iS Clinical Active Peel System

iS Clinical Active Peel System
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
0.1Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
$$$$

Review

Results you may expect from using iS Clinical Active Peel System:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using iS Clinical Active Peel System:

  • Moderate moisturizing. It has a moisturizing rating of 5.0 out of 10.
  • Little anti-wrinkle effect: iS Clinical Active Peel System has an anti-wrinkle rating of 0.1 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Soothing: iS Clinical Active Peel System contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

How moisturizing is it?

Quite moisturizing: iS Clinical Active Peel System has a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Propanediol (est. ≈22.0%), Saccharum Officinarum (Sugarcane) Extract (est. ≈11.0%) and Pentylene Glycol (est. ≈4.0%).

Tip: Studies suggest that humectants alone do not moisturize the skin. We recommend applying a product with some occlusive ingredients after the use of this one.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, iS Clinical Active Peel System has a minimal anti-wrinkle rating of 0.1 out of 10. It contains one ingredient with proven anti-wrinkle efficacy: Ascorbic Acid (est. ≈0.3%),
 or Vitamin C, a popular anti-wrinkle ingredient, yet with average efficacy confirmed by only one study.
 
Among others, iS Clinical Active Peel System also contains some ingredients marketed as effective in reducing wrinkles, specifically Camellia Sinensis Leaf Extract, Imperata Cylindrica Root Extract, and Tripeptide-1. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, could deliver additional anti-wrinkle efficacy through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Antioxidant benefits

We estimate that iS Clinical Active Peel System is rich (> 3%) in antioxidants, specifically Saccharum Officinarum (Sugarcane) Extract (est. ≈11.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin soothing

Based on the ingredient list analysis, iS Clinical Active Peel System is rich (> 5%) in soothing ingredients, particularly Hamamelis Virginiana (Witch Hazel) Water (est. ≈6.0%) and Salicylic Acid (est. ≈2.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Ingredients

Est. % Ingredient Origin Functions
40
22
11
6
4
3
2
1.5
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
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Ratings

All humectants
42.1
22
11
4
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 42.1 10
10.0
22
11
4
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
22
11
4
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 42.1 10
10
All humectants
42.1
22
11
4
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2.5 /10 5 0.3 0.1
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.1
Ascorbic Acid
0.1
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
0.3
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Imperata Cylindrica Root Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.1
Ingredient Est. % Benchmark
Rich in Antioxidants
11
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 15.2 3 Rich in antioxidants
All antioxidants
15.2
Saccharum Officinarum (Sugarcane) Extract
11
Aloe Barbadensis Leaf Juice
1.5
Ascorbic Acid
0.3
Vaccinium Myrtillus Fruit Extract
0.3
Citrus Aurantium Dulcis (Orange) Fruit Extract
0.3
Camellia Sinensis Leaf Extract
0.3
Pyrus Malus (Apple) Fruit Extract
0.3
Acer Saccharum (Sugar Maple) Extract
0.3
Citrullus Lanatus (Watermelon) Fruit Extract
0.3
Lens Esculenta (Lentil) Fruit Extract
0.3
Glutathione
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
6
2
1.5
1
0.3
0.3
All soothing 10 5 Rich in soothing
All soothing
10
6
2
1.5
1
0.3
0.3
Benchmark
5

Ingredients explained

Alcohol
Est. %40
Function
Origin
An effective antimicrobial ingredient that kills bacteria, fungi, and even some viruses. It is also an excellent solvent and astringent. Alcohol helps to create lighter and less viscous products. It can, however, be dehydrating and skin-sensitizing.
Propanediol
Est. %22
Function
Origin
An excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Saccharum Officinarum (Sugarcane) Extract
Est. %11
Function
Origin
An antioxidant extract from sugarcane, the famous crop used to make sugar. It acts as a humectant and exfoliating agent – the little sugar crystals mechanically remove dead skin cells from the skin’s surface.
Hamamelis Virginiana (Witch Hazel) Water
Est. %6
Function
Origin
A fragrant, astringent essential water obtained by steeping and distilling the twigs and leaves of the witch hazel plant. It leaves the skin feeling tight and refreshed after application and helps with the healing of small cuts on the skin.
Pentylene Glycol
Est. %4
Function
Origin

