Trimay Trimella Niacinamide Ampoule Review

Trimay Trimella Niacinamide Ampoule
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Review

Does Trimay Trimella Niacinamide Ampoule Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Trimay Trimella Niacinamide Ampoule has to offer:
 
  • Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
  • Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Trimay Trimella Niacinamide Ampoule is effective in minimizing wrinkles.
  • Soothing: Trimay Trimella Niacinamide Ampoule contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
  • Antioxidant protection.

Key Benefits of Trimay Trimella Niacinamide Ampoule

 
These are the key benefits you can expect from using Trimay Trimella Niacinamide Ampoule:
 

Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Trimay Trimella Niacinamide Ampoule is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Niacinamide (est. ≈5.0%), Butylene Glycol (est. ≈4.0%) and Pentylene Glycol (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, Trimay Trimella Niacinamide Ampoule has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈5.0%), 
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Trimay Trimella Niacinamide Ampoule also contains Adenosine, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Adenosine provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Rich in Skin-Protecting Antioxidants

We estimate that Trimay Trimella Niacinamide Ampoule is rich (> 3%) in antioxidants, specifically Niacinamide (est. ≈5.0%) and Arbutin (est. ≈3.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

Skin Soothing and Calming Potential

Based on the ingredient list analysis, Trimay Trimella Niacinamide Ampoule is rich (> 5%) in soothing ingredients, particularly Niacinamide (est. ≈5.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Trimay Trimella Niacinamide Ampoule

 
CreamScan AI identified a few things to consider before adding Trimay Trimella Niacinamide Ampoule to your skincare routine:
 

If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Trimay Trimella Niacinamide Ampoule as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Trimay Trimella Niacinamide Ampoule

 
Here’s an overview of the pros and cons of Trimay Trimella Niacinamide Ampoule to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • When used alone: Provides humectant-rich moisturizing ideal for oily skin
  • As part of a routine: A humectant moisturizing boost, beneficial for any skin type
  • Lightweight texture
  • Delivers signficant anti-wrinkle efficacy thanks to Niacinamide
  • Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
  • Potentially soothing, as it contains a high concentration of soothing ingredients, specifically Niacinamide

Cons: 

  • Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants

Ingredients

Est. % Ingredient Origin Functions
75
5
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Niacinamide
Function:
Origin:
Butylene Glycol
Function:
Origin:
Arbutin
Function:
Origin:
Pentylene Glycol
Function:
Origin:
1,2-Hexanediol
Function:
Origin:
Dipropylene Glycol
Function:
Origin:
Tremella Fuciformis Polysaccharide
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Tranexamic Acid
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Allantoin
Function:
Origin:
Adenosine
Function:
Origin:
Tremella Fuciformis (Mushroom) Extract
Function:
Origin:
Disodium EDTA
Function:
Origin:
Glutathione
Function:
Origin:
Dipotassium Glycyrrhizate
Function:
Origin:
Propanediol
Function:
Origin:
Anemarrhena Asphodeloides Root Extract
Function:
Origin:
Glycerin
Function:
Origin:
Lactobacillus
Function:
Origin:
Lactobacillus/Soybean Ferment Extract
Function:
Origin:
Lactobacillus/Rice Ferment
Function:
Origin:
Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate
Function:
Origin:
Saccharomyces/Potato Extract Ferment Filtrate
Function:
Origin:
Aspergillus/Rice Ferment Filtrate
Function:
Origin:
Hyaluronic Acid
Function:
Origin:
Hydrolyzed Hyaluronic Acid
Function:
Origin:
Hydroxypropyltrimonium Hyaluronate
Function:
Origin:
Hydrolyzed Sodium Hyaluronate
Function:
Origin:
Sodium Hyaluronate Crosspolymer
Function:
Origin:
Potassium Hyaluronate
Function:
Origin:
Sodium Acetylated Hyaluronate
Function:
Origin:

Ratings

All humectants
14.9
5
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 14.9 10
10.0
5
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
5
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
All humectants 14.9 10
10
All humectants
14.9
5
4
2
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 5 6
n/a
- 0.3 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
5
Adenosine
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
5
3
0.3
0.3
0.3
0.3
0.3
0.3
All antioxidants 9.8 3 Rich in antioxidants
All antioxidants
9.8
Niacinamide
5
Arbutin
3
Sodium Hyaluronate
0.3
Glutathione
0.3
Lactobacillus
0.3
Hyaluronic Acid
0.3
Hydrolyzed Hyaluronic Acid
0.3
Hydrolyzed Sodium Hyaluronate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
5
0.3
0.3
All soothing 5.6 5 Rich in soothing
All soothing
5.6
5
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Niacinamide
Est. %5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Butylene Glycol
Est. %4
Function
Origin
Butylene Glycol

A clear, colorless liquid humectant that draws moisture to the skin. The humectancy of butylene glycol, owed to its two hydroxyl groups, is quite considerable, although not as powerful as glycerin, which contains three hydroxyl groups.

Arbutin
Est. %3
Function
Origin
ArbutinOne of the few potent anti-pigment compounds found naturally in bearberry or cranberry leaves. When applied to the skin, this ingredient converts into hydroquinone, with tyrosinase inhibiting effects.
Pentylene Glycol
Est. %2
Function
Origin
Pentylene Glycol

A naturally or synthetically derived preservative that exhibits effective antifungal and antibacterial traits. It also acts as a booster for more traditional preservatives. Pentylene glycol can also serve as a moisturizing humectant and solvent.

