Ingredients Explained: LORAC PRO Skin Mattifying Primer

Review

Results you may expect from using LORAC PRO Skin Mattifying Primer:

Based on the ingredient analysis by CreamScan, these are the key benefits you can expect from using LORAC PRO Skin Mattifying Primer:

A bit of moisturizing. It has a moisturizing rating of 1.2 out of 10.

How moisturizing is it?

Slightly moisturizing: LORAC PRO Skin Mattifying Primer has a moisturizing rating of 1.2 out of 10.

Is it more humectant or occlusive? This product is purely occlusive, but with a low Occlusivity of 2.4 out of 10. It has zero Humectancy as we didn't find any humectant ingredients on the ingredient list.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Anti-wrinkle efficacy

According to CreamScan analysis, LORAC PRO Skin Mattifying Primer has a zero anti-wrinkle rating.

It contains Palmitoyl Oligopeptide, an ingredient marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Palmitoyl Oligopeptide provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not generate the anti-wrinkle rating.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Preservative
Formula helpers

Other

Est. % The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more The Estimated % is our algorithm-based assumption about an ingredient's concentration in a formula. Learn more	Ingredient	Origin	Functions
50	Cyclopentasiloxane A lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in. Cyclopentasiloxane A lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Formula helper Solvent – a liquid that dissolves other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients.
26.2	Dimethicone Crosspolymer A group of ingredients that are typically added to skincare products to adjust the formula. Dimethicone Crosspolymers stabilize a formula, regulate its thickness and consistency and give the product a velvety feel. Dimethicone Crosspolymer A group of ingredients that are typically added to skincare products to adjust the formula. Dimethicone Crosspolymers stabilize a formula, regulate its thickness and consistency and give the product a velvety feel.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Dispersing – ensures the even distribution of particles. Emulsion stabilizing – increases the stability of a formula. Viscosity controlling – changes the thickness of a product. Formula helper Dispersing – ensures the even distribution of particles. Emulsion stabilizing – increases the stability of a formula. Viscosity controlling – changes the thickness of a product.
13.1	Cyclohexasiloxane A clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin. Cyclohexasiloxane A clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Formula helper Solvent – a liquid that dissolves other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients.
7.2	C12-15 Alkyl Benzoate A synthetic emollient ester. It works to improve the appearance of the skin by filling in the microcracks on the surface, thereby making the skin appear softer and smoother. It imparts a lightweight, velvety feel. C12-15 Alkyl Benzoate A synthetic emollient ester. It works to improve the appearance of the skin by filling in the microcracks on the surface, thereby making the skin appear softer and smoother. It imparts a lightweight, velvety feel.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Formula helper Solvent – a liquid that dissolves other ingredients. Formula helper Solvent – a liquid that dissolves other ingredients.
4.8	Tribehenin A soft, pliable wax that serves as an occlusive moisturizer and emollient. It improves the spreadability of skincare products, including the increased payoff of stick products, and imparts a pleasant, smooth feel upon application. Tribehenin A soft, pliable wax that serves as an occlusive moisturizer and emollient. It improves the spreadability of skincare products, including the increased payoff of stick products, and imparts a pleasant, smooth feel upon application.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Moisturizing (Occlusive), Occlusives are moisturizing ingredients that seal moisture into the skin, forming a water-resistant barrier. Moisturizing (Occlusive), Occlusives are moisturizing ingredients that seal moisture into the skin, forming a water-resistant barrier. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients.
0.3	Ceramide NS A wax-like lipid natural to the skin’s lipid matrix. It is less frequently used but, in combination with other ceramides, can help to restore balance in the skin’s lipid barrier. Ceramide NS A wax-like lipid natural to the skin’s lipid matrix. It is less frequently used but, in combination with other ceramides, can help to restore balance in the skin’s lipid barrier.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier.
0.3	PEG-10 Phytosterol Description is coming soon PEG-10 Phytosterol Description is coming soon	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Formula helper Emulsifying – helps to mix water and oil together. Formula helper Emulsifying – helps to mix water and oil together.
0.3	Palmitoyl Oligopeptide This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity. Palmitoyl Oligopeptide This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity.	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.
0.3	Phenoxyethanol The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless. Phenoxyethanol The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.	Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservatives prevent the growth of bacteria and fungi in a product.

Cyclopentasiloxane

Function:

Origin:

26.2

Dimethicone Crosspolymer

Function:

Origin:

13.1

Cyclohexasiloxane

Function:

Origin:

7.2

C12-15 Alkyl Benzoate

Function:

Origin:

4.8

Tribehenin

Function:

Origin:

0.3

Ceramide NS

Function:

Origin:

0.3

PEG-10 Phytosterol

Function:

Origin:

0.3

Palmitoyl Oligopeptide

Function:

Origin:

0.3

Phenoxyethanol

Function:

Origin:

Ratings

None

Benchmark

Tribehenin

4.8

Benchmark

Moisturizing rating

1.2

Ingredient		Est. %	Benchmark Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity. Sciense based points to which we compare all humectants and all occlusives in a product to calculate its Humectancy and Occlusivity.	Raiting
Humectancy	All humectants	0.0	10	0.0
	None
Occlusivity	All occlusives	4.8	20	2.4
	Tribehenin A soft, pliable wax that serves as an occlusive moisturizer and emollient. It improves the spreadability of skincare products, including the increased payoff of stick products, and imparts a pleasant, smooth feel upon application. Tribehenin A soft, pliable wax that serves as an occlusive moisturizer and emollient. It improves the spreadability of skincare products, including the increased payoff of stick products, and imparts a pleasant, smooth feel upon application.	4.8
Moisturizing rating				1.2

Ingredient	Est. %	Benchmark The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled). The most occlusive product possible is 100% petrolatum (hello Vaseline Jelly). According to studies, hovewer, even 10% petrolatum can achieve almost the same mosturizing effect. The occlusive properties of petrolatum are at least twice as superior as other occlusive ingredients. This is why, in order to match the moisturizing efficacy of 10% petrolatum, a product needs to contain at least 20% of other occlusives. Our benchmark for maximum Occlusivity is 20 (and the petrolatum score is always doubled).	Occlusivity
Tribehenin A soft, pliable wax that serves as an occlusive moisturizer and emollient. It improves the spreadability of skincare products, including the increased payoff of stick products, and imparts a pleasant, smooth feel upon application. Tribehenin A soft, pliable wax that serves as an occlusive moisturizer and emollient. It improves the spreadability of skincare products, including the increased payoff of stick products, and imparts a pleasant, smooth feel upon application.	4.8
All occlusives	4.8	20	2.4

Tribehenin

4.8

Benchmark

Ingredient	Est. %	Benchmark According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more. According to various studies, a formula made up of 10% humectants will significantly increase skin hydration. Some studies also suggest that any further icrease in the consentration of humectants does not translate inty any more hydration and may even be dehydrating. To achieve maximum Humectancy, the product should have humectants with a total score of 10 and more.	Humectancy
None
All humectants	0.0	10	0.0

None

Benchmark

Ingredient	Ingredient anti-wrinkle power Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account. Shows on a scale of 0-10 how effective an ingredient is at reducing wrinkles. Both the Reported Efficacy of the ingredient and the Strength of Evidence are taken into account.	when present at, %	in this formula est. % Some information here Some information here	Rating
Palmitoyl Oligopeptide This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity. Palmitoyl Oligopeptide This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity.	n/a This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating. This ingredient is marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of this ingredient provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards. Therefore, these ingredients do not contribute to the anti-wrinkle rating