DRMTLGY Vitamin C E + F Review

DRMTLGY Vitamin C E + F
3.6
/ 10
Moisturizing
6.7 Humectancy icon Humectancy
0.6 Occlusivity icon Occlusivity
2.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Ingredients

DRMTLGY Vitamin C E + F Ingredients

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Full Ingredient List (INCI):

Water, Ascorbic Acid, Ethoxydiglycol, PEG-40 Hydrogenated Castor Oil, PPG-26-Buteth-26, Glycerin, Tocopherol, Ferulic Acid, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Sodium Lauroyl Lactylate, Butylene Glycol, Carbomer, Polysorbate 20, Xanthan Gum, Sodium Hyaluronate, Sodium Metabisulfite, Acetyl Octapeptide-3, Phenoxyethanol, Triethanolamine, Panthenol
Review

Does DRMTLGY Vitamin C E + F Work?

 
According to CreamScan's analysis of the ingredient list, here’s what DRMTLGY Vitamin C E + F has to offer:
 
✅ Light moisturizing. It has a moisturizing rating of 3.6 out of 10.
✅ Modest anti-wrinkle efficacy: DRMTLGY Vitamin C E + F has an anti-wrinkle rating of 2.5 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection

  

Key Benefits of DRMTLGY Vitamin C E + F

 
These are the key benefits you can expect from using DRMTLGY Vitamin C E + F:
 

🔵 Lightweight Moisturizer Well-Suited for Oily Skin

According to CreamScan analysis, DRMTLGY Vitamin C E + F is lightly moisturizing, with a moisturizing rating of 3.6 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.6 out of 10 and a high humectancy of 6.7 out of 10, primarily due to the high content of Ethoxydiglycol (est. ≈4.0%).

This humectant-rich product, when used alone as a moisturizer, is well-suited for oily skin, providing moderate hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It can also be a good option for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Enhancement for Any Skincare Routine

But it’s not limited to oily skin - such a humectant enhancement will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, DRMTLGY Vitamin C E + F has a modest level of anti-wrinkle efficacy, rated 2.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Ascorbic Acid (est. ≈6.0%),
 or Vitamin C, a popular ingredient, yet with moderate anti-wrinkle efficacy, as confirmed by a single clinical study involving 20 participants (Humbert et al.). This study showed that a cream with a relatively high concentration of 5% ascorbic acid reduced the average wrinkle depth by 7% after 6 months of use, compared to a vehicle (the same formulation without ascorbic acid).
 
Among others, DRMTLGY Vitamin C E + F contains some ingredients often marketed as effective in reducing wrinkles, specifically Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, and Acetyl Octapeptide-3. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that DRMTLGY Vitamin C E + F is rich (> 3%) in antioxidants, specifically Ascorbic Acid (est. ≈6.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of DRMTLGY Vitamin C E + F

 
Here’s an overview of the pros and cons of DRMTLGY Vitamin C E + F to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing well-suited for oily skin
✅ As part of a routine: A humectant moisturizing enhancement, beneficial for any skin type
✅ Lightweight texture
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: DRMTLGY Vitamin C E + F

 
Based on the ingredient list analysis, CreamScan AI suggests that DRMTLGY Vitamin C E + F
, when used alone, delivers lightweight, humectant-rich moisturizing that is well-suited for oily skin. As part of a moisturizing routine, it provides a humectant enhancement, beneficial for all skin types.
 
DRMTLGY Vitamin C E + F contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, DRMTLGY Vitamin C E + F helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Ascorbic Acid
Function:
Origin:
Ethoxydiglycol
Function:
Origin:
PEG-40 Hydrogenated Castor Oil
Function:
Origin:
PPG-26-Buteth-26
Function:
Origin:
Glycerin
Function:
Origin:
Tocopherol
Function:
Origin:
Ferulic Acid
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Ceramide EOP
Function:
Origin:
Ceramide NP
Function:
Origin:
Palmitoyl Tripeptide-5
Function:
Origin:
Ceramide AP
Function:
Origin:
Phytosphingosine
Function:
Origin:
Cholesterol
Function:
Origin:
Sodium Lauroyl Lactylate
Function:
Origin:
Butylene Glycol
Function:
Origin:
Carbomer
Function:
Origin:
Polysorbate 20
Function:
Origin:
Xanthan Gum
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Sodium Metabisulfite
Function:
Origin:
Acetyl Octapeptide-3
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Triethanolamine
Function:
Origin:
Panthenol
Function:
Origin:

Ratings

All humectants
6.7
4
1.5
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
1.3
1.3
Benchmark
20
Moisturizing rating
3.6
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 6.7 10
6.7
4
1.5
0.3
0.3
0.3
0.3
Occlusivity All occlusives 1.3 20
0.6
1.3
Moisturizing rating
3.6
Ingredient Est. % Benchmark Humectancy
4
1.5
0.3
0.3
0.3
0.3
All humectants 6.7 10
6.7
All humectants
6.7
4
1.5
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
1.3
All occlusives 1.3 20
0.6
All occlusives
1.3
1.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2.5 /10 5 6 2.5
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
2.5
Ascorbic Acid
2.5
Ingredient anti-wrinkle power
2.5 /10
when present at, %
5
in this formula, est. %
6
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-5
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Acetyl Octapeptide-3
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.5
Ingredient Est. % Benchmark
Rich in Antioxidants
6
1.3
1
0.3
0.3
All antioxidants 8.9 3 Rich in antioxidants
All antioxidants
8.9
Ascorbic Acid
6
Tocopherol
1.3
Ferulic Acid
1
Sodium Hyaluronate
0.3
Sodium Metabisulfite
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
All soothing 0.6 5 No
All soothing
0.6
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Ascorbic Acid
Est. %6
Function
Origin
Ascorbic Acid

Also known as vitamin C, this multi-benefit ingredient has proven anti-wrinkle, antioxidant, and anti-pigmentation efficacy. It degrades easily when exposed to air and light, so it requires proper packaging to maintain its stability.

Ethoxydiglycol
Est. %4
Function
Origin
EthoxydiglycolA type of alcohol with humectant moisturizing properties. It also acts as a solvent, since it mixes well with a variety of other compounds, including water and even some oils.
PEG-40 Hydrogenated Castor Oil
Est. %3
Function
Origin
PEG-40 Hydrogenated Castor OilA castor oil-derived ingredient often used to incorporate small amounts of oil (such as a fragrance) into a water-based product. PEG-4 HCO is a gold-standard solubilizer and can be used in low amounts due to its ability to solubilize things so well.
PPG-26-Buteth-26
Est. %2
Function
Origin
PPG-26-Buteth-26A water-loving surfactant, which means it can act as an emulsifier, solubilizer, and cleansing agent. As an emulsifier, it helps to create oil-in-water emulsions.
Glycerin
Est. %1.5
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Tocopherol
Est. %1.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Ferulic Acid
Est. %1
Function
Origin
Ferulic AcidA plant-based phenolic acid with powerful and scientifically proven antioxidant properties. It enhances the effects of vitamins C and E, as well as the UV protective effects of sunscreens.
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Ceramide EOP
Est. %0.3
Function
Origin
Ceramide EOP

Formerly called Ceramide 1, this ingredient is a skin-identical wax-like lipid with an ultra-long fatty acid chain. It restores and stabilizes the skin’s lipid matrix and helps to treat dry and flaky skin, especially when combined with other ceramides.

Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Palmitoyl Tripeptide-5
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-5

A small synthetic peptide that signals the skin to produce more collagen. It has been clinically tested and proven to reduce skin roughness and the appearance of wrinkles.

Ceramide AP
Est. %0.3
Function
Origin
Ceramide APPreviously called Ceramide 6 II, Ceramide AP is one of the most common ceramides in the skin. Research has shown that dry, flaky skin has significantly less Ceramide AP. Its application helps to treat dry skin by restoring balance in the skin lipids.
Phytosphingosine
Est. %0.3
Function
Origin
PhytosphingosineA key component of ceramides NP, AP, and EOP. It has barrier repair properties and stimulates the production of the skin’s Natural Moisturizing Factor. Phytosphingosine has strong antimicrobial and anti-inflammatory activity, which can be used to treat acne.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Sodium Lauroyl Lactylate
Est. %0.3
Function
Origin
Sodium Lauroyl LactylateA multifunctional ingredient that produces foamy cleansers and allows oil and water to mix.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Sodium Metabisulfite
Est. %0.3
Function
Origin
Sodium MetabisulfiteA preservative that is especially effective at preventing fungus and mold growth. It is normally combined with a strong bactericidal preservative in order to achieve broad-spectrum protection. Sodium metabisulfite is also used as an antioxidant.
Acetyl Octapeptide-3
Est. %0.3
Function
Origin
Acetyl Octapeptide-3

A synthetically made peptide with an effect similar to Botox - it relaxes the facial muscles and temporarily reduces the appearance of mimic wrinkles.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Triethanolamine
Est. %0.3
Function
Origin
TriethanolamineA clear, colorless, and highly viscous liquid, this ingredient is an excellent pH adjuster. When it is necessary to neutralize an acidic solution or to generally increase the pH of a product, triethanolamine is a common choice.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.