ISOI Blemish Care Serum Review

ISOI Blemish Care Serum
4.6
/ 10
Moisturizing
9.1 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Rich
in Antioxidants
Review

Does ISOI Blemish Care Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what ISOI Blemish Care Serum has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 4.6 out of 10.
  • Antioxidant protection.

Key Benefits of ISOI Blemish Care Serum

 
These are the key benefits you can expect from using ISOI Blemish Care Serum:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, ISOI Blemish Care Serum is quite moisturizing, with a moisturizing rating of 4.6 out of 10.

Is it more humectant or occlusive? Purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a very high humectancy of 9.1 out of 10, primarily due to the high content of Glycerin (est. ≈4.0%) and Betaine (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that ISOI Blemish Care Serum is rich (> 3%) in antioxidants, specifically Arbutin (est. ≈1.5%), Rosa Damascena Flower Oil (est. ≈1.0%), Rhodiola Rosea Root Extract (est. ≈0.3%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: ISOI Blemish Care Serum

 
CreamScan AI identified a few things to consider before adding ISOI Blemish Care Serum to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using ISOI Blemish Care Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Questionable anti-wrinkle efficacy

If one of your main reasons for choosing ISOI Blemish Care Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Centella Asiatica Extract, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Centella Asiatica Extract provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically exclude the possibility that Centella Asiatica Extract may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were accessible to the CreamScan team at the time of publication.

Therefore, this ingredient does not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of ISOI Blemish Care Serum

 
Here’s an overview of the pros and cons of ISOI Blemish Care Serum to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Humectant-rich moisturizing ideal for oily skin
  • Lightweight texture
  • A humectant moisturizing boost for any skincare routine
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage such as UV radiation and pollution

Cons: 

  • Needs occlusives to seal in humectants if used as a standalone moisturizer
  • Questionable anti-wrinkle efficacy

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Rosa Damascena Flower Water
Function:
Origin:
Glycerin
Function:
Origin:
Alcohol
Function:
Origin:
Betaine
Function:
Origin:
Arbutin
Function:
Origin:
Trehalose
Function:
Origin:
Rosa Damascena Flower Oil
Function:
Origin:
Arctostaphylos Uva-Ursi Leaf Extract
Function:
Origin:
Rhodiola Rosea Root Extract
Function:
Origin:
Hippophae Rhamnoides Fruit Extract
Function:
Origin:
Euterpe Oleracea Fruit Extract
Function:
Origin:
Vaccinium Angustifolium (Blueberry) Fruit Extract
Function:
Origin:
Phyllanthus Emblica Fruit Extract
Function:
Origin:
Vaccinium Macrocarpon (Cranberry) Fruit Extract
Function:
Origin:
Sophora Flavescens Root Extract
Function:
Origin:
Houttuynia Cordata Extract
Function:
Origin:
Xanthan Gum
Function:
Origin:
Allantoin
Function:
Origin:
Panthenol
Function:
Origin:
Adansonia Digitata Leaf Extract
Function:
Origin:
Castanea Crenata (Chestnut) Shell Extract
Function:
Origin:
Salix Alba (Willow) Bark Extract
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Butylene Glycol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Calendula Officinalis Flower Extract
Function:
Origin:
Scutellaria Baicalensis Root Extract
Function:
Origin:
Paeonia Suffruticosa Root Extract
Function:
Origin:
Glycyrrhiza Glabra (Licorice) Root Extract
Function:
Origin:
Citronellol
Function:
Origin:
Geraniol
Function:
Origin:

