Acwell Phyto Active Balancing Ampoule Review

Acwell Phyto Active Balancing Ampoule
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does Acwell Phyto Active Balancing Ampoule Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Acwell Phyto Active Balancing Ampoule has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Modest anti-wrinkle efficacy: Acwell Phyto Active Balancing Ampoule has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Key Benefits of Acwell Phyto Active Balancing Ampoule

 
These are the key benefits you can expect from using Acwell Phyto Active Balancing Ampoule:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Acwell Phyto Active Balancing Ampoule is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%), Propanediol (est. ≈4.0%) and Betaine (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Acwell Phyto Active Balancing Ampoule has a modest level of anti-wrinkle efficacy, rated 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈2.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Acwell Phyto Active Balancing Ampoule also contains some ingredients marketed often as effective in reducing wrinkles, specifically Centella Asiatica Extract, Adenosine, and Beta-Glucan. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Acwell Phyto Active Balancing Ampoule is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Acwell Phyto Active Balancing Ampoule

 
CreamScan AI identified a few things to consider before adding Acwell Phyto Active Balancing Ampoule to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Acwell Phyto Active Balancing Ampoule as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Acwell Phyto Active Balancing Ampoule

 
Here’s an overview of the pros and cons of Acwell Phyto Active Balancing Ampoule to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Offers modest anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage

Cons: 

  • Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants

Ingredients

Est. % Ingredient Origin Functions
65
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Propanediol
Function:
Origin:
Betaine
Function:
Origin:
Niacinamide
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Dicaprylyl Ether
Function:
Origin:
Dicaprylyl Carbonate
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Laminaria Japonica Extract
Function:
Origin:
Eclipta Prostrata Leaf Extract
Function:
Origin:
Glycyrrhiza Uralensis (Licorice) Root Extract
Function:
Origin:
Sciadopitys Verticillata Root Extract
Function:
Origin:
Salvia Miltiorrhiza Root Extract
Function:
Origin:
Dioscorea Japonica Root Extract
Function:
Origin:
Theobroma Cacao (Cocoa) Seed Extract
Function:
Origin:
Piper Methysticum Leaf/Root/Stem Extract
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Panax Ginseng Berry Extract
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Methylpropanediol
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Xanthan Gum
Function:
Origin:
Tromethamine
Function:
Origin:
Adenosine
Function:
Origin:
Fructooligosaccharides
Function:
Origin:
Beta-Glucan
Function:
Origin:
Dextrin
Function:
Origin:
Polyquaternium-51
Function:
Origin:
Hydrolyzed Hyaluronic Acid
Function:
Origin:
Saccharide Isomerate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycosphingolipids
Function:
Origin:
Phospholipids
Function:
Origin:
Glycine
Function:
Origin:
Glutamic Acid
Function:
Origin:
Leucine
Function:
Origin:
Serine
Function:
Origin:
Aspartic Acid
Function:
Origin:
Lysine
Function:
Origin:
Methionine
Function:
Origin:
Valine
Function:
Origin:
Sodium Citrate
Function:
Origin:
Cysteine
Function:
Origin:
Citric Acid
Function:
Origin:
Isoleucine
Function:
Origin:
Alanine
Function:
Origin:
Arginine
Function:
Origin:
Cholesterol
Function:
Origin:
Tyrosine
Function:
Origin:
Threonine
Function:
Origin:
Phenylalanine
Function:
Origin:
Proline
Function:
Origin:
Histidine
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:

Ratings

All humectants
21.0
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 21.0 10
10.0
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 21.0 10
10
All humectants
21.0
6
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
3
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 3.8 3 Rich in antioxidants
All antioxidants
3.8
Niacinamide
2
Glycyrrhiza Uralensis (Licorice) Root Extract
0.3
Theobroma Cacao (Cocoa) Seed Extract
0.3
Centella Asiatica Extract
0.3
Beta-Glucan
0.3
Hydrolyzed Hyaluronic Acid
0.3
Cysteine
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
All soothing 2.9 5 No
All soothing
2.9
2
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Propanediol
Est. %4
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Betaine
Est. %3
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

