Tirtir Niacinamide 20% Serum Review

Tirtir Niacinamide 20% Serum
5.3
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
8.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Tirtir Niacinamide 20% Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Tirtir Niacinamide 20% Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.3 out of 10.
✅ Potent anti-wrinkle effect. With an anti-wrinkle rating of 8.5 out of 10, Tirtir Niacinamide 20% Serum is highly potent in reducing wrinkles.
✅ Soothing: Tirtir Niacinamide 20% Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of Tirtir Niacinamide 20% Serum

 
These are the key benefits you can expect from using Tirtir Niacinamide 20% Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Tirtir Niacinamide 20% Serum is quite moisturizing, with a moisturizing rating of 5.3 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Niacinamide (est. ≈20.0%), Glycerin (est. ≈4.0%) and Butylene Glycol (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣🟣 Potent Anti-Wrinkle Efficacy

According to CreamScan analysis, Tirtir Niacinamide 20% Serum has a very high anti-wrinkle rating of 8.5 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

1️⃣ Niacinamide (est. ≈20.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
2️⃣ Retinol (est. ≈0.1%),
 the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Tirtir Niacinamide 20% Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈20.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, Tirtir Niacinamide 20% Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈20.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Tirtir Niacinamide 20% Serum

 
CreamScan AI identified a few things to consider before adding Tirtir Niacinamide 20% Serum to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Retinol

This product contains retinol, which offers powerful anti-wrinkle benefits. The mechanism behind retinol’s action is boosting cell turnover. This process exposes new, more delicate skin, making it more vulnerable to sun damage.

As a result, using products with retinol may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To protect the skin, dermatologists recommend applying a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment, along with avoiding direct sun exposure. Retinol should be used at night, as it is sensitive to sunlight and can lose its potency when exposed to UV rays.

📌 Please always check the manufacturer's instructions for using the retinol-containing products, either on their website or product label.

Pros & Cons of Tirtir Niacinamide 20% Serum

 
Here’s an overview of the pros and cons of Tirtir Niacinamide 20% Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers potent anti-wrinkle efficacy thanks to Niacinamide and Retinol
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing Niacinamide
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to retinol
   

Summary: Tirtir Niacinamide 20% Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Tirtir Niacinamide 20% Serum
 is highly effective in treating wrinkles, featuring ingredients with solid, robust evidence of anti-wrinkle efficacy, in concentrations that may deliver a significant anti-wrinkle effect.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, Tirtir Niacinamide 20% Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
That said, there are some things about Tirtir Niacinamide 20% Serum worth noting.
 
This product contains retinol, the most powerful and well-researched non-prescription anti-wrinkle ingredient. However, retinol can make your skin more prone to sun damage and increase sensitivity, so it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
60
20
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Niacinamide
Function:
Origin:
Glycerin
Function:
Origin:
Butylene Glycol
Function:
Origin:
Propanediol
Function:
Origin:
Alpha-Arbutin
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Hydroxyacetophenone
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Tromethamine
Function:
Origin:
Glycereth-25 PCA Isostearate
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Macadamia Ternifolia Seed Oil
Function:
Origin:
Zea Mays (Corn) Kernel Extract
Function:
Origin:
Disodium EDTA
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Retinol
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Hydrolyzed Hyaluronic Acid
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Brassica Campestris (Rapeseed) Sterols
Function:
Origin:
Cholesterol
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Function:
Origin:
Aluminum/Magnesium Hydroxide Stearate
Function:
Origin:
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Function:
Origin:
Polysorbate 60
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Fructan
Function:
Origin:
Potassium Cetyl Phosphate
Function:
Origin:
Glucose
Function:
Origin:
Chitosan
Function:
Origin:
Tristearyl Citrate
Function:
Origin:
Glutathione
Function:
Origin:
Zinc PCA
Function:
Origin:

