Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum

Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum
4.8
/ 10
Moisturizing
9.3 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Results you may expect from using Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum:

  • Moderate moisturizing. It has a moisturizing rating of 4.8 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum is effective in minimizing wrinkles.
  • Soothing: Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum has a moisturizing rating of 4.8 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.3 out of 10 and a very high humectancy of 9.3 out of 10, primarily due to the high content of Niacinamide (est. ≈4.0%) and Propanediol (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum has a high anti-wrinkle rating of 6.0 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈4.0%),
 one of the most effective and well-researched anti-wrinkle ingredients.
 
Among others, Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum also contains contains Bakuchiol and Ascorbyl Palmitate, two ingredients marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Perricone MD Hypoallergenic Clean Correction Smoothing Restorative Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈4.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
75
Water
6
Isononyl Isononanoate
4
Niacinamide
3
Polyglyceryl-4 Caprate
2
Propanediol
1.5
Glyceryl Stearate SE
1.3
Beta Vulgaris (Beet) Root Extract
1
Bakuchiol
0.3
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
0.3
Brassica Campestris (Rapeseed) Seed Oil
0.3
Caprylyl Glycol
0.3
1,2-Hexanediol
0.3
Phosphatidylcholine
0.3
Glycerin
0.3
Panthenol
0.3
Lactobacillus/Soybean Ferment Extract
0.3
Lycium Chinense Stem Extract
0.3
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Polyglyceryl-3 Diisostearate
0.3
Cucumis Sativus (Cucumber) Fruit Extract
0.3
Potassium Stearate
0.3
Citric Acid
0.3
Sorbitan Isostearate
0.3
Ocimum Sanctum Leaf Extract
0.3
Phaseolus Angularis Seed Extract
0.3
Lactic Acid
0.3
Lysine
0.3
Mannose
0.3
Sodium Mannose Phosphate
0.3
Althaea Officinalis Root Extract
0.3
Oryza Sativa (Rice) Bran Water
0.3
Xanthan Gum
0.3
Copper Sulfate
0.3
Proline
0.3
Pentylene Glycol
0.3
Tocopherol
0.3
Ascorbyl Palmitate
Est. %
Water
Function:
Origin:
Isononyl Isononanoate
Function:
Origin:
Niacinamide
Function:
Origin:
Polyglyceryl-4 Caprate
Function:
Origin:
Propanediol
Function:
Origin:
Glyceryl Stearate SE
Function:
Origin:
Beta Vulgaris (Beet) Root Extract
Function:
Origin:
Bakuchiol
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Brassica Campestris (Rapeseed) Seed Oil
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Phosphatidylcholine
Function:
Origin:
Glycerin
Function:
Origin:
Panthenol
Function:
Origin:
Lactobacillus/Soybean Ferment Extract
Function:
Origin:
Lycium Chinense Stem Extract
Function:
Origin:
Glycyrrhiza Glabra (Licorice) Root Extract
Function:
Origin:
Polyglyceryl-3 Diisostearate
Function:
Origin:
Cucumis Sativus (Cucumber) Fruit Extract
Function:
Origin:
Potassium Stearate
Function:
Origin:
Citric Acid
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Ocimum Sanctum Leaf Extract
Function:
Origin:
Phaseolus Angularis Seed Extract
Function:
Origin:
Lactic Acid
Function:
Origin:
Lysine
Function:
Origin:
Mannose
Function:
Origin:
Sodium Mannose Phosphate
Function:
Origin:
Althaea Officinalis Root Extract
Function:
Origin:
Oryza Sativa (Rice) Bran Water
Function:
Origin:
Xanthan Gum
Function:
Origin:
Copper Sulfate
Function:
Origin:
Proline
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Tocopherol
Function:
Origin:
Ascorbyl Palmitate
Function:
Origin:

