AMPLE:N Peptide Shot Ampoule

AMPLE:N Peptide Shot Ampoule
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
1.6Anti-wrinkle icon/ 10
Anti-wrinkle

Review

Does AMPLE:N Peptide Shot Ampoule work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using AMPLE:N Peptide Shot Ampoule:

  • Moderate moisturizing. It has a moisturizing rating of 5.1 out of 10.
  • Little anti-wrinkle effect: AMPLE:N Peptide Shot Ampoule has an anti-wrinkle rating of 1.6 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

How moisturizing is it?

Quite moisturizing: AMPLE:N Peptide Shot Ampoule has a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%) and Butylene Glycol (est. ≈4.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, AMPLE:N Peptide Shot Ampoule has a minimal anti-wrinkle rating of 1.6 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:
    • Niacinamide (est. ≈1.0%),
       one of the most effective and well-researched anti-wrinkle ingredients.
    • Glycolic Acid (est. ≈0.3%),
       highly effective in peelings, yet with below-average anti-wrinkle efficacy when used in leave-on skincare products.
Among others, AMPLE:N Peptide Shot Ampoule also contains some ingredients marketed as effective in reducing wrinkles, specifically Adenosine, Acetyl Hexapeptide-8, Beta-Glucan, Palmitoyl Pentapeptide-4, and Palmitoyl Oligopeptide. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
70
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Butylene Glycol
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Alcohol
Function:
Origin:
PEG-32
Function:
Origin:
Biosaccharide Gum-1
Function:
Origin:
Niacinamide
Function:
Origin:
Trehalose
Function:
Origin:
Adenosine
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Arginine
Function:
Origin:
Panthenol
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Beta-Glucan
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Helichrysum Arenarium Extract
Function:
Origin:
Yeast Extract
Function:
Origin:
Palmitoyl Pentapeptide-4
Function:
Origin:
Pearl Extract
Function:
Origin:
Dimethicone
Function:
Origin:
PEG-60 Hydrogenated Castor Oil
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Carbomer
Function:
Origin:
Xanthan Gum
Function:
Origin:
Titanium Dioxide (CI 77891)
Function:
Origin:
Sodium Palmitoyl Sarcosinate
Function:
Origin:
Glyceryl Acrylate/Acrylic Acid Copolymer
Function:
Origin:
Mica
Function:
Origin:
Caramel
Function:
Origin:
Agar
Function:
Origin:
Calcium Alginate
Function:
Origin:
Gellan Gum
Function:
Origin:
Polysorbate 20
Function:
Origin:
Propylene Glycol
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Glyceryl Caprylate
Function:
Origin:
Phenylpropanol
Function:
Origin:
Palmitoyl Oligopeptide
Function:
Origin:
Lactic Acid
Function:
Origin:
Polyvinyl Alcohol
Function:
Origin:
Glycolic Acid
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Fragrance
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Tetrasodium EDTA
Function:
Origin:

Ratings

All humectants
17.4
6
4
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 17.4 10
10.0
6
4
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
6
4
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 17.4 10
10
All humectants
17.4
6
4
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1 1.5
1.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
1.6
Niacinamide
1.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1
Glycolic Acid
0.1
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Beta-Glucan
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Pentapeptide-4
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Oligopeptide
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
1.6
Ingredient Est. % Benchmark
Rich in Antioxidants
1
0.3
0.3
All antioxidants 1.6 3 No
All antioxidants
1.6
Niacinamide
1
Beta-Glucan
0.3
Pearl Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.3
1
0.3
0.3
0.3
0.3
All soothing 3.5 5 No
All soothing
3.5
1.3
1
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butylene Glycol
Est. %4
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Dipropylene Glycol
Est. %3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Alcohol
Est. %2
Function
Origin
AlcoholAn effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
PEG-32
Est. %1.5
Function
Origin
PEG-32A synthetic water-loving moisturizer that produces water gels.
Biosaccharide Gum-1
Est. %1.3
Function
Origin
Biosaccharide Gum-1A polysaccharide with humectant moisturizing and soothing properties.
Niacinamide
Est. %1
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Trehalose
Est. %0.3
Function
Origin
TrehaloseA sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Beta-Glucan
Est. %0.3
Function
Origin
Beta-GlucanA special polysaccharide obtained from cereals, mushrooms, yeast, bacteria, and some species of seaweed. It is a promising anti-wrinkle, wound healing, antioxidant, and moisturizing ingredient.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Helichrysum Arenarium Extract
Est. %0.3
Function
Origin
Helichrysum Arenarium Extract
Yeast Extract
Est. %0.3
Function
Origin
Yeast ExtractAlso labeled as faex extract, this is a natural ingredient derived from fresh yeast. It is used in skincare as a humectant. Yeast extract also helps to shield injured or exposed skin and can aid in the skin’s wound healing process.
Palmitoyl Pentapeptide-4
Est. %0.3
Function
Origin
Palmitoyl Pentapeptide-4

