The Originote TXA 377 Dark Spot Serum Review

The Originote TXA 377 Dark Spot Serum
5.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does The Originote TXA 377 Dark Spot Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what The Originote TXA 377 Dark Spot Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.2 out of 10.
✅ Modest anti-wrinkle efficacy: The Originote TXA 377 Dark Spot Serum has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection

  

Key Benefits of The Originote TXA 377 Dark Spot Serum

 
These are the key benefits you can expect from using The Originote TXA 377 Dark Spot Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, The Originote TXA 377 Dark Spot Serum is quite moisturizing, with a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.3 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%), Butylene Glycol (est. ≈4.0%) and Niacinamide (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, The Originote TXA 377 Dark Spot Serum has a modest level of anti-wrinkle efficacy, rated 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈2.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, The Originote TXA 377 Dark Spot Serum also contains Beta-Glucan, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Beta-Glucan provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Beta-Glucan may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that The Originote TXA 377 Dark Spot Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of The Originote TXA 377 Dark Spot Serum

 
Here’s an overview of the pros and cons of The Originote TXA 377 Dark Spot Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: The Originote TXA 377 Dark Spot Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that The Originote TXA 377 Dark Spot Serum
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
The Originote TXA 377 Dark Spot Serum contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, The Originote TXA 377 Dark Spot Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Butylene Glycol
Function:
Origin:
Tranexamic Acid
Function:
Origin:
Niacinamide
Function:
Origin:
Rosa Damascena Flower Water
Function:
Origin:
Cyclopentasiloxane
Function:
Origin:
Glycereth-26
Function:
Origin:
Hydroxyacetophenone
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
PEG/PPG-17/6 Copolymer
Function:
Origin:
Sodium Acryloyldimethyltaurate Crosspolymer
Function:
Origin:
Methylpropanediol
Function:
Origin:
Methicone
Function:
Origin:
Phenylethyl Resorcinol
Function:
Origin:
Glycyrrhiza Uralensis (Licorice) Root Extract
Function:
Origin:
Allantoin
Function:
Origin:
Tremella Fuciformis Polysaccharide
Function:
Origin:
Portulaca Oleracea Flower/Leaf/Stem Extract
Function:
Origin:
Paeonia Lactiflora Extract
Function:
Origin:
Glyceryl Glucoside
Function:
Origin:
Polysorbate 80
Function:
Origin:
Propylene Glycol
Function:
Origin:
Bisabolol
Function:
Origin:
Osmanthus Fragrans Flower Extract
Function:
Origin:
Stephania Tetrandra Root Extract
Function:
Origin:
Beta-Glucan
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Phospholipids
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Daucus Carota Sativa (Carrot) Root Extract
Function:
Origin:
Ceramide NP
Function:
Origin:
Glutathione
Function:
Origin:
Panax Ginseng Root Extract
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:

Ratings

All humectants
14.5
6
4
2
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 14.5 10
10.0
6
4
2
1
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Humectancy
6
4
2
1
0.3
0.3
0.3
0.3
0.3
All humectants 14.5 10
10
All humectants
14.5
6
4
2
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
n/a
- 0.3 -
Total
3
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 4.7 3 Rich in antioxidants
All antioxidants
4.7
Niacinamide
2
Hydroxyacetophenone
0.3
Phenylethyl Resorcinol
0.3
Glycyrrhiza Uralensis (Licorice) Root Extract
0.3
Portulaca Oleracea Flower/Leaf/Stem Extract
0.3
Beta-Glucan
0.3
Daucus Carota Sativa (Carrot) Root Extract
0.3
Glutathione
0.3
Panax Ginseng Root Extract
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
0.3
0.3
All soothing 3.5 5 No
All soothing
3.5
2
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butylene Glycol
Est. %4
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Tranexamic Acid
Est. %3
Function
Origin
Tranexamic AcidA synthetic amino acid that is used as an astringent to stop the bleeding from small cuts. It also has proven anti-pigment and redness-reducing effects.
Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Rosa Damascena Flower Water
Est. %1.5
Function
Origin
Rosa Damascena Flower WaterA fragrant water that is leftover after the steam distillation of Damask rose petals. During this process, the essential oil floats to the surface of the water and is collected. The leftover water has a fresh, rosy scent.
Cyclopentasiloxane
Est. %1.3
Function
Origin
CyclopentasiloxaneA lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.
Glycereth-26
Est. %1
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Hydroxyacetophenone
Est. %0.3
Function
Origin
HydroxyacetophenoneAn antioxidant compound that can be found in many plants, although it is manufactured synthetically for skincare purposes. It can boost the preservative action of other conservants.
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
PEG/PPG-17/6 Copolymer
Est. %0.3
Function
Origin
PEG/PPG-17/6 CopolymerA synthetic polymer that has many uses. It can help add slip by itself and also supports silicone-based ingredients in various products.
Sodium Acryloyldimethyltaurate Crosspolymer
Est. %0.3
Function
Origin
Sodium Acryloyldimethyltaurate Crosspolymer
Methylpropanediol
Est. %0.3
Function
Origin
MethylpropanediolMethylpropanediol is a unique glycol that contains two primary hydroxyl groups. That makes methylpropanediol a powerful humectant and an excellent solvent.
Methicone
Est. %0.3
Function
Origin
MethiconeA silicone oil that can function as an occlusive moisturizer and emollient. Occasionally, methicone is used as a surface modifier for various pigments to improve the longevity and vibrancy of colorants.
Phenylethyl Resorcinol
Est. %0.3
Function
Origin
Phenylethyl ResorcinolA derivative of resorcinol whose anti-pigment activity is well-researched and backed by science. It is very light-sensitive and must be protected by packaging or careful formulation.
Glycyrrhiza Uralensis (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Uralensis (Licorice) Root ExtractA soothing and anti-pigment extract derived from a species of licorice with glycyrrhizin as the main active ingredient.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Tremella Fuciformis Polysaccharide
Est. %0.3
Function
Origin
Tremella Fuciformis Polysaccharide
Portulaca Oleracea Flower/Leaf/Stem Extract
Est. %0.3
Function
Origin
Portulaca Oleracea Flower/Leaf/Stem Extract
Paeonia Lactiflora Extract
Est. %0.3
Function
Origin
Paeonia Lactiflora Extract
Glyceryl Glucoside
Est. %0.3
Function
Origin
Glyceryl Glucoside
Polysorbate 80
Est. %0.3
Function
Origin
Polysorbate 80A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities.
Propylene Glycol
Est. %0.3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Bisabolol
Est. %0.3
Function
Origin
Bisabolol

An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.

Osmanthus Fragrans Flower Extract
Est. %0.3
Function
Origin
Osmanthus Fragrans Flower Extract
Stephania Tetrandra Root Extract
Est. %0.3
Function
Origin
Stephania Tetrandra Root Extract
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Phospholipids
Est. %0.3
Function
Origin
PhospholipidsA large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Daucus Carota Sativa (Carrot) Root Extract
Est. %0.3
Function
Origin
Daucus Carota Sativa (Carrot) Root ExtractAn antioxidant extract derived from carrots. It is a rich source of the orange-colored beta-carotene (pro-vitamin A). Carrot root extract is often added to skincare products that are aimed at providing a better suntan.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Panax Ginseng Root Extract
Est. %0.3
Function
Origin
Panax Ginseng Root ExtractDerived from the roots of the Korean Ginseng, this extract contains a mixture of antioxidant and soothing ginsenosides which are proven to reduce inflammation and treat eczema. The root is a major part of Chinese traditional medicine.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.