iS Clinical GeneXC Serum

iS Clinical GeneXC Serum
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Rich
in Antioxidants

Review

Results you may expect from using iS Clinical GeneXC Serum:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using iS Clinical GeneXC Serum:

  • Moderate moisturizing. It has a moisturizing rating of 5.0 out of 10.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: iS Clinical GeneXC Serum has a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Pentylene Glycol (est. ≈4.0%) and Trehalose (est. ≈2.0%).

Tip: Studies suggest that humectants alone do not moisturize the skin. We recommend applying a product with some occlusive ingredients after the use of this one.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, iS Clinical GeneXC Serum has a zero anti-wrinkle rating.

It contains Ascorbyl Glucoside and Camellia Sinensis Leaf Extract, two ingredients marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that iS Clinical GeneXC Serum is rich (> 3%) in antioxidants, specifically Ascorbyl Glucoside (est. ≈6.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
80
Water
6
Ascorbyl Glucoside
4
Pentylene Glycol
2
Trehalose
1.9
Glycerin
1.5
Hydrolyzed Eruca Sativa Leaf
1.3
Butylene Glycol
1
Saccharum Officinarum (Sugarcane) Extract
0.3
Citrus Limon (Lemon) Fruit Extract
0.3
Citrus Aurantium Dulcis (Orange) Fruit Extract
0.3
Pyrus Malus (Apple) Fruit Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Terminalia Ferdinandiana Fruit Extract
0.3
Acetyl Tyrosine
0.3
Proline
0.3
Hydrolyzed Vegetable Protein
0.3
Adenosine Triphosphate
0.3
Plankton Extract
0.3
Arginine Ferulate
0.3
Sucrose
0.3
Lecithin
0.3
Ethylbisiminomethylguaiacol Manganese Chloride
0.3
Phenoxyethanol
Est. %
Water
Function:
Origin:
Ascorbyl Glucoside
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Trehalose
Function:
Origin:
Glycerin
Function:
Origin:
Hydrolyzed Eruca Sativa Leaf
Function:
Origin:
Butylene Glycol
Function:
Origin:
Saccharum Officinarum (Sugarcane) Extract
Function:
Origin:
Citrus Limon (Lemon) Fruit Extract
Function:
Origin:
Citrus Aurantium Dulcis (Orange) Fruit Extract
Function:
Origin:
Pyrus Malus (Apple) Fruit Extract
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Terminalia Ferdinandiana Fruit Extract
Function:
Origin:
Acetyl Tyrosine
Function:
Origin:
Proline
Function:
Origin:
Hydrolyzed Vegetable Protein
Function:
Origin:
Adenosine Triphosphate
Function:
Origin:
Plankton Extract
Function:
Origin:
Arginine Ferulate
Function:
Origin:
Sucrose
Function:
Origin:
Lecithin
Function:
Origin:
Ethylbisiminomethylguaiacol Manganese Chloride
Function:
Origin:
Phenoxyethanol
Function:
Origin:

