MediCube AGE-R Collagen Booster Gel Serum Review

MediCube AGE-R Collagen Booster Gel Serum
5.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
3.8Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does MediCube AGE-R Collagen Booster Gel Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what MediCube AGE-R Collagen Booster Gel Serum has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.2 out of 10.
  • Modest anti-wrinkle efficacy: MediCube AGE-R Collagen Booster Gel Serum has an anti-wrinkle rating of 3.8 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

Key Benefits of MediCube AGE-R Collagen Booster Gel Serum

 
These are the key benefits you can expect from using MediCube AGE-R Collagen Booster Gel Serum:
 

Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, MediCube AGE-R Collagen Booster Gel Serum is quite moisturizing, with a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.3 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Methylpropanediol (est. ≈7.5%), Glycereth-26 (est. ≈5.0%) and Glycerin (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, MediCube AGE-R Collagen Booster Gel Serum has a modest level of anti-wrinkle efficacy, rated 3.8 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈2.5%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, MediCube AGE-R Collagen Booster Gel Serum also contains some ingredients marketed often as effective in reducing wrinkles, specifically Adenosine, Melia Azadirachta Leaf Extract, and Fucus Vesiculosus Extract. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that MediCube AGE-R Collagen Booster Gel Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.5%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of MediCube AGE-R Collagen Booster Gel Serum

 
Here’s an overview of the pros and cons of MediCube AGE-R Collagen Booster Gel Serum to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Offers modest anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage

Cons: 

  • We couldn't find any

Ingredients

Est. % Ingredient Origin Functions
65
7.5
5
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Methylpropanediol
Function:
Origin:
Glycereth-26
Function:
Origin:
Glycerin
Function:
Origin:
Niacinamide
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Polyglycerin-3
Function:
Origin:
Methyl Gluceth-20
Function:
Origin:
Methyl Gluceth-10
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Tromethamine
Function:
Origin:
Allantoin
Function:
Origin:
C12-14 Pareth-12
Function:
Origin:
Soluble Elastin
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Fragrance
Function:
Origin:
Adenosine
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Eclipta Prostrata Extract
Function:
Origin:
Butylene Glycol
Function:
Origin:
Melia Azadirachta Leaf Extract
Function:
Origin:
Soluble Collagen
Function:
Origin:
Moringa Oleifera Seed Oil
Function:
Origin:
Phosphatidylcholine
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Sodium Hyaluronate Crosspolymer
Function:
Origin:
Hydrolyzed Sodium Hyaluronate
Function:
Origin:
Hydrolyzed Hyaluronic Acid
Function:
Origin:
Sodium DNA
Function:
Origin:
Atelocollagen
Function:
Origin:
Desamido Collagen
Function:
Origin:
Ceramide NP
Function:
Origin:
Prunella Vulgaris Extract
Function:
Origin:
Fucus Vesiculosus Extract
Function:
Origin:
Hydrolyzed Collagen
Function:
Origin:
Sodium Acetylated Hyaluronate
Function:
Origin:
Hydroxypropyltrimonium Hyaluronate
Function:
Origin:
Collagen
Function:
Origin:
Collagen Amino Acids
Function:
Origin:
Glycine
Function:
Origin:
Serine
Function:
Origin:
Procollagen
Function:
Origin:
Glutamic Acid
Function:
Origin:
Lysine
Function:
Origin:
Alanine
Function:
Origin:
Threonine
Function:
Origin:
Proline
Function:
Origin:
Arginine
Function:
Origin:

Ratings

All humectants
28.1
7.5
5
3
2.5
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 28.1 10
10.0
7.5
5
3
2.5
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Humectancy
7.5
5
3
2.5
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 28.1 10
10
All humectants
28.1
7.5
5
3
2.5
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2.5 3.8
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
3.8
Niacinamide
3.8
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2.5
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Melia Azadirachta Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Fucus Vesiculosus Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3.8
Ingredient Est. % Benchmark
Rich in Antioxidants
2.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 4.6 3 Rich in antioxidants
All antioxidants
4.6
Niacinamide
2.5
Sodium Hyaluronate
0.3
Melia Azadirachta Leaf Extract
0.3
Moringa Oleifera Seed Oil
0.3
Hyaluronic Acid
0.3
Hydrolyzed Sodium Hyaluronate
0.3
Hydrolyzed Hyaluronic Acid
0.3
Prunella Vulgaris Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2.5
0.3
0.3
0.3
0.3
0.3
All soothing 4 5 No
All soothing
4
2.5
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Methylpropanediol
Est. %7.5
Function
Origin
MethylpropanediolMethylpropanediol is a unique glycol that contains two primary hydroxyl groups. That makes methylpropanediol a powerful humectant and an excellent solvent.
Glycereth-26
Est. %5
Function
Origin
Glycereth-26

A glycerin-based ingredient with humectant moisturizing properties. It is an excellent emulsifier and thickener.

Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Niacinamide
Est. %2.5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

1,2-Hexanediol
Est. %2
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Polyglycerin-3
Est. %1.5
Function
Origin
Polyglycerin-3
Methyl Gluceth-20
Est. %1.3
Function
Origin
Methyl Gluceth-20A humectant synthetically derived from glucose. It takes on the form of a clear, syrupy liquid.
Methyl Gluceth-10
Est. %1
Function
Origin
Methyl Gluceth-10A synthetic, humectant moisturizing ingredient derived from glucose.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
C12-14 Pareth-12
Est. %0.3
Function
Origin
C12-14 Pareth-12
Soluble Elastin
Est. %0.3
Function
Origin
Soluble Elastin
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Eclipta Prostrata Extract
Est. %0.3
Function
Origin
Eclipta Prostrata ExtractA soothing extract of false daisy that contains a variety of active anti-inflammatory phytochemicals such as flavonoids, terpenes, phytosterols, and special compounds called thiopenes.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Melia Azadirachta Leaf Extract
Est. %0.3
Function
Origin
Melia Azadirachta Leaf ExtractAn antimicrobial and antioxidant extract derived from Neem leaves – an Indian traditional medicine. Neem leaves have been found to possess antibacterial and antifungal activity. It is also a prospective anti-wrinkle ingredient.
Soluble Collagen
Est. %0.3
Function
Origin
Soluble CollagenA protein obtained from farm or marine animals. Collagen molecules are too big to penetrate the skin so when they are applied via a skincare product they sit on top of the skin and act as humectant moisturizers.
Moringa Oleifera Seed Oil
Est. %0.3
Function
Origin
Moringa Oleifera Seed OilAn oil obtained from the seeds of Moringa oleifera, a fast-growing bush native to Northern India and the sub-Himalayan regions. It contains mainly oleic acid, as well as many additional anti-inflammatory compounds and high levels of vitamin E.
Phosphatidylcholine
Est. %0.3
Function
Origin
PhosphatidylcholineA special emulsifying lipid used to create delivery spheres called liposomes.
Hyaluronic Acid
Est. %0.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Sodium Hyaluronate Crosspolymer
Est. %0.3
Function
Origin
Sodium Hyaluronate CrosspolymerA modified version of regular hyaluronic acid. It attracts large volumes of water, thereby making it an effective humectant moisturizing ingredient.
Hydrolyzed Sodium Hyaluronate
Est. %0.3
Function
Origin
Hydrolyzed Sodium HyaluronateA very small-molecule version of regular sodium hyaluronate. It is a powerful humectant skin-identical ingredient that absorbs into the skin and offers plumping, smoothing, and anti-wrinkle effects.
Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
Hydrolyzed Hyaluronic AcidA smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Sodium DNA
Est. %0.3
Function
Origin
Sodium DNA
Atelocollagen
Est. %0.3
Function
Origin
AtelocollagenA collagen molecule that has precisely the same properties as the regular collagen – a fantastic humectant moisturizer.
Desamido Collagen
Est. %0.3
Function
Origin
Desamido Collagen
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Prunella Vulgaris Extract
Est. %0.3
Function
Origin
Prunella Vulgaris Extract
Fucus Vesiculosus Extract
Est. %0.3
Function
Origin
Fucus Vesiculosus ExtractAn extract from a brown sea algae called bladderwrack. It was shown to increase skin elasticity in one study and boost collagen and HA production in another. Polysaccharides are able to treat irritated and dry skin.
Hydrolyzed Collagen
Est. %0.3
Function
Origin
Hydrolyzed Collagen

A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.

Sodium Acetylated Hyaluronate
Est. %0.3
Function
Origin
Sodium Acetylated HyaluronateA chemically modified version of hyaluronic acid. It is more stable and less sticky than regular HA, while still providing the same humectant moisturizing properties (according to the manufacturer). There have been no clinical studies to confirm this.
Hydroxypropyltrimonium Hyaluronate
Est. %0.3
Function
Origin
Hydroxypropyltrimonium Hyaluronate
Collagen
Est. %0.3
Function
Origin
CollagenA protein that builds all human tissues, especially skin and joints. It is used as a moisturizing humectant ingredient in skincare.
Collagen Amino Acids
Est. %0.3
Function
Origin
Collagen Amino AcidsA mixture of amino acids obtained by chopping up collagen molecules. It consists mainly of glycine, proline, alanine, and hydroxyproline. They all have humectant properties.
Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Procollagen
Est. %0.3
Function
Origin
Procollagen
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Lysine
Est. %0.3
Function
Origin
LysineA humectant moisturizing amino acid that is a part of the skin's Natural Moisturizing Factor. It is slightly alkaline and helps to balance the product's pH. It may have a slightly fishy smell.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Threonine
Est. %0.3
Function
Origin
ThreonineAn essential amino acid that may play a role in collagen production. However, more research is needed in order to confirm or deny these claims.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.