NeoStrata Glycolic Renewal Serum Review

NeoStrata Glycolic Renewal Serum
3.6
/ 10
Moisturizing
7.1 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
1.5Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does NeoStrata Glycolic Renewal Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what NeoStrata Glycolic Renewal Serum has to offer:
 
✅ Light moisturizing. It has a moisturizing rating of 3.6 out of 10.
✅ Slight anti-wrinkle effect: NeoStrata Glycolic Renewal Serum has an anti-wrinkle rating of 1.5 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

  

Key Benefits of NeoStrata Glycolic Renewal Serum

 
These are the key benefits you can expect from using NeoStrata Glycolic Renewal Serum:
 

🔵 Lightweight Purely Humectant Moisturizer Well-Suited for Oily Skin

According to CreamScan analysis, NeoStrata Glycolic Renewal Serum is lightly moisturizing, with a moisturizing rating of 3.6 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a high humectancy of 7.1 out of 10, primarily due to the high content of Glycereth-7 Trimethyl Ether (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

❗️ Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Enhancement for Any Skincare Routine

But it’s not limited to oily skin - such a humectant enhancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, NeoStrata Glycolic Renewal Serum has a slight anti-wrinkle rating of 1.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Glycolic Acid (est. ≈10.0%),
 a highly effective ingredient in peelings but with moderate anti-wrinkle efficacy in leave-on skincare products, as supported by a single clinical study. This study, involving 72 participants (Thibault et al.), demonstrated that a lotion with 5% GA reduced the fine wrinkling score by 6% after 34 days of use, compared to a vehicle (the same formulation without GA).
 
Among others, NeoStrata Glycolic Renewal Serum also contains Lactobionic Acid, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Lactobionic Acid provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Lactobionic Acid may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: NeoStrata Glycolic Renewal Serum

 
CreamScan AI identified a few things to consider before adding NeoStrata Glycolic Renewal Serum to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Glycolic Acid

This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. Its action works by removing dead skin cells, revealing new, more delicate skin that is particularly vulnerable to sun damage.

As a result, using products with glycolic acid, regardless of concentration, may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To counteract this increased sun sensitivity, apply a broad-spectrum sunscreen with at least SPF 30 daily to protect your skin during glycolic acid treatment.

❗️Please always check the manufacturer's instructions for using the product, either on their website or product label.

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using NeoStrata Glycolic Renewal Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of NeoStrata Glycolic Renewal Serum

 
Here’s an overview of the pros and cons of NeoStrata Glycolic Renewal Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing well-suited for oily skin
✅ As part of a routine: A humectant moisturizing enhancement, beneficial for any skin type
✅ Lightweight texture
Provides slight anti-wrinkle efficacy
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to glycolic acid
⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
   

Summary: NeoStrata Glycolic Renewal Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that NeoStrata Glycolic Renewal Serum
, when used alone, delivers lightweight, humectant-rich moisturizing that is well-suited for oily skin. As part of a moisturizing routine, it provides a humectant enhancement, beneficial for all skin types.
 
NeoStrata Glycolic Renewal Serum contains ingredients with proven evidence of anti-wrinkle efficacy that may offer a slight anti-wrinkle effect. As a result, you can expect a positive, though relatively minimal, impact on wrinkles.
 
 
That said, there are some things about NeoStrata Glycolic Renewal Serum worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 
This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. However, glycolic acid - regardless of concentration - can increase skin sensitivity, making it more prone to sunburn or irritation when exposed to UV rays. Therefore, it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 during glycolic acid treatment.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
70
10.1
10
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Hydrolyzed Vegetable Protein
Function:
Origin:
Glycolic Acid
Function:
Origin:
Glycereth-7 Trimethyl Ether
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Glycerin
Function:
Origin:
Lactobionic Acid
Function:
Origin:
Arginine
Function:
Origin:
Xanthan Gum
Function:
Origin:
Hibiscus Sabdariffa Flower Extract
Function:
Origin:
Epigallocatechin Gallate
Function:
Origin:
Sodium Bisulfite
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Chlorphenesin
Function:
Origin:
Fragrance
Function:
Origin:
Benzyl Benzoate
Function:
Origin:
Linalool
Function:
Origin:
Hexyl Cinnamal
Function:
Origin:
Geraniol
Function:
Origin:

Ratings

All humectants
7.1
3
1.5
1.3
1
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
3.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.1 10
7.1
3
1.5
1.3
1
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
3.6
Ingredient Est. % Benchmark Humectancy
3
1.5
1.3
1
0.3
All humectants 7.1 10
7.1
All humectants
7.1
3
1.5
1.3
1
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 10 1.5
n/a
- 1.3 -
Total
1.5
Glycolic Acid
1.5
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
10
Lactobionic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.3
Anti-wrinkle rating
1.5
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
All antioxidants 0.9 3 No
All antioxidants
0.9
Hibiscus Sabdariffa Flower Extract
0.3
Epigallocatechin Gallate
0.3
Sodium Bisulfite
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Hydrolyzed Vegetable Protein
Est. %10.1
Function
Origin
Hydrolyzed Vegetable ProteinA blanket term used for plant-based proteins that have been processed into smaller chunks. They add to the skincare product's film-forming and water-binding properties.
Glycolic Acid
Est. %10
Function
Origin
Glycolic Acid

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Glycereth-7 Trimethyl Ether
Est. %3
Function
Origin
Glycereth-7 Trimethyl Ether
Sodium Hydroxide
Est. %2
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Lactobionic Acid
Est. %1.3
Function
Origin
Lactobionic AcidA very gentle and non-irritating PHA derived from lactic acid. It has exfoliating and humectant properties and can improve skin elasticity.
Arginine
Est. %1
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Hibiscus Sabdariffa Flower Extract
Est. %0.3
Function
Origin
Hibiscus Sabdariffa Flower ExtractDerived from bright red hibiscus flowers, this extract contains anthocyanins (red plant pigments), antioxidant flavonoids, and high amounts of organic acids.
Epigallocatechin Gallate
Est. %0.3
Function
Origin
Epigallocatechin GallateA bioactive compound isolated from green tea with numerous beneficial effects. It is an astringent and antioxidant and can help the skin to heal, reduce redness, and treat UV-induced damage.
Sodium Bisulfite
Est. %0.3
Function
Origin
Sodium BisulfiteAn inorganic salt that kills bacteria and protects against oxidation.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Chlorphenesin
Est. %0.3
Function
Origin
ChlorphenesinA preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Benzyl Benzoate
Est. %0.3
Function
Origin
Benzyl BenzoateA fragrance ingredient with a fruity and woody scent. It is considered an allergen according to the International Fragrance Association (IFRA), which means that care must be taken when determining usage levels in skincare products.
Linalool
Est. %0.3
Function
Origin
LinaloolA fragrant, volatile compound naturally present in many essential oils. It has a pleasant scent and is often used in skincare products as a fragrance. People with sensitive skin should try to avoid it, or at least do a patch test before using it.
Hexyl Cinnamal
Est. %0.3
Function
Origin
Hexyl Cinnamal

A synthetic scent ingredient that produces a jasmine-like fragrance. According to the International Fragrance Association (IFRA), hexyl cinnamal is a skin sensitizer and allergen and so its use in skincare should be limited.

Geraniol
Est. %0.3
Function
Origin
Geraniol

A fragrant, volatile, plant-based, liquid chemical that can be naturally found in many essential oils (specifically rose, palmarosa, citronella). It has a rose-like scent. It is a potential irritant and may cause an allergic reaction in some people.