Osmosis Beauty Clarify Blemish Retinal Serum Review

Osmosis Beauty Clarify Blemish Retinal Serum
4.9
/ 10
Moisturizing
9.6 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
10Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Ingredients

Osmosis Beauty Clarify Blemish Retinal Serum Ingredients

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Full Ingredient List (INCI):

Water, Niacinamide, Phosphatidylcholine, Glycerin, Mandelic Acid, Epilobium Angustifolium Flower/Leaf/Stem Extract, Chlorella Vulgaris Extract, Lactic Acid, Chamomilla Recutita (Matricaria) Flower Extract, Cucumis Sativus (Cucumber) Fruit Extract, Olea Europaea (Olive) Leaf Extract, Ocimum Basilicum (Basil) Leaf Extract, Artemisia Umbelliformis Extract, Hyssopus Officinalis Extract, Retinal, Citrus Paradisi (Grapefruit) Peel Oil, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Rubus Chamaemorus Seed Oil, Beta-Glucan, Rosmarinus Officinalis (Rosemary) Leaf Oil, Eucalyptus Globulus Leaf Oil, Lonicera Caprifolium (Honeysuckle) Flower Extract, Lonicera Japonica (Honeysuckle) Flower Extract, Cyclodextrin, Xanthan Gum, Pentylene Glycol, Sodium Hydroxide, Benzyl Alcohol
Review

Does Osmosis Beauty Clarify Blemish Retinal Serum Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Osmosis Beauty Clarify Blemish Retinal Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 4.9 out of 10.
✅ Potent anti-wrinkle effect with the highest possible efficacy rating. With an anti-wrinkle rating of 10 out of 10, Osmosis Beauty Clarify Blemish Retinal Serum is highly potent in reducing wrinkles.
✅ Soothing: Osmosis Beauty Clarify Blemish Retinal Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of Osmosis Beauty Clarify Blemish Retinal Serum

 
These are the key benefits you can expect from using Osmosis Beauty Clarify Blemish Retinal Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Osmosis Beauty Clarify Blemish Retinal Serum is quite moisturizing, with a moisturizing rating of 4.9 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a very high humectancy of 9.6 out of 10, primarily due to the high content of Niacinamide (est. ≈5.0%) and Glycerin (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣🟣 Potent Anti-Wrinkle Efficacy

According to CreamScan analysis, Osmosis Beauty Clarify Blemish Retinal Serum has a maximum anti-wrinkle rating of 10 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

1️⃣ Niacinamide (est. ≈5.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
2️⃣ Retinal (est. ≈0.05%),
 also known as retinaldehyde, is a potent retinoid with anti-wrinkle efficacy confirmed by a single clinical study involving 125 participants (Creidi et al.). This study demonstrated that a cream containing 0.05% retinal reduced the average wrinkle depth by 8% after 18 weeks of use, compared to a vehicle (the same formulation without retinal).
 
Among others, Osmosis Beauty Clarify Blemish Retinal Serum also contains contains Olea Europaea (Olive) Leaf Extract and Beta-Glucan, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Osmosis Beauty Clarify Blemish Retinal Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈5.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, Osmosis Beauty Clarify Blemish Retinal Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈5.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Osmosis Beauty Clarify Blemish Retinal Serum

 
CreamScan identified a few things to consider before adding Osmosis Beauty Clarify Blemish Retinal Serum to your skincare routine:
 

⚠️ If It’s an Exfoliator, It May Increase Skin Photosensitivity Due to Lactic Acid

This product contains lactic acid, a popular AHA known for its ability to gently exfoliate and brighten the skin. It works by removing dead skin cells, revealing new, more delicate skin that is more vulnerable to sun damage.

In smaller quantities, lactic acid is often used as a pH adjuster and may not significantly contribute to exfoliation. However, at higher concentrations, it functions as an effective exfoliant with benefits and risks similar to other AHAs. Products with AHAs, including lactic acid, may increase skin sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

If this product is designed for exfoliation, applying a broad-spectrum sunscreen with at least SPF 30 daily is essential to protect your skin. Always check the label or the manufacturer’s website for specific usage instructions.

