Mediheal N.M.F Aquaring Ampoule Mask REX Review

Mediheal N.M.F Aquaring Ampoule Mask REX
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Ingredients

Mediheal N.M.F Aquaring Ampoule Mask REX Ingredients

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Full Ingredient List (INCI):

Water, Glycereth-26, PEG/PPG-17/6 Copolymer, Glycerin, Niacinamide, Sodium Hyaluronate, 1,2-Hexanediol, Polyglutamic Acid, Panthenol, Trehalose, Betaine, Hydroxyethyl Urea, Rosa Centifolia Flower Water, Fomes Officinalis (Mushroom) Extract, Hamamelis Virginiana (Witch Hazel) Water, Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract, Glutamine, Glutamic Acid, Arginine, Alanine, Phenylalanine, Portulaca Oleracea Extract, Hydrolyzed Collagen, Aloe Barbadensis Leaf Juice, Beta-Glucan, Xanthan Gum, Butylene Glycol, Boswellia Serrata Resin Extract, Salix Alba (Willow) Bark Extract, Carbomer, Allantoin, Polysorbate 80, Adenosine, Disodium EDTA, Tocopheryl Acetate, Fragrance
Review

Does Mediheal N.M.F Aquaring Ampoule Mask REX Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Mediheal N.M.F Aquaring Ampoule Mask REX has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
✅ Modest anti-wrinkle efficacy: Mediheal N.M.F Aquaring Ampoule Mask REX has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection

  

Key Benefits of Mediheal N.M.F Aquaring Ampoule Mask REX

 
These are the key benefits you can expect from using Mediheal N.M.F Aquaring Ampoule Mask REX:
 

🔵 Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Mediheal N.M.F Aquaring Ampoule Mask REX is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycereth-26 (est. ≈6.0%), Glycerin (est. ≈3.0%) and Niacinamide (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

📌 Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Mediheal N.M.F Aquaring Ampoule Mask REX has a modest level of anti-wrinkle efficacy, rated 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈2.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Mediheal N.M.F Aquaring Ampoule Mask REX also contains contains Beta-Glucan and Adenosine, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Mediheal N.M.F Aquaring Ampoule Mask REX is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Mediheal N.M.F Aquaring Ampoule Mask REX

 
CreamScan identified a few things to consider before adding Mediheal N.M.F Aquaring Ampoule Mask REX to your skincare routine:
 

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Mediheal N.M.F Aquaring Ampoule Mask REX as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Mediheal N.M.F Aquaring Ampoule Mask REX

 
Here’s an overview of the pros and cons of Mediheal N.M.F Aquaring Ampoule Mask REX to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
   

Summary: Mediheal N.M.F Aquaring Ampoule Mask REX

 
Based on the ingredient list analysis, CreamScan AI suggests that Mediheal N.M.F Aquaring Ampoule Mask REX
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
Mediheal N.M.F Aquaring Ampoule Mask REX contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, Mediheal N.M.F Aquaring Ampoule Mask REX helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
That said, there are some things about Mediheal N.M.F Aquaring Ampoule Mask REX worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycereth-26
Function:
Origin:
PEG/PPG-17/6 Copolymer
Function:
Origin:
Glycerin
Function:
Origin:
Niacinamide
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Polyglutamic Acid
Function:
Origin:
Panthenol
Function:
Origin:
Trehalose
Function:
Origin:
Betaine
Function:
Origin:
Hydroxyethyl Urea
Function:
Origin:
Rosa Centifolia Flower Water
Function:
Origin:
Fomes Officinalis (Mushroom) Extract
Function:
Origin:
Hamamelis Virginiana (Witch Hazel) Water
Function:
Origin:
Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract
Function:
Origin:
Glutamine
Function:
Origin:
Glutamic Acid
Function:
Origin:
Arginine
Function:
Origin:
Alanine
Function:
Origin:
Phenylalanine
Function:
Origin:
Portulaca Oleracea Extract
Function:
Origin:
Hydrolyzed Collagen
Function:
Origin:
Aloe Barbadensis Leaf Juice
Function:
Origin:
Beta-Glucan
Function:
Origin:
Xanthan Gum
Function:
Origin:
Butylene Glycol
Function:
Origin:
Boswellia Serrata Resin Extract
Function:
Origin:
Salix Alba (Willow) Bark Extract
Function:
Origin:
Carbomer
Function:
Origin:
Allantoin
Function:
Origin:
Polysorbate 80
Function:
Origin:
Adenosine
Function:
Origin:
Disodium EDTA
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
17.7
6
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 17.7 10
10.0
6
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 17.7 10
10
All humectants
17.7
6
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2 3
n/a
- 0.3 -
n/a
- 0.3 -
Total
3
Niacinamide
3
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2
1.5
0.3
0.3
0.3
0.3
0.3
All antioxidants 5 3 Rich in antioxidants
All antioxidants
5
Niacinamide
2
Sodium Hyaluronate
1.5
Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract
0.3
Portulaca Oleracea Extract
0.3
Aloe Barbadensis Leaf Juice
0.3
Beta-Glucan
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 4.1 5 No
All soothing
4.1
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycereth-26
Est. %6
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