1,2-Hexanediol
Est. %1.5
Function
Origin
1,2-HexanediolA multi-functional formula helper. It is a well-studied preservtive against bacteria and can help pigments and fragrances disperse evenly in a formula.
Dipropylene Glycol
Est. %1.3
Function
Origin
Dipropylene GlycolA clear, colorless liquid that has several uses. One of its main functions is as a solvent. Dipropylene glycol is also used to reduce the thickness of skincare products.
Tremella Fuciformis Polysaccharide
Est. %1
Function
Origin
Tremella Fuciformis Polysaccharide
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Tranexamic Acid
Est. %0.3
Function
Origin
Tranexamic AcidA synthetic amino acid that is used as an astringent to stop the bleeding from small cuts. It also has proven anti-pigment and redness-reducing effects.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Adenosine
Est. %0.3
Function
Origin
Adenosine

A key molecule responsible for energy transportation, signaling, and enzyme activity. Adenosine is a popular anti-wrinkle ingredient, however, the key study about its anti-wrinkle efficacy (1) does not meet CreamScan Research Evaluation Standards as it is not double-blind.

Tremella Fuciformis (Mushroom) Extract
Est. %0.3
Function
Origin
Tremella Fuciformis (Mushroom) ExtractAn extract derived from an edible mushroom known as snow fungus. It is full of various proteins, fiber, and humectant moisturizing polysaccharides.
Disodium EDTA
Est. %0.3
Function
Origin
Disodium EDTAA synthetic chelator that helps to maintain the look and smell of a product by 'locking up' troublesome metal ions.
Glutathione
Est. %0.3
Function
Origin
GlutathioneA naturally occurring tripeptide that combats free radicals and acts as a reducing agent.
Dipotassium Glycyrrhizate
Est. %0.3
Function
Origin
Dipotassium GlycyrrhizateA licorice root derivative with powerful anti-inflammatory and soothing activities. It is often used as a flavoring agent in lip products.
Propanediol
Est. %0.3
Function
Origin
PropanediolAn excellent solvent capable of mixing water with normally water-insoluble ingredients. It also functions as a humectant due to its water-loving alcohol groups. Propanediol can control the viscosity of a product by reducing its thickness.
Anemarrhena Asphodeloides Root Extract
Est. %0.3
Function
Origin
Anemarrhena Asphodeloides Root Extract
Glycerin
Est. %0.3
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Lactobacillus
Est. %0.3
Function
Origin
LactobacillusA genus of probiotic bacteria. Lactobacillus bacteria are part of the human microflora and their ferment products contain antioxidants.
Lactobacillus/Soybean Ferment Extract
Est. %0.3
Function
Origin
Lactobacillus/Soybean Ferment ExtractA biotechnological ingredient that is essentially soy milk fermented with lactic acid bacteria. It may help to treat skin pigmentation but more research is needed to support this claim.
Lactobacillus/Rice Ferment
Est. %0.3
Function
Origin
Lactobacillus/Rice Ferment
Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate
Est. %0.3
Function
Origin
Saccharomyces/Coix Lacryma-Jobi Ma-yuen Seed Ferment Filtrate
Saccharomyces/Potato Extract Ferment Filtrate
Est. %0.3
Function
Origin
Saccharomyces/Potato Extract Ferment Filtrate
Aspergillus/Rice Ferment Filtrate
Est. %0.3
Function
Origin
Aspergillus/Rice Ferment Filtrate
Hyaluronic Acid
Est. %0.3
Function
Origin
Hyaluronic Acid

A potent, skin-identical humectant moisturizing ingredient that is able to bind water 1000 times its own weight. The anti-aging benefits of hyaluronic acid are due to its ability to stimulate the synthesis of collagen in the skin.

Hydrolyzed Hyaluronic Acid
Est. %0.3
Function
Origin
Hydrolyzed Hyaluronic AcidA smaller-molecule version of the regular hyaluronic acid. It is a powerful humectant that absorbs into the skin and offers moisturizing, smoothing, and anti-wrinkle effects. It is also slightly anti-inflammatory and displays subtle antioxidant properties.
Hydroxypropyltrimonium Hyaluronate
Est. %0.3
Function
Origin
Hydroxypropyltrimonium Hyaluronate
Hydrolyzed Sodium Hyaluronate
Est. %0.3
Function
Origin
Hydrolyzed Sodium HyaluronateA very small-molecule version of regular sodium hyaluronate. It is a powerful humectant skin-identical ingredient that absorbs into the skin and offers plumping, smoothing, and anti-wrinkle effects.
Sodium Hyaluronate Crosspolymer
Est. %0.3
Function
Origin
Sodium Hyaluronate CrosspolymerA modified version of regular hyaluronic acid. It attracts large volumes of water, thereby making it an effective humectant moisturizing ingredient.
Potassium Hyaluronate
Est. %0.3
Function
Origin
Potassium Hyaluronate
Sodium Acetylated Hyaluronate
Est. %0.3
Function
Origin
Sodium Acetylated HyaluronateA chemically modified version of hyaluronic acid. It is more stable and less sticky than regular HA, while still providing the same humectant moisturizing properties (according to the manufacturer). There have been no clinical studies to confirm this.