SCINIC First Treatment Mist Review

SCINIC First Treatment Mist
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does SCINIC First Treatment Mist Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what SCINIC First Treatment Mist has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
✅ Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, SCINIC First Treatment Mist is effective in minimizing wrinkles.
✅ Soothing: SCINIC First Treatment Mist contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of SCINIC First Treatment Mist

 
These are the key benefits you can expect from using SCINIC First Treatment Mist:
 

🔵 Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, SCINIC First Treatment Mist is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? Question icon The Humectancy (from 0 to 10) is based on the amount of humectants in the formula and indicates how well the product can attract moisture to the skin. Humectants are effective moisturizers that work well for all skin types. The Occlusivity (from 0 to 10) is based on the amount of occlusives in the formula and indicates how effective the product is at sealing moisture into the skin. Occlusive moisturizers are ideal for those with dry skin. Question icon The Humectancy (from 0 to 10) is based on the amount of humectants in the formula and indicates how well the product can attract moisture to the skin. Humectants are effective moisturizers that work well for all skin types. The Occlusivity (from 0 to 10) is based on the amount of occlusives in the formula and indicates how effective the product is at sealing moisture into the skin. Occlusive moisturizers are ideal for those with dry skin. It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Galactomyces Ferment Filtrate (est. ≈50.0%), Glycerin (est. ≈22.0%) and Niacinamide (est. ≈5.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

📌 Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, SCINIC First Treatment Mist has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈5.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, SCINIC First Treatment Mist contains some ingredients often marketed as effective in reducing wrinkles, specifically Adenosine, Sodium Ascorbyl Phosphate, Folic Acid, and Retinyl Palmitate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that SCINIC First Treatment Mist is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈5.0%), Glycyrrhiza Glabra (Licorice) Root Water (est. ≈3.0%) and Portulaca Oleracea Extract (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, SCINIC First Treatment Mist is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈5.0%) and Portulaca Oleracea Extract (est. ≈2.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: SCINIC First Treatment Mist

 
CreamScan AI identified a few things to consider before adding SCINIC First Treatment Mist to your skincare routine:
 

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using SCINIC First Treatment Mist as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of SCINIC First Treatment Mist

 
Here’s an overview of the pros and cons of SCINIC First Treatment Mist to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers signficant anti-wrinkle efficacy thanks to Niacinamide
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients like Niacinamide and Portulaca Oleracea Extract
 

⭕ Cons: 

⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
   

Summary: SCINIC First Treatment Mist

 
Based on the ingredient list analysis, CreamScan AI suggests that SCINIC First Treatment Mist
 is specifically effective in treating wrinkles, containing ingredients with solid, robust evidence of anti-wrinkle efficacy.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, SCINIC First Treatment Mist helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
That said, there are some things about SCINIC First Treatment Mist worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
50
22
5
4.9
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Galactomyces Ferment Filtrate
Function:
Origin:
Glycerin
Function:
Origin:
Niacinamide
Function:
Origin:
Propanediol
Function:
Origin:
Water
Function:
Origin:
Glycyrrhiza Glabra (Licorice) Root Water
Function:
Origin:
Portulaca Oleracea Extract
Function:
Origin:
Rubus Coreanus Fruit Extract
Function:
Origin:
Sea Water
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Adenosine
Function:
Origin:
Sodium Citrate
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Citric Acid
Function:
Origin:
Disodium EDTA
Function:
Origin:
Polyglyceryl-4 Caprate
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Polyglyceryl-10 Palmate
Function:
Origin:
Sodium Ascorbyl Phosphate
Function:
Origin:
Panthenol
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Glyceryl Arachidonate
Function:
Origin:
Glyceryl Linolenate
Function:
Origin:
Biotin
Function:
Origin:
Folic Acid
Function:
Origin:
Pyridoxine
Function:
Origin:
Retinyl Palmitate
Function:
Origin:
Thiamine HCl
Function:
Origin:
Cyanocobalamin
Function:
Origin:
Arginine
Function:
Origin:
Calcium Carbonate
Function:
Origin:
Dextrin
Function:
Origin:
Hydroxypropyl Methylcellulose
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:

Ratings

All humectants
86.4
50
22
5
4.9
2
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 86.4 10
10.0
50
22
5
4.9
2
1
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
50
22
5
4.9
2
1
0.3
0.3
0.3
0.3
0.3
All humectants 86.4 10
10
All humectants
86.4
50
22
5
4.9
2
1
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 5 6
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
5
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Sodium Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Folic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
5
3
2
0.3
0.3
0.3
All antioxidants 10.9 3 Rich in antioxidants
All antioxidants
10.9
Niacinamide
5
Glycyrrhiza Glabra (Licorice) Root Water
3
Portulaca Oleracea Extract
2
Sodium Ascorbyl Phosphate
0.3
Tocopheryl Acetate
0.3
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
5
2
0.3
0.3
All soothing 7.6 5 Rich in soothing
All soothing
7.6
5
2
0.3
0.3
Benchmark
5

Ingredients explained

Galactomyces Ferment Filtrate
Est. %50
Function
Origin
Galactomyces Ferment Filtrate
Glycerin
Est. %22
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Niacinamide
Est. %5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Propanediol
Est. %4.9
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Water
Est. %4
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycyrrhiza Glabra (Licorice) Root Water
Est. %3
Function
Origin
Glycyrrhiza Glabra (Licorice) Root Water
Portulaca Oleracea Extract
Est. %2
Function
Origin
Portulaca Oleracea ExtractDerived from green or common purslane, this moisturizing extract is particularly rich in alpha-linolenic acid, an omega-3 fatty acid, and contains antioxidant glutathione and vitamin E. As a herbal medicine, it is believed to treat headaches and inflammation.
Rubus Coreanus Fruit Extract
Est. %1.5
Function
Origin
Rubus Coreanus Fruit Extract
Sea Water
Est. %1
Function
Origin
Sea WaterA water obtained from oceans, seas, and large saltwater lakes. The water has been purified, and what remains is a complex mixture of various mineral salts that have beneficial effects on the skin. Sea water is used as a humectant and a solvent.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Polyglyceryl-4 Caprate
Est. %0.3
Function
Origin
Polyglyceryl-4 CaprateA natural surfactant that softens the appearance of skin and forms oil and water mixtures.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Polyglyceryl-10 Palmate
Est. %0.3
Function
Origin
Polyglyceryl-10 Palmate
Sodium Ascorbyl Phosphate
Est. %0.3
Function
Origin
Sodium Ascorbyl PhosphateThe most researched derivative of vitamin C. It boosts collagen synthesis, thereby improving skin structure and elasticity. SAP is effective in the treatment of inflamed acne lesions and has a weak but positive effect on pigmentation issues.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Glyceryl Arachidonate
Est. %0.3
Function
Origin
Glyceryl Arachidonate
Glyceryl Linolenate
Est. %0.3
Function
Origin
Glyceryl Linolenate
Biotin
Est. %0.3
Function
Origin
BiotinBiotin is an important nutrient that can cause weak hair and nails if deficient. Unfortunately, while biotin supplements have promising studies, topical biotin in creams and serums doesn’t have a large body of evidence to support its use.
Folic Acid
Est. %0.3
Function
Origin
Folic AcidA critical vitamin for the body that needs more research for topical applications.
Pyridoxine
Est. %0.3
Function
Origin
PyridoxinePyridoxine, also known as vitamin B6, is required by the body to produce amino acids, carbohydrates, and lipids. Its benefits in skincare have not been researched as of yet.
Retinyl Palmitate
Est. %0.3
Function
Origin
Retinyl PalmitateAn esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Thiamine HCl
Est. %0.3
Function
Origin
Thiamine HClAlso known as vitamin B1, the benefits of this ingredient in skincare are not yet clear. It may have some benefits to energy metabolism, but this hasn't been confirmed. It has a typical, sulfur-like smell.
Cyanocobalamin
Est. %0.3
Function
Origin
CyanocobalaminA product of bacterial fermentation that may have soothing and rejuvenating skin effects.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Calcium Carbonate
Est. %0.3
Function
Origin
Calcium Carbonate
Dextrin
Est. %0.3
Function
Origin
DextrinA partially hydrolyzed potato starch, most commonly used as a viscosity controlling and binding agent. When dispersed into water, it can create textures ranging from a thick paste to a soft gel.
Hydroxypropyl Methylcellulose
Est. %0.3
Function
Origin
Hydroxypropyl MethylcelluloseA natural viscosity controlling agent that is commonly used in skin cleansing products to thicken the consistency. It also functions as an emulsion stabilizing agent and binding agent.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.