La Roche-Posay Substiane Serum Review

La Roche-Posay Substiane Serum
3.6
/ 10
Moisturizing
7.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
Review

Does La Roche-Posay Substiane Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what La Roche-Posay Substiane Serum has to offer:
 
✅ Light moisturizing. It has a moisturizing rating of 3.6 out of 10.

  

Key Benefits of La Roche-Posay Substiane Serum

 
These are the key benefits you can expect from using La Roche-Posay Substiane Serum:
 

🔵 Lightweight Moisturizer Well-Suited for Oily Skin

According to CreamScan analysis, La Roche-Posay Substiane Serum is lightly moisturizing, with a moisturizing rating of 3.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a high humectancy of 7.0 out of 10, primarily due to the high content of Glycerin (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It can also be a good option for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Enhancement for Any Skincare Routine

But it’s not limited to oily skin - such a humectant enhancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of La Roche-Posay Substiane Serum

 
Here’s an overview of the pros and cons of La Roche-Posay Substiane Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing well-suited for oily skin
✅ As part of a routine: A humectant moisturizing enhancement, beneficial for any skin type
✅ Lightweight texture
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: La Roche-Posay Substiane Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that La Roche-Posay Substiane Serum
, when used alone, delivers lightweight, humectant-rich moisturizing that is well-suited for oily skin. As part of a moisturizing routine, it provides a humectant enhancement, beneficial for all skin types.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Undecane
Function:
Origin:
Hydroxypropyl Tetrahydropyrantriol
Function:
Origin:
Glycerin
Function:
Origin:
Alcohol Denat.
Function:
Origin:
Butylene Glycol
Function:
Origin:
Propylene Glycol
Function:
Origin:
Sodium Tetrahydrojasmonate
Function:
Origin:
Isopropyl Lauroyl Sarcosinate
Function:
Origin:
Poly C10-30 Alkyl Acrylate
Function:
Origin:
Dimethicone
Function:
Origin:
Cetearyl Alcohol
Function:
Origin:
Tridecane
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Stearyl Alcohol
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Dimethiconol
Function:
Origin:
Cetearyl Glucoside
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Arginine PCA
Function:
Origin:
Serine
Function:
Origin:
Poloxamer 338
Function:
Origin:
Ammonium Polyacryloyldimethyl Taurate
Function:
Origin:
Disodium EDTA
Function:
Origin:
Hydrolyzed Linseed Extract
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Acetyl Dipeptide-1 Cetyl Ester
Function:
Origin:
Xanthan Gum
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
7.0
3
1.5
1.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
3.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 7.0 10
7.0
3
1.5
1.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
3.6
Ingredient Est. % Benchmark Humectancy
3
1.5
1.3
0.3
0.3
0.3
0.3
All humectants 7.0 10
7
All humectants
7.0
3
1.5
1.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
None
Total
0
None
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
All antioxidants 0.3 3 No
All antioxidants
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
None
All soothing 0 5 No
All soothing
0
None
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Undecane
Est. %6
Function
Origin
Undecane
Hydroxypropyl Tetrahydropyrantriol
Est. %4
Function
Origin
Hydroxypropyl Tetrahydropyrantriol
Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Alcohol Denat.
Est. %2
Function
Origin
Alcohol Denat.

Denatured alcohol is ethanol that contains additives that make it unsafe to consume. It is mainly used as a solvent and an antimicrobial agent. A major drawback to alcohol denat. is that it dries out the skin.

Butylene Glycol
Est. %1.5
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Propylene Glycol
Est. %1.3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Sodium Tetrahydrojasmonate
Est. %1
Function
Origin
Sodium Tetrahydrojasmonate
Isopropyl Lauroyl Sarcosinate
Est. %0.3
Function
Origin
Isopropyl Lauroyl Sarcosinate
Poly C10-30 Alkyl Acrylate
Est. %0.3
Function
Origin
Poly C10-30 Alkyl Acrylate
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Cetearyl Alcohol
Est. %0.3
Function
Origin
Cetearyl AlcoholA blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Tridecane
Est. %0.3
Function
Origin
Tridecane
Dipropylene Glycol
Est. %0.3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Stearyl Alcohol
Est. %0.3
Function
Origin
Stearyl AlcoholA natural fatty alcohol that thickens, stabilizes, and keeps emulsions a bright white color. It has many uses, the main one being as an emulsifier. It also acts as an opacifying agent and emollient.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Dimethiconol
Est. %0.3
Function
Origin
DimethiconolA synthetic dimethicone with rich, non-tacky emolliency. It features the typical sensorial profile of silicones, with high spreadability and a luxurious, oil-free after-feel. Dimethiconol can also serve as an antifoaming agent.
Cetearyl Glucoside
Est. %0.3
Function
Origin
Cetearyl GlucosideAn emulsifier that creates stable mixtures of oil in water that feel soft and spread easily. Cetearyl glucoside is sold with cetearyl alcohol as an emulsifier blend and also provides some body to the formula.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Arginine PCA
Est. %0.3
Function
Origin
Arginine PCA
Serine
Est. %0.3
Function
Origin
SerineA non-essential amino acid, meaning that our body can produce it. It is the largest constituent of the skin's Natural Moisturizing Factor and is used in skincare as a humectant moisturizing ingredient.
Poloxamer 338
Est. %0.3
Function
Origin
Poloxamer 338
Ammonium Polyacryloyldimethyl Taurate
Est. %0.3
Function
Origin
Ammonium Polyacryloyldimethyl TaurateAn emulsion stabilizer and thickener with gelling properties. The products containing this ingredient frequently feature lightweight and refreshing aesthetics upon application to the skin.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Hydrolyzed Linseed Extract
Est. %0.3
Function
Origin
Hydrolyzed Linseed ExtractThis is an emollient derivative of linseed extract that is also rich in beneficial amino acids.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Acetyl Dipeptide-1 Cetyl Ester
Est. %0.3
Function
Origin
Acetyl Dipeptide-1 Cetyl EsterA dipeptide-based ingredient claimed to stimulate elastin production and reduce the appearacne of wrinkles and sagging skin.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.