Le Mieux TGF-B Booster Review

Le Mieux TGF-B Booster
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
0.4Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does Le Mieux TGF-B Booster Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Le Mieux TGF-B Booster has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Slight anti-wrinkle effect: Le Mieux TGF-B Booster has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Antioxidant protection.

Key Benefits of Le Mieux TGF-B Booster

 
These are the key benefits you can expect from using Le Mieux TGF-B Booster:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Le Mieux TGF-B Booster is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Galactomyces Ferment Filtrate (est. ≈75.0%), Sodium Hyaluronate (est. ≈2.5%) and Hyaluronic Acid (est. ≈2.3%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, Le Mieux TGF-B Booster has a slight anti-wrinkle rating of 0.4 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈0.3%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Le Mieux TGF-B Booster also contains some ingredients often marketed as effective in reducing wrinkles, specifically Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1, Acetyl Octapeptide-3, Saccharomyces/Copper Ferment, Saccharomyces/Zinc Ferment, and Folic Acid. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Le Mieux TGF-B Booster is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈2.5%) and Hyaluronic Acid (est. ≈2.3%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Le Mieux TGF-B Booster

 
CreamScan AI identified a few things to consider before adding Le Mieux TGF-B Booster to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Le Mieux TGF-B Booster as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Le Mieux TGF-B Booster

 
Here’s an overview of the pros and cons of Le Mieux TGF-B Booster to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Provides slight anti-wrinkle efficacy
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage

Cons: 

  • Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants

Ingredients

Est. % Ingredient Origin Functions
75
2.5
2.4
2.3
2.2
2.1
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Galactomyces Ferment Filtrate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Oryza Sativa (Rice) Bran Water
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Zinc Hydrolyzed Hyaluronate
Function:
Origin:
Hydroxypropyltrimonium Hyaluronate
Function:
Origin:
Sodium Hyaluronate Dimethylsilanol
Function:
Origin:
Sodium Hyaluronate Crosspolymer
Function:
Origin:
C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate
Function:
Origin:
Hydrolyzed Hyaluronic Acid
Function:
Origin:
Sodium Acetylated Hyaluronate
Function:
Origin:
Ascorbyl Propyl Hyaluronate
Function:
Origin:
Superoxide Dismutase
Function:
Origin:
Saccharomyces Polypeptides
Function:
Origin:
Oligopeptide-5
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Palmitoyl Tripeptide-5
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Acetyl Octapeptide-3
Function:
Origin:
Ceramide NS
Function:
Origin:
Saccharomyces/Copper Ferment
Function:
Origin:
Saccharomyces/Zinc Ferment
Function:
Origin:
Saccharomyces/Manganese Ferment
Function:
Origin:
Riboflavin
Function:
Origin:
Phospholipids
Function:
Origin:
Folic Acid
Function:
Origin:
Enteromorpha Compressa Extract
Function:
Origin:
Glycoproteins
Function:
Origin:
Ginkgo Biloba Leaf Extract
Function:
Origin:
Serine
Function:
Origin:
Proline
Function:
Origin:
Alanine
Function:
Origin:
Glutamic Acid
Function:
Origin:
Niacinamide
Function:
Origin:
Sphingomonas Ferment Extract
Function:
Origin:
Sodium Phytate
Function:
Origin:
Fragrance
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Undecylenoyl Glycine
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Capryloyl Glycine
Function:
Origin:

Ratings

All humectants
88.5
75
2.5
2.3
2.2
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 88.5 10
10.0
75
2.5
2.3
2.2
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
75
2.5
2.3
2.2
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 88.5 10
10
All humectants
88.5
75
2.5
2.3
2.2
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.4
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-5
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Octapeptide-3
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Saccharomyces/Copper Ferment
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Saccharomyces/Zinc Ferment
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Folic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.4
Ingredient Est. % Benchmark
Rich in Antioxidants
2.5
2.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 6.6 3 Rich in antioxidants
All antioxidants
6.6
Sodium Hyaluronate
2.5
Hyaluronic Acid
2.3
Niacinamide
0.3
Hydrolyzed Hyaluronic Acid
0.3
Superoxide Dismutase
0.3
Riboflavin
0.3
Glycoproteins
0.3
Ginkgo Biloba Leaf Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Galactomyces Ferment Filtrate
Est. %75
Function
Origin
Galactomyces Ferment Filtrate
Sodium Hyaluronate
Est. %2.5
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Oryza Sativa (Rice) Bran Water
Est. %2.4
Function
Origin
Oryza Sativa (Rice) Bran Water
Hyaluronic Acid
Est. %2.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Zinc Hydrolyzed Hyaluronate
Est. %2.2
Function
Origin
Zinc Hydrolyzed Hyaluronate
Hydroxypropyltrimonium Hyaluronate
Est. %2.1
Function
Origin
Hydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Dimethylsilanol
Est. %2
Function
Origin
Sodium Hyaluronate Dimethylsilanol
Sodium Hyaluronate Crosspolymer
Est. %1.5
Function
Origin
Sodium Hyaluronate CrosspolymerA modified version of regular hyaluronic acid. It attracts large volumes of water, thereby making it an effective humectant moisturizing ingredient.
C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate
Est. %1
Function
Origin
C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate
Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
Hydrolyzed Hyaluronic AcidA smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Sodium Acetylated Hyaluronate
Est. %0.3
Function
Origin
Sodium Acetylated HyaluronateA chemically modified version of hyaluronic acid. It is more stable and less sticky than regular HA, while still providing the same humectant moisturizing properties (according to the manufacturer). There have been no clinical studies to confirm this.
Ascorbyl Propyl Hyaluronate
Est. %0.3
Function
Origin
Ascorbyl Propyl Hyaluronate
Superoxide Dismutase
Est. %0.3
Function
Origin
Superoxide Dismutase
Saccharomyces Polypeptides
Est. %0.3
Function
Origin
Saccharomyces Polypeptides
Oligopeptide-5
Est. %0.3
Function
Origin
Oligopeptide-5
Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Palmitoyl Tripeptide-5
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-5