Pros & Cons of Osmosis Beauty Clarify Blemish Retinal Serum

 
Here’s an overview of the pros and cons of Osmosis Beauty Clarify Blemish Retinal Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers potent anti-wrinkle efficacy with the highest possible rating of 10 out of 10 thanks to Niacinamide and Retinal
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients, specifically Niacinamide
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Osmosis Beauty Clarify Blemish Retinal Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Osmosis Beauty Clarify Blemish Retinal Serum
 is highly effective in treating wrinkles, featuring ingredients with solid, robust evidence of anti-wrinkle efficacy, in concentrations that may deliver a significant anti-wrinkle effect.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, Osmosis Beauty Clarify Blemish Retinal Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
That said, there are some things about Osmosis Beauty Clarify Blemish Retinal Serum worth noting.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
75
5
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.05
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Niacinamide
Function:
Origin:
Phosphatidylcholine
Function:
Origin:
Glycerin
Function:
Origin:
Mandelic Acid
Function:
Origin:
Epilobium Angustifolium Flower/Leaf/Stem Extract
Function:
Origin:
Chlorella Vulgaris Extract
Function:
Origin:
Lactic Acid
Function:
Origin:
Chamomilla Recutita (Matricaria) Flower Extract
Function:
Origin:
Cucumis Sativus (Cucumber) Fruit Extract
Function:
Origin:
Olea Europaea (Olive) Leaf Extract
Function:
Origin:
Ocimum Basilicum (Basil) Leaf Extract
Function:
Origin:
Artemisia Umbelliformis Extract
Function:
Origin:
Hyssopus Officinalis Extract
Function:
Origin:
Retinal
Function:
Origin:
Citrus Paradisi (Grapefruit) Peel Oil
Function:
Origin:
Melaleuca Alternifolia (Tea Tree) Leaf Oil
Function:
Origin:
Rubus Chamaemorus Seed Oil
Function:
Origin:
Beta-Glucan
Function:
Origin:
Rosmarinus Officinalis (Rosemary) Leaf Oil
Function:
Origin:
Eucalyptus Globulus Leaf Oil
Function:
Origin:
Lonicera Caprifolium (Honeysuckle) Flower Extract
Function:
Origin:
Lonicera Japonica (Honeysuckle) Flower Extract
Function:
Origin:
Cyclodextrin
Function:
Origin:
Xanthan Gum
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Benzyl Alcohol
Function:
Origin:

Ratings

All humectants
9.6
5
3
1
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
4.9
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.6 10
9.6
5
3
1
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
4.9
Ingredient Est. % Benchmark Humectancy
5
3
1
0.3
0.3
All humectants 9.6 10
9.6
All humectants
9.6
5
3
1
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 5 6
5 /10 0.05 0.05 5
n/a
- 0.3 -
n/a
- 0.3 -
Total
10
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
5
Retinal
5
Ingredient anti-wrinkle power
5 /10
when present at, %
0.05
in this formula, est. %
0.05
Olea Europaea (Olive) Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
10
Ingredient Est. % Benchmark
Rich in Antioxidants
5
1.5
1.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 9.6 3 Rich in antioxidants
All antioxidants
9.6
Niacinamide
5
Epilobium Angustifolium Flower/Leaf/Stem Extract
1.5
Chlorella Vulgaris Extract
1.3
Chamomilla Recutita (Matricaria) Flower Extract
0.3
Olea Europaea (Olive) Leaf Extract
0.3
Melaleuca Alternifolia (Tea Tree) Leaf Oil
0.3
Beta-Glucan
0.3
Rosmarinus Officinalis (Rosemary) Leaf Oil
0.3
Lonicera Japonica (Honeysuckle) Flower Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
5
0.3
0.3
0.3
0.3
0.3
All soothing 6.5 5 Rich in soothing
All soothing
6.5
5
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Niacinamide
Est. %5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Phosphatidylcholine
Est. %4
Function
Origin
PhosphatidylcholineA special emulsifying lipid used to create delivery spheres called liposomes.
Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Mandelic Acid
Est. %2
Function
Origin
Mandelic AcidDerived from almonds, this ingredient is one of the gentlest AHAs and is used for its exfoliating and antimicrobial properties. It is particularly beneficial for acne but also helps to treat post-inflammatory hyperpigmentation.
Epilobium Angustifolium Flower/Leaf/Stem Extract
Est. %1.5
Function
Origin
Epilobium Angustifolium Flower/Leaf/Stem ExtractAn extract from a plant known in North America as Fireweed and in Europe as Willowherb. It is commonly used in traditional herbal medicine. Due to its abundant content of tannins and flavonoids, it has great astringent and antioxidant properties.
Chlorella Vulgaris Extract
Est. %1.3
Function
Origin
Chlorella Vulgaris ExtractA dried mass of tiny, single-cell green algae. It is widely used as a food source or dietary supplement since it is rich in proteins, amino acids, minerals, and vitamins. This dark green extract is used as an antioxidant agent in skincare.
Lactic Acid
Est. %1
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Chamomilla Recutita (Matricaria) Flower Extract
Est. %0.3
Function
Origin
Chamomilla Recutita (Matricaria) Flower ExtractDerived from German chamomile flowers, this extract is especially known for its anti-inflammatory and soothing benefits. It contains two soothing compounds called chamazulene and bisabolol, as well as antioxidant flavonoids.
Cucumis Sativus (Cucumber) Fruit Extract
Est. %0.3
Function
Origin
Cucumis Sativus (Cucumber) Fruit ExtractA soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Olea Europaea (Olive) Leaf Extract
Est. %0.3
Function
Origin
Olea Europaea (Olive) Leaf ExtractAn antioxidant and fragrant extract from the leaves of the olive tree. It contains a promising anti-aging compound called Oleuropein, and a prospective anti-pigment compound called Cornoside.
Ocimum Basilicum (Basil) Leaf Extract
Est. %0.3
Function
Origin
Ocimum Basilicum (Basil) Leaf Extract
Artemisia Umbelliformis Extract
Est. %0.3
Function
Origin
Artemisia Umbelliformis Extract
Hyssopus Officinalis Extract
Est. %0.3
Function
Origin
Hyssopus Officinalis Extract
Retinal
Est. %0.05
Function
Origin
Retinal

