Biologique Recherche ISO-Placenta Regenerating Serum for Face Review

Biologique Recherche ISO-Placenta Regenerating Serum for Face
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
Review

Does Biologique Recherche ISO-Placenta Regenerating Serum for Face Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Biologique Recherche ISO-Placenta Regenerating Serum for Face has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.

Key Benefits of Biologique Recherche ISO-Placenta Regenerating Serum for Face

 
These are the key benefits you can expect from using Biologique Recherche ISO-Placenta Regenerating Serum for Face:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Biologique Recherche ISO-Placenta Regenerating Serum for Face is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Propanediol (est. ≈6.0%) and Methylpropanediol (est. ≈4.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Biologique Recherche ISO-Placenta Regenerating Serum for Face

 
CreamScan AI identified a few things to consider before adding Biologique Recherche ISO-Placenta Regenerating Serum for Face to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Biologique Recherche ISO-Placenta Regenerating Serum for Face as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Biologique Recherche ISO-Placenta Regenerating Serum for Face is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains some ingredients often marketed as effective in reducing wrinkles, specifically Camellia Sinensis Leaf Extract, Oligopeptide-1, and Folic Acid. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. 

While this does not categorically exclude the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were accessible to the CreamScan team at the time of publication.

Therefore, these ingredients do not generate the anti-wrinkle rating.

Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Biologique Recherche ISO-Placenta Regenerating Serum for Face

 
Here’s an overview of the pros and cons of Biologique Recherche ISO-Placenta Regenerating Serum for Face to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Humectant-rich moisturizing ideal for oily skin
  • Lightweight texture
  • A humectant moisturizing boost for any skincare routine

Cons: 

  • Needs occlusives to seal in humectants if used as a standalone moisturizer
  • Questionable anti-wrinkle efficacy

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Propanediol
Function:
Origin:
Methylpropanediol
Function:
Origin:
Alcohol Denat.
Function:
Origin:
Ceratonia Siliqua (Carob) Seed Extract
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Onopordum Acanthium Flower/Leaf/Stem Extract
Function:
Origin:
Bacillus/Soybean Ferment Extract
Function:
Origin:
Hexapeptide-11
Function:
Origin:
Oligopeptide-1
Function:
Origin:
Oligopeptide-2
Function:
Origin:
Oligopeptide-3
Function:
Origin:
Acetyl Glutamine
Function:
Origin:
Folic Acid
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Citric Acid
Function:
Origin:
Lecithin
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Butylene Glycol
Function:
Origin:
Triethanolamine
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Sodium Benzoate
Function:
Origin:

Ratings

All humectants
12.7
6
4
1.5
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 12.7 10
10.0
6
4
1.5
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
1.5
0.3
0.3
0.3
0.3
All humectants 12.7 10
10
All humectants
12.7
6
4
1.5
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 1.5 -
n/a
- 0.3 -
n/a
- 0.3 -
Total
0
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Oligopeptide-1
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Folic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
1.5
0.3
All antioxidants 1.8 3 No
All antioxidants
1.8
Camellia Sinensis Leaf Extract
1.5
Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
1.5
All soothing 1.5 5 No
All soothing
1.5
1.5
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Propanediol
Est. %6
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Methylpropanediol
Est. %4
Function
Origin
MethylpropanediolMethylpropanediol is a unique glycol that contains two primary hydroxyl groups. That makes methylpropanediol a powerful humectant and an excellent solvent.
Alcohol Denat.
Est. %3
Function
Origin
Alcohol Denat.

Denatured alcohol is ethanol that contains additives that make it unsafe to consume. It is mainly used as a solvent and an antimicrobial agent. A major drawback to alcohol denat. is that it dries out the skin.

Ceratonia Siliqua (Carob) Seed Extract
Est. %2
Function
Origin
Ceratonia Siliqua (Carob) Seed Extract
Camellia Sinensis Leaf Extract
Est. %1.5
Function
Origin
Camellia Sinensis Leaf Extract

An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.

Onopordum Acanthium Flower/Leaf/Stem Extract
Est. %1.3
Function
Origin
Onopordum Acanthium Flower/Leaf/Stem Extract
Bacillus/Soybean Ferment Extract
Est. %1
Function
Origin
Bacillus/Soybean Ferment Extract
Hexapeptide-11
Est. %0.3
Function
Origin
Hexapeptide-11

Description is coming soon

Oligopeptide-1
Est. %0.3
Function
Origin
Oligopeptide-1

Description is coming soon

Oligopeptide-2
Est. %0.3
Function
Origin
Oligopeptide-2
Oligopeptide-3
Est. %0.3
Function
Origin
Oligopeptide-3
Acetyl Glutamine
Est. %0.3
Function
Origin
Acetyl Glutamine
Folic Acid
Est. %0.3
Function
Origin
Folic AcidA critical vitamin for the body that needs more research for topical applications.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
Lecithin
Est. %0.3
Function
Origin
LecithinA humectant, emollient, and emulsifier best suited for water-in-oil emulsions. Lecithin can come from sunflowers, soy, and eggs. The downside to lecithin is that it causes an extra burden on the formula’s preservative because it is nutritious.
1,2-Hexanediol
Est. %0.3
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Butylene Glycol
Est. %0.3
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Triethanolamine
Est. %0.3
Function
Origin
TriethanolamineA clear, colorless, and highly viscous liquid, this ingredient is an excellent pH adjuster. When it is necessary to neutralize an acidic solution or to generally increase the pH of a product, triethanolamine is a common choice.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.