DRMTLGY Needle-Less Serum

DRMTLGY Needle-Less Serum
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
0.4Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants

Review

Does DRMTLGY Needle-Less Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using DRMTLGY Needle-Less Serum:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Little anti-wrinkle effect: DRMTLGY Needle-Less Serum has an anti-wrinkle rating of 0.4 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.
  • Antioxidant protection.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, DRMTLGY Needle-Less Serum is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%), Sodium Hyaluronate (est. ≈2.5%) and Pisum Sativum (Pea) Extract (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Little anti-wrinkle efficacy

According to CreamScan analysis, DRMTLGY Needle-Less Serum has a minimal anti-wrinkle rating of 0.4 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈0.3%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, DRMTLGY Needle-Less Serum also contains some ingredients often marketed as effective in reducing wrinkles, specifically Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, and Copper Lysinate/Prolinate. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in skin-protecting antioxidants

We estimate that DRMTLGY Needle-Less Serum is rich (> 3%) in antioxidants, specifically Sodium Hyaluronate (est. ≈2.5%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
2.5
2
1.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Sodium Chondroitin Sulfate
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Pisum Sativum (Pea) Extract
Function:
Origin:
Bambusa Vulgaris Leaf/Stem Extract
Function:
Origin:
Palmitoyl Tripeptide-1
Function:
Origin:
Palmitoyl Tetrapeptide-7
Function:
Origin:
Ceramide EOP
Function:
Origin:
Glucosamine HCl
Function:
Origin:
Glycosaminoglycans
Function:
Origin:
Ceramide NP
Function:
Origin:
Palmitoyl Tripeptide-5
Function:
Origin:
Ceramide AP
Function:
Origin:
Phytosphingosine
Function:
Origin:
Cholesterol
Function:
Origin:
Niacinamide
Function:
Origin:
Sodium Lauroyl Lactylate
Function:
Origin:
Methylglucoside Phosphate
Function:
Origin:
Copper Lysinate/Prolinate
Function:
Origin:
Panthenol
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Polysorbate 20
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Disodium EDTA
Function:
Origin:
Butylene Glycol
Function:
Origin:
Carbomer
Function:
Origin:
Xanthan Gum
Function:
Origin:

Ratings

All humectants
13.2
6
2.5
2
1.5
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 13.2 10
10.0
6
2.5
2
1.5
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
2.5
2
1.5
0.3
0.3
0.3
0.3
All humectants 13.2 10
10
All humectants
13.2
6
2.5
2
1.5
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 0.3 0.4
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0.4
Niacinamide
0.4
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
0.3
Palmitoyl Tripeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tetrapeptide-7
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Palmitoyl Tripeptide-5
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Copper Lysinate/Prolinate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0.4
Ingredient Est. % Benchmark
Rich in Antioxidants
2.5
0.3
0.3
All antioxidants 3.1 3 Rich in antioxidants
All antioxidants
3.1
Sodium Hyaluronate
2.5
Niacinamide
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
0.3
All soothing 0.9 5 No
All soothing
0.9
0.3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Sodium Chondroitin Sulfate
Est. %4
Function
Origin
Sodium Chondroitin SulfateA compound related to hyaluronic acid. It can create a film on the skin that binds and retains a lot of water, thereby keeping the skin hydrated. It also has additional antioxidant and soothing properties.
Sodium Hyaluronate
Est. %2.5
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Pisum Sativum (Pea) Extract
Est. %2
Function
Origin
Pisum Sativum (Pea) ExtractAn extract derived from peas that contains many proteins with humectant moisturizing properties. Patents have claimed that it is able to stimulate cell renewal and increase melanin production.
Bambusa Vulgaris Leaf/Stem Extract
Est. %1.5
Function
Origin
Bambusa Vulgaris Leaf/Stem Extract
Palmitoyl Tripeptide-1
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-1

A small peptide consisting of three amino acids with anti-wrinkle effects. Together with Palmitoyl Tetrapeptide-7, it is a part of the popular anti-wrinkle complex called Matrixyl™ 3000.

Palmitoyl Tetrapeptide-7
Est. %0.3
Function
Origin
Palmitoyl Tetrapeptide-7

A synthetic peptide that mimics the activity of immunoglobulin G and signals to the skin to stop the inflammation. It has been shown in studies to reduce wrinkles and enhance collagen content.

Ceramide EOP
Est. %0.3
Function
Origin
Ceramide EOP

Formerly called Ceramide 1, this ingredient is a skin-identical wax-like lipid with an ultra-long fatty acid chain. It restores and stabilizes the skin’s lipid matrix and helps to treat dry and flaky skin, especially when combined with other ceramides.

Glucosamine HCl
Est. %0.3
Function
Origin
Glucosamine HClA naturally occurring compound that reduces static and lowers the pH of skincare products.
Glycosaminoglycans
Est. %0.3
Function
Origin
GlycosaminoglycansA blanket term used for the structural polysaccharides of the skin, such as hyaluronic acid and chondroitin. They add to a skincare product's film-forming and water-binding properties.
Ceramide NP
Est. %0.3
Function
Origin
Ceramide NPAlso known as ceramide 3, it is the most common ceramide in our skin. It helps to restore the skin’s lipid barrier and alleviate the symptoms of dry and cracked skin. Research has shown that skin suffering from conditions such as AD lacks ceramides.
Palmitoyl Tripeptide-5
Est. %0.3
Function
Origin
Palmitoyl Tripeptide-5

A small synthetic peptide that signals the skin to produce more collagen. It has been clinically tested and proven to reduce skin roughness and the appearance of wrinkles.

Ceramide AP
Est. %0.3
Function
Origin
Ceramide APPreviously called Ceramide 6 II, Ceramide AP is one of the most common ceramides in the skin. Research has shown that dry, flaky skin has significantly less Ceramide AP. Its application helps to treat dry skin by restoring balance in the skin lipids.
Phytosphingosine
Est. %0.3
Function
Origin
PhytosphingosineA key component of ceramides NP, AP, and EOP. It has barrier repair properties and stimulates the production of the skin’s Natural Moisturizing Factor. Phytosphingosine has strong antimicrobial and anti-inflammatory activity, which can be used to treat acne.
Cholesterol
Est. %0.3
Function
Origin
CholesterolAn emollient and important barrier repairing lipid, effective when combined with fatty acids and ceramides. Around 25% of the skin’s lipid layer is made up of cholesterol and it is found in the membrane of every single cell in our body.
Niacinamide
Est. %0.3
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Sodium Lauroyl Lactylate
Est. %0.3
Function
Origin
Sodium Lauroyl LactylateA multifunctional ingredient that produces foamy cleansers and allows oil and water to mix.
Methylglucoside Phosphate
Est. %0.3
Function
Origin
Methylglucoside PhosphateA derivative of glucose. It is allegedly an activated form of glucose that may be able to serve as an energy source to the skin, although this claim has not been supported by any research.
Copper Lysinate/Prolinate
Est. %0.3
Function
Origin
Copper Lysinate/ProlinateA complex of copper and two amino acids. It may stimulate the production of collagen in the skin because of the supply of copper, thus resulting in anti-wrinkle effects. This, however, has not been confirmed by studies.
Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.