Miguhara Anti-wrinkle Effect Ampoule Origin Review

Miguhara Anti-wrinkle Effect Ampoule Origin
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Rich
in Antioxidants
Review

Does Miguhara Anti-wrinkle Effect Ampoule Origin Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Miguhara Anti-wrinkle Effect Ampoule Origin has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Antioxidant protection.

Key Benefits of Miguhara Anti-wrinkle Effect Ampoule Origin

 
These are the key benefits you can expect from using Miguhara Anti-wrinkle Effect Ampoule Origin:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Miguhara Anti-wrinkle Effect Ampoule Origin is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%) and Hydrolyzed Collagen (est. ≈4.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Miguhara Anti-wrinkle Effect Ampoule Origin is rich (> 3%) in antioxidants, specifically Panax Ginseng Root Extract (est. ≈1.5%), Ophiopogon Japonicus Root Extract (est. ≈1.3%), Platycodon Grandiflorus Root Extract (est. ≈1.0%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Miguhara Anti-wrinkle Effect Ampoule Origin

 
CreamScan AI identified a few things to consider before adding Miguhara Anti-wrinkle Effect Ampoule Origin to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Miguhara Anti-wrinkle Effect Ampoule Origin as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Miguhara Anti-wrinkle Effect Ampoule Origin is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Acetyl Hexapeptide-8 and Adenosine, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically exclude the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were accessible to the CreamScan team at the time of publication.

Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Miguhara Anti-wrinkle Effect Ampoule Origin

 
Here’s an overview of the pros and cons of Miguhara Anti-wrinkle Effect Ampoule Origin to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage

Cons: 

  • Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
  • Questionable anti-wrinkle efficacy

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Rosa Centifolia Flower Water
Function:
Origin:
Glycerin
Function:
Origin:
Hydrolyzed Collagen
Function:
Origin:
Natto Gum
Function:
Origin:
Wheat Amino Acids
Function:
Origin:
Panax Ginseng Root Extract
Function:
Origin:
Ophiopogon Japonicus Root Extract
Function:
Origin:
Platycodon Grandiflorus Root Extract
Function:
Origin:
Glycyrrhiza Glabra (Licorice) Root Extract
Function:
Origin:
Astragalus Membranaceus Root Extract
Function:
Origin:
Zingiber Officinale (Ginger) Root Extract
Function:
Origin:
Lonicera Japonica (Honeysuckle) Flower Extract
Function:
Origin:
Zanthoxylum Piperitum Fruit Extract
Function:
Origin:
Pulsatilla Koreana Extract
Function:
Origin:
Citrus Paradisi (Grapefruit) Fruit Extract
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Dioscorea Opposita Root Extract
Function:
Origin:
Hydroxyethylcellulose
Function:
Origin:
Gardenia Florida Oil
Function:
Origin:
Tremella Fuciformis Sporocarp Extract
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Xanthan Gum
Function:
Origin:
Adenosine
Function:
Origin:
Disodium EDTA
Function:
Origin:

Ratings

All humectants
12.5
6
4
1.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.5 10
10.0
6
4
1.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
1.3
0.3
0.3
0.3
0.3
All humectants 12.5 10
10
All humectants
12.5
6
4
1.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.9 3 Rich in antioxidants
All antioxidants
5.9
Panax Ginseng Root Extract
1.5
Ophiopogon Japonicus Root Extract
1.3
Platycodon Grandiflorus Root Extract
1
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Zingiber Officinale (Ginger) Root Extract
0.3
Lonicera Japonica (Honeysuckle) Flower Extract
0.3
Zanthoxylum Piperitum Fruit Extract
0.3
Citrus Paradisi (Grapefruit) Fruit Extract
0.3
Sodium Hyaluronate
0.3
Tremella Fuciformis Sporocarp Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
1.5
0.3
0.3
0.3
0.3
All soothing 4.7 5 No
All soothing
4.7
2
1.5
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Rosa Centifolia Flower Water
Est. %75
Function
Origin
Rosa Centifolia Flower WaterRosa centifolia flower water is fragrant water that is leftover after the steam distillation of the rose petals from the Rosa centifolia – the Provence rose or cabbage rose (referring to its rich, multi-petal flower head). Read more on rose oil here: Rosa Damascena Flower oil.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Hydrolyzed Collagen
Est. %4
Function
Origin
Hydrolyzed Collagen

A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.

Natto Gum
Est. %3
Function
Origin
Natto Gum
Wheat Amino Acids
Est. %2
Function
Origin
Wheat Amino Acids
Panax Ginseng Root Extract
Est. %1.5
Function
Origin
Panax Ginseng Root ExtractDerived from the roots of the Korean Ginseng, this extract contains a mixture of antioxidant and soothing ginsenosides which are proven to reduce inflammation and treat eczema. The root is a major part of Chinese traditional medicine.
Ophiopogon Japonicus Root Extract
Est. %1.3
Function
Origin
Ophiopogon Japonicus Root ExtractA moisturizing extract derived from the roots of the dwarf lilyturf, also known as mondo grass. It is rich in humectant polysaccharides and contains anti-inflammatory and antioxidant compounds.
Platycodon Grandiflorus Root Extract
Est. %1
Function
Origin
Platycodon Grandiflorus Root Extract
Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Glabra (Licorice) Root ExtractAn extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Astragalus Membranaceus Root Extract
Est. %0.3
Function
Origin
Astragalus Membranaceus Root Extract
Zingiber Officinale (Ginger) Root Extract
Est. %0.3
Function
Origin
Zingiber Officinale (Ginger) Root ExtractA fragrant and anti-inflammatory extract derived from ginger roots. It is a major part of Chinese traditional medicine. In can increase blood circulation, which helps with skin healing and skin metabolism.
Lonicera Japonica (Honeysuckle) Flower Extract
Est. %0.3
Function
Origin
Lonicera Japonica (Honeysuckle) Flower ExtractAn extract from the white flowers of the Japanese honeysuckle. Apart from an essential oil responsible for its jasmine-like scent, the extract also contains antioxidant and anti-inflammatory iridoids, flavonoids, and phenolic acids.
Zanthoxylum Piperitum Fruit Extract
Est. %0.3
Function
Origin
Zanthoxylum Piperitum Fruit ExtractA pepper extract that is claimed to have antibacterial and antioxidant properties.
Pulsatilla Koreana Extract
Est. %0.3
Function
Origin
Pulsatilla Koreana ExtractAn extract derived from the Korean pasque flower. It contains various saponins with antimicrobial properties and has been successfully tested against bacteria involved with acne.
Citrus Paradisi (Grapefruit) Fruit Extract
Est. %0.3
Function
Origin
Citrus Paradisi (Grapefruit) Fruit Extract

A fragrant extract derived from grapefruit peels. It mainly contains essential oil and various antioxidant organic acids and flavonoids. Limonene is responsible for its citrusy scent.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Dioscorea Opposita Root Extract
Est. %0.3
Function
Origin
Dioscorea Opposita Root Extract
Hydroxyethylcellulose
Est. %0.3
Function
Origin
HydroxyethylcelluloseA naturally-derived thickener that can form clear gel textures without the slimy feeling, unlike some other natural gel-formers.
Gardenia Florida Oil
Est. %0.3
Function
Origin
Gardenia Florida Oil
Tremella Fuciformis Sporocarp Extract
Est. %0.3
Function
Origin
Tremella Fuciformis Sporocarp ExtractA fungi extract. The mushroom contains various proteins, fiber, and humectant and antioxidant polysaccharides - which help to restore the water and collagen content in the skin.
Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.