FFREE Body Wash II | Ingredients Explained

FFREE Body Wash II Ingredients

Hover to see details. On mobile? Tap for ingredient stories!

Full Ingredient List (INCI):

Water, Sodium Lauryl Sulfoacetate, Cocamidopropyl Betaine, Disodium Laureth Sulfosuccinate, Glycerin, Sodium Chloride, Sodium Sulfate, Aloe Barbadensis Leaf Juice, Phenoxyethanol, Tetrasodium Glutamate Diacetate

Review

Does FFREE Body Wash II Work?

FFREE Body Wash II is a type of skincare product designed to be rinsed off, peeled off, or otherwise removed from the skin. Research confirming the moisturizing, anti-wrinkle, and soothing effects of such products is very limited. Therefore, we do not provide efficacy ratings for these types of skincare products.

However, you can explore the roles of specific ingredients in the Ingredient Breakdown section below.

📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

Cleansing
Fragrance
Preservative
Flavor
Formula helpers

Other

Est. % The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more	Ingredient	Origin	Functions
80	Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients. Water The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water.	Formula helper Solvent – a liquid that dissolves other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients.
6	Sodium Lauryl Sulfoacetate A synthetic surfactant that offers excellent foaming capabilities along with mild cleansing. Sodium Lauryl Sulfoacetate A synthetic surfactant that offers excellent foaming capabilities along with mild cleansing.	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Cleansing Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Cleansing Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Formula helper Foaming – creates foam of varying densities. Formula helper Foaming – creates foam of varying densities.
4	Cocamidopropyl Betaine A mildly cleansing ingredient derived from coconut. It also produces the foam that tells us our soap is actually working to remove dirt and oils. Cocamidopropyl Betaine A mildly cleansing ingredient derived from coconut. It also produces the foam that tells us our soap is actually working to remove dirt and oils.	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Cleansing Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Cleansing Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Formula helper Antistatic – reduces electric charge buildup. Foaming – creates foam of varying densities. Viscosity controlling – changes the thickness of a product. Formula helper Antistatic – reduces electric charge buildup. Foaming – creates foam of varying densities. Viscosity controlling – changes the thickness of a product.
3	Disodium Laureth Sulfosuccinate A powerful surfactant with foaming and solubilizing abilities and potential for irritancy. Disodium Laureth Sulfosuccinate A powerful surfactant with foaming and solubilizing abilities and potential for irritancy.	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Cleansing Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Cleansing Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Formula helper Foaming – creates foam of varying densities. Hydrotrope – helps surfactants to better perform their functions. Formula helper Foaming – creates foam of varying densities. Hydrotrope – helps surfactants to better perform their functions.
2	Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective. Glycerin The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Formula helper Denaturant – turns alcohol undrinkable. Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product. Formula helper Denaturant – turns alcohol undrinkable. Solvent – a liquid that dissolves other ingredients. Viscosity controlling – changes the thickness of a product.
1.5	Sodium Chloride You’re definitely familiar with sodium chloride, even if you don’t think you are. It’s table salt! Salt works well with some cleansing ingredients (surfactants) to thicken them into gels. It also acts as a stabilizer for water-in-oil emulsions. Sodium Chloride You’re definitely familiar with sodium chloride, even if you don’t think you are. It’s table salt! Salt works well with some cleansing ingredients (surfactants) to thicken them into gels. It also acts as a stabilizer for water-in-oil emulsions.	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Flavor Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Flavor Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Formula helper Bulking – increases the volume of a product. Viscosity controlling – changes the thickness of a product. Formula helper Bulking – increases the volume of a product. Viscosity controlling – changes the thickness of a product.
1.3	Sodium Sulfate An inorganic sodium salt that provides volume and thickens emulsions. Sodium Sulfate An inorganic sodium salt that provides volume and thickens emulsions.	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Bulking – increases the volume of a product. Emulsion stabilizing – increases the stability of a formula. Viscosity controlling – changes the thickness of a product. Formula helper Bulking – increases the volume of a product. Emulsion stabilizing – increases the stability of a formula. Viscosity controlling – changes the thickness of a product.
1	Aloe Barbadensis Leaf Juice A gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties. Aloe Barbadensis Leaf Juice A gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials.	Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant) Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients.
0.3	Phenoxyethanol The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless. Phenoxyethanol The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Antimicrobial Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial Antimicrobials prevent the growth of harmful microorganisms on the skin. Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservatives prevent the growth of bacteria and fungi in a product.
0.3	Tetrasodium Glutamate Diacetate A biodegradable chelating agent that chemically captures the heavy metal ions naturally present in water and disarms their harmful effects. Tetrasodium Glutamate Diacetate A biodegradable chelating agent that chemically captures the heavy metal ions naturally present in water and disarms their harmful effects.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Chelating – deactivates harmful heavy metal ions. Formula helper Chelating – deactivates harmful heavy metal ions.

