Physicians Formula 24-Karat Gold Collagen Lip Serum Review

Physicians Formula 24-Karat Gold Collagen Lip Serum
7.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
4.4 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Ingredients

Physicians Formula 24-Karat Gold Collagen Lip Serum Ingredients

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Full Ingredient List (INCI):

Water, Glycerin, Niacinamide, Sclerocarya Birrea Seed Oil, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Theobroma Cacao (Cocoa) Seed Butter, Lecithin, Caesalpinia Spinosa Gum, Cichorium Intybus (Chicory) Root Oligosaccharides, Leuconostoc/Radish Root Ferment Filtrate, Gold (CI 77480), Cocoyl Hydrolyzed Collagen, Gluconolactone, Sodium Benzoate
Review

Does Physicians Formula 24-Karat Gold Collagen Lip Serum Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Physicians Formula 24-Karat Gold Collagen Lip Serum has to offer:
 
✅ Significant moisturizing. It has a moisturizing rating of 7.2 out of 10.
✅ Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Physicians Formula 24-Karat Gold Collagen Lip Serum is effective in minimizing wrinkles.
✅ Antioxidant protection

  

Key Benefits of Physicians Formula 24-Karat Gold Collagen Lip Serum

 
These are the key benefits you can expect from using Physicians Formula 24-Karat Gold Collagen Lip Serum:
 

🔵🔵 Perfect Moisturizer for Normal to Dry Skin with a Balanced Texture, Neither Too Light nor Too Heavy

According to CreamScan analysis, Physicians Formula 24-Karat Gold Collagen Lip Serum is highly moisturizing, with a moisturizing rating of 7.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈6.0%) and Niacinamide (est. ≈4.0%), and a moderate occlusivity of 4.4 out of 10, mainly due to the high content of Sclerocarya Birrea Seed Oil (est. ≈3.0%) and Tocopherol (est. ≈2.0%).

This type of moisturizer is ideal for people with normal skin who want maximum hydration in a formula with a balanced texture - neither too light nor too heavy. It combines a very high concentration of humectants with a moderate amount of occlusive ingredients to deliver effective dual-action moisturizing for normal skin.

This product may also be a good choice for people with normal to dry skin for daily hydration.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, Physicians Formula 24-Karat Gold Collagen Lip Serum has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈4.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Physicians Formula 24-Karat Gold Collagen Lip Serum also contains Gluconolactone, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Gluconolactone provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Gluconolactone may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Physicians Formula 24-Karat Gold Collagen Lip Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈4.0%) and Tocopherol (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of Physicians Formula 24-Karat Gold Collagen Lip Serum

 
Here’s an overview of the pros and cons of Physicians Formula 24-Karat Gold Collagen Lip Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ Perfect for moisturizing normal skin
Balanced texture, neither too light nor too heavy
Delivers signficant anti-wrinkle efficacy thanks to Niacinamide
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: Physicians Formula 24-Karat Gold Collagen Lip Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Physicians Formula 24-Karat Gold Collagen Lip Serum
 is specifically effective in treating wrinkles, containing ingredients with solid, robust evidence of anti-wrinkle efficacy.
 

It’s an ideal moisturizer for normal skin, combining a very high concentration of humectants with a significant amount of occlusive ingredients in a balanced texture - neither too light nor too heavy.

With its high antioxidant content, Physicians Formula 24-Karat Gold Collagen Lip Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
80
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Niacinamide
Function:
Origin:
Sclerocarya Birrea Seed Oil
Function:
Origin:
Tocopherol
Function:
Origin:
Helianthus Annuus (Sunflower) Seed Oil
Function:
Origin:
Copernicia Cerifera (Carnauba) Wax
Function:
Origin:
Theobroma Cacao (Cocoa) Seed Butter
Function:
Origin:
Lecithin
Function:
Origin:
Caesalpinia Spinosa Gum
Function:
Origin:
Cichorium Intybus (Chicory) Root Oligosaccharides
Function:
Origin:
Leuconostoc/Radish Root Ferment Filtrate
Function:
Origin:
Gold (CI 77480)
Function:
Origin:
Cocoyl Hydrolyzed Collagen
Function:
Origin:
Gluconolactone
Function:
Origin:
Sodium Benzoate
Function:
Origin:

