Neocutis BIO SERUM FIRM Rejuvenating Growth Factor and Peptide Treatment

Neocutis BIO SERUM FIRM Rejuvenating Growth Factor and Peptide Treatment
6.6
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
3.2 Occlusivity icon Occlusivity
Rich
in Antioxidants

Review

Results you may expect from using Neocutis BIO SERUM FIRM Rejuvenating Growth Factor and Peptide Treatment:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using Neocutis BIO SERUM FIRM Rejuvenating Growth Factor and Peptide Treatment:

  • Significant moisturizing. It has a moisturizing rating of 6.6 out of 10.
  • Antioxidant protection.

How moisturizing is it?

Highly moisturizing: Neocutis BIO SERUM FIRM Rejuvenating Growth Factor and Peptide Treatment has a moisturizing rating of 6.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a maximum humectancy of 10 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈6.0%), and a moderate occlusivity of 3.2 out of 10, mainly due to the high content of Caprylic/Capric Triglyceride (est. ≈4.0%) and Squalane (est. ≈2.0%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, Neocutis BIO SERUM FIRM Rejuvenating Growth Factor and Peptide Treatment has a zero anti-wrinkle rating.

It contains some ingredients marketed as effective in reducing wrinkles, specifically Aminopropyl Ascorbyl Phosphate, Tetrapeptide-21, Acetyl Glucosamine, and Trifluoroacetyl Tripeptide-2. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that Neocutis BIO SERUM FIRM Rejuvenating Growth Factor and Peptide Treatment is rich (> 3%) in antioxidants, specifically Aminopropyl Ascorbyl Phosphate (est. ≈1.5%), Sodium Hyaluronate (est. ≈1.3%), Hydrolyzed Sodium Hyaluronate (est. ≈1.0%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
75
Water
6
Glycerin
4
Caprylic/Capric Triglyceride
3
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
2
Squalane
1.5
Aminopropyl Ascorbyl Phosphate
1.3
Sodium Hyaluronate
1
Hydrolyzed Sodium Hyaluronate
0.3
Cutaneous Lysate
0.3
Tetrapeptide-21
0.3
Palmitoyl Tripeptide-1 Acetate
0.3
Butylene Glycol
0.3
Ethylhexylglycerin
0.3
Pullulan
0.3
Acetyl Glucosamine
0.3
Ethylene/Acrylic Acid Copolymer
0.3
Polysorbate 60
0.3
Proline
0.3
Arginine
0.3
Glycine
0.3
Glutamine
0.3
Chlorphenesin
0.3
Nannochloropsis Oculata Extract
0.3
Capryloyl Carnosine
0.3
Poloxamer 338
0.3
Silica
0.3
Trifluoroacetyl Tripeptide-2
0.3
Dextran
0.3
Sorbitan Isostearate
0.3
Potassium Sorbate
0.3
Sodium Benzoate
0.3
Tocopherol
0.3
Disodium EDTA
0.3
Sodium Hydroxide
0.3
Phenoxyethanol
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Function:
Origin:
Squalane
Function:
Origin:
Aminopropyl Ascorbyl Phosphate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Hydrolyzed Sodium Hyaluronate
Function:
Origin:
Cutaneous Lysate
Function:
Origin:
Tetrapeptide-21
Function:
Origin:
Palmitoyl Tripeptide-1 Acetate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Pullulan
Function:
Origin:
Acetyl Glucosamine
Function:
Origin:
Ethylene/Acrylic Acid Copolymer
Function:
Origin:
Polysorbate 60
Function:
Origin:
Proline
Function:
Origin:
Arginine
Function:
Origin:
Glycine
Function:
Origin:
Glutamine
Function:
Origin:
Chlorphenesin
Function:
Origin:
Nannochloropsis Oculata Extract
Function:
Origin:
Capryloyl Carnosine
Function:
Origin:
Poloxamer 338
Function:
Origin:
Silica
Function:
Origin:
Trifluoroacetyl Tripeptide-2
Function:
Origin:
Dextran
Function:
Origin:
Sorbitan Isostearate
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Tocopherol
Function:
Origin:
Disodium EDTA
Function:
Origin:
Sodium Hydroxide
Function:
Origin:
Phenoxyethanol
Function:
Origin:

Ratings

All humectants
10.4
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
6.3
4.0
2.0
0.3
Benchmark
20
Moisturizing rating
6.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.4 10
10.0
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 6.3 20
3.2
4.0
2.0
0.3
Moisturizing rating
6.6
Ingredient Est. % Benchmark Humectancy
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 10.4 10
10
All humectants
10.4
6
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
4
2
0.3
All occlusives 6.3 20
3.2
All occlusives
6.3
4.0
2.0
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 1.5 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Aminopropyl Ascorbyl Phosphate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Tetrapeptide-21
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Glucosamine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Trifluoroacetyl Tripeptide-2
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1.3
1
0.3
All antioxidants 4.1 3 Rich in antioxidants
All antioxidants
4.1
Aminopropyl Ascorbyl Phosphate
1.5
Sodium Hyaluronate
1.3
Hydrolyzed Sodium Hyaluronate
1
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
None
All soothing 0 5 No
All soothing
0
None
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Caprylic/Capric Triglyceride
Est. %4
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Est. %3
Function
Origin
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate CopolymerAn emulsion stabilizer and thickener that helps to create a pleasant, satiny, and light formula texture. It works by forming a gel-like network within water or oil, which both stabilizes other ingredients and produces a thickening effect.
Squalane
Est. %2
Function
Origin
SqualaneAn occlusive moisturizing and emollient compound that forms part of the skin’s sebum. The main source of squalane had always been shark liver. Now, however, it is manufactured synthetically or derived from plant oils, such as olive and peanut oil.
Aminopropyl Ascorbyl Phosphate
Est. %1.5
Function
Origin
Aminopropyl Ascorbyl PhosphateOne of the most recent vitamin C derivatives. Although the manufacturer claims it has all the powers of ascorbic acid (e.g., it is collagen-boosting and able to treat hyperpigmentation), this has not been proven in scientific studies.
Sodium Hyaluronate
Est. %1.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Hydrolyzed Sodium Hyaluronate
Est. %1
Function
Origin
Hydrolyzed Sodium HyaluronateA very small-molecule version of regular sodium hyaluronate. It is a powerful humectant skin-identical ingredient that absorbs into the skin and offers plumping, smoothing, and anti-wrinkle effects.
Cutaneous Lysate
Est. %0.3
Function
Origin
Cutaneous LysateDescription is coming soon
Tetrapeptide-21
Est. %0.3
Function
Origin
Tetrapeptide-21

A synthetically made peptide (similar to skin proteins) designed to increase the synthesis of collagen, HA, and fibronectin. It has been clinically proven to improve skin quality and elasticity, as well as the appearance of wrinkles.

Palmitoyl Tripeptide-1 Acetate
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1 AcetateDescription is coming soon
Butylene Glycol
Est. %0.3
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Pullulan
Est. %0.3
Function
Origin
PullulanDescription is coming soon
Acetyl Glucosamine
Est. %0.3
Function
Origin
Acetyl GlucosamineA body-natural amino-saccharide used in skincare as an anti-pigment ingredient. Some other benefits of acetyl glucosamine include decreased skin flakiness, improved wound healing, and even a slight reduction in facial wrinkles.
Ethylene/Acrylic Acid Copolymer
Est. %0.3
Function
Origin
Ethylene/Acrylic Acid CopolymerDescription is coming soon
Polysorbate 60
Est. %0.3
Function
Origin
Polysorbate 60An ester based on sorbitan. It is good for emulsifying water and oils together – specifically making oil-in-water emulsions. Polysorbate 60 is also said to give a product a notable fragrance.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Arginine
Est. %0.3
Function
Origin
ArginineA humectant amino acid used to attract water to the skin’s surface. It is a part of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Arginine can also be used as a pH adjuster.
Glycine
Est. %0.3
Function
Origin
GlycineA humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.
Glutamine
Est. %0.3
Function
Origin
GlutamineA humectant moisturizing amino acid that, aside from attracting water to the skin’s surface, can also soothe allergic itching and reduce the signs of inflammation.
Chlorphenesin
Est. %0.3
Function
Origin
ChlorphenesinA preservative and broad-spectrum antimicrobial agent that protects products from a wide range of bacteria and fungi.
Nannochloropsis Oculata Extract
Est. %0.3
Function
Origin
Nannochloropsis Oculata ExtractDescription is coming soon
Capryloyl Carnosine
Est. %0.3
Function
Origin
Capryloyl CarnosineDescription is coming soon
Poloxamer 338
Est. %0.3
Function
Origin
Poloxamer 338Description is coming soon
Silica
Est. %0.3
Function
Origin
SilicaA widely used cosmetic ingredient with the same chemical composition as the sand found on beaches. A common function of silica is its ability to control viscosity. In certain chemical forms, it can effectively thicken cream-style products.
Trifluoroacetyl Tripeptide-2
Est. %0.3
Function
Origin
Trifluoroacetyl Tripeptide-2

A synthetically made peptide that was shown to slow down the degradation of elastin in the skin. It is said to be able to reduce sagging and wrinkles in different parts of the face, although this has not been well researched yet.

Dextran
Est. %0.3
Function
Origin
DextranA naturally derived sucrose metabolite that thickens water and bulks emulsions.
Sorbitan Isostearate
Est. %0.3
Function
Origin
Sorbitan IsostearateA mild yet powerful emulsifier primarily utilized to produce water-in-oil emulsions. It helps to create a particularly rich and substantial emulsion.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Sodium Hydroxide
Est. %0.3
Function
Origin
Sodium Hydroxide

An ingredient that is able to bring the pH of a product up, thereby making it less harsh on the skin.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.