TONYMOLY Bio EX Cell Peptide Ampoule Review

TONYMOLY Bio EX Cell Peptide Ampoule
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
4.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Review

Does TONYMOLY Bio EX Cell Peptide Ampoule Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what TONYMOLY Bio EX Cell Peptide Ampoule has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Considerable anti-wrinkle efficacy: TONYMOLY Bio EX Cell Peptide Ampoule has an anti-wrinkle rating of 4.5 out of 10, indicating a moderate ability to reduce wrinkles.
  • Antioxidant protection.

Key Benefits of TONYMOLY Bio EX Cell Peptide Ampoule

 
These are the key benefits you can expect from using TONYMOLY Bio EX Cell Peptide Ampoule:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, TONYMOLY Bio EX Cell Peptide Ampoule is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%), Butylene Glycol (est. ≈4.0%) and Niacinamide (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Considerable Anti-Wrinkle Efficacy

According to CreamScan analysis, TONYMOLY Bio EX Cell Peptide Ampoule has a moderate anti-wrinkle rating of 4.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈3.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, TONYMOLY Bio EX Cell Peptide Ampoule also contains contains Acetyl Hexapeptide-8 and Adenosine, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that TONYMOLY Bio EX Cell Peptide Ampoule is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: TONYMOLY Bio EX Cell Peptide Ampoule

 
CreamScan AI identified a few things to consider before adding TONYMOLY Bio EX Cell Peptide Ampoule to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using TONYMOLY Bio EX Cell Peptide Ampoule as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of TONYMOLY Bio EX Cell Peptide Ampoule

 
Here’s an overview of the pros and cons of TONYMOLY Bio EX Cell Peptide Ampoule to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Provides considerable anti-wrinkle efficacy thanks to Niacinamide
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage

Cons: 

  • Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Butylene Glycol
Function:
Origin:
Niacinamide
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Glyceryl Acrylate/Acrylic Acid Copolymer
Function:
Origin:
PVM/MA Copolymer
Function:
Origin:
Polyglutamic Acid
Function:
Origin:
Crithmum Maritimum Callus Culture Filtrate
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Hexacarboxymethyl Dipeptide-12
Function:
Origin:
Oligopeptide-91 rh-Oligopeptide-1
Function:
Origin:
Fullerenes
Function:
Origin:
Sodium Dilauramidoglutamide Lysine
Function:
Origin:
PVP
Function:
Origin:
Theanine
Function:
Origin:
Milk Lipids
Function:
Origin:
Acmella Oleracea Extract
Function:
Origin:
Glutathione
Function:
Origin:
Allantoin
Function:
Origin:
Adenosine
Function:
Origin:
Tromethamine
Function:
Origin:
Carbomer
Function:
Origin:
Xanthan Gum
Function:
Origin:
PPG-26-Buteth-26
Function:
Origin:
PEG-40 Hydrogenated Castor Oil
Function:
Origin:
Hydroxyacetophenone
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Propanediol
Function:
Origin:
Disodium EDTA
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
17.6
6
4
3
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 17.6 10
10.0
6
4
3
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
3
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 17.6 10
10
All humectants
17.6
6
4
3
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 3 4.5
n/a
- 0.3 -
n/a
- 0.3 -
Total
4.5
Niacinamide
4.5
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
3
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
4.5
Ingredient Est. % Benchmark
Rich in Antioxidants
3
0.3
0.3
All antioxidants 3.6 3 Rich in antioxidants
All antioxidants
3.6
Niacinamide
3
Glutathione
0.3
Hydroxyacetophenone
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
0.3
0.3
All soothing 3.6 5 No
All soothing
3.6
3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Butylene Glycol
Est. %4
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Niacinamide
Est. %3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

1,2-Hexanediol
Est. %2
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Glyceryl Acrylate/Acrylic Acid Copolymer
Est. %1.5
Function
Origin
Glyceryl Acrylate/Acrylic Acid CopolymerA synthetic humectant moisturizer often paired with glycerin. It also functions as a viscosity-controlling agent that creates gel-like formulas with thicker textures.
PVM/MA Copolymer
Est. %1.3
Function
Origin
PVM/MA Copolymer
Polyglutamic Acid
Est. %1
Function
Origin
Polyglutamic AcidA natural polymer with incredible water-binding properties that is prepared from glutamic acid through fermentation.
Crithmum Maritimum Callus Culture Filtrate
Est. %0.3
Function
Origin
Crithmum Maritimum Callus Culture Filtrate
Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Hexacarboxymethyl Dipeptide-12
Est. %0.3
Function
Origin
Hexacarboxymethyl Dipeptide-12
Oligopeptide-91 rh-Oligopeptide-1
Est. %0.3
Function
Origin
Oligopeptide-91 rh-Oligopeptide-1
Fullerenes
Est. %0.3
Function
Origin
Fullerenes
Sodium Dilauramidoglutamide Lysine
Est. %0.3
Function
Origin
Sodium Dilauramidoglutamide Lysine
PVP
Est. %0.3
Function
Origin
PVPAn excellent film-former used in hairsprays, peel-off masks, and even some self-tanning products. These films are strong and hold onto the skin.
Theanine
Est. %0.3
Function
Origin
TheanineAn amino acid derived from green tea extract. It has humectant properties, retains water to the skin’s surface, and offers additional soothing and immunomodulatory benefits.
Milk Lipids
Est. %0.3
Function
Origin
Milk Lipids
Acmella Oleracea Extract
Est. %0.3
Function
Origin
Acmella Oleracea Extract
Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
PPG-26-Buteth-26
Est. %0.3
Function
Origin
PPG-26-Buteth-26A water-loving surfactant, which means it can act as an emulsifier, solubilizer, and cleansing agent. As an emulsifier, it helps to create oil-in-water emulsions.
PEG-40 Hydrogenated Castor Oil
Est. %0.3
Function
Origin
PEG-40 Hydrogenated Castor OilA castor oil-derived ingredient often used to incorporate small amounts of oil (such as a fragrance) into a water-based product. PEG-4 HCO is a gold-standard solubilizer and can be used in low amounts due to its ability to solubilize things so well.
Hydroxyacetophenone
Est. %0.3
Function
Origin
HydroxyacetophenoneAn antioxidant compound that can be found in many plants, although it is manufactured synthetically for skincare purposes. It can boost the preservative action of other conservants.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Propanediol
Est. %0.3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.