Ratings

All humectants
12.3
4
2
1.9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.3 10
10.0
4
2
1.9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
4
2
1.9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 12.3 10
10
All humectants
12.3
4
2
1.9
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 6 -
n/a
- 0.3 -
Total
0
Ascorbyl Glucoside
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
6
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
6
1.5
1
0.3
0.3
0.3
0.3
0.3
All antioxidants 10 3 Rich in antioxidants
All antioxidants
10
Ascorbyl Glucoside
6
Hydrolyzed Eruca Sativa Leaf
1.5
Saccharum Officinarum (Sugarcane) Extract
1
Citrus Aurantium Dulcis (Orange) Fruit Extract
0.3
Pyrus Malus (Apple) Fruit Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Terminalia Ferdinandiana Fruit Extract
0.3
Ethylbisiminomethylguaiacol Manganese Chloride
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
All soothing 0.6 5 No
All soothing
0.6
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Ascorbyl Glucoside
Est. %6
Function
Origin
Ascorbyl GlucosideA derivative of vitamin C. It is more stable and less irritating than ascorbic acid. There are unfortunately no clinical studies on ascorbyl glucoside’s anti-pigment or anti-acne efficacy alone.
Pentylene Glycol
Est. %4
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Trehalose
Est. %2
Function
Origin
TrehaloseA sweet-tasting saccharide that can be found in various yeasts and fungi and that is manufactured from starch for cosmetic purposes. It is one of the most popular sugars in skincare and is mainly used for its humectant properties.
Glycerin
Est. %1.9
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Hydrolyzed Eruca Sativa Leaf
Est. %1.5
Function
Origin
Hydrolyzed Eruca Sativa LeafDescription is coming soon
Butylene Glycol
Est. %1.3
Function
Origin
Butylene GlycolA clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Saccharum Officinarum (Sugarcane) Extract
Est. %1
Function
Origin
Saccharum Officinarum (Sugarcane) ExtractAn antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Citrus Limon (Lemon) Fruit Extract
Est. %0.3
Function
Origin
Citrus Limon (Lemon) Fruit ExtractA fragrant extract from lemon peels that contains various antioxidant flavonoids, organic acids, and limonoids – which are currently under investigation as potential anti-wrinkle and anti-pigment compounds.
Citrus Aurantium Dulcis (Orange) Fruit Extract
Est. %0.3
Function
Origin
Citrus Aurantium Dulcis (Orange) Fruit ExtractAn extract from the fruit of the sweet orange. It contains fragrant sweet orange essential oil, high amounts of antioxidant flavonoids (mainly hesperidin), and carotenoids – which give it the orange color.
Pyrus Malus (Apple) Fruit Extract
Est. %0.3
Function
Origin
Pyrus Malus (Apple) Fruit ExtractAn extract derived from apple fruit that has humectant moisturizing and antioxidant properties, as well as gentle anti-pigment effects. It contains humectant sugars, anti-pigment organic acids, and flavonoids.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
Camellia Sinensis Leaf ExtractAn antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Terminalia Ferdinandiana Fruit Extract
Est. %0.3
Function
Origin
Terminalia Ferdinandiana Fruit ExtractExtracted from the fruits of the Kakadu plum (which is the richest source of vitamin C among all plants) this ingredient acts as an excellent antioxidant. Besides this, it is also an antimicrobial agent with some humectant properties.
Acetyl Tyrosine
Est. %0.3
Function
Origin
Acetyl TyrosineAcetyl tyrosine is a derivative of the amino acid tyrosine. It is used as a tanning agent in skincare, helping pigment cells (melanosomes) to produce more dark skin pigment.
Proline
Est. %0.3
Function
Origin
ProlineThe best humectant moisturizer of all the amino acids. It is a part of the skin's Natural Moisturizing Factor and increases hydration in the top layers of the skin. It also has antioxidant activity and helps to heal damaged skin.
Hydrolyzed Vegetable Protein
Est. %0.3
Function
Origin
Hydrolyzed Vegetable ProteinA blanket term used for plant-based proteins that have been processed into smaller chunks. They add to the skincare product's film-forming and water-binding properties.
Adenosine Triphosphate
Est. %0.3
Function
Origin
Adenosine TriphosphateA cellular energy source that is thought to revitalize skin cells.
Plankton Extract
Est. %0.3
Function
Origin
Plankton ExtractAn extract from a mixture of various tiny marine animals, algae, seaweeds, and microscopic organisms jointly called plankton. One patent refers to it as a moisturizing humectant ingredient.
Arginine Ferulate
Est. %0.3
Function
Origin
Arginine FerulateDescription is coming soon
Sucrose
Est. %0.3
Function
Origin
SucroseThis ingredient is more commonly known as table sugar or saccharose and is derived from sugar beets or sugar cane. It is used as a humectant moisturizing ingredient in skincare products, as well as a sweetener.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Ethylbisiminomethylguaiacol Manganese Chloride
Est. %0.3
Function
Origin
Ethylbisiminomethylguaiacol Manganese ChlorideDescription is coming soon
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.