A potent ingredient of the retinoid group with confirmed anti-wrinkle capabilities.

Citrus Paradisi (Grapefruit) Peel Oil
Est. %0.3
Function
Origin
Citrus Paradisi (Grapefruit) Peel Oil

This oil is obtained from the peels of pink grapefruits. It contains fragrant limonene, which gives the oil a fresh and clean, citrusy scent.

Melaleuca Alternifolia (Tea Tree) Leaf Oil
Est. %0.3
Function
Origin
Melaleuca Alternifolia (Tea Tree) Leaf OilA fragrant and antioxidant essential tea tree oil praised for its antiseptic and antimicrobial properties. Tea tree oil helps to treat acne, inflamed skin, and small wounds. It might, however, cause allergies and skin irritations.
Rubus Chamaemorus Seed Oil
Est. %0.3
Function
Origin
Rubus Chamaemorus Seed Oil
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Rosmarinus Officinalis (Rosemary) Leaf Oil
Est. %0.3
Function
Origin
Rosmarinus Officinalis (Rosemary) Leaf OilAn essential oil distilled from the leaves of rosemary. It is used as a fragrance in skincare and has a spicy, earthy, camphoraceous scent. It also has antioxidant properties according to some research.
Eucalyptus Globulus Leaf Oil
Est. %0.3
Function
Origin
Eucalyptus Globulus Leaf OilAn essential oil extracted from the leaves of the Eucalyptus globulus, a tall, evergreen, Australian tree with waxy leaves. It mostly consists of cineole – which has potent antimicrobial and anti-inflammatory activity.
Lonicera Caprifolium (Honeysuckle) Flower Extract
Est. %0.3
Function
Origin
Lonicera Caprifolium (Honeysuckle) Flower ExtractA fragrant extract derived from the flowers of the Italian honeysuckle. It has a pleasant, sweet, floral scent. Not much is known about its compounds and their functions.
Lonicera Japonica (Honeysuckle) Flower Extract
Est. %0.3
Function
Origin
Lonicera Japonica (Honeysuckle) Flower ExtractAn extract from the white flowers of the Japanese honeysuckle. Apart from an essential oil responsible for its jasmine-like scent, the extract also contains antioxidant and anti-inflammatory iridoids, flavonoids, and phenolic acids.
Cyclodextrin
Est. %0.3
Function
Origin
CyclodextrinA naturally derived ingredient with the ability to absorb other compounds and remove harmful metal ions from water.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Pentylene Glycol
Est. %0.3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Benzyl Alcohol
Est. %0.3
Function
Origin
Benzyl Alcohol

A multifunctional ingredient that is supplied as a clear, colorless liquid. Its main function is as a flavoring agent and fragrance. It also acts as a broad-spectrum preservative, solvent, and viscosity-controlling agent that thins the product.