Cetaphil Healthy Renew Purified Peptides Face Serum

Cetaphil Healthy Renew Purified Peptides Face Serum
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
2.2Anti-wrinkle icon/ 10
Anti-wrinkle

Review

Does Cetaphil Healthy Renew Purified Peptides Face Serum work?

Based on the ingredient list analysis by CreamScan AI, these are the key benefits you can expect from using Cetaphil Healthy Renew Purified Peptides Face Serum:

  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.1 out of 10.
  • Some anti-wrinkle efficacy: Cetaphil Healthy Renew Purified Peptides Face Serum has an anti-wrinkle rating of 2.2 out of 10 so you may expect some, although limited, effect on wrinkles.

Lightweight moisturizer ideal for oily skin and a humectant boost for any skincare routine

According to CreamScan analysis, Cetaphil Healthy Renew Purified Peptides Face Serum is quite moisturizing, with a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Butylene Glycol (est. ≈6.0%), Glycerin (est. ≈4.0%) and Panthenol (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients. It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

Such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Some anti-wrinkle efficacy

According to CreamScan analysis, Cetaphil Healthy Renew Purified Peptides Face Serum has a slight anti-wrinkle rating of 2.2 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈1.5%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Cetaphil Healthy Renew Purified Peptides Face Serum also contains Adenosine, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Adenosine provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Butylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Panthenol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Niacinamide
Function:
Origin:
Cetyl Ethylhexanoate
Function:
Origin:
Hydrogenated Polydecene
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Tromethamine
Function:
Origin:
Oryza Sativa (Rice) Lees Extract
Function:
Origin:
Leontopodium Alpinum Extract
Function:
Origin:
Calcium Alginate
Function:
Origin:
Propanediol
Function:
Origin:
Hydrolyzed Soy Flour
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Agar
Function:
Origin:
Adenosine
Function:
Origin:
Trisodium Ethylenediamine Disuccinate
Function:
Origin:
Synthetic Fluorphlogopite
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Iron Oxides
Function:
Origin:
Citric Acid
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Buddleja Davidii Extract
Function:
Origin:
Thymus Vulgaris (Thyme) Extract
Function:
Origin:
Tocopherol
Function:
Origin:

Ratings

All humectants
15.4
6
4
3
1.5
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 15.4 10
10.0
6
4
3
1.5
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
6
4
3
1.5
0.3
0.3
0.3
All humectants 15.4 10
10
All humectants
15.4
6
4
3
1.5
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 1.5 2.2
n/a
- 0.3 -
Total
2.2
Niacinamide
2.2
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
1.5
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.2
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
0.3
0.3
0.3
0.3
All antioxidants 2.7 3 No
All antioxidants
2.7
Niacinamide
1.5
Leontopodium Alpinum Extract
0.3
Buddleja Davidii Extract
0.3
Thymus Vulgaris (Thyme) Extract
0.3
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
1.5
0.3
All soothing 4.8 5 No
All soothing
4.8
3
1.5
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Butylene Glycol
Est. %6
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Panthenol
Est. %3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
1,2-Hexanediol
Est. %2
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Niacinamide
Est. %1.5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Cetyl Ethylhexanoate
Est. %1.3
Function
Origin
Cetyl EthylhexanoateA clear, pale yellow liquid, that functions as an emollient and a solvent, meaning that it is useful for dissolving oil-soluble ingredients.
Hydrogenated Polydecene
Est. %1
Function
Origin
Hydrogenated PolydeceneA clear, colorless, highly viscous liquid that commonly serves as an emollient. This rich emollient is on the heavier side but provides a smooth sensorial profile upon application.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Tromethamine
Est. %0.3
Function
Origin
TromethamineAn ingredient based on amino acids that is commonly used as a pH adjuster. It has a high pH, which means that it is basic (alkaline), so adding tromethamine to a skincare product will increase its overall pH level.
Oryza Sativa (Rice) Lees Extract
Est. %0.3
Function
Origin
Oryza Sativa (Rice) Lees Extract
Leontopodium Alpinum Extract
Est. %0.3
Function
Origin
Leontopodium Alpinum ExtractAn extract from a beautiful alpine plant called Edelweiss. It contains a rare compound called leontopodic acid with antioxidant, antibacterial, and anti-inflammatory properties.
Calcium Alginate
Est. %0.3
Function
Origin
Calcium Alginate
Propanediol
Est. %0.3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Hydrolyzed Soy Flour
Est. %0.3
Function
Origin
Hydrolyzed Soy Flour
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Agar
Est. %0.3
Function
Origin
AgarA multifunctional jelly derived from red algae that can thicken water-based products.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Trisodium Ethylenediamine Disuccinate
Est. %0.3
Function
Origin
Trisodium Ethylenediamine DisuccinateA chelating agent that disables harmful heavy metal ions present in skincare.
Synthetic Fluorphlogopite
Est. %0.3
Function
Origin
Synthetic FluorphlogopiteAlso known as synthetic mica, this ingredient’s best property is its ability to form thin, sheet-like crystals. This gives products (mostly makeup) great slip.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Iron Oxides
Est. %0.3
Function
Origin
Iron OxidesMineral pigments used to provide color in skincare products. These naturally occurring pigments are available in yellow, red, brown, and black powders.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Buddleja Davidii Extract
Est. %0.3
Function
Origin
Buddleja Davidii ExtractAn extract of summer lilac with antioxidant and anti-inflammatory compounds such as iridoids, various terpenes, flavonoids, and phenolic acids. More research is needed in order to evaluate its functions.
Thymus Vulgaris (Thyme) Extract
Est. %0.3
Function
Origin
Thymus Vulgaris (Thyme) ExtractDerived from thyme, this antioxidant, antiseptic and fragrant extract consists mainly of thyme essential oil (with its spicy herbal scent), flavonoids, terpenes, and organic acids.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.