ma:nyo Bifida Ampoule Mist

ma:nyo Bifida Ampoule Mist
5.0
/ 10
Moisturizing
9.9 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers

Review

Does ma:nyo Bifida Ampoule Mist work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using ma:nyo Bifida Ampoule Mist:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Soothing: ma:nyo Bifida Ampoule Mist contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, ma:nyo Bifida Ampoule Mist is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a very high humectancy of 9.9 out of 10, primarily due to the high content of Butylene Glycol (est. ≈3.0%) and Glycerin (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Questionable anti-wrinkle efficacy

According to CreamScan analysis, ma:nyo Bifida Ampoule Mist has a zero anti-wrinkle rating.

It contains some ingredients often marketed as effective in reducing wrinkles, specifically Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Camellia Sinensis Leaf Extract, Caffeine, and Adenosine. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that ma:nyo Bifida Ampoule Mist is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈1.5%), Lactobacillus (est. ≈1.3%), Phellinus Linteus Extract (est. ≈1.0%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing and calming potential

Based on the ingredient list analysis, ma:nyo Bifida Ampoule Mist is rich (> 5%) in soothing ingredients, particularly Bifida Ferment Lysate (est. ≈20.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
60
20
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Paeonia Lactiflora Root Extract
Function:
Origin:
Bifida Ferment Lysate
Function:
Origin:
Lactobacillus/Pumpkin Fruit Ferment Filtrate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Lactobacillus
Function:
Origin:
Phellinus Linteus Extract
Function:
Origin:
Acetyl Hexapeptide-8
Function:
Origin:
Aureobasidium Pullulans Ferment
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Glycyrrhiza Glabra (Licorice) Root Extract
Function:
Origin:
Trametes Versicolor Extract
Function:
Origin:
Allantoin
Function:
Origin:
Panthenol
Function:
Origin:
Physalis Alkekengi Fruit Extract
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Panax Ginseng Root Extract
Function:
Origin:
Forsythia Suspensa Fruit Extract
Function:
Origin:
Dioscorea Oppositifolia (Wild Yam) Root Extract
Function:
Origin:
Caffeine
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Scutellaria Baicalensis Root Extract
Function:
Origin:
Illicium Verum (Anise) Fruit Extract
Function:
Origin:
Adenosine
Function:
Origin:

Ratings

All humectants
9.9
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.9 10
9.9
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 9.9 10
9.9
All humectants
9.9
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Acetyl Hexapeptide-8
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Caffeine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.6 3 Rich in antioxidants
All antioxidants
5.6
Sodium Hyaluronate
1.5
Lactobacillus
1.3
Phellinus Linteus Extract
1
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Panax Ginseng Root Extract
0.3
Forsythia Suspensa Fruit Extract
0.3
Caffeine
0.3
Scutellaria Baicalensis Root Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
20
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 21.8 5 Rich in soothing
All soothing
21.8
20
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Paeonia Lactiflora Root Extract
Est. %60
Function
Origin
Paeonia Lactiflora Root ExtractAn extract derived from the roots of the garden peony. It has been suggested that this ingredient has anti-pigment activity.
Bifida Ferment Lysate
Est. %20
Function
Origin
Bifida Ferment LysateA mixture of probiotic bacteria. According to the patent holder, it contains enzymes that are able to repair damaged DNA in skin cells. A single study confirms that it is able to reduce skin sensitivity.
Lactobacillus/Pumpkin Fruit Ferment Filtrate
Est. %4
Function
Origin
Lactobacillus/Pumpkin Fruit Ferment Filtrate
Butylene Glycol
Est. %3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycerin
Est. %2
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Sodium Hyaluronate
Est. %1.5
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Lactobacillus
Est. %1.3
Function
Origin
LactobacillusA genus of probiotic bacteria. Lactobacillus bacteria are part of the human microflora and their ferment products contain antioxidants.
Phellinus Linteus Extract
Est. %1
Function
Origin
Phellinus Linteus Extract
Acetyl Hexapeptide-8
Est. %0.3
Function
Origin
Acetyl Hexapeptide-8

A small synthetic peptide that is thought to act similarly to Botox by calming contractions of the facial muscles and reducing expression wrinkles. The effect is only temporary and it does not improve the skin structure in any way.

Aureobasidium Pullulans Ferment
Est. %0.3
Function
Origin
Aureobasidium Pullulans Ferment
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Glabra (Licorice) Root ExtractAn extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Trametes Versicolor Extract
Est. %0.3
Function
Origin
Trametes Versicolor Extract
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Physalis Alkekengi Fruit Extract
Est. %0.3
Function
Origin
Physalis Alkekengi Fruit Extract
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
Camellia Sinensis Leaf Extract

An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.

Panax Ginseng Root Extract
Est. %0.3
Function
Origin
Panax Ginseng Root ExtractDerived from the roots of the Korean Ginseng, this extract contains a mixture of antioxidant and soothing ginsenosides which are proven to reduce inflammation and treat eczema. The root is a major part of Chinese traditional medicine.
Forsythia Suspensa Fruit Extract
Est. %0.3
Function
Origin
Forsythia Suspensa Fruit Extract
Dioscorea Oppositifolia (Wild Yam) Root Extract
Est. %0.3
Function
Origin
Dioscorea Oppositifolia (Wild Yam) Root Extract
Caffeine
Est. %0.3
Function
Origin
CaffeineAn antioxidant compound that is obtained from coffee and tea leaves. It increases the microcirculation of blood in the skin and is claimed to be able to reduce the appearance of orange peel skin (although the research is lacking).
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Scutellaria Baicalensis Root Extract
Est. %0.3
Function
Origin
Scutellaria Baicalensis Root ExtractA powerful antioxidant, soothing, and astringent extract derived from the roots of Baikal/Chinese skullcap. It contains various unique flavonoids that are believed to soothe irritated and inflamed skin and protect from UV-induced oxidative damage.
Illicium Verum (Anise) Fruit Extract
Est. %0.3
Function
Origin
Illicium Verum (Anise) Fruit ExtractDerived from star anise, this fragrant extract contains anethole, a volatile compound with a lovely, spicy, warm scent.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.