Replenix AE Dermal Restructuring Therapy

Replenix AE Dermal Restructuring Therapy
6.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
2.2 Occlusivity icon Occlusivity
0.4Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
$$$$

Review

Results you may expect from using Replenix AE Dermal Restructuring Therapy:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Replenix AE Dermal Restructuring Therapy:

  • Significant moisturizing. It has a moisturizing rating of 6.1 out of 10.
  • Little anti-wrinkle effect: Replenix AE Dermal Restructuring Therapy has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Highly moisturizing: Replenix AE Dermal Restructuring Therapy has a moisturizing rating of 6.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 2.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈9.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Replenix AE Dermal Restructuring Therapy has a minimal anti-wrinkle rating of 0.4 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Ectoin (est. ≈0.3%),
 an amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.
 
Among others, Replenix AE Dermal Restructuring Therapy also contains some ingredients marketed as effective in reducing wrinkles, specifically Palmitoyl Pentapeptide-4, Camellia Sinensis Leaf Extract, Ascorbyl Palmitate, Retinyl Palmitate, and Ubiquinone. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Replenix AE Dermal Restructuring Therapy is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈1.3%), Camellia Sinensis Polyphenols (est. ≈0.3%), Camellia Sinensis Leaf Extract (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
65
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
11.8
9
1.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
4.5
3.0
1.5
Benchmark
20
Moisturizing rating
6.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 11.8 10
10.0
9
1.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 4.5 20
2.2
3.0
1.5
Moisturizing rating
6.1
Ingredient Est. % Benchmark Humectancy
9
1.3
0.3
0.3
0.3
0.3
0.3
All humectants 11.8 10
10
All humectants
11.8
9
1.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
3
1.5
All occlusives 4.5 20
2.2
All occlusives
4.5
3.0
1.5
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2.5 /10 2 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.4
Ectoin
0.4
Ingredient anti-wrinkle power
2.5 /10
when present at, %
2
in this formula, est. %
0.3
Palmitoyl Pentapeptide-4
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ascorbyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Ubiquinone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.4
Ingredient Est. % Benchmark
Rich in Antioxidants
1.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 3.1 3 Rich in antioxidants
All antioxidants
3.1
Sodium Hyaluronate
1.3
Camellia Sinensis Polyphenols
0.3
Camellia Sinensis Leaf Extract
0.3
Ascorbyl Palmitate
0.3
Tocopheryl Acetate
0.3
Superoxide Dismutase
0.3
Ubiquinone
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %9
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

PPG-2 Myristyl Ether Propionate
Est. %6
Function
Origin
A synthetically prepared emollient that leaves the skin smooth and soft without a greasy or sticky after-feel.
Cetearyl Alcohol
Est. %4
Function
Origin
A blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Squalane
Est. %3
Function
Origin
An occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Cetyl Alcohol
Est. %2.5
Function
Origin
A waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Polysorbate 60
Est. %2
Function
Origin
An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Dimethicone
Est. %1.5
Function
Origin
The most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Sodium Hyaluronate
Est. %1.3
Function
Origin

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Phyllanthus Emblica Extract
Est. %1
Function
Origin
Description is coming soon
Camellia Sinensis Polyphenols
Est. %0.3
Function
Origin
Description is coming soon
Palmitoyl Pentapeptide-4
Est. %0.3
Function
Origin

A famous synthetically made peptide that works as a signal peptide, telling skin cells to create more collagen and other structural proteins. It has been clinically tested and found to be effective at reducing fine wrinkles.

Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Ectoin
Est. %0.3
Function
Origin

An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.

Bisabolol
Est. %0.3
Function
Origin
An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.
Phospholipids
Est. %0.3
Function
Origin
A large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Saccharomyces Lysate Extract
Est. %0.3
Function
Origin
A mixture of yeast cell fragments with humectant moisturizing properties. It contains many beneficial compounds, including a wound healing polysaccharide called beta-glucan, peptides, and various minerals and vitamins.
Ascorbyl Palmitate
Est. %0.3
Function
Origin
A form of vitamin C derived from ascorbic acid and palmitic acid. It is more stable and less irritating than ascorbic acid. Unfortunately, Ascorbyl Palmitate lacks the studies to prove its anti-wrinkle efficacy.
Tocopheryl Acetate
Est. %0.3
Function
Origin

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Retinyl Palmitate
Est. %0.3
Function
Origin
An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Polysorbate 20
Est. %0.3
Function
Origin
A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Ceramide NS
Est. %0.3
Function
Origin
A wax-like lipid natural to the skin’s lipid matrix. It is less frequently used but, in combination with other ceramides, can help to restore balance in the skin’s lipid barrier.
Carbomer
Est. %0.3
Function
Origin
A synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Superoxide Dismutase
Est. %0.3
Function
Origin
Description is coming soon
Ubiquinone
Est. %0.3
Function
Origin
Also known as Coenzyme Q10, this bright orange antioxidant supports the skin's energy metabolism. It also offers some anti-pigment action. Dietary supplementation of Ubiquinone improves the appearance of wrinkles.
Lecithin
Est. %0.3
Function
Origin
A humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Potassium Hydroxide
Est. %0.3
Function
Origin
A very alkaline ingredient, meaning that it has a high pH. Potassium hydroxide is therefore useful in bringing a low pH in a cosmetic product up to a more neutral, skin-safe level.
Sorbic Acid
Est. %0.3
Function
Origin
An organic acid that can be naturally found in the berries of the Mountain ash, although it is manufactured synthetically for skincare purposes. It is used as a preservative and antimicrobial agent, protecting a skincare product from spoiling.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.