Ratings

All humectants
9.1
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
4.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 9.1 10
9.1
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
4.6
Ingredient Est. % Benchmark Humectancy
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 9.1 10
9.1
All humectants
9.1
4
2
1.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 0.3 -
Total
0
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 5.5 3 Rich in antioxidants
All antioxidants
5.5
Arbutin
1.5
Rosa Damascena Flower Oil
1
Rhodiola Rosea Root Extract
0.3
Euterpe Oleracea Fruit Extract
0.3
Vaccinium Angustifolium (Blueberry) Fruit Extract
0.3
Vaccinium Macrocarpon (Cranberry) Fruit Extract
0.3
Sophora Flavescens Root Extract
0.3
Houttuynia Cordata Extract
0.3
Centella Asiatica Extract
0.3
Calendula Officinalis Flower Extract
0.3
Scutellaria Baicalensis Root Extract
0.3
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All soothing 3 5 No
All soothing
3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Rosa Damascena Flower Water
Est. %6
Function
Origin
Rosa Damascena Flower WaterA fragrant water that is leftover after the steam distillation of Damask rose petals. During this process, the essential oil floats to the surface of the water and is collected. The leftover water has a fresh, rosy scent.
Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Alcohol
Est. %3
Function
Origin
AlcoholAn effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
Betaine
Est. %2
Function
Origin
BetaineAn ingredient derived from the sucrose in sugar beets. It has a negative chemical charge and a positive chemical charge on the same molecule. This allows betaine to be hygroscopic or humectant and thus provide moisturization by drawing water to the skin.
Arbutin
Est. %1.5
Function
Origin
ArbutinOne of the few potent anti-pigment compounds found naturally in bearberry or cranberry leaves. When applied to the skin, this ingredient converts into hydroquinone, with tyrosinase inhibiting effects.
Trehalose
Est. %1.3
Function
Origin
TrehaloseA sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Rosa Damascena Flower Oil
Est. %1
Function
Origin
Rosa Damascena Flower OilAlso known as Damask rose oil, it is one of the most precious and expensive essential oils in the world obtained from the petals of the Damask rose. It is used in skincare as a luxurious fragrance.
Arctostaphylos Uva-Ursi Leaf Extract
Est. %0.3
Function
Origin
Arctostaphylos Uva-Ursi Leaf Extract
Rhodiola Rosea Root Extract
Est. %0.3
Function
Origin
Rhodiola Rosea Root ExtractAn extract from the underground parts of the Golden Root (or Roseroot). It contains antioxidant and anti-pigment flavonoids, proanthocyanidins, and phenylpropanoids.
Hippophae Rhamnoides Fruit Extract
Est. %0.3
Function
Origin
Hippophae Rhamnoides Fruit Extract
Euterpe Oleracea Fruit Extract
Est. %0.3
Function
Origin
Euterpe Oleracea Fruit ExtractAn antioxidant extract obtained from the fruits of the acai palm. It has a high content of anthocyanins, responsible for the dark purple color, as well as other antioxidant phenolic compounds.
Vaccinium Angustifolium (Blueberry) Fruit Extract
Est. %0.3
Function
Origin
Vaccinium Angustifolium (Blueberry) Fruit ExtractObtained from the fruits of the lowbush blueberry, this purple-blue extract is rich in antioxidant vitamin C and anthocyanins.
Phyllanthus Emblica Fruit Extract
Est. %0.3
Function
Origin
Phyllanthus Emblica Fruit ExtractAn extract from the fruits of the Indian gooseberry, also called Amla, which is rich in acids, vitamin C, astringent tannins, and humectant moisturizing sugars.
Vaccinium Macrocarpon (Cranberry) Fruit Extract
Est. %0.3
Function
Origin
Vaccinium Macrocarpon (Cranberry) Fruit ExtractA bright red extract derived from cranberry fruits that is rich in powerful antioxidant anthocyanins, as well as astringent tannins.
Sophora Flavescens Root Extract
Est. %0.3
Function
Origin
Sophora Flavescens Root Extract
Houttuynia Cordata Extract
Est. %0.3
Function
Origin
Houttuynia Cordata ExtractAn extract from a herbaceous plant fish leaf. It contains various antioxidant and anti-inflammatory compounds. It shows interesting antimicrobial potential due to its unique phytochemical composition.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Adansonia Digitata Leaf Extract
Est. %0.3
Function
Origin
Adansonia Digitata Leaf Extract
Castanea Crenata (Chestnut) Shell Extract
Est. %0.3
Function
Origin
Castanea Crenata (Chestnut) Shell Extract
Salix Alba (Willow) Bark Extract
Est. %0.3
Function
Origin
Salix Alba (Willow) Bark ExtractA potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Centella Asiatica Extract
Est. %0.3
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Calendula Officinalis Flower Extract
Est. %0.3
Function
Origin
Calendula Officinalis Flower ExtractAn extract derived from the flowers of the pot marigold. Its yellow to bright orange flowers contain carotenoids, triterpenoids, and flavonoids. They all have fantastic anti-inflammatory activity and can help to soothe inflamed skin.
Scutellaria Baicalensis Root Extract
Est. %0.3
Function
Origin
Scutellaria Baicalensis Root ExtractA powerful antioxidant, soothing, and astringent extract derived from the roots of Baikal/Chinese skullcap. It contains various unique flavonoids that are believed to soothe irritated and inflamed skin and protect from UV-induced oxidative damage.
Paeonia Suffruticosa Root Extract
Est. %0.3
Function
Origin
Paeonia Suffruticosa Root ExtractA soothing extract obtained from a hybrid species of tree peony that contains various active compounds such as astringent tannins, terpenes, and paeonols.
Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
Glycyrrhiza Glabra (Licorice) Root ExtractAn extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Citronellol
Est. %0.3
Function
Origin
Citronellol

A fragrant compound found naturally in many essential oils (mainly lemongrass). It can have a lemon or a rose scent. People with sensitive skin should try to avoid products with citronellol, or at least do a patch test before using it.

Geraniol
Est. %0.3
Function
Origin
Geraniol

A fragrant, volatile, plant-based, liquid chemical that can be naturally found in many essential oils (specifically rose, palmarosa, citronella). It has a rose-like scent. It is a potential irritant and may cause an allergic reaction in some people.