Ratings

All humectants
9.3
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
4.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.3 10
9.3
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
4.8
Ingredient Est. % Benchmark Humectancy
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 9.3 10
9.3
All humectants
9.3
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 4 6
n/a
- 1 -
n/a
- 0.3 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
4
Bakuchiol
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1
Ascorbyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
4
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 8.1 3 Rich in antioxidants
All antioxidants
8.1
Niacinamide
4
Beta Vulgaris (Beet) Root Extract
1.3
Bakuchiol
1
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Ocimum Sanctum Leaf Extract
0.3
Phaseolus Angularis Seed Extract
0.3
Althaea Officinalis Root Extract
0.3
Tocopherol
0.3
Ascorbyl Palmitate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
0.3
0.3
0.3
0.3
0.3
All soothing 5.5 5 Rich in soothing
All soothing
5.5
4
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Isononyl Isononanoate
Est. %6
Function
Origin
Isononyl IsononanoateAn ester of a branched fatty acid with a branched fatty alcohol. It is an easily spreadable emollient that has a silky, dry, non-greasy feel on the skin.
Niacinamide
Est. %4
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Polyglyceryl-4 Caprate
Est. %3
Function
Origin
Polyglyceryl-4 CaprateA natural surfactant that softens the appearance of skin and forms oil and water mixtures.
Propanediol
Est. %2
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Glyceryl Stearate SE
Est. %1.5
Function
Origin
Glyceryl Stearate SEAn emulsifier, where the SE stands for self-emulsifying. Emulsions containing glyceryl stearate SE often impart a smooth, velvety feel upon the skin.
Beta Vulgaris (Beet) Root Extract
Est. %1.3
Function
Origin
Beta Vulgaris (Beet) Root ExtractA purple-red extract with antioxidant activity that is obtained from red beetroot.
Bakuchiol
Est. %1
Function
Origin
BakuchiolA newly discovered bioactive obtained from the seeds of Babchi. It boosts collagen production like retinol, but with fewer side effects. Its effects include reduced wrinkles and faded pigmentation.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Brassica Campestris (Rapeseed) Seed Oil
Est. %0.3
Function
Origin
Brassica Campestris (Rapeseed) Seed OilAn occlusive moisturizing rapeseed or canola seed oil. It mainly consists of fatty acids and lutein, and contains the highest amount of antioxidant phenolics among all vegetable oils.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Phosphatidylcholine
Est. %0.3
Function
Origin
PhosphatidylcholineA special emulsifying lipid used to create delivery spheres called liposomes.
Glycerin
Est. %0.3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Lactobacillus/Soybean Ferment Extract
Est. %0.3
Function
Origin
Lactobacillus/Soybean Ferment ExtractA biotechnological ingredient that is essentially soy milk fermented with lactic acid bacteria. It may help to treat skin pigmentation but more research is needed to support this claim.
Lycium Chinense Stem Extract
Est. %0.3
Function
Origin
Lycium Chinense Stem Extract
Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Glabra (Licorice) Root ExtractAn extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Polyglyceryl-3 Diisostearate
Est. %0.3
Function
Origin
Polyglyceryl-3 DiisostearateA vegetable-based ingredient that stabilizes mixtures of oil and water.
Cucumis Sativus (Cucumber) Fruit Extract
Est. %0.3
Function
Origin
Cucumis Sativus (Cucumber) Fruit ExtractA soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Potassium Stearate
Est. %0.3
Function
Origin
Potassium Stearate
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Ocimum Sanctum Leaf Extract
Est. %0.3
Function
Origin
Ocimum Sanctum Leaf ExtractAn extract derived from the leaves of Holy Basil, also known as Tulsi, a traditional herb used in Ayurveda medicine. It contains antioxidant and anti-inflammatory rosmarinic acid, galic acid, flavonoids, and a sweet-scented essential oil.
Phaseolus Angularis Seed Extract
Est. %0.3
Function
Origin
Phaseolus Angularis Seed Extract
Lactic Acid
Est. %0.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Lysine
Est. %0.3
Function
Origin
LysineA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It is slightly alkaline and helps to balance the product's pH. It may have a slightly fishy smell.
Mannose
Est. %0.3
Function
Origin
Mannose
Sodium Mannose Phosphate
Est. %0.3
Function
Origin
Sodium Mannose Phosphate
Althaea Officinalis Root Extract
Est. %0.3
Function
Origin
Althaea Officinalis Root ExtractA soothing extract obtained from the marsh-mallow plant. It contains anti-inflammatory polyphenols and antioxidant polysaccharides.
Oryza Sativa (Rice) Bran Water
Est. %0.3
Function
Origin
Oryza Sativa (Rice) Bran Water
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Copper Sulfate
Est. %0.3
Function
Origin
Copper Sulfate
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Pentylene Glycol
Est. %0.3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Ascorbyl Palmitate
Est. %0.3
Function
Origin
Ascorbyl PalmitateA form of vitamin C derived from ascorbic acid and palmitic acid. It is more stable and less irritating than ascorbic acid. Unfortunately, Ascorbyl Palmitate lacks the studies to prove its anti-wrinkle efficacy.