A small synthetic peptide that signals the skin to produce more collagen. It has been clinically tested and proven to reduce skin roughness and the appearance of wrinkles.

Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Acetyl Octapeptide-3
Est. %0.3
Function
Origin
Acetyl Octapeptide-3

A synthetically made peptide with an effect similar to Botox - it relaxes the facial muscles and temporarily reduces the appearance of mimic wrinkles.

Ceramide NS
Est. %0.3
Function
Origin
Ceramide NSA wax-like lipid natural to the skin’s lipid matrix. It is less frequently used but, in combination with other ceramides, can help to restore balance in the skin’s lipid barrier.
Saccharomyces/Copper Ferment
Est. %0.3
Function
Origin
Saccharomyces/Copper FermentA biotech ingredient that serves to supplement copper in the skin. Copper is essential for elastin production.
Saccharomyces/Zinc Ferment
Est. %0.3
Function
Origin
Saccharomyces/Zinc FermentA biotech ingredient that serves to supplement zinc to the skin. Zinc is essential for wound healing and the activity of antioxidant enzymes.
Saccharomyces/Manganese Ferment
Est. %0.3
Function
Origin
Saccharomyces/Manganese Ferment
Riboflavin
Est. %0.3
Function
Origin
RiboflavinRiboflavin, also known as Vitamin B2, is used in skincare as a coloring agent due to its bright, brilliant orange-yellow color. The research shows that it is a good antioxidant and can protect the skin from UV-induced damage.
Phospholipids
Est. %0.3
Function
Origin
PhospholipidsA large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Folic Acid
Est. %0.3
Function
Origin
Folic AcidA critical vitamin for the body that needs more research for topical applications.
Enteromorpha Compressa Extract
Est. %0.3
Function
Origin
Enteromorpha Compressa ExtractDerived from marine seaweed Ulva compressa, the extract is rich in various soothing polysaccharides and polyphenolic compounds.
Glycoproteins
Est. %0.3
Function
Origin
GlycoproteinsA broad term indicating a specific type of proteins, most likely of animal origin.
Ginkgo Biloba Leaf Extract
Est. %0.3
Function
Origin
Ginkgo Biloba Leaf ExtractAn antioxidant, astringent and soothing extract derived from Ginkgo biloba tree leaves, a rare Chinese tree that is endangered in the wild, but grown nowadays as a decorative tree in parks. When taken orally, the extract can improve memory and brain function.
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Alanine
Est. %0.3
Function
Origin
AlanineA simple amino acid used in skincare as a humectant moisturizing ingredient. It is a part of the so-called Natural Moisturizing Factor, a complex mixture of free amino acids and other water-soluble compounds found in skin cells.
Glutamic Acid
Est. %0.3
Function
Origin
Glutamic AcidA non-essential amino acid that serves as a building block for all proteins in the body. It is a moisturizing humectant and a part of the skin's Natural Moisturizing Factor, a mixture of amino acids in skin cells that keeps them hydrated.
Niacinamide
Est. %0.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Sphingomonas Ferment Extract
Est. %0.3
Function
Origin
Sphingomonas Ferment Extract
Sodium Phytate
Est. %0.3
Function
Origin
Sodium PhytateSodium phytate is a chelating agent that serves to remove heavy metal ions from water. Removing metal ions helps other ingredients, such as antioxidants and preservatives, to perform better and keep products from separating.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Undecylenoyl Glycine
Est. %0.3
Function
Origin
Undecylenoyl Glycine
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Capryloyl Glycine
Est. %0.3
Function
Origin
Capryloyl GlycineA naturally-derived or synthetically produced multi-functional ingredient. As an anti-microbial it can act as part of a product's preservative system or reduce microbes on the skin that cause certain kinds of acne or dandruff.