Advanced Clinicals Retinol + Niacinamide Body Lotion Review

Advanced Clinicals Retinol + Niacinamide Body Lotion
5.7
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.4 Occlusivity icon Occlusivity
2.9Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does Advanced Clinicals Retinol + Niacinamide Body Lotion Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Advanced Clinicals Retinol + Niacinamide Body Lotion has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.7 out of 10.
  • Modest anti-wrinkle efficacy: Advanced Clinicals Retinol + Niacinamide Body Lotion has an anti-wrinkle rating of 2.9 out of 10 so you may expect some, although limited, effect on wrinkles.

Key Benefits of Advanced Clinicals Retinol + Niacinamide Body Lotion

 
These are the key benefits you can expect from using Advanced Clinicals Retinol + Niacinamide Body Lotion:
 

Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Advanced Clinicals Retinol + Niacinamide Body Lotion is quite moisturizing, with a moisturizing rating of 5.7 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.4 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Advanced Clinicals Retinol + Niacinamide Body Lotion has a modest level of anti-wrinkle efficacy, rated 2.9 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

  • Retinol (est. ≈0.1%),
     the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
  • Niacinamide (est. ≈0.3%),
     one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Advanced Clinicals Retinol + Niacinamide Body Lotion

 
CreamScan AI identified a few things to consider before adding Advanced Clinicals Retinol + Niacinamide Body Lotion to your skincare routine:
 

May Increase Skin Photosensitivity Due to Retinol

This product contains retinol, which offers powerful anti-wrinkle benefits. The mechanism behind retinol’s action is boosting cell turnover. This process exposes new, more delicate skin, making it more vulnerable to sun damage.

As a result, using products with retinol may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To protect the skin, dermatologists recommend applying a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment, along with avoiding direct sun exposure. Retinol should be used at night, as it is sensitive to sunlight and can lose its potency when exposed to UV rays.

Please always check the manufacturer's instructions for using the retinol-containing products, either on their website or product label.

Pros & Cons of Advanced Clinicals Retinol + Niacinamide Body Lotion

 
Here’s an overview of the pros and cons of Advanced Clinicals Retinol + Niacinamide Body Lotion to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Offers modest anti-wrinkle efficacy

Cons: 

  • May increase skin photosensitivity due to retinol

Ingredients

Est. % Ingredient Origin Functions
70
9
6
4
3
2.5
2
0.1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Caprylic Acid
Function:
Origin:
C13-15 Alkane
Function:
Origin:
Butyrospermum Parkii (Shea) Butter
Function:
Origin:
C18-21 Alkane
Function:
Origin:
Retinol
Function:
Origin:
Aloe Barbadensis Leaf Juice
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Cetearyl Phosphate
Function:
Origin:
Synthetic Beeswax
Function:
Origin:
Niacinamide
Function:
Origin:
Oryza Sativa (Rice) Bran Extract
Function:
Origin:
Helianthus Annuus (Sunflower) Extract
Function:
Origin:
Rosmarinus Officinalis (Rosemary) Leaf Extract
Function:
Origin:
Xanthan Gum
Function:
Origin:
Tocopherol
Function:
Origin:
Carbomer
Function:
Origin:
Tetrasodium Glutamate Diacetate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Hexylene Glycol
Function:
Origin:
BHT
Function:
Origin:
Sodium Hydroxide
Function:
Origin:

Ratings

All humectants
10.2
9
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
2.8
2.5
0.3
Benchmark
20
Moisturizing rating
5.7
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.2 10
10.0
9
0.3
0.3
0.3
0.3
Occlusivity All occlusives 2.8 20
1.4
2.5
0.3
Moisturizing rating
5.7
Ingredient Est. % Benchmark Humectancy
9
0.3
0.3
0.3
0.3
All humectants 10.2 10
10
All humectants
10.2
9
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
2.5
0.3
All occlusives 2.8 20
1.4
All occlusives
2.8
2.5
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.1 2.5
6 /10 4 0.3 0.4
Total
2.9
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Anti-wrinkle rating
2.9
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
All antioxidants 1.5 3 No
All antioxidants
1.5
Niacinamide
0.3
Aloe Barbadensis Leaf Juice
0.3
Rosmarinus Officinalis (Rosemary) Leaf Extract
0.3
Tocopherol
0.3
BHT
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
0.3
All soothing 1.2 5 No
All soothing
1.2
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Cetyl Alcohol
Est. %6
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Caprylic Acid
Est. %4
Function
Origin
Caprylic Acid
C13-15 Alkane
Est. %3
Function
Origin
C13-15 Alkane
Butyrospermum Parkii (Shea) Butter
Est. %2.5
Function
Origin
Butyrospermum Parkii (Shea) ButterA semi-solid, buttery fat extracted from the seeds of the Shea tree that is a wonderful occlusive and emollient ingredient mainly comprised of fatty acids. Shea butter contains a large amount of anti-inflammatory and antioxidant compounds.
C18-21 Alkane
Est. %2
Function
Origin
C18-21 Alkane
Retinol
Est. %0.1
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Aloe Barbadensis Leaf Juice
Est. %0.3
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Cetearyl Phosphate
Est. %0.3
Function
Origin
Cetearyl Phosphate
Synthetic Beeswax
Est. %0.3
Function
Origin
Synthetic BeeswaxA synthetic blend of fatty acids, fatty alcohols, and other ingredients that are combined to mimic natural beeswax.
Niacinamide
Est. %0.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Oryza Sativa (Rice) Bran Extract
Est. %0.3
Function
Origin
Oryza Sativa (Rice) Bran ExtractAn extract from rice bran, the brown outer part of the rice kernel. It contains emollient fatty acids and antioxidants such as tocopherols (vitamin E) and γ-oryzanol.
Helianthus Annuus (Sunflower) Extract
Est. %0.3
Function
Origin
Helianthus Annuus (Sunflower) ExtractAn emollient extract derived from sunflower seeds that is packed with skin-benefiting ingredients such as squalene, phytosterols, phospholipids, amino acids, and antioxidant vitamin E.
Rosmarinus Officinalis (Rosemary) Leaf Extract
Est. %0.3
Function
Origin
Rosmarinus Officinalis (Rosemary) Leaf ExtractA soothing and astringent extract derived from the fragrant, spicy leaves of rosemary. It has strong antioxidant properties. Rosemary extract can reduce signs of inflammation and also acts as an emollient and antimicrobial agent.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Tetrasodium Glutamate Diacetate
Est. %0.3
Function
Origin
Tetrasodium Glutamate DiacetateA biodegradable chelating agent that chemically captures the heavy metal ions naturally present in water and disarms their harmful effects.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Hexylene Glycol
Est. %0.3
Function
Origin
Hexylene GlycolA multifunctional ingredient that is best known for its use as a solvent. It can dissolve both water-based ingredients and oils. For this reason, it can also function as an emulsifier, allowing oil and water ingredients to mix and remain stable.
BHT
Est. %0.3
Function
Origin
BHTAn antioxidant ingredient that naturally occurs in green algae and some bacteria or fungi but, for commercial use, is created synthetically. BHT is also used occasionally as a fragrance, where it presents a sweet, camphor-like odor.
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.