Mixsoon Premium Bifida Serum | Unbiased Skincare Efficacy Review by AI

Review

Does Mixsoon Premium Bifida Serum Work?

According to CreamScan AI's analysis of the ingredient list, here’s what Mixsoon Premium Bifida Serum has to offer:

Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.

Slight anti-wrinkle effect: Mixsoon Premium Bifida Serum has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

Key Benefits of Mixsoon Premium Bifida Serum

These are the key benefits you can expect from using Mixsoon Premium Bifida Serum:

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Mixsoon Premium Bifida Serum is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%), Bifida Ferment Extract (est. ≈4.0%) and Glycerin (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, Mixsoon Premium Bifida Serum has a slight anti-wrinkle rating of 0.4 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Ectoin (est. ≈0.3%),

an amino acid-derived ingredient with moderate but proven anti-wrinkle efficacy. A single clinical study involving 104 participants (Heinrich et al.) confirmed that a cream containing 2% ectoin reduced the average wrinkle width by 7% after 4 weeks of use, compared to the same formulation without ectoin (vehicle).

Among others, Mixsoon Premium Bifida Serum also contains Adenosine, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Adenosine provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Mixsoon Premium Bifida Serum

CreamScan AI identified a few things to consider before adding Mixsoon Premium Bifida Serum to your skincare routine:

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Mixsoon Premium Bifida Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Mixsoon Premium Bifida Serum

Here’s an overview of the pros and cons of Mixsoon Premium Bifida Serum to help you decide if it’s the right choice for your skincare routine:

Pros:

When used alone: Provides humectant-rich moisturizing ideal for oily skin
As part of a routine: A humectant moisturizing boost, beneficial for any skin type
Lightweight texture

Provides slight anti-wrinkle efficacy

Cons:

Needs to be paired with occlusives to seal in humectants if used as a standalone moisturizer

Fragrance
Formula helpers

Other

Est. % The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more	Ingredient	Origin	Functions
80	Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients. Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water.	Formula helper Solvent – a liquid that dissolves other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients.
6	Butylene Glycol A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups. Butylene Glycol A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria. Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria.	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product. Formula helper Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product.
4	Bifida Ferment Extract Bifida Ferment Extract	Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
3	Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective. Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Formula helper Denaturant – turns alcohol undrinkable. Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product. Formula helper Denaturant – turns alcohol undrinkable. Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product.
2	Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn. Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Barrier Repair, Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Barrier Repair, Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Formula helper Antistatic – reduces electric charge buildup. Solvent – a liquid that dissolves other ingredients. Formula helper Antistatic – reduces electric charge buildup. Solvent – a liquid that dissolves other ingredients.
1.5	Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties. Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.	Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging.
1.3	Betaine An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin. Betaine An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Formula helper Antistatic – reduces electric charge buildup. Viscosity controlling – changes the thickness of a product. Formula helper Antistatic – reduces electric charge buildup. Viscosity controlling – changes the thickness of a product.
1	Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind. Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.
0.3	Glycine A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties. Glycine A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Formula helper Antistatic – reduces electric charge buildup. pH adjuster – alters the pH level of a formula. Formula helper Antistatic – reduces electric charge buildup. pH adjuster – alters the pH level of a formula.
0.3	Ectoin An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy. Ectoin An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.	Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Formula helper pH adjuster – alters the pH level of a formula. Formula helper pH adjuster – alters the pH level of a formula.
0.3	Ceramide NP Also known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides. Ceramide NP Also known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier.
0.3	Oligopeptide-127 rh-Oligopeptide-1 Oligopeptide-127 rh-Oligopeptide-1		Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients.

Water

Function:

Origin:

Butylene Glycol

Function:

Origin:

Bifida Ferment Extract

Function:

Origin:

Glycerin

Function:

Origin:

Panthenol

Function:

Origin:

1.5

Hydrolyzed Hyaluronic Acid

Function:

Origin:

1.3

Betaine

Function:

Origin:

Adenosine

Function:

Origin:

0.3

Glycine

Function:

Origin:

0.3

Ectoin

Function:

Origin:

0.3

Ceramide NP

Function:

Origin:

0.3

Oligopeptide-127 rh-Oligopeptide-1

Function:

Origin:

Ratings

Butylene Glycol

Bifida Ferment Extract

Glycerin

Panthenol

Hydrolyzed Hyaluronic Acid

1.5

Betaine

1.3

Glycine

0.3

Benchmark

None

Benchmark

Moisturizing rating

5.0

Ingredient		Est. %	Benchmark Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity. Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity.	Raiting
Humectancy	All humectants	18.1	10	10.0
	Butylene Glycol A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups. Butylene Glycol A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.	6
	Bifida Ferment Extract Bifida Ferment Extract	4
	Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective. Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.	3
	Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn. Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.	2
	Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties. Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.	1.5
	Betaine An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin. Betaine An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.	1.3
	Glycine A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties. Glycine A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.	0.3
Occlusivity	All occlusives	0.0	20	0.0
	None
Moisturizing rating				5.0