A famous synthetically made peptide that works as a signal peptide, telling skin cells to create more collagen and other structural proteins. It has been clinically tested and found to be effective at reducing fine wrinkles.

Pearl Extract
Est. %0.3
Function
Origin
Pearl Extract
Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
PEG-60 Hydrogenated Castor Oil
Est. %0.3
Function
Origin
PEG-60 Hydrogenated Castor OilA white paste-like substance derived from castor oil that belongs to a group of ingredients called PEGs (polyethylene glycols). It acts as a perfume solubilizer that helps fragrance agents dissolve in water and as a cleansing agent.
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Titanium Dioxide (CI 77891)
Est. %0.3
Function
Origin
Titanium Dioxide (CI 77891)One of two the most commonly used mineral sunscreens. It can absorb UV light, including UVB – which causes burning, tanning, and even skin cancer. Also used as a colorant, titanium dioxide gives a product a bright white color.
Sodium Palmitoyl Sarcosinate
Est. %0.3
Function
Origin
Sodium Palmitoyl Sarcosinate
Glyceryl Acrylate/Acrylic Acid Copolymer
Est. %0.3
Function
Origin
Glyceryl Acrylate/Acrylic Acid CopolymerA synthetic humectant moisturizer often paired with glycerin. It also functions as a viscosity-controlling agent that creates gel-like formulas with thicker textures.
Mica
Est. %0.3
Function
Origin
MicaA mineral powder made up of silicates with several functions (the main one being as a colorant). It has a shimmery appearance, making it highly desirable in certain cosmetic products. Mica also helps the product to apply more smoothly.
Caramel
Est. %0.3
Function
Origin
CaramelA natural ingredient that is derived from the heat treatment of table sugar. Caramel is used in skincare as a natural colorant that can create transparent, dark brown solutions. It also works as a fragrance, where it provides a sweet, sugary scent.
Agar
Est. %0.3
Function
Origin
AgarA multifunctional jelly derived from red algae that can thicken water-based products.
Calcium Alginate
Est. %0.3
Function
Origin
Calcium Alginate
Gellan Gum
Est. %0.3
Function
Origin
Gellan GumA polysaccharide gel created by a species of bacteria called Sphingomonas elodea. It is used to either create soft, viscous, elastic gels or hard, brittle gels.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Propylene Glycol
Est. %0.3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Glyceryl Caprylate
Est. %0.3
Function
Origin
Glyceryl CaprylateA waxy solid derived from vegetable oils that has emollient and emulsifying properties. It is also known to boost the efficacy of organic acid preservatives by destabilizing the microbe's cell membrane.
Phenylpropanol
Est. %0.3
Function
Origin
PhenylpropanolPhenylpropanol is a naturally occurring component of many essential oils. It is a colourless, oily liquid with a sweet, floral, balsamic scent. It is used in skincare as a solvent for oil-soluble ingredients and as a fragrance component.
Palmitoyl Oligopeptide
Est. %0.3
Function
Origin
Palmitoyl Oligopeptide

This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity.

Lactic Acid
Est. %0.3
Function
Origin
Lactic AcidThe most popular AHA in skincare and less irritating than glycolic acid. It can be naturally found in sour milk. It is a humectant moisturizing, pH stabilizing, and gently exfoliating ingredient, able to soften dry, cracked, and peeling skin.
Polyvinyl Alcohol
Est. %0.3
Function
Origin
Polyvinyl AlcoholA synthetic polymer that thickens water to form a gel and prevents other ingredients from separating.
Glycolic Acid
Est. %0.3
Function
Origin
Glycolic Acid

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Tetrasodium EDTA
Est. %0.3
Function
Origin
Tetrasodium EDTAOne of the most common synthetic chelators. It can reduce the 'hardness' of water and so is often used in rinse-off products.