1,2-Hexanediol
Est. %1.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Dicaprylyl Ether
Est. %1.3
Function
Origin
Dicaprylyl EtherA fast-spreading and very lightweight emollient. It is used to reduce the tack and oiliness of oil-based formulas and gives the skin a dry, silky after-feel. It is also a great solvent.
Dicaprylyl Carbonate
Est. %1
Function
Origin
Dicaprylyl CarbonateA very fast-spreading emollient that gives a product an incredibly lightweight feel. Dicaprylyl carbonate works well as a solvent for suspending insoluble solids such as mineral sunscreens or iron oxide pigments.
Pentylene Glycol
Est. %0.3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Laminaria Japonica Extract
Est. %0.3
Function
Origin
Laminaria Japonica ExtractDerived from a species of edible seaweed, this extract contains many different moisturizing and gel-forming polysaccharides.
Eclipta Prostrata Leaf Extract
Est. %0.3
Function
Origin
Eclipta Prostrata Leaf Extract
Glycyrrhiza Uralensis (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Uralensis (Licorice) Root ExtractA soothing and anti-pigment extract derived from a species of licorice with glycyrrhizin as the main active ingredient.
Sciadopitys Verticillata Root Extract
Est. %0.3
Function
Origin
Sciadopitys Verticillata Root Extract
Salvia Miltiorrhiza Root Extract
Est. %0.3
Function
Origin
Salvia Miltiorrhiza Root Extract
Dioscorea Japonica Root Extract
Est. %0.3
Function
Origin
Dioscorea Japonica Root Extract
Theobroma Cacao (Cocoa) Seed Extract
Est. %0.3
Function
Origin
Theobroma Cacao (Cocoa) Seed ExtractA cocoa beans extract that contains caffeine and astringent and antioxidant flavonols and tannins.
Piper Methysticum Leaf/Root/Stem Extract
Est. %0.3
Function
Origin
Piper Methysticum Leaf/Root/Stem Extract
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Panax Ginseng Berry Extract
Est. %0.3
Function
Origin
Panax Ginseng Berry Extract
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Methylpropanediol
Est. %0.3
Function
Origin
MethylpropanediolMethylpropanediol is a unique glycol that contains two primary hydroxyl groups. That makes methylpropanediol a powerful humectant and an excellent solvent.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Fructooligosaccharides
Est. %0.3
Function
Origin
FructooligosaccharidesA derivative a fructose that moisturizes skin by drawing water to the surface of the skin.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Dextrin
Est. %0.3
Function
Origin
DextrinA partially hydrolyzed potato starch, most commonly used as a viscosity controlling and binding agent. When dispersed into water, it can create textures ranging from a thick paste to a soft gel.
Polyquaternium-51
Est. %0.3
Function
Origin
Polyquaternium-51A biocompatible phospholipid copolymer that is designed to mimic the lipid-based cell membrane found in human skin. Its main function is as a humectant moisturizer.
Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
Hydrolyzed Hyaluronic AcidA smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Saccharide Isomerate
Est. %0.3
Function
Origin
Saccharide IsomerateA naturally-derived humectant that provides moisturization at low levels and is less sticky than other humectants like glycerin.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycosphingolipids
Est. %0.3
Function
Origin
GlycosphingolipidsGlycosphingolipids are body-natural compounds related to ceramides. Structurally, they are ceramide-like lipids with one or multiple sugar residues attached. They are used as emollients in skincare products, giving the skin a soft and smooth after-feel.
Phospholipids
Est. %0.3
Function
Origin
PhospholipidsA large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Leucine
Est. %0.3
Function
Origin
LeucineA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to increase water content on the skin’s surface and is often used in conjunction with anti-pigmentation products.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Aspartic Acid
Est. %0.3
Function
Origin
Aspartic AcidA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to retain water on the skin’s surface and is slightly acidic, thereby helping to balance the pH of a skincare product.
Lysine
Est. %0.3
Function
Origin
LysineA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It is slightly alkaline and helps to balance the product's pH. It may have a slightly fishy smell.
Methionine
Est. %0.3
Function
Origin
MethionineMethionine is a sulfur-containing amino acid that is a part of all the proteins in the body. It supports hair growth, but other than that there isn't much information about its functions in personal care products.
Valine
Est. %0.3
Function
Origin
ValineAn essential amino acid (meaning our body cannot make it on its own and we get it from food instead). Like some other amino acids, Valine is a part of the skin's Natural Moisturizing Factor.
Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Cysteine
Est. %0.3
Function
Origin
CysteineA multifunctional amino acid that acts as a reducing agent and an antioxidant.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Isoleucine
Est. %0.3
Function
Origin
IsoleucineA humectant moisturizing, essential amino acid that is a part of the skin's Natural Moisturizing Factor. It helps to increase water content on the skin’s surface and can increase the barrier repair effects of ceramides.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Tyrosine
Est. %0.3
Function
Origin
Tyrosine
Threonine
Est. %0.3
Function
Origin
ThreonineAn essential amino acid that may play a role in collagen production. However, more research is needed in order to confirm or deny these claims.
Phenylalanine
Est. %0.3
Function
Origin
PhenylalanineAn essential amino acid used in the treatment of vitiligo and other pigmentation issues. It is considered less effective than other anti-pigment ingredients and is often used in combination with them.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Histidine
Est. %0.3
Function
Origin
HistidineA humectant moisturizing amino acid with weak antioxidant effects that is a part of the skin’s Natural Moisturizing Factor. It can attract water to the skin’s surface and is slightly alkaline, thereby helping to balance a product's pH.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.