Ratings

All humectants
10.6
6
4
0.3
0.3
Benchmark
10
All occlusives
8.8
3.0
2.0
1.5
1.3
1.0
Benchmark
20
Moisturizing rating
7.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.6 10
10.0
6
4
0.3
0.3
Occlusivity All occlusives 8.8 20
4.4
3.0
2.0
1.5
1.3
1.0
Moisturizing rating
7.2
Ingredient Est. % Benchmark Humectancy
6
4
0.3
0.3
All humectants 10.6 10
10
All humectants
10.6
6
4
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
3
2
1.5
1.3
1
All occlusives 8.8 20
4.4
All occlusives
8.8
3.0
2.0
1.5
1.3
1.0
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 4 6
n/a
- 0.3 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
4
Gluconolactone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
4
2
All antioxidants 6 3 Rich in antioxidants
All antioxidants
6
Niacinamide
4
Tocopherol
2
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
All soothing 4 5 No
All soothing
4
4
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Niacinamide
Est. %4
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Sclerocarya Birrea Seed Oil
Est. %3
Function
Origin
Sclerocarya Birrea Seed OilA famous but not well enough researched emollient fatty oil from the seeds of Marula fruits. It contains fatty acids and a lot of antioxidant and emollient phytosterols.
Tocopherol
Est. %2
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Helianthus Annuus (Sunflower) Seed Oil
Est. %1.5
Function
Origin
Helianthus Annuus (Sunflower) Seed OilA fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Copernicia Cerifera (Carnauba) Wax
Est. %1.3
Function
Origin
Copernicia Cerifera (Carnauba) WaxObtained from the leaves of Carnauba wax palm, this occlusive, emollient, and film-forming wax is commonly used in lip products. It is comprised mainly of various wax esters and is one of the hardest and most resistant plant waxes.
Theobroma Cacao (Cocoa) Seed Butter
Est. %1
Function
Origin
Theobroma Cacao (Cocoa) Seed ButterAlso known as cocoa seed butter, it is a popular emollient and occlusive moisturizer. Skincare products with cocoa butter as their main ingredient have a sweet, chocolatey scent. Cocoa butter is listed as a common comedogenic ingredient by acne.org.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Caesalpinia Spinosa Gum
Est. %0.3
Function
Origin
Caesalpinia Spinosa GumA plant-based formula helper also known as Tara gum that contains thickening galactomannans (polysaccharides).
Cichorium Intybus (Chicory) Root Oligosaccharides
Est. %0.3
Function
Origin
Cichorium Intybus (Chicory) Root Oligosaccharides
Leuconostoc/Radish Root Ferment Filtrate
Est. %0.3
Function
Origin
Leuconostoc/Radish Root Ferment FiltrateA biotechnological fermentation ingredient that is created by feeding radish root to Leuconostoc kimchii. It allegedly contains organic acids and a mixture of peptides known as bacteriocins – which have antimicrobial activity.
Gold (CI 77480)
Est. %0.3
Function
Origin
Gold (CI 77480)

A colorant used in skincare, typically processed into fine particles for uniform dispersion. Its luxurious hue enhances product aesthetics, while its role as a slip and surface modifier improves texture and application. Despite touted anti-aging benefits, definitive scientific evidence is lacking.

Cocoyl Hydrolyzed Collagen
Est. %0.3
Function
Origin
Cocoyl Hydrolyzed Collagen
Gluconolactone
Est. %0.3
Function
Origin
GluconolactoneA PHA derived from glucose. It has exfoliating and humectant properties and acts as a penetration enhancer for other ingredients. It has also been shown to assist in the treatment of acne and the prevention of photoaging.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.