PEG/PPG-17/6 Copolymer
Est. %4
Function
Origin
PEG/PPG-17/6 CopolymerA synthetic polymer that has many uses. It can help add slip by itself and also supports silicone-based ingredients in various products.
Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Niacinamide
Est. %2
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Sodium Hyaluronate
Est. %1.5
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

1,2-Hexanediol
Est. %1.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Polyglutamic Acid
Est. %1
Function
Origin
Polyglutamic AcidA natural polymer with incredible water-binding properties that is prepared from glutamic acid through fermentation.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Trehalose
Est. %0.3
Function
Origin
TrehaloseA sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Betaine
Est. %0.3
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Hydroxyethyl Urea
Est. %0.3
Function
Origin
Hydroxyethyl UreaHydroxyethyl urea is a synthetic derivative of regular urea (read about it here). This ingredient, similarly to urea, is humectant moisturizing and helps to retain more water to the skin’s surface, leaving it more moisturized. There aren't any studies that analyze the effects of this ingredient in great detail.
Rosa Centifolia Flower Water
Est. %0.3
Function
Origin
Rosa Centifolia Flower WaterRosa centifolia flower water is fragrant water that is leftover after the steam distillation of the rose petals from the Rosa centifolia – the Provence rose or cabbage rose (referring to its rich, multi-petal flower head). Read more on rose oil here: Rosa Damascena Flower oil.
Fomes Officinalis (Mushroom) Extract
Est. %0.3
Function
Origin
Fomes Officinalis (Mushroom) Extract
Hamamelis Virginiana (Witch Hazel) Water
Est. %0.3
Function
Origin
Hamamelis Virginiana (Witch Hazel) WaterA fragrant, astringent essential water obtained by steeping and distilling the twigs and leaves of the witch hazel plant. It leaves the skin feeling tight and refreshed after application and helps with the healing of small cuts on the skin.
Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract
Est. %0.3
Function
Origin
Prunus Amygdalus Dulcis (Sweet Almond) Seed ExtractSweet almond seed extract is extracted either from whole hulled sweet almonds or from the almond press cake left over after oil pressing. It contains various organic acids, flavonoids, and tannins – which provide antioxidant effects in skincare. Read more on almonds here: Prunus Amygdalus Dulcis (Sweet Almond) Oil.
Glutamine
Est. %0.3
Function
Origin
GlutamineA humectant moisturizing amino acid that, aside from attracting water to the skin’s surface, can also soothe allergic itching and reduce the signs of inflammation.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Phenylalanine
Est. %0.3
Function
Origin
PhenylalanineAn essential amino acid used in the treatment of vitiligo and other pigmentation issues. It is considered less effective than other anti-pigment ingredients and is often used in combination with them.
Portulaca Oleracea Extract
Est. %0.3
Function
Origin
Portulaca Oleracea ExtractDerived from green or common purslane, this moisturizing extract is particularly rich in alpha-linolenic acid, an omega-3 fatty acid, and contains antioxidant glutathione and vitamin E. As a herbal medicine, it is believed to treat headaches and inflammation.
Hydrolyzed Collagen
Est. %0.3
Function
Origin
Hydrolyzed Collagen

A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.

Aloe Barbadensis Leaf Juice
Est. %0.3
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Boswellia Serrata Resin Extract
Est. %0.3
Function
Origin
Boswellia Serrata Resin Extract
Salix Alba (Willow) Bark Extract
Est. %0.3
Function
Origin
Salix Alba (Willow) Bark ExtractA potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Polysorbate 80
Est. %0.3
Function
Origin
Polysorbate 80A non-ionic surfactant, which means that it contains no chemical charges. It can be used as a mild cleansing agent in skin cleansing products but is more commonly used for its emulsifying abilities.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.