Physiogel Demelanizer Toning Ampoule Serum Review

Physiogel Demelanizer Toning Ampoule Serum
5.6
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
1.2 Occlusivity icon Occlusivity
6.1Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Physiogel Demelanizer Toning Ampoule Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Physiogel Demelanizer Toning Ampoule Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.6 out of 10.
✅ Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.1 out of 10, Physiogel Demelanizer Toning Ampoule Serum is effective in minimizing wrinkles.
✅ Soothing: Physiogel Demelanizer Toning Ampoule Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of Physiogel Demelanizer Toning Ampoule Serum

 
These are the key benefits you can expect from using Physiogel Demelanizer Toning Ampoule Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Physiogel Demelanizer Toning Ampoule Serum is quite moisturizing, with a moisturizing rating of 5.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 1.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Niacinamide (est. ≈5.0%), Pentylene Glycol (est. ≈3.0%) and Butylene Glycol (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, Physiogel Demelanizer Toning Ampoule Serum has a high anti-wrinkle rating of 6.1 out of 10.

It contains 2 active ingredients with proven anti-wrinkle efficacy:

1️⃣ Niacinamide (est. ≈5.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
2️⃣ Ascorbic Acid (est. ≈0.3%),
 or Vitamin C, a popular ingredient, yet with moderate anti-wrinkle efficacy, as confirmed by a single clinical study involving 20 participants (Humbert et al.). This study showed that a cream with a relatively high concentration of 5% ascorbic acid reduced the average wrinkle depth by 7% after 6 months of use, compared to a vehicle (the same formulation without ascorbic acid).
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Physiogel Demelanizer Toning Ampoule Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈5.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, Physiogel Demelanizer Toning Ampoule Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈5.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Physiogel Demelanizer Toning Ampoule Serum

 
Here’s an overview of the pros and cons of Physiogel Demelanizer Toning Ampoule Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers signficant anti-wrinkle efficacy thanks to Niacinamide and Ascorbic Acid
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients, specifically Niacinamide
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Physiogel Demelanizer Toning Ampoule Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Physiogel Demelanizer Toning Ampoule Serum
 is specifically effective in treating wrinkles, containing ingredients with solid, robust evidence of anti-wrinkle efficacy.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, Physiogel Demelanizer Toning Ampoule Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
70
5
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Niacinamide
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
C15-19 Alkane
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Panthenol
Function:
Origin:
Phloretin
Function:
Origin:
Phytosterols
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Myristica Fragrans (Nutmeg) Extract
Function:
Origin:
Macadamia Ternifolia Seed Oil
Function:
Origin:
Olea Europaea (Olive) Fruit Oil
Function:
Origin:
Simmondsia Chinensis (Jojoba) Seed Oil
Function:
Origin:
Vitis Vinifera (Grape) Seed Oil
Function:
Origin:
Vetiveria Zizanoides Root Oil
Function:
Origin:
Rosa Damascena Flower Oil
Function:
Origin:
Salvia Sclarea (Clary) Oil
Function:
Origin:
Glycine Soja (Soybean) Oil
Function:
Origin:
Ascorbic Acid
Function:
Origin:
Ferulic Acid
Function:
Origin:
Tocopherol
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Coco-Caprylate/Caprate
Function:
Origin:
Squalane
Function:
Origin:
Hydrogenated Lecithin
Function:
Origin:
Ceramide NP
Function:
Origin:
Sucrose Palmitate
Function:
Origin:
2,3-Butanediol
Function:
Origin:
Isohexadecane
Function:
Origin:
Isononyl Isononanoate
Function:
Origin:
Methyl Glucose Sesquistearate
Function:
Origin:
Methyl Methacrylate Crosspolymer
Function:
Origin:
Sclerotium Gum
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Sodium Carbomer
Function:
Origin:
Carbomer
Function:
Origin:
Ammonium Polyacryloyldimethyl Taurate
Function:
Origin:
Succinoglycan
Function:
Origin:
Tromethamine
Function:
Origin:
Trisodium EDTA
Function:
Origin:

Ratings

All humectants
12.4
5
3
2
1.5
0.3
0.3
0.3
Benchmark
10
All occlusives
2.4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.4 10
10.0
5
3
2
1.5
0.3
0.3
0.3
Occlusivity All occlusives 2.4 20
1.2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Moisturizing rating
5.6
Ingredient Est. % Benchmark Humectancy
5
3
2
1.5
0.3
0.3
0.3
All humectants 12.4 10
10
All humectants
12.4
5
3
2
1.5
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All occlusives 2.4 20
1.2
All occlusives
2.4
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 5 6
2.5 /10 5 0.3 0.1
Total
6.1
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
5
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Anti-wrinkle rating
6.1
Ingredient Est. % Benchmark
Rich in Antioxidants
5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 7.7 3 Rich in antioxidants
All antioxidants
7.7
Niacinamide
5
Ascorbic Acid
0.3
Phloretin
0.3
Phytosterols
0.3
Olea Europaea (Olive) Fruit Oil
0.3
Vitis Vinifera (Grape) Seed Oil
0.3
Rosa Damascena Flower Oil
0.3
Glycine Soja (Soybean) Oil
0.3
Ferulic Acid
0.3
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
5
0.3
0.3
All soothing 5.6 5 Rich in soothing
All soothing
5.6
5
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %70
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Niacinamide
Est. %5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Dipropylene Glycol
Est. %4
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Pentylene Glycol
Est. %3
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Butylene Glycol
Est. %2
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

C15-19 Alkane
Est. %1.3
Function
Origin
C15-19 Alkane
1,2-Hexanediol
Est. %1
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Phloretin
Est. %0.3
Function
Origin
Phloretin
Phytosterols
Est. %0.3
Function
Origin
PhytosterolsA plant-based version of cholesterol that is used for its emollient properties in skincare. The richest sources of phytosterols are corn, rapeseed, and wheat germ oil.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Myristica Fragrans (Nutmeg) Extract
Est. %0.3
Function
Origin
Myristica Fragrans (Nutmeg) Extract
Macadamia Ternifolia Seed Oil
Est. %0.3
Function
Origin
Macadamia Ternifolia Seed OilAn occlusive moisturizing and emollient oil extracted from macadamia nuts. It is clear and pale yellow with a pleasant nutty aroma and contains oleic and palmitoleic fatty acids, tocopherols, phytosterols, squalene, and polyphenols.
Olea Europaea (Olive) Fruit Oil
Est. %0.3
Function
Origin
Olea Europaea (Olive) Fruit Oil

A famous olive oil widely used in skincare as an emollient and occlusive moisturizer. It contains mainly unsaturated fatty acids, antioxidant flavonoids, and oleuropeins. Olive oil is listed as a common comedogenic ingredient by acne.org.

Simmondsia Chinensis (Jojoba) Seed Oil
Est. %0.3
Function
Origin
Simmondsia Chinensis (Jojoba) Seed OilA liquid plant wax, also known as Jojoba oil, pressed from the seeds of Simmondsia chinensis. These seeds can contain up to 50% of liquid wax. It is used as an occlusive moisturizer, emollient, and emulsifier.
Vitis Vinifera (Grape) Seed Oil
Est. %0.3
Function
Origin
Vitis Vinifera (Grape) Seed OilAn emollient and occlusive moisturizing oil derived from grape seeds that are leftover after juicing or wine production. It contains linoleic, oleic, palmitic, and stearic acids, squalene, as well as phytosterols and various antioxidant compounds.
Vetiveria Zizanoides Root Oil
Est. %0.3
Function
Origin
Vetiveria Zizanoides Root Oil
Rosa Damascena Flower Oil
Est. %0.3
Function
Origin
Rosa Damascena Flower OilAlso known as Damask rose oil, it is one of the most precious and expensive essential oils in the world obtained from the petals of the Damask rose. It is used in skincare as a luxurious fragrance.
Salvia Sclarea (Clary) Oil
Est. %0.3
Function
Origin
Salvia Sclarea (Clary) OilA fragrant essential oil obtained from the clary sage that has a sweet, herbal, soft, and woody aroma, with some hints of lavender.
Glycine Soja (Soybean) Oil
Est. %0.3
Function
Origin
Glycine Soja (Soybean) OilAn occlusive moisturizing oil expressed from soybeans. It does not leave an oily feeling on the skin due to its low content of saturated fatty acids. Glycine soja oil contains emollient fatty acids and a significant amount of antioxidants.
Ascorbic Acid
Est. %0.3
Function
Origin
Ascorbic Acid