Water

Function:

Origin:

Sodium Lauryl Sulfoacetate

Function:

Origin:

Cocamidopropyl Betaine

Function:

Origin:

Disodium Laureth Sulfosuccinate

Function:

Origin:

Glycerin

Function:

Origin:

1.5

Sodium Chloride

Function:

Origin:

1.3

Sodium Sulfate

Function:

Origin:

Aloe Barbadensis Leaf Juice

Function:

Origin:

0.3

Phenoxyethanol

Function:

Origin:

0.3

Tetrasodium Glutamate Diacetate

Function:

Origin:

Ingredients explained

Water
Est. %	80
Function	Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water.

The most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.

Sodium Lauryl Sulfoacetate
Est. %	6
Function	Cleansing, Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Cleansing, Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Foaming Foaming – creates foam of varying densities. Foaming Foaming – creates foam of varying densities.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A synthetic surfactant that offers excellent foaming capabilities along with mild cleansing.

Cocamidopropyl Betaine
Est. %	4
Function	Cleansing, Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Cleansing, Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Antistatic, Antistatic – reduces electric charge buildup. Antistatic, Antistatic – reduces electric charge buildup. Foaming, Foaming – creates foam of varying densities. Foaming, Foaming – creates foam of varying densities. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A mildly cleansing ingredient derived from coconut. It also produces the foam that tells us our soap is actually working to remove dirt and oils.

Disodium Laureth Sulfosuccinate
Est. %	3
Function	Cleansing, Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Cleansing, Cleansing ingredients, also known as surfactants, clear dirt and buildup from the skin. Foaming, Foaming – creates foam of varying densities. Foaming, Foaming – creates foam of varying densities. Hydrotrope Hydrotrope – helps surfactants to better perform their functions. Hydrotrope Hydrotrope – helps surfactants to better perform their functions.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A powerful surfactant with foaming and solubilizing abilities and potential for irritancy.

Glycerin
Est. %	2
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Denaturant, Denaturant – turns alcohol undrinkable. Denaturant, Denaturant – turns alcohol undrinkable. Solvent, Solvent – a liquid that dissolves other ingredients. Solvent, Solvent – a liquid that dissolves other ingredients. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Sodium Chloride
Est. %	1.5
Function	Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Fragrance, Fragrance ingredients add scent to a product or hide ('mask') the undesired aroma of other ingredients. Flavor, Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Flavor, Flavor ingredients bring sweetness to a product or are used to recreate various tastes. Bulking, Bulking – increases the volume of a product. Bulking, Bulking – increases the volume of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Naturally occurring, These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring, These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

You’re definitely familiar with sodium chloride, even if you don’t think you are. It’s table salt! Salt works well with some cleansing ingredients (surfactants) to thicken them into gels. It also acts as a stabilizer for water-in-oil emulsions.

Sodium Sulfate
Est. %	1.3
Function	Bulking, Bulking – increases the volume of a product. Bulking, Bulking – increases the volume of a product. Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Naturally occurring, These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Naturally occurring, These are ingredients initially present in nature, such as elements (Zinc, Gold, or Silver), minerals, or water. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

An inorganic sodium salt that provides volume and thickens emulsions.

Aloe Barbadensis Leaf Juice
Est. %	1
Function	Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Moisturizing (Humectant), Humectants are moisturizing ingredients that draw moisture to the skin, either from deeper layers or from the environment (when it's humid). Antioxidant, Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Antioxidant, Antioxidants reduce the oxidative stress caused by free radicals and prevent accelerated skin aging. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Soothing, Soothing ingredients reduce the signs of sensitivity in irritated and inflamed skin. This includes anti-inflammatory ingredients, anti-itch agents, and topical analgesics. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients.
Origin	Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials.

A gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.

Phenoxyethanol
Est. %	0.3
Function	Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservatives prevent the growth of bacteria and fungi in a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.

Tetrasodium Glutamate Diacetate
Est. %	0.3
Function	Chelating Chelating – deactivates harmful heavy metal ions. Chelating Chelating – deactivates harmful heavy metal ions.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.