NeoStrata High Potency Cream Review

NeoStrata High Potency Cream
5.0
/ 10
Moisturizing
9.4 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
1.5Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does NeoStrata High Potency Cream Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what NeoStrata High Potency Cream has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
✅ Slight anti-wrinkle effect: NeoStrata High Potency Cream has an anti-wrinkle rating of 1.5 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

  

Key Benefits of NeoStrata High Potency Cream

 
These are the key benefits you can expect from using NeoStrata High Potency Cream:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, NeoStrata High Potency Cream is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a very high humectancy of 9.4 out of 10, primarily due to the high content of Arginine (est. ≈6.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, NeoStrata High Potency Cream has a slight anti-wrinkle rating of 1.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Glycolic Acid (est. ≈18.0%),
 a highly effective ingredient in peelings but with moderate anti-wrinkle efficacy in leave-on skincare products, as supported by a single clinical study. This study, involving 72 participants (Thibault et al.), demonstrated that a lotion with 5% GA reduced the fine wrinkling score by 6% after 34 days of use, compared to a vehicle (the same formulation without GA).
 
Among others, NeoStrata High Potency Cream also contains Lactobionic Acid, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Lactobionic Acid provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Lactobionic Acid may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: NeoStrata High Potency Cream

 
CreamScan AI identified a few things to consider before adding NeoStrata High Potency Cream to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Glycolic Acid

This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. Its action works by removing dead skin cells, revealing new, more delicate skin that is particularly vulnerable to sun damage.

As a result, using products with glycolic acid, regardless of concentration, may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To counteract this increased sun sensitivity, apply a broad-spectrum sunscreen with at least SPF 30 daily to protect your skin during glycolic acid treatment.

❗️Please always check the manufacturer's instructions for using the product, either on their website or product label.

Pros & Cons of NeoStrata High Potency Cream

 
Here’s an overview of the pros and cons of NeoStrata High Potency Cream to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Provides slight anti-wrinkle efficacy
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to glycolic acid
   

Summary: NeoStrata High Potency Cream

 
Based on the ingredient list analysis, CreamScan AI suggests that NeoStrata High Potency Cream
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
NeoStrata High Potency Cream contains ingredients with proven evidence of anti-wrinkle efficacy that may offer a slight anti-wrinkle effect. As a result, you can expect a positive, though relatively minimal, impact on wrinkles.
 
 
That said, there are some things about NeoStrata High Potency Cream worth noting.
 
This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. However, glycolic acid - regardless of concentration - can increase skin sensitivity, making it more prone to sunburn or irritation when exposed to UV rays. Therefore, it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 during glycolic acid treatment.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
60
18
6
2
1.9
1.8
1.7
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycolic Acid
Function:
Origin:
Arginine
Function:
Origin:
Ammonium Hydroxide
Function:
Origin:
Propylene Glycol
Function:
Origin:
Isostearic Acid
Function:
Origin:
PEG-100 Stearate
Function:
Origin:
Lactobionic Acid
Function:
Origin:
Isododecane
Function:
Origin:
Isohexadecane
Function:
Origin:
Palmitic Acid
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Stearic Acid
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Sorbitan Stearate
Function:
Origin:
Methylglucamine
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Dimethicone
Function:
Origin:
Bisabolol
Function:
Origin:
Myristic Acid
Function:
Origin:
Xanthan Gum
Function:
Origin:
Polyacrylate-1 Crosspolymer
Function:
Origin:
Disodium EDTA
Function:
Origin:
Sodium Sulfite
Function:
Origin:
Sodium Bisulfite
Function:
Origin:
BHT
Function:
Origin:
Propylparaben
Function:
Origin:
Methylparaben
Function:
Origin:

Ratings

All humectants
9.4
6
1.9
1.5
Benchmark
10
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.4 10
9.4
6
1.9
1.5
Occlusivity All occlusives 1.2 20
0.6
0.3
0.3
0.3
0.3
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
1.9
1.5
All humectants 9.4 10
9.4
All humectants
9.4
6
1.9
1.5
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
0.3
All occlusives 1.2 20
0.6
All occlusives
1.2
0.3
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
1.5 /10 5 18 1.5
n/a
- 1.5 -
Total
1.5
Glycolic Acid
1.5
Ingredient anti-wrinkle power
1.5 /10
when present at, %
5
in this formula, est. %
18
Lactobionic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Anti-wrinkle rating
1.5
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
All antioxidants 1.2 3 No
All antioxidants
1.2
Tocopheryl Acetate
0.3
Sodium Sulfite
0.3
Sodium Bisulfite
0.3
BHT
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
All soothing 0.3 5 No
All soothing
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %60
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycolic Acid
Est. %18
Function
Origin
Glycolic Acid

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy, though it is less effective in leave-on products like creams and serums.