Ratings

All humectants
31.1
20
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.3
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 31.1 10
10.0
20
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.2 20
0.6
0.3
0.3
0.3
0.3
Moisturizing rating
5.3
Ingredient Est. % Benchmark Humectancy
20
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 31.1 10
10
All humectants
31.1
20
4
3
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
All occlusives 1.2 20
0.6
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 20 6
10 /10 0.4 0.1 2.5
Total
8.5
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
20
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Anti-wrinkle rating
8.5
Ingredient Est. % Benchmark
Rich in Antioxidants
20
1.5
1
0.3
0.3
0.3
0.3
0.3
All antioxidants 24 3 Rich in antioxidants
All antioxidants
24
Niacinamide
20
Alpha-Arbutin
1.5
Hydroxyacetophenone
1
Hyaluronic Acid
0.3
Hydrolyzed Hyaluronic Acid
0.3
Sodium Hyaluronate
0.3
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
0.3
Glutathione
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
20
All soothing 20 5 Rich in soothing
All soothing
20
20
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Niacinamide
Est. %20
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butylene Glycol
Est. %3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Propanediol
Est. %2
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Alpha-Arbutin
Est. %1.5
Function
Origin
Alpha-Arbutin
1,2-Hexanediol
Est. %1.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Hydroxyacetophenone
Est. %1
Function
Origin
HydroxyacetophenoneAn antioxidant compound that can be found in many plants, although it is manufactured synthetically for skincare purposes. It can boost the preservative action of other conservants.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Glycereth-25 PCA Isostearate
Est. %0.3
Function
Origin
Glycereth-25 PCA Isostearate
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Macadamia Ternifolia Seed Oil
Est. %0.3
Function
Origin
Macadamia Ternifolia Seed OilAn occlusive moisturizing and emollient oil extracted from macadamia nuts. It is clear and pale yellow with a pleasant nutty aroma and contains oleic and palmitoleic fatty acids, tocopherols, phytosterols, squalene, and polyphenols.
Zea Mays (Corn) Kernel Extract
Est. %0.3
Function
Origin
Zea Mays (Corn) Kernel Extract
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Retinol
Est. %0.1
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Hyaluronic Acid
Est. %0.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
Hydrolyzed Hyaluronic AcidA smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Brassica Campestris (Rapeseed) Sterols
Est. %0.3
Function
Origin
Brassica Campestris (Rapeseed) SterolsBrassica campestris sterols are a mixture of sterols (fat-like compounds) obtained from rapeseed oil. They are used as an emollient additive to the oil base of a cosmetic product. Read more about rapeseed oil here: Brassica Campestris (Rapeseed) Seed Oil.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Est. %0.3
Function
Origin
Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Aluminum/Magnesium Hydroxide Stearate
Est. %0.3
Function
Origin
Aluminum/Magnesium Hydroxide Stearate
Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate
Est. %0.3
Function
Origin
Pentaerythrityl Tetra-di-t-butyl HydroxyhydrocinnamateAn antioxidant that protects vulnerable ingredients from the damage caused by ultraviolet radiation, which can also lead to the generation of damaging free radical species.
Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Fructan
Est. %0.3
Function
Origin
Fructan
Potassium Cetyl Phosphate
Est. %0.3
Function
Origin
Potassium Cetyl PhosphateA powerful emulsifier that can even mix particularly problematic water and oil blends. It is also a surfactant perfect for cleansing products that effectively rinse off oil and dirt particles from the surface of the skin.
Glucose
Est. %0.3
Function
Origin
GlucoseA simple sugar that is also one of two components of sucrose, or table sugar. It is used as a humectant in skincare products. Glucose is also used to flavor lip care cosmetics because of its mildly sweet taste.
Chitosan
Est. %0.3
Function
Origin
ChitosanA film-forming polysaccharide derived from the shells of shrimp, crabs, and other crustaceans. It is a very special ingredient that is used to form protective films on wounds in order to promote wound healing.
Tristearyl Citrate
Est. %0.3
Function
Origin
Tristearyl Citrate
Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Zinc PCA
Est. %0.3
Function
Origin
Zinc PCAA two-part ingredient: Zinc helps to control sebum and bacteria in acne-prone skin, while skin-identical PCA is a moisturizing humectant. Zinc PCA may even boost collagen production and so is researched as a potential anti-wrinkle ingredient.