Derma Factory Retinal 300ppm Cream

Derma Factory Retinal 300ppm Cream
6.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
2.2 Occlusivity icon Occlusivity
9.6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Results you may expect from using Derma Factory Retinal 300ppm Cream:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Derma Factory Retinal 300ppm Cream:

  • Significant moisturizing. It has a moisturizing rating of 6.1 out of 10.
  • Potent anti-wrinkle effect. With an anti-wrinkle rating of 9.6 out of 10, Derma Factory Retinal 300ppm Cream is highly potent in reducing wrinkles.
  • Soothing: Derma Factory Retinal 300ppm Cream contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Highly moisturizing: Derma Factory Retinal 300ppm Cream has a moisturizing rating of 6.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 2.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%), Niacinamide (est. ≈3.0%) and Panthenol (est. ≈2.5%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Derma Factory Retinal 300ppm Cream has a very high anti-wrinkle rating of 9.6 out of 10.

It contains 3 active ingredients with proven anti-wrinkle efficacy:

  • Retinal (est. ≈0.05%),
     also known as retinaldehyde, a potent ingredient of the retinoid group, with confirmed anti-wrinkle capabilities.
  • Niacinamide (est. ≈3.0%),
     one of the most effective and well-researched anti-wrinkle ingredients.
  • Ascorbic Acid (est. ≈0.3%),
     or Vitamin C, a popular anti-wrinkle ingredient, yet with average efficacy confirmed by only one study.
Among others, Derma Factory Retinal 300ppm Cream also contains contains Centella Asiatica Extract and Adenosine, two ingredients marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Derma Factory Retinal 300ppm Cream is rich (> 3%) in antioxidants, specifically Centella Asiatica Extract (est. ≈65.0%) and Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, Derma Factory Retinal 300ppm Cream is rich (> 5%) in soothing ingredients, particularly Centella Asiatica Extract (est. ≈65.0%), Niacinamide (est. ≈3.0%) and Panthenol (est. ≈2.5%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
65
Centella Asiatica Extract
9
Glycerin
6
Hydrogenated Polydecene
4
Caprylyl Methicone
3
Niacinamide
2.5
Panthenol
2
Pentylene Glycol
1.5
Polyglyceryl-3 Behenate
1.3
Water
1
1,2-Hexanediol
0.3
Ammonium Acryloyldimethyltaurate/VP Copolymer
0.3
Butylene Glycol
0.3
Polymethylsilsesquioxane
0.3
Caprylic/Capric Triglyceride
0.3
Rosin Acrylate
0.3
HEMA
0.3
Lecithin
0.3
Tromethamine
0.3
Fragrance
0.3
Ethylhexylglycerin
0.3
Xanthan Gum
0.3
Adenosine
0.05
Retinal
0.3
Disodium EDTA
0.3
Sorbitan Isostearate
0.3
Oryza Sativa (Rice) Extract
0.3
Ascorbic Acid
Est. %
Centella Asiatica Extract
Function:
Origin:
Glycerin
Function:
Origin:
Hydrogenated Polydecene
Function:
Origin:
Caprylyl Methicone
Function:
Origin:
Niacinamide
Function:
Origin:
Panthenol
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Polyglyceryl-3 Behenate
Function:
Origin:
Water
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Ammonium Acryloyldimethyltaurate/VP Copolymer
Function:
Origin:
Butylene Glycol
Function:
Origin:
Polymethylsilsesquioxane
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Rosin Acrylate
Function:
Origin:
HEMA
Function:
Origin:
Lecithin
Function:
Origin:
Tromethamine
Function:
Origin:
Fragrance
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Xanthan Gum
Function:
Origin:
Adenosine
Function:
Origin:
Retinal
Function:
Origin:
Disodium EDTA
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Oryza Sativa (Rice) Extract
Function:
Origin:
Ascorbic Acid
Function:
Origin:

Ratings

All humectants
17.4
9
3
2.5
2
0.3
0.3
0.3
Benchmark
10
All occlusives
4.3
4.0
0.3
Benchmark
20
Moisturizing rating
6.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 17.4 10
10.0
9
3
2.5
2
0.3
0.3
0.3
Occlusivity All occlusives 4.3 20
2.2
4.0
0.3
Moisturizing rating
6.1
Ingredient Est. % Benchmark Humectancy
9
3
2.5
2
0.3
0.3
0.3
All humectants 17.4 10
10
All humectants
17.4
9
3
2.5
2
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
0.3
All occlusives 4.3 20
2.2
All occlusives
4.3
4.0
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
5 /10 0.05 0.05 5
6 /10 4 3 4.5
2.5 /10 5 0.3 0.1
n/a
- 65 -
n/a
- 0.3 -
Total
9.6
Retinal
5
Ingredient anti-wrinkle power
5 /10
when present at, %
0.05
in this formula, est. %
0.05
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
65
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
9.6
Ingredient Est. % Benchmark
Rich in Antioxidants
65
3
0.3
All antioxidants 68.3 3 Rich in antioxidants
All antioxidants
68.3
Centella Asiatica Extract
65
Niacinamide
3
Ascorbic Acid
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
65
3
2.5
All soothing 70.5 5 Rich in soothing
All soothing
70.5
65
3
2.5
Benchmark
5

Ingredients explained

Centella Asiatica Extract
Est. %65
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Glycerin
Est. %9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Hydrogenated Polydecene
Est. %6
Function
Origin
Hydrogenated PolydeceneA clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
Caprylyl Methicone
Est. %4
Function
Origin
Caprylyl MethiconeA liquid silicone with occlusive moisturizing properties. Being compatible with natural oils is a challenge for most silicones, but caprylyl methicone plays well with all types of oils.
Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Panthenol
Est. %2.5
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Pentylene Glycol
Est. %2
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Polyglyceryl-3 Behenate
Est. %1.5
Function
Origin
Polyglyceryl-3 Behenate
Water
Est. %1.3
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
1,2-Hexanediol
Est. %1
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Ammonium Acryloyldimethyltaurate/VP Copolymer
Est. %0.3
Function
Origin
Ammonium Acryloyldimethyltaurate/VP CopolymerA polymeric ingredient that creates lightweight and refreshing gel textures. It also works as a viscosity controlling agent.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Polymethylsilsesquioxane
Est. %0.3
Function
Origin
PolymethylsilsesquioxaneA type of spherical powder that functions on a ball-bearing effect in which the tiny microspheres roll around on the skin and create lubricity. Polymethylsilsesquioxane offers extra slip to skincare products and makes the skin feel soft and smooth.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Rosin Acrylate
Est. %0.3
Function
Origin
Rosin Acrylate
HEMA
Est. %0.3
Function
Origin
HEMA
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Retinal
Est. %0.05
Function
Origin
Retinal

A potent ingredient of the retinoid group with confirmed anti-wrinkle capabilities.

Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Oryza Sativa (Rice) Extract
Est. %0.3
Function
Origin
Oryza Sativa (Rice) ExtractAn abrasive rice extract rich in various emollient fatty acids, amino acids, and vitamin E.
Ascorbic Acid
Est. %0.3
Function
Origin
Ascorbic Acid

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.