAn under-researched extract obtained from the eggplant fruit. Eggplant contains plant pigments called anthocyanins and phenolic compounds, such as chlorogenic acid, which are excellent antioxidants.
Melaleuca Alternifolia (Tea Tree) Leaf Extract
Est. %0.3
Function
Origin
Melaleuca Alternifolia (Tea Tree) Leaf ExtractA fragrant tea tree leaf extract with antimicrobial, antiseptic, and antioxidant flavonoids and terpenoids.
Hydrolyzed Collagen
Est. %0.3
Function
Origin
Hydrolyzed Collagen

A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.

Squalane
Est. %0.3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Dipropylene Glycol
Est. %0.3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Vitex Trifolia Fruit Extract
Est. %0.3
Function
Origin
Vitex Trifolia Fruit ExtractDescription is coming soon
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Madecassic Acid
Est. %0.3
Function
Origin
Madecassic AcidAn isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns.
Asiaticoside
Est. %0.3
Function
Origin
Asiaticoside

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Asiatic Acid
Est. %0.3
Function
Origin
Asiatic AcidA compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Styrene/Acrylates Copolymer
Est. %0.3
Function
Origin
Styrene/Acrylates CopolymerDescription is coming soon
Cellulose Gum
Est. %0.3
Function
Origin
Cellulose GumA polymer that is derived from its namesake, cellulose, which is plant-based. It has many formula-helper benefits, including thickening and product stabilization.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Cellulose
Est. %0.3
Function
Origin
CelluloseA natural ingredient that can create water-based gels, absorb oils, and exfoliate the skin. One of the main functions of cellulose is as a bulking and viscosity controlling agent. Cellulose can also modify the slip aesthetics and act as an opacifying agent.
Glucose
Est. %0.3
Function
Origin
GlucoseA simple sugar that is also one of two components of sucrose, or table sugar. It is used as a humectant in skincare products. Glucose is also used to flavor lip care cosmetics because of its mildly sweet taste.
Fructooligosaccharides
Est. %0.3
Function
Origin
FructooligosaccharidesA derivative a fructose that moisturizes skin by drawing water to the surface of the skin.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Hydroxyacetophenone
Est. %0.3
Function
Origin
HydroxyacetophenoneAn antioxidant compound that can be found in many plants, although it is manufactured synthetically for skincare purposes. It can boost the preservative action of other conservants.
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.