iS Clinical Neck Perfect

iS Clinical Neck Perfect
2.6
/ 10
Moisturizing
4.9 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
3Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
$$$$

Review

Results you may expect from using iS Clinical Neck Perfect:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using iS Clinical Neck Perfect:

  • Light moisturizing. It has a moisturizing rating of 2.6 out of 10.
  • Some anti-wrinkle efficacy: iS Clinical Neck Perfect has an anti-wrinkle rating of 3.0 out of 10 so you may expect some, although limited, effect on wrinkles.
  • Antioxidant protection.

How moisturizing is it?

Lightly moisturizing: iS Clinical Neck Perfect has a moisturizing rating of 2.6 out of 10.

Is it more humectant or occlusive? Rather humectant. It has a low occlusivity of 0.3 out of 10 and a moderate humectancy of 4.9 out of 10, primarily due to Sodium Hyaluronate (est. ≈1.5%), Saccharum Officinarum (Sugarcane) Extract (est. ≈1.0%) and Glycerin (est. ≈0.3%).

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, iS Clinical Neck Perfect has a slight anti-wrinkle rating of 3.0 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Asiaticoside (est. ≈0.3%), 
derived from the plant Centella asiatica, an ingredient with moderate anti-wrinkle efficacy confirmed by one study.
Among others, iS Clinical Neck Perfect also contains some ingredients marketed as effective in reducing wrinkles, specifically Asiatic Acid, Madecassic Acid, and Camellia Sinensis Leaf Extract. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that iS Clinical Neck Perfect is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈1.5%), Vaccinium Myrtillus Fruit Extract (est. ≈1.1%), Saccharum Officinarum (Sugarcane) Extract (est. ≈1.0%), and others.

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
80
1.5
1.4
1.3
1.2
1.1
1
1
1
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
4.9
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
2.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 4.9 10
4.9
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
2.6
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient Est. % Benchmark Humectancy
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 4.9 10
4.9
All humectants
4.9
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
3 /10 0.1 0.3 3
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
3
Asiaticoside
3
Ingredient anti-wrinkle power
3 /10
when present at, %
0.1
in this formula, est. %
0.3
Asiatic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Madecassic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
3
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
1.1
1
1
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 6.4 3 Rich in antioxidants
All antioxidants
6.4
Sodium Hyaluronate
1.5
Vaccinium Myrtillus Fruit Extract
1.1
Saccharum Officinarum (Sugarcane) Extract
1
Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract
1
Asiaticoside
0.3
Citrus Aurantium Dulcis (Orange) Fruit Extract
0.3
Acer Saccharum (Sugar Maple) Extract
0.3
Glycyrrhiza Glabra (Licorice) Root Extract
0.3
Citrus Limon (Lemon) Peel Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark Rating
0.3
0.3
0.3
0.3
All soothing 1.2 5 No
All soothing
1.2
0.3
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Sodium Hyaluronate
Est. %1.5
Function
Origin
A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.
Cetearyl Alcohol
Est. %1.4
Function
Origin
A blend of cetyl alcohol and stearyl alcohol, the fatty alcohols that are derived from palm oil. It helps to create emulsions that give off a soft and silky emollient feel and also increase product thickness.
Ceteareth-20
Est. %1.3
Function
Origin
A fatty alcohol emulsifier that helps to mix oil and water together, best for oil-in-water emulsions. It is also a cleansing agent. When combined with cetearyl alcohol, ceteareth-20 forms a mix that, according to acne.org, can be comedogenic.
Hydrolyzed Quinoa
Est. %1.2
Function
Origin
Description is coming soon
Vaccinium Myrtillus Fruit Extract
Est. %1.1
Function
Origin
An extract derived from the berries of the bilberry plant, sometimes called European blueberry. It is rich in antioxidant anthocyanins and astringent tannins.
Saccharum Officinarum (Sugarcane) Extract
Est. %1
Function
Origin
An antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Hydrolyzed Rice Protein
Est. %1
Function
Origin
A protein derived from rice bran with film-forming abilities. It can help increase moisturization in skin.
Prunus Amygdalus Dulcis (Sweet Almond) Seed Extract
Est. %1
Function
Origin
Sweet almond seed extract is extracted either from whole hulled sweet almonds or from the almond press cake left over after oil pressing. It contains various organic acids, flavonoids, and tannins – which provide antioxidant effects in skincare. Read more on almonds here: Prunus Amygdalus Dulcis (Sweet Almond) Oil.
Acacia Senegal Gum
Est. %1
Function
Origin
A formula helper, also known as gum arabic, derived from the African Acacia tree. It is used in skincare formulas due to its good adhesive and film-forming properties.
Hydrolyzed Rhizobian Gum
Est. %0.3
Function
Origin
Description is coming soon
Glycerin
Est. %0.3
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
A natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Salix Alba (Willow) Bark Extract
Est. %0.3
Function
Origin
A potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Dimethicone
Est. %0.3
Function
Origin
The most common silicone in skincare. It forms a silky, smooth film on the skin’s surface and can help to prevent water loss. It also aids in wound healing and can treat and soften scars. Dimethicone is considered to be very safe for use.
Cetyl Alcohol
Est. %0.3
Function
Origin
A waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Glyceryl Stearate
Est. %0.3
Function
Origin
An emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Calcium Pantothenate
Est. %0.3
Function
Origin
A vitamin B5 derivative that reduces static buildup on the skin.
Citrus Aurantium Dulcis (Orange) Fruit Extract
Est. %0.3
Function
Origin
An extract from the fruit of the sweet orange. It contains fragrant sweet orange essential oil, high amounts of antioxidant flavonoids (mainly hesperidin), and carotenoids – which give it the orange color.
Citrus Limon (Lemon) Fruit Extract
Est. %0.3
Function
Origin
A fragrant extract from lemon peels that contains various antioxidant flavonoids, organic acids, and limonoids – which are currently under investigation as potential anti-wrinkle and anti-pigment compounds.
Acer Saccharum (Sugar Maple) Extract
Est. %0.3
Function
Origin
An antioxidant extract from sugar maple bark and sap – the same sweet sap used to make maple syrup. It has a faint vanilla smell and is used in skincare for its exfoliating properties. This is because of the small sugar crystals present in the extract.
Asiaticoside
Est. %0.3
Function
Origin

