iS Clinical Extreme Protect SPF 30 Review

iS Clinical Extreme Protect SPF 30
1.1
/ 10
Moisturizing
0.6 Humectancy icon Humectancy
1.6 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
30
SPF icon
SPF
Ingredients

iS Clinical Extreme Protect SPF 30 Ingredients

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Full Ingredient List (INCI):

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Water, Octinoxate, Zinc Oxide, Polyacrylamide, Tocopherol, Ethylhexyl Palmitate, PPG-3 Myristyl Ether, Cetyl Alcohol, Glycol Stearate SE, VP/Hexadecene Copolymer, Olea Europaea (Olive) Leaf Extract, Aloe Barbadensis Leaf Juice, Asiaticoside, Asiatic Acid, Madecassic Acid, Potassium Cetyl Phosphate, Hydrogenated Palm Glycerides, Ethyl Linoleate, Oleyl Alcohol, Glyceryl Stearate, Octyldodecyl Neopentanoate, Caprylyl Glycol, Hexylene Glycol, PEG-100 Stearate, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol
Review

Does iS Clinical Extreme Protect SPF 30 Work?

 
According to CreamScan's analysis of the ingredient list, here’s what iS Clinical Extreme Protect SPF 30 has to offer:
 
✅ A bit of moisturizing. It has a moisturizing rating of 1.1 out of 10.
✅ Modest anti-wrinkle efficacy: iS Clinical Extreme Protect SPF 30 has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection
✅ Moderate to high sun protection for daily outdoor activities.

  

Key Benefits of iS Clinical Extreme Protect SPF 30

 
These are the key benefits you can expect from using iS Clinical Extreme Protect SPF 30:
 

🔵 Slight Moisturizing When Used Alone

According to CreamScan analysis, iS Clinical Extreme Protect SPF 30 is slightly moisturizing, with a moisturizing rating of 1.1 out of 10.

Is it more humectant or occlusive? This product has relatively comparable levels of Humectancy and Occlusivity: a low Humectancy of 0.6 out of 10 and a low Occlusivity of 1.6 out of 10.

This type of product provides relatively light moisturizing on its own but can contribute to overall moisturizing efficacy when used as part of a skincare routine, alongside another moisturizer.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, iS Clinical Extreme Protect SPF 30 has a modest level of anti-wrinkle efficacy, rated 3.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Asiaticoside (est. ≈0.3%),
 derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy, as confirmed by a single clinical study involving 27 participants (Lee et al.). This study demonstrated that a cream containing 0.1% asiaticoside reduced the average wrinkle depth by 8% after 12 weeks of use, compared to a vehicle (the same formulation without asiaticoside).
 
Among others, iS Clinical Extreme Protect SPF 30 also contains some ingredients marketed often as effective in reducing wrinkles, specifically Olea Europaea (Olive) Leaf Extract, Asiatic Acid, and Madecassic Acid. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that iS Clinical Extreme Protect SPF 30 is rich (> 3%) in antioxidants, specifically Tocopherol (est. ≈2.9%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

☀️☀️ Moderate to High Sun Protection for Daily Outdoor Activities

With an SPF of 30, iS Clinical Extreme Protect SPF 30 provides moderate to high sun protection, making it suitable for daily use during moderate sun exposure, such as commuting or light outdoor activities.

This level of SPF offers excellent defense against UVB rays, blocking up to 97% of harmful radiation. When labeled as broad-spectrum, these products also protect against UVA rays, which are responsible for skin aging and hyperpigmentation.

📌 For optimal protection, choose products labeled broad-spectrum to ensure defense against both UVA rays, which contribute to skin aging and pigmentation, and UVB rays that cause sunburn.

This level of SPF works well for skin types mildly prone to sunburn. It is particularly suitable for low-to-moderate UV index environments and non-tropical climates. However, it is not recommended for prolonged outdoor exposure or intense UV conditions. Reapplication every two hours is essential to maintain effectiveness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: iS Clinical Extreme Protect SPF 30

 
CreamScan identified a few things to consider before adding iS Clinical Extreme Protect SPF 30 to your skincare routine:
 

⚠️ As a Standalone Moisturizer, It Has Relatively Low Moisturizing Potential

If you use iS Clinical Extreme Protect SPF 30 for moisturizing purposes, please keep in mind that it provides relatively light moisturizing on its own, and, more importantly, it’s not optimal for any skin type.

On one hand, it has low occlusivity, which suits oily and combination skin. On the other hand, it has a low estimated concentration of humectants, which are essential for effective moisturizing of all skin types, including oily skin.

Therefore, if used as a standalone moisturizer, this product should be paired with a humectant-rich moisturizer for optimal skin hydration.

Pros & Cons of iS Clinical Extreme Protect SPF 30

 
Here’s an overview of the pros and cons of iS Clinical Extreme Protect SPF 30 to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

Provides relatively light moisturizing on its own but can contribute to the moisturizing efficacy of any skincare routine
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
Provides moderate to high sun protection, suitable for light outdoor activities in non-tropical climates
 

⭕ Cons: 

⚠️ Minimal moisturizing efficacy, even for oily skin - something to keep in mind if this is the only moisturizer in your routine
   

Summary: iS Clinical Extreme Protect SPF 30

 
Based on the ingredient list analysis, CreamScan AI suggests that iS Clinical Extreme Protect SPF 30
, as a moisturizer, provides relatively light hydration on its own but can enhance the moisturizing efficacy of any skincare routine.
 
iS Clinical Extreme Protect SPF 30 contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, iS Clinical Extreme Protect SPF 30 helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
With an SPF of 30, iS Clinical Extreme Protect SPF 30 offers moderate to high sun protection, appropriate for light outdoor activities in non-tropical climates.
 
That said, there are some things about iS Clinical Extreme Protect SPF 30 worth noting.
 
If you use iS Clinical Extreme Protect SPF 30 as your primary moisturizer, please keep in mind that it provides only light hydration, which isn’t actually ideal for any skin type. While its low occlusivity may work for oily and combination skin, it lacks sufficient humectants, which are vital for effective hydration of any skin type. Therefore, for optimal moisturizing results, it should be paired with a humectant-rich moisturizer.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
70
5.5 ,
4.1 , , , ,
3
2.9 , , , , ,
2.5 , , , ,
2 ,
1.5 , , ,
1.3
1
0.3 , , ,
0.3 , , ,
0.3 , ,
0.3 , ,
0.3 ,
0.3 , ,
0.3 , , ,
0.3 , ,
0.3 , , ,
0.3 , , ,
0.3
0.3 , , ,
0.3 ,
0.3 ,
0.3 ,
0.3 ,
0.3 ,
Est. %
Water
Function:
Origin:
Octinoxate
Function:
Origin:
Zinc Oxide
Function:
Origin:
Polyacrylamide
Function:
Origin:
Tocopherol
Function:
Origin:
Ethylhexyl Palmitate
Function:
Origin:
PPG-3 Myristyl Ether
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Glycol Stearate SE
Function:
Origin:
VP/Hexadecene Copolymer
Function:
Origin:
Olea Europaea (Olive) Leaf Extract
Function:
Origin:
Aloe Barbadensis Leaf Juice
Function:
Origin:
Asiaticoside
Function:
Origin:
Asiatic Acid
Function:
Origin:
Madecassic Acid
Function:
Origin:
Potassium Cetyl Phosphate
Function:
Origin:
Hydrogenated Palm Glycerides
Function:
Origin:
Ethyl Linoleate
Function:
Origin:
Oleyl Alcohol
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Octyldodecyl Neopentanoate
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Hexylene Glycol
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
C13-14 Isoparaffin
Function:
Origin:
Laureth-7
Function:
Origin:
Phenoxyethanol
Function:
Origin:

Ratings

All humectants
0.6
0.3
0.3
Benchmark
10
All occlusives
3.2
2.9
0.3
Benchmark
20
Moisturizing rating
1.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 0.6 10
0.6
0.3
0.3
Occlusivity All occlusives 3.2 20
1.6
2.9
0.3
Moisturizing rating
1.1
Ingredient Est. % Benchmark Humectancy
0.3
0.3
All humectants 0.6 10
0.6
All humectants
0.6
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2.9
0.3
All occlusives 3.2 20
1.6
All occlusives
3.2
2.9
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
3 /10 0.1 0.3 3
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
3
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
0.3
Olea Europaea (Olive) Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Asiatic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Madecassic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
2.9
0.3
0.3
0.3
All antioxidants 3.8 3 Rich in antioxidants
All antioxidants
3.8
Tocopherol
2.9
Asiaticoside
0.3
Olea Europaea (Olive) Leaf Extract
0.3
Aloe Barbadensis Leaf Juice
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Octinoxate
Est. %5.5
Function
Origin
OctinoxateA chemical sunscreen also known as ethylhexyl methoxycinnamate. It protects against UVB, which causes the skin to burn and tan and can lead to certain types of skin cancers. For broad-spectrum protection claims, octinoxate should be paired with a UVA sunscreen.
Zinc Oxide
Est. %4.1
Function
Origin
Zinc OxideA white mineral powder mainly used in skincare as a physical sunscreen. It protects against UVA light that leads to visible signs of aging, including wrinkles and fine lines. Zinc oxide can also be used as a colorant to enhance the whiteness of a product.
Polyacrylamide
Est. %3
Function
Origin
PolyacrylamideA synthetic ingredient that can thicken products instantly while still keeping them light and often gel-like.
Tocopherol
Est. %2.9
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Ethylhexyl Palmitate
Est. %2.5
Function
Origin
Ethylhexyl PalmitateA rich emollient without the oily after-feel, making it a popular replacement for mineral oil. It is derived from natural sources such as palm oil and palm kernel oil. Ethylhexyl palmitate is listed as a common comedogenic ingredient by acne.org.
PPG-3 Myristyl Ether
Est. %2
Function
Origin
PPG-3 Myristyl Ether
Cetyl Alcohol
Est. %1.5
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Glycol Stearate SE
Est. %1.3
Function
Origin
Glycol Stearate SE
VP/Hexadecene Copolymer
Est. %1
Function
Origin
VP/Hexadecene Copolymer
Olea Europaea (Olive) Leaf Extract
Est. %0.3
Function
Origin
Olea Europaea (Olive) Leaf ExtractAn antioxidant and fragrant extract from the leaves of the olive tree. It contains a promising anti-aging compound called Oleuropein, and a prospective anti-pigment compound called Cornoside.
Aloe Barbadensis Leaf Juice
Est. %0.3
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Asiaticoside
Est. %0.3
Function
Origin
Asiaticoside

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Asiatic Acid
Est. %0.3
Function
Origin
Asiatic AcidA compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process.
Madecassic Acid
Est. %0.3
Function
Origin
Madecassic AcidAn isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns.
Potassium Cetyl Phosphate
Est. %0.3
Function
Origin
Potassium Cetyl PhosphateA powerful emulsifier that can even mix particularly problematic water and oil blends. It is also a surfactant perfect for cleansing products that effectively rinse off oil and dirt particles from the surface of the skin.
Hydrogenated Palm Glycerides
Est. %0.3
Function
Origin
Hydrogenated Palm GlyceridesAn occlusive ingredient that can be used as a replacement for petrolatum/petroleum jelly. This locks in moisture and prevents TEWL.
Ethyl Linoleate
Est. %0.3
Function
Origin
Ethyl Linoleate
Oleyl Alcohol
Est. %0.3
Function
Origin
Oleyl Alcohol
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Octyldodecyl Neopentanoate
Est. %0.3
Function
Origin
Octyldodecyl NeopentanoateA synthetic emollient ester. This clear, colorless liquid has a unique sensorial profile that is light and silky, with good lubricity.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
PEG-100 Stearate
Est. %0.3
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
C13-14 Isoparaffin
Est. %0.3
Function
Origin
C13-14 IsoparaffinA lightweight petroleum derivative. It is a very thin liquid that functions as an emollient and a solvent for other liquids (such as thicker oils or silicones).
Laureth-7
Est. %0.3
Function
Origin
Laureth-7A mild but effective functional ingredient. It can emulsify (efficiently mix water and oil) without needing too much in a formula.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.