Arginine
Est. %6
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Ammonium Hydroxide
Est. %2
Function
Origin
Ammonium HydroxideA weakly basic ingredient that can adjust pH to a higher level.
Propylene Glycol
Est. %1.9
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Isostearic Acid
Est. %1.8
Function
Origin
Isostearic AcidA saturated fatty acid used to mix oil and water and to remove dirt from the skin's surface. Isostearic acid is listed among common comedogenic ingredients by acne.org.
PEG-100 Stearate
Est. %1.7
Function
Origin
PEG-100 StearateThis surfactant is more specifically classified as an emulsifier that produces oil-in-water emulsions. PEG-100 stearate can also be used as a cleansing agent.
Lactobionic Acid
Est. %1.5
Function
Origin
Lactobionic AcidA very gentle and non-irritating PHA derived from lactic acid. It has exfoliating and humectant properties and can improve skin elasticity.
Isododecane
Est. %1.3
Function
Origin
IsododecaneAn emollient derived from petroleum with high spreadability. It is often used as a replacement for oils and silicones because it leaves no residue behind on the skin. When a product is labeled as “oil-free” it may contain isododecane instead of heavier oils.
Isohexadecane
Est. %1
Function
Origin
IsohexadecaneA clear, colorless liquid that is commonly used as an emollient. It is made up of pure hydrocarbons and leaves a dry feeling on the skin upon application. It also increases the spreadability of a product.
Palmitic Acid
Est. %0.3
Function
Origin
Palmitic AcidA saturated fatty acid used in skincare as a strongly occlusive moisturizer and barrier repairing, emollient ingredient. It is a waxy-looking, white solid. Palmitic acid can be commonly found in animal and vegetable fats, notably palm oil.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Stearic Acid
Est. %0.3
Function
Origin
Stearic AcidA saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Cetyl Alcohol
Est. %0.3
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Sorbitan Stearate
Est. %0.3
Function
Origin
Sorbitan StearateA vegetable-derived ingredient most commonly used as an emulsifier to stabilize water and oil mixtures.
Methylglucamine
Est. %0.3
Function
Origin
Methylglucamine
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Dimethicone
Est. %0.3
Function
Origin
DimethiconeThe most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Bisabolol
Est. %0.3
Function
Origin
Bisabolol

An anti-inflammatory compound found naturally in German chamomile essential oil. It has a pleasant, sweet, and floral scent. Bisabolol also has soothing and anti-inflammatory properties but can cause an allergic reaction in more sensitive individuals.

Myristic Acid
Est. %0.3
Function
Origin
Myristic AcidA common fatty acid found in various vegetable oils, most notably palm and coconut oil. It is a strongly occlusive moisturizing, emollient, and emulsifying ingredient.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Polyacrylate-1 Crosspolymer
Est. %0.3
Function
Origin
Polyacrylate-1 Crosspolymer
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Sodium Sulfite
Est. %0.3
Function
Origin
Sodium SulfiteAn inorganic salt that defends against oxidation.
Sodium Bisulfite
Est. %0.3
Function
Origin
Sodium BisulfiteAn inorganic salt that kills bacteria and protects against oxidation.
BHT
Est. %0.3
Function
Origin
BHTAn antioxidant ingredient that naturally occurs in green algae and some bacteria or fungi but, for commercial use, is created synthetically. BHT is also used occasionally as a fragrance, where it presents a sweet, camphor-like odor.
Propylparaben
Est. %0.3
Function
Origin
PropylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.
Methylparaben
Est. %0.3
Function
Origin
MethylparabenA preservative that keeps a product unspoiled. There has been a lot of controversy surrounding parabens, although the concentrations found in cosmetic formulations are generally considered to be safe.