iS Clinical Youth Serum

iS Clinical Youth Serum
3.0
/ 10
Moisturizing
6.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
$$$$

Review

Results you may expect from using iS Clinical Youth Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using iS Clinical Youth Serum:

  • Light moisturizing. It has a moisturizing rating of 3.0 out of 10.
  • Some anti-wrinkle efficacy: iS Clinical Youth Serum has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Lightly moisturizing: iS Clinical Youth Serum has a moisturizing rating of 3.0 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a high humectancy of 6.0 out of 10, primarily due to the high content of Glycerin (est. ≈3.0%).

Tip: Studies suggest that humectants alone do not moisturize the skin. We recommend applying a product with some occlusive ingredients after the use of this one.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, iS Clinical Youth Serum has a slight anti-wrinkle rating of 3.0 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Asiaticoside (est. ≈0.3%), 
 derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy confirmed by one study.
 
Among others, iS Clinical Youth Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically Caffeine, Pseudoalteromonas Ferment Extract, Tripeptide-10 Citrulline, Tripeptide-1, Haberlea Rhodopensis Leaf Extract, Retinyl Palmitate, Ascorbyl Palmitate, Asiatic Acid, and some others. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that iS Clinical Youth Serum is rich (> 3%) in antioxidants, specifically Caffeine (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
6.0
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
3.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 6.0 10
6.0
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
3.0
Ingredient Est. % Benchmark Humectancy
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 6.0 10
6
All humectants
6.0
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
3 /10 0.1 0.3 3
n/a
- 4 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
3
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
0.3
Caffeine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
4
Pseudoalteromonas Ferment Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tripeptide-10 Citrulline
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Haberlea Rhodopensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ascorbyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Asiatic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Madecassic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
4
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.5 3 Rich in antioxidants
All antioxidants
5.5
Caffeine
4
Asiaticoside
0.3
Beta Vulgaris (Beet) Root Extract
0.3
Ergothioneine
0.3
Tocopheryl Acetate
0.3
Ascorbyl Palmitate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
PVP
Est. %6
Function
Origin
An excellent film-former used in hairsprays, peel-off masks, and even some self-tanning products. These films are strong and hold onto the skin.
Caffeine
Est. %4
Function
Origin
An antioxidant compound that is obtained from coffee and tea leaves. It increases the microcirculation of blood in the skin and is claimed to be able to reduce the appearance of orange peel skin (although the research is lacking).
Glycerin
Est. %3
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Hydroxyethylcellulose
Est. %0.3
Function
Origin
A naturally-derived thickener that can form clear gel textures without the slimy feeling, unlike some other natural gel-formers.
Ceratonia Siliqua (Carob) Gum
Est. %0.3
Function
Origin
Also known as carob gum, this ingredient is a plant-based formula helper extracted from carob tree seeds. It consists of film- and gel-forming polysaccharides called galactomannans.
Hydrolyzed Casein
Est. %0.3
Function
Origin
Description is coming soon
Pseudoalteromonas Ferment Extract
Est. %0.3
Function
Origin
An ingredient obtained from a bacterial culture. According to the patent holder, it produces a special glycoprotein that promotes collagen and elastin synthesis and moisturizes the skin by drawing water to it.
Hydrolyzed Wheat Protein
Est. %0.3
Function
Origin
Wheat protein broken down into its individual amino acids. It is commonly used as a film-former and antistatic agent.
Hydrolyzed Soy Protein
Est. %0.3
Function
Origin
A mixture of proteins obtained from soybeans. It can have many different functions depending on the manufacturer, although it is most commonly used in skincare products as a humectant moisturizing ingredient.
Tripeptide-10 Citrulline
Est. %0.3
Function
Origin
A synthetically made peptide that controls the proper formation of collagen strands in the skin. It was tested in a clinical trial and showed increased skin flexibility and collagen-repair activity.
Tripeptide-1
Est. %0.3
Function
Origin

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.

Lecithin
Est. %0.3
Function
Origin
A humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Carbomer
Est. %0.3
Function
Origin
A synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Triethanolamine
Est. %0.3
Function
Origin
A clear, colorless, and highly viscous liquid, this ingredient is an excellent pH adjuster. When it is necessary to neutralize an acidic solution or to generally increase the pH of a product, triethanolamine is a common choice.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ahnfeltiopsis Concinna Extract
Est. %0.3
Function
Origin
Description is coming soon
Beta Vulgaris (Beet) Root Extract
Est. %0.3
Function
Origin
A purple-red extract with antioxidant activity that is obtained from red beetroot.
Haberlea Rhodopensis Leaf Extract
Est. %0.3
Function
Origin
A prospective anti-wrinkle extract derived from a rare plant – the Orpheus flower. Studies have shown that it increases skin elasticity and promotes collagen production. It also contains moisturizing polysaccharides.
Yeast Extract
Est. %0.3
Function
Origin
Also labeled as faex extract, this is a natural ingredient derived from fresh yeast. It is used in skincare as a humectant. Yeast extract also helps to shield injured or exposed skin and can aid in the skin’s wound healing process.
Acetyl Tyrosine
Est. %0.3
Function
Origin
Acetyl tyrosine is a derivative of the amino acid tyrosine. It is used as a tanning agent in skincare, helping pigment cells (melanosomes) to produce more dark skin pigment.
Proline
Est. %0.3
Function
Origin
The best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Hydrolyzed Vegetable Protein
Est. %0.3
Function
Origin
A blanket term used for plant-based proteins that have been processed into smaller chunks. They add to the skincare product's film-forming and water-binding properties.
Adenosine Triphosphate
Est. %0.3
Function
Origin
A cellular energy source that is thought to revitalize skin cells.
Ergothioneine
Est. %0.3
Function
Origin
A naturally-occurring amino acid that functions as a powerful and versatile antioxidant.
Saccharide Isomerate
Est. %0.3
Function
Origin
A naturally-derived humectant that provides moisturization at low levels and is less sticky than other humectants like glycerin.
Hydrolyzed Wheat Protein/PVP Crosspolymer
Est. %0.3
Function
Origin
Description is coming soon
VP/Dimethylaminoethylmethacrylate Copolymer
Est. %0.3
Function
Origin
Description is coming soon
Phospholipids
Est. %0.3
Function
Origin
A large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Tocopheryl Acetate
Est. %0.3
Function
Origin
An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.
Retinyl Palmitate
Est. %0.3
Function
Origin
An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Ascorbyl Palmitate
Est. %0.3
Function
Origin
A form of vitamin C derived from ascorbic acid and palmitic acid. It is more stable and less irritating than ascorbic acid. Unfortunately, Ascorbyl Palmitate lacks the studies to prove its anti-wrinkle efficacy.
Asiaticoside
Est. %0.3
Function
Origin

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Asiatic Acid
Est. %0.3
Function
Origin
A compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process.
Madecassic Acid
Est. %0.3
Function
Origin
An isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns.
1,2-Hexanediol
Est. %0.3
Function
Origin
A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.