Derm Institute Cellular Rejuvenating Serum

Derm Institute Cellular Rejuvenating Serum
5.3
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
0.1Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
$$$$

Review

Results you may expect from using Derm Institute Cellular Rejuvenating Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Derm Institute Cellular Rejuvenating Serum:

  • Moderate moisturizing. It has a moisturizing rating of 5.3 out of 10.
  • Little anti-wrinkle effect: Derm Institute Cellular Rejuvenating Serum has an anti-wrinkle rating of 0.1 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: Derm Institute Cellular Rejuvenating Serum has a moisturizing rating of 5.3 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈4.0%), Methyl Gluceth-20 (est. ≈3.0%) and Saccharide Isomerate (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Derm Institute Cellular Rejuvenating Serum has a minimal anti-wrinkle rating of 0.1 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Ascorbic Acid (est. ≈0.3%),
 or Vitamin C, a popular anti-wrinkle ingredient, yet with average efficacy confirmed by only one study.
 
Among others, Derm Institute Cellular Rejuvenating Serum also contains some ingredients marketed as effective in reducing wrinkles, specifically Trifluoroacetyl Tripeptide-2, Ubiquinone, and Retinyl Palmitate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Derm Institute Cellular Rejuvenating Serum is rich (> 3%) in antioxidants, specifically Nelumbo Nucifera Seed Extract (est. ≈6.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
10.5
4
3
2
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.3
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.5 10
10.0
4
3
2
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.2 20
0.6
0.3
0.3
0.3
0.3
Moisturizing rating
5.3
Ingredient Est. % Benchmark Humectancy
4
3
2
0.3
0.3
0.3
0.3
0.3
All humectants 10.5 10
10
All humectants
10.5
4
3
2
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
All occlusives 1.2 20
0.6
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.1
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Trifluoroacetyl Tripeptide-2
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ubiquinone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.1
Ingredient Est. % Benchmark
Rich in Antioxidants
6
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 10.2 3 Rich in antioxidants
All antioxidants
10.2
Nelumbo Nucifera Seed Extract
6
Ascorbic Acid
0.3
Solanum Lycopersicum (Tomato) Fruit Extract
0.3
Superoxide Dismutase
0.3
Ergothioneine
0.3
Ubiquinone
0.3
Algae Extract
0.3
Ascophyllum Nodosum Extract
0.3
Carnosine
0.3
Vitis Vinifera (Grape) Seed Extract
0.3
Resveratrol
0.3
Tocopherol
0.3
Astaxanthin
0.3
Vaccinium Macrocarpon (Cranberry) Seed Oil
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Nelumbo Nucifera Seed Extract
Est. %6
Function
Origin
Description is coming soon
Glycerin
Est. %4
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Methyl Gluceth-20
Est. %3
Function
Origin
A humectant synthetically derived from glucose. It takes on the form of a clear, syrupy liquid.
Saccharide Isomerate
Est. %2
Function
Origin
A naturally-derived humectant that provides moisturization at low levels and is less sticky than other humectants like glycerin.
Dextran
Est. %1.5
Function
Origin
A naturally derived sucrose metabolite that thickens water and bulks emulsions.
Trifluoroacetyl Tripeptide-2
Est. %0.3
Function
Origin

A synthetically made peptide that was shown to slow down the degradation of elastin in the skin. It is said to be able to reduce sagging and wrinkles in different parts of the face, although this has not been well researched yet.