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Ferulic Acid
Est. %0.3
Function
Origin
Ferulic AcidA plant-based phenolic acid with powerful and scientifically proven antioxidant properties. It enhances the effects of vitamins C and E, as well as the UV protective effects of sunscreens.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Coco-Caprylate/Caprate
Est. %0.3
Function
Origin
Coco-Caprylate/CaprateA naturally-derived emollient ester. It is a blend of caprylates and caprates and, relative to other emollients, is lightweight and dry on the skin. As a result, coco-caprylate/caprate serves as a natural alternative to volatile silicones.
Squalane
Est. %0.3
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Hydrogenated Lecithin
Est. %0.3
Function
Origin
Hydrogenated LecithinA version of plain lecithin that has been saturated with hydrogen atoms. This ingredient can be derived from plants, like soy or sunflower, from egg yolks, or made synthetically. Its major function is to emulsify water and oils.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Sucrose Palmitate
Est. %0.3
Function
Origin
Sucrose PalmitateSucrose palmitate is a sugar-based emulsifier, typically used in lotions or creams that are oil in water emulsions. One of the main benefits to these kinds of emulsifiers is their sustainability, but they are also milder on the skin.
2,3-Butanediol
Est. %0.3
Function
Origin
2,3-Butanediol
Isohexadecane
Est. %0.3
Function
Origin
IsohexadecaneA clear, colorless liquid that is commonly used as an emollient. It is made up of pure hydrocarbons and leaves a dry feeling on the skin upon application. It also increases the spreadability of a product.
Isononyl Isononanoate
Est. %0.3
Function
Origin
Isononyl IsononanoateAn ester of a branched fatty acid with a branched fatty alcohol. It is an easily spreadable emollient that has a silky, dry, non-greasy feel on the skin.
Methyl Glucose Sesquistearate
Est. %0.3
Function
Origin
Methyl Glucose SesquistearateAn ultra gentle emulsifier that can be used in many products to blend oils and water together while providing a light film on the skin.
Methyl Methacrylate Crosspolymer
Est. %0.3
Function
Origin
Methyl Methacrylate CrosspolymerA synthetic ingredient that is used for bulking, film-forming, and controlling viscosity. It can absorb large amounts of water and oil and creates a network for other ingredients to live in.
Sclerotium Gum
Est. %0.3
Function
Origin
Sclerotium GumA thickener with a silky, velvety feel that many manufacturers use as an alternative to silicones.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Sodium Carbomer
Est. %0.3
Function
Origin
Sodium CarbomerLike Carbomer, only pre-reacted so that no neutralization is required. Carbomer based gels are clear and have a non-sticky smooth feel. Many high end cosmetics will use carbomers as part of their formula to build body without making a product feel heavy.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Ammonium Polyacryloyldimethyl Taurate
Est. %0.3
Function
Origin
Ammonium Polyacryloyldimethyl TaurateAn emulsion stabilizer and thickener with gelling properties. The products containing this ingredient frequently feature lightweight and refreshing aesthetics upon application to the skin.
Succinoglycan
Est. %0.3
Function
Origin
Succinoglycan
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Trisodium EDTA
Est. %0.3
Function
Origin
Trisodium EDTAA chelating agent designed to encapsulate potentially harmful heavy metal ions that enter the formula through the water source. Once encapsulated, these heavy metal ions become inert.