Ingredient	Est. %	Benchmark According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more. According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more.	Humectancy
Butylene Glycol A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups. Butylene Glycol A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.	6
Bifida Ferment Extract Bifida Ferment Extract	4
Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective. Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.	3
Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn. Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.	2
Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties. Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.	1.5
Betaine An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin. Betaine An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.	1.3
Glycine A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties. Glycine A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.	0.3
All humectants	18.1	10	10

Butylene Glycol

Bifida Ferment Extract

Glycerin

Panthenol

Hydrolyzed Hyaluronic Acid

1.5

Betaine

1.3

Glycine

0.3

Benchmark

Ingredient	Est. %	Benchmark The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled). The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled).	Occlusivity
None
All occlusives	0.0	20	0.0

None

Benchmark

Ingredient	Ingredient anti-wrinkle power Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account. Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account.	when present at, %	in this formula est. %	Rating
Ectoin An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy. Ectoin An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.	2.5 /10	2	0.3	0.4
Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind. Adenosine A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.	n/a This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient do not contribute to the anti-wrinkle rating. This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient do not contribute to the anti-wrinkle rating.	-	1	-
Total				0.4

Ectoin

0.4

Ingredient anti-wrinkle power

2.5 /10

when present at, %

in this formula, est. %

0.3

Adenosine

Ingredient anti-wrinkle power

n/a

when present at, %

in this formula, est. %

Anti-wrinkle rating

0.4

Ingredient	Est. %	Benchmark It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants. It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants.	Rich in Antioxidants
Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties. Hydrolyzed Hyaluronic Acid A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.	1.5
All antioxidants	1.5	3	No

Hydrolyzed Hyaluronic Acid

1.5

Benchmark

Ingredient	Est. %	Benchmark The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%. The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%.	Rich in Soothing
Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn. Panthenol A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.	2
Ectoin An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy. Ectoin An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.	0.3
All soothing	2.3	5	No

Panthenol

Ectoin

0.3

Benchmark

Ingredients explained

Water
Est. %	80
Function	Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water.

The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.

Butylene Glycol
Est. %	6
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Solvent, Solvent – a liquid that dissolves other ingredients. Solvent, Solvent – a liquid that dissolves other ingredients. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria. Petroleum Ingredients derived from petroleum, also called crude oil. Crude oil deposits were obtained from the remains of ancient organisms, such as plants, algae, and bacteria.

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Bifida Ferment Extract
Est. %	4
Function	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid).
Origin	Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified.

Glycerin
Est. %	3
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Denaturant, Denaturant – turns alcohol undrinkable. Denaturant, Denaturant – turns alcohol undrinkable. Solvent, Solvent – a liquid that dissolves other ingredients. Solvent, Solvent – a liquid that dissolves other ingredients. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Panthenol
Est. %	2
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Barrier Repair, Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Barrier Repair, Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Antistatic, Antistatic – reduces electric charge buildup. Antistatic, Antistatic – reduces electric charge buildup. Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.

Hydrolyzed Hyaluronic Acid
Est. %	1.5
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging.
Origin	Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

A smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.

Betaine
Est. %	1.3
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antistatic, Antistatic – reduces electric charge buildup. Antistatic, Antistatic – reduces electric charge buildup. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

An ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.

Adenosine
Est. %	1
Function	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Glycine
Est. %	0.3
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antistatic, Antistatic – reduces electric charge buildup. Antistatic, Antistatic – reduces electric charge buildup. pH Adjuster pH adjuster – alters the pH level of a formula. pH Adjuster pH adjuster – alters the pH level of a formula.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A humectant moisturizing amino acid that is a part of skin's Natural Moisturizing Factor. Some recent studies suggest that it may have barrier repair properties.

Ectoin
Est. %	0.3
Function	Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle, Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. pH Adjuster pH adjuster – alters the pH level of a formula. pH Adjuster pH adjuster – alters the pH level of a formula.
Origin	Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Biotech, The biotech origin of the ingredient implies that it was made in a lab using cultured microorganisms (bacteria or fungi) and a substrate (e.g. through the fermentation process), and then extracted and/or purified. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

An amino acid-derived ingredient with average, yet proven by one study, anti-wrinkle efficacy.

Ceramide NP
Est. %	0.3
Function	Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

Also known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.

Oligopeptide-127 rh-Oligopeptide-1
Est. %	0.3
Function	Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients.
Origin