By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum Review

By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum
5.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.3 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.2 out of 10.
✅ Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum is effective in minimizing wrinkles.
✅ Soothing: By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum

 
These are the key benefits you can expect from using By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum is quite moisturizing, with a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.3 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Niacinamide (est. ≈10.0%), Aloe Barbadensis Leaf Juice (est. ≈4.0%) and Glycerin (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈10.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum also contains Centella Asiatica Extract, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Centella Asiatica Extract provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Centella Asiatica Extract may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈10.0%), Aloe Barbadensis Leaf Juice (est. ≈4.0%) and Sodium Hyaluronate (est. ≈2.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈10.0%) and Aloe Barbadensis Leaf Juice (est. ≈4.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Pros & Cons of By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum

 
Here’s an overview of the pros and cons of By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers signficant anti-wrinkle efficacy thanks to Niacinamide
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients like Niacinamide and Aloe Barbadensis Leaf Juice
 

⭕ Cons: 

✅ We couldn't find any
   

Summary: By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum
 is specifically effective in treating wrinkles, containing ingredients with solid, robust evidence of anti-wrinkle efficacy.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, By Nature Cica + 10% Niacinamide + Willow Bark Calming Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
75
10
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Niacinamide
Function:
Origin:
Aloe Barbadensis Leaf Juice
Function:
Origin:
Glycerin
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Centella Asiatica Extract
Function:
Origin:
Salix Alba (Willow) Bark Extract
Function:
Origin:
Pentylene Glycol
Function:
Origin:
Xanthan Gum
Function:
Origin:
Sodium Acrylates Copolymer
Function:
Origin:
Helianthus Annuus (Sunflower) Seed Oil
Function:
Origin:
Tocopherol
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Lecithin
Function:
Origin:
Fragrance
Function:
Origin:
Sodium Citrate
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Geraniol
Function:
Origin:
Limonene
Function:
Origin:

Ratings

All humectants
20.6
10
4
3
2
1
0.3
0.3
Benchmark
10
All occlusives
0.6
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 20.6 10
10.0
10
4
3
2
1
0.3
0.3
Occlusivity All occlusives 0.6 20
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Humectancy
10
4
3
2
1
0.3
0.3
All humectants 20.6 10
10
All humectants
20.6
10
4
3
2
1
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
All occlusives 0.6 20
0.3
All occlusives
0.6
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 10 6
n/a
- 1.5 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
10
Centella Asiatica Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
10
4
2
1.5
0.3
All antioxidants 17.8 3 Rich in antioxidants
All antioxidants
17.8
Niacinamide
10
Aloe Barbadensis Leaf Juice
4
Sodium Hyaluronate
2
Centella Asiatica Extract
1.5
Tocopherol
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
10
4
1.5
1.3
All soothing 16.8 5 Rich in soothing
All soothing
16.8
10
4
1.5
1.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Niacinamide
Est. %10
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Aloe Barbadensis Leaf Juice
Est. %4
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Glycerin
Est. %3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Sodium Hyaluronate
Est. %2
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Centella Asiatica Extract
Est. %1.5
Function
Origin
Centella Asiatica ExtractAn extract from the leaves of the Gotu kola. It is used in skincare for its antioxidant, wound healing, anti-inflammatory, and anti-aging properties. It increases the production of collagen and hyaluronic acid in the skin.
Salix Alba (Willow) Bark Extract
Est. %1.3
Function
Origin
Salix Alba (Willow) Bark ExtractA potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Pentylene Glycol
Est. %1
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

Xanthan Gum
Est. %0.3
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Sodium Acrylates Copolymer
Est. %0.3
Function
Origin
Sodium Acrylates CopolymerA synthetic polymer that can come in various forms and is often used to create light gel-like textures. Some versions can also create a light film on the skin.
Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
Helianthus Annuus (Sunflower) Seed OilA fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Tocopherol
Est. %0.3
Function
Origin
Tocopherol

Simply another name for vitamin E. Tocopherol is a fantastic ingredient and especially beneficial for dry and inflamed skin. It has occlusive moisturizing, emollient, antioxidant, and photoprotective properties.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.
Sodium Citrate
Est. %0.3
Function
Origin
Sodium CitrateA salt of citric acid that has a salty and tart flavor and is used as a fragrance. It is mildly basic, meaning that its addition to a skincare product can adjust the pH upward.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Geraniol
Est. %0.3
Function
Origin
Geraniol

A fragrant, volatile, plant-based, liquid chemical that can be naturally found in many essential oils (specifically rose, palmarosa, citronella). It has a rose-like scent. It is a potential irritant and may cause an allergic reaction in some people.

Limonene
Est. %0.3
Function
Origin
Limonene

One of the most used fragrances in skincare products. It is produced from the peels of citrus fruits and has a fresh, pleasant, citrusy smell. People who are sensitive to citrus should try to avoid it, or at least do a patch test before using it.