A Gotu Kola or Centella Asiatica derivative with confirmed anti-wrinkle efficacy.

Asiatic Acid
Est. %0.3
Function
Origin
A compound isolated from Gotu Kola, a promising anti-wrinkle medicinal plant from Southeast Asia. It is claimed to increase the production of collagen and help with the wound healing process.
Madecassic Acid
Est. %0.3
Function
Origin
An isolated bioactive compound from Gotu Kola. It increases collagen and hyaluronic acid production in the skin and helps to treat wounds, scars, and burns.
Salicylic Acid
Est. %0.3
Function
Origin
This effective peeling and anti-inflammatory BHA is used as an anti-acne agent and works by breaking down the junctions between dead skin cells. This results in the peeling of dead skin and the unclogging of pores.
Glycyrrhiza Glabra (Licorice) Root Extract
Est. %0.3
Function
Origin
An extract from the licorice root. It contains a well-researched anti-inflammatory compound called glycyrrhizin that can reduce inflammation. Licorice root extract is also used for its powerful antioxidant effects and ability to treat pigmentation.
Citrus Limon (Lemon) Peel Extract
Est. %0.3
Function
Origin
Derived from lemon peels, this fresh and citrusy extract contains mostly fragrant limonene, but also antioxidant flavonoids and organic acids.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Propylene Glycol
Est. %0.3
Function
Origin
A clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
1,2-Hexanediol
Est. %0.3
Function
Origin
A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Phenoxyethanol
Est. %0.3
Function
Origin
The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Chondrus Crispus
Est. %0.3
Function
Origin
An ingredient obtained from the red marine algae Irish moss. It contains a gel-forming algal polysaccharide carrageenan and is a rich source of antimicrobial iodine and sulfur. It also offers various antioxidants.
Glucose
Est. %0.3
Function
Origin
A simple sugar that is also one of two components of sucrose, or table sugar. It is used as a humectant in skincare products. Glucose is also used to flavor lip care cosmetics because of its mildly sweet taste.
PEG-150 Distearate
Est. %0.3
Function
Origin
A synthetic surfactant that thickens clear cleansers.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Polysorbate 20
Est. %0.3
Function
Origin
A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.