Sorbitan Laurate
Est. %0.3
Function
Origin
Sorbitan laurate is a sugar-based emulsifier similar to sucrose palmitate. It keeps oil broken into small droplets throughout water because of its chemical shape and nature (this is how most oil-in-water emulsifiers work by the way). These kinds of emulsifiers are mild enough to even be used in food preparations.
Acetyl Dipeptide-1 Cetyl Ester
Est. %0.3
Function
Origin
A dipeptide-based ingredient claimed to stimulate elastin production and reduce the appearacne of wrinkles and sagging skin.
Propanediol
Est. %0.3
Function
Origin
An excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Ornithine
Est. %0.3
Function
Origin
An amino acid that is claimed to be able to restore the adipose tissue in the skin, thereby making it look plumper and filled out. This has not been proven by studies as of yet.
Phospholipids
Est. %0.3
Function
Origin
A large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Glycolipids
Est. %0.3
Function
Origin
Various lipids combined with one or more sugars. It can be used as an emulsifier or a very gentle cleanser.
Hydrolyzed Collagen
Est. %0.3
Function
Origin
A humectant, film-forming, and emollient mixture of various proteins and peptides that were created by cutting the huge molecules of normal collagen into smaller pieces for better absorption. It also has some antioxidant properties.
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %0.3
Function
Origin
A multi-functional ingredient that forms a polymeric network, thereby thickening the formula and preventing other ingredients from shifting around.
Hydrogenated Polydecene
Est. %0.3
Function
Origin
A clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
Laureth-8
Est. %0.3
Function
Origin
Description is coming soon
Hydrolyzed Soy Flour
Est. %0.3
Function
Origin
Description is coming soon
Polydecene
Est. %0.3
Function
Origin
Description is coming soon
Solanum Lycopersicum (Tomato) Fruit Extract
Est. %0.3
Function
Origin
A bright red extract obtained from tomato fruit. Its main bioactive compound is lycopene, a powerful antioxidant. It also contains other antioxidants like various phenolic acids and flavonoids.
Superoxide Dismutase
Est. %0.3
Function
Origin
Description is coming soon
Catalase
Est. %0.3
Function
Origin
Description is coming soon
Ergothioneine
Est. %0.3
Function
Origin
A naturally-occurring amino acid that functions as a powerful and versatile antioxidant.
Squalane
Est. %0.3
Function
Origin
An occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Ubiquinone
Est. %0.3
Function
Origin
Also known as Coenzyme Q10, this bright orange antioxidant supports the skin's energy metabolism. It also offers some anti-pigment action. Dietary supplementation of Ubiquinone improves the appearance of wrinkles.
Hydrolyzed Myrtus Communis Leaf Extract
Est. %0.3
Function
Origin
Description is coming soon
Algae Extract
Est. %0.3
Function
Origin
The name describes any extract made from any kind of algae. Algae extracts are moisturizing humectants – the gelatin-like polysaccharides bind and retain water, thereby hydrating the skin. Algae is a rich source of emollient and antioxidant compounds.
Lentinus Edodes Extract
Est. %0.3
Function
Origin
Description is coming soon
Ganoderma Lucidum (Mushroom) Stem Extract
Est. %0.3
Function
Origin
Description is coming soon
Ascophyllum Nodosum Extract
Est. %0.3
Function
Origin
An extract from brown sea algae, a rich source of gel-forming algae polysaccharides such as fucoids, alginate, and ascophyllan, as well as some antioxidant phenolic compounds and minerals.
Carnosine
Est. %0.3
Function
Origin
A skin-identical dipeptide that acts as a powerful antioxidant. It protects our skin from harmful glycation and can enhance the activity of other active ingredients in the skincare product.
Vitis Vinifera (Grape) Seed Extract
Est. %0.3
Function
Origin
A potent antioxidant and emollient extract derived from grape seeds. It contains antioxidant flavonoids, tannins, proanthocyanidins, phytosterols, carotenoids, and vitamin E. It is often used in skincare products aimed at soothing and healing irritated skin.
Resveratrol
Est. %0.3
Function
Origin
A famous plant-based polyphenol found mainly in red grapes. It is a potent antioxidant, soothing, and wound healing ingredient.
Ceramide NP
Est. %0.3
Function
Origin
Also known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Ceramide AP
Est. %0.3
Function
Origin
Previously called Ceramide 6 II, Ceramide AP is one of the most common ceramides in the skin. Research has shown that dry, flaky skin has significantly less Ceramide AP. Its application helps to treat dry skin by restoring balance in the skin lipids.
Ceramide EOP
Est. %0.3
Function
Origin
Formerly called Ceramide 1, this ingredient is a skin-identical wax-like lipid with an ultra-long fatty acid chain. It restores and stabilizes the skin’s lipid matrix and helps to treat dry and flaky skin, especially when combined with other ceramides.
Phytosphingosine
Est. %0.3
Function
Origin
A key component of ceramides NP, AP, and EOP. It has barrier repair properties and stimulates the production of the skin’s Natural Moisturizing Factor. Phytosphingosine has strong antimicrobial and anti-inflammatory activity, which can be used to treat acne.
Cholesterol
Est. %0.3
Function
Origin
An emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Sodium Lauroyl Lactylate
Est. %0.3
Function
Origin
A multifunctional ingredient that produces foamy cleansers and allows oil and water to mix.
Tocopherol
Est. %0.3
Function
Origin
Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.
Astaxanthin
Est. %0.3
Function
Origin
A red natural pigment from the family of antioxidant carotenoids that occurs in many natural sources such as lobster and algae. It is mainly used as a colorant and soothing ingredient.
Vaccinium Macrocarpon (Cranberry) Seed Oil
Est. %0.3
Function
Origin
Derived from cranberry seeds, this rich-in-antioxidants oil contains a combination of emollient and occlusive moisturizing omega-3,-6, and -9 fatty acids.
Panthenol
Est. %0.3
Function
Origin
A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Octyldodecanol
Est. %0.3
Function
Origin
An emollient fatty alcohol that spreads easily without leaving a greasy residue on the skin. It is also used as a solvent and dispersing agent for other ingredients.
Tocopheryl Acetate
Est. %0.3
Function
Origin
An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.
Retinyl Palmitate
Est. %0.3
Function
Origin
An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Ascorbic Acid
Est. %0.3
Function
Origin

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Diazolidinyl Urea
Est. %0.3
Function
Origin
A synthetic preservative that is effective against most common bacteria. It is not considered broad-spectrum because it does not act against any type of yeast or mold. It is therefore commonly paired with antifungal preservatives.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.