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Citric Acid
Est. %3
Function
Origin
A gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Salicylic Acid
Est. %2
Function
Origin
This effective peeling and anti-inflammatory BHA is used as an anti-acne agent and works by breaking down the junctions between dead skin cells. This results in the peeling of dead skin and the unclogging of pores.
Aloe Barbadensis Leaf Juice
Est. %1.5
Function
Origin
A gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Salix Nigra (Willow) Bark Extract
Est. %1
Function
Origin
An extract obtained from black willow bark. It contains astringent tannins and salicin (which is converted to salicylic acid). Salicin has similar anti-inflammatory activity to aspirin.
Vaccinium Myrtillus Fruit Extract
Est. %0.3
Function
Origin
An extract derived from the berries of the bilberry plant, sometimes called European blueberry. It is rich in antioxidant anthocyanins and astringent tannins.
Citrus Aurantium Dulcis (Orange) Fruit Extract
Est. %0.3
Function
Origin
An extract from the fruit of the sweet orange. It contains fragrant sweet orange essential oil, high amounts of antioxidant flavonoids (mainly hesperidin), and carotenoids – which give it the orange color.
Citrus Limon (Lemon) Fruit Extract
Est. %0.3
Function
Origin
A fragrant extract from lemon peels that contains various antioxidant flavonoids, organic acids, and limonoids – which are currently under investigation as potential anti-wrinkle and anti-pigment compounds.
Camellia Sinensis Leaf Extract
Est. %0.3
Function
Origin
An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.
Pyrus Malus (Apple) Fruit Extract
Est. %0.3
Function
Origin
An extract derived from apple fruit that has humectant moisturizing and antioxidant properties, as well as gentle anti-pigment effects. It contains humectant sugars, anti-pigment organic acids, and flavonoids.
Acer Saccharum (Sugar Maple) Extract
Est. %0.3
Function
Origin
An antioxidant extract from sugar maple bark and sap – the same sweet sap used to make maple syrup. It has a faint vanilla smell and is used in skincare for its exfoliating properties. This is because of the small sugar crystals present in the extract.
Aminomethyl Propanol
Est. %0.3
Function
Origin
A synthetic ingredient that helps to adjust the pH of a product to make it less acidic.
1,2-Hexanediol
Est. %0.3
Function
Origin
A multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Caprylyl Glycol
Est. %0.3
Function
Origin
An emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Menthol
Est. %0.3
Function
Origin
A volatile compound isolated from peppermint oil. It causes a cooling sensation on the skin that can be very soothing. Menthol can also act as a topical painkiller. In more sensitive individuals, however, it may cause skin irritation or an allergy.
Fragrance
Est. %0.3
Function
Origin
Under trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Disodium EDTA
Est. %0.3
Function
Origin
A synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Water
Est. %0.3
Function
Origin
The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Scenedesmus Rubescens Extract
Est. %0.3
Function
Origin
Description is coming soon
Butylene Glycol
Est. %0.3
Function
Origin
A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.
Lentinus Edodes Mycelium Extract
Est. %0.3
Function
Origin
Description is coming soon
Glycerin
Est. %0.3
Function
Origin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Imperata Cylindrica Root Extract
Est. %0.3
Function
Origin
An extract obtained from cogongrass roots. According to the patent holder, it contains significant amounts of potassium, a humectant and anti-wrinkle compound, as well as sulfur-containing proteins.
Maltodextrin
Est. %0.3
Function
Origin
A formula helper manufactured from starch. It has a sweet flavor and is often used in rinse-off products to support their foaming structure. Maltodextrin is also used to stabilize emulsions and to absorb and bind other ingredients in the formula.
Citrullus Lanatus (Watermelon) Fruit Extract
Est. %0.3
Function
Origin
An emollient extract from red watermelon fruit. Its pulp, seeds, and rinds are a source of beneficial compounds for the skin, and it has occlusive, emollient, and antioxidant properties.
Lens Esculenta (Lentil) Fruit Extract
Est. %0.3
Function
Origin
An antioxidant extract obtained from lentil seeds that contains mainly humectant oligosaccharides. It is also a good source of amino acids and various antioxidant phenolic compounds.
Leucojum Aestivum Bulb Extract
Est. %0.3
Function
Origin
Description is coming soon
Ascorbic Acid
Est. %0.3
Function
Origin

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Glycogen
Est. %0.3
Function
Origin
Glycogen is a substance that is used in the body to store and release sugar as a form of energy storage. In skincare, however, it is utilized as a humectant moisturizing ingredient due to the thousands of glucose units in its molecule. These glucose chains attract and bind water, leaving the skin moisturized.
Sodium PCA
Est. %0.3
Function
Origin
One of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Succinic Acid
Est. %0.3
Function
Origin
Description is coming soon
Glutathione
Est. %0.3
Function
Origin
A naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Tripeptide-1
Est. %0.3
Function
Origin

A small, skin-identical peptide that boosts collagen renewal in the skin and improves other structural proteins. It may have trouble penetrating the skin in this form, so palmitic acid or biotin is usually added to it.

Colloidal Gold
Est. %0.3
Function
Origin
Description is coming soon
Sorbitol
Est. %0.3
Function
Origin
A sweet-tasting alcohol derived from glucose. Aside from its sweet taste (for which it is used as a very common sweetener), Sorbitol is also very good at retaining water and is used in skincare as a humectant.
PEG-8
Est. %0.3
Function
Origin
A synthetic liquid that serves as a humectant. It also works as a solvent because of its ability to dissolve a wide range of ingredients.
1-Methylhydantoin-2-Imide
Est. %0.3
Function
Origin
Description is coming soon
Sodium Lactate
Est. %0.3
Function
Origin
A sodium salt of lactic acid. Its main function is as a humectant but it can also serve as a pH adjuster. Additionally, sodium lactate can also be used as a chemical exfoliant due to its close chemical relation to lactic acid.
Xanthan Gum
Est. %0.3
Function
Origin
A natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Carbomer
Est. %0.3
Function
Origin
A synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Dextran
Est. %0.3
Function
Origin
A naturally derived sucrose metabolite that thickens water and bulks emulsions.

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