Derma XP Acne Spot Gel

Derma XP Acne Spot Gel
4.4
/ 10
Moisturizing
8.7 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
6.8Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Results you may expect from using Derma XP Acne Spot Gel:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Derma XP Acne Spot Gel:

  • Moderate moisturizing. It has a moisturizing rating of 4.4 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.8 out of 10, Derma XP Acne Spot Gel is effective in minimizing wrinkles.
  • Soothing: Derma XP Acne Spot Gel contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Derma XP Acne Spot Gel has a moisturizing rating of 4.4 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a very high humectancy of 8.7 out of 10, primarily due to the high content of Propylene Glycol (est. ≈5.0%) and Niacinamide (est. ≈2.5%).

Tip: Studies suggest that humectants alone do not moisturize the skin. We recommend applying a product with some occlusive ingredients after the use of this one.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Derma XP Acne Spot Gel has a high anti-wrinkle rating of 6.8 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Niacinamide (est. ≈2.5%),
     one of the most effective and well-researched anti-wrinkle ingredients.
  • Asiaticoside (est. ≈0.3%),
     derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy confirmed by one study.
Among others, Derma XP Acne Spot Gel also contains contains Madecassic Acid and Asiatic Acid, two ingredients marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Derma XP Acne Spot Gel is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈2.5%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Derma XP Acne Spot Gel is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈2.5%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
70
Water
7.5
Alcohol Denat.
5
Propylene Glycol
3
2-Hydroxyethyl Acrylate
2.5
Niacinamide
2
Sulfur
1.5
Zinc Gluconate
1.3
Salicylic Acid
1
Succinic Acid
0.3
Sodium Hydroxide
0.3
Panthenol
0.3
Dipotassium Glycyrrhizate
0.3
Phenoxyethanol
0.3
Sorbitan Isostearate
0.3
Polysorbate 60
0.3
o-Cymen-5-ol
0.3
Allantoin
0.3
Hydrolyzed Royal Jelly Protein
0.3
Ethylhexylglycerin
0.3
Disodium EDTA
0.3
Asiaticoside
0.3
Madecassic Acid
0.3
Asiatic Acid
Est. %
Water
Function:
Origin:
Alcohol Denat.
Function:
Origin:
Propylene Glycol
Function:
Origin:
2-Hydroxyethyl Acrylate
Function:
Origin:
Niacinamide
Function:
Origin:
Sulfur
Function:
Origin:
Zinc Gluconate
Function:
Origin:
Salicylic Acid
Function:
Origin:
Succinic Acid
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Panthenol
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Polysorbate 60
Function:
Origin:
o-Cymen-5-ol
Function:
Origin:
Allantoin
Function:
Origin:
Hydrolyzed Royal Jelly Protein
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Disodium EDTA
Function:
Origin:
Asiaticoside
Function:
Origin:
Madecassic Acid
Function:
Origin:
Asiatic Acid
Function:
Origin:

Ratings

All humectants
8.7
5
2.5
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
4.4
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 8.7 10
8.7
5
2.5
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
4.4
Ingredient Est. % Benchmark Humectancy
5
2.5
0.3
0.3
0.3
0.3
All humectants 8.7 10
8.7
All humectants
8.7
5
2.5
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 2.5 3.8
3 /10 0.1 0.3 3
n/a
- 0.3 -
n/a
- 0.3 -
Total
6.8
Niacinamide
3.8
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
2.5
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
0.3
Madecassic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Asiatic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6.8
Ingredient Est. % Benchmark
Rich in Antioxidants
2.5
0.3
0.3
All antioxidants 3.1 3 Rich in antioxidants
All antioxidants
3.1
Niacinamide
2.5
Asiaticoside
0.3
o-Cymen-5-ol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
2.5
1.5
1.3
0.3
0.3
0.3
All soothing 6.2 5 Rich in soothing
All soothing
6.2
2.5
1.5
1.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Alcohol Denat.
Est. %7.5
Function
Origin
Alcohol Denat.

Denatured alcohol is ethanol that contains additives that make it unsafe to consume. It is mainly used as a solvent and an antimicrobial agent. A major drawback to alcohol denat. is that it dries out the skin.

Propylene Glycol
Est. %5
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
2-Hydroxyethyl Acrylate
Est. %3
Function
Origin
2-Hydroxyethyl AcrylateDescription is coming soon
Niacinamide
Est. %2.5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Sulfur
Est. %2
Function
Origin
SulfurSulfur is a registered OTC drug ingredient that can be used to fight acne. As a keratolytic, it helps remove dead skin buildup.
Zinc Gluconate
Est. %1.5
Function
Origin
Zinc GluconateOne of the most commonly used ingredients in anti-acne products. It is an organic salt of zinc that helps to combat microbial infections, soothes and heals inflamed pimples, and regulates hormones in the skin.
Salicylic Acid
Est. %1.3
Function
Origin
Salicylic AcidThis effective peeling and anti-inflammatory BHA is used as an anti-acne agent and works by breaking down the junctions between dead skin cells. This results in the peeling of dead skin and the unclogging of pores.
Succinic Acid
Est. %1
Function
Origin
Succinic AcidDescription is coming soon
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
o-Cymen-5-ol
Est. %0.3
Function
Origin
o-Cymen-5-olA preservative related to chemicals found in the herb thyme. It has its own unique smell but is very effective even at small amounts.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Hydrolyzed Royal Jelly Protein
Est. %0.3
Function
Origin
Hydrolyzed Royal Jelly ProteinDescription is coming soon
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Asiaticoside
Est. %0.3
Function
Origin
Asiaticoside

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Madecassic Acid
Est. %0.3
Function
Origin
Madecassic AcidAn isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns.
Asiatic Acid
Est. %0.3
Function
Origin
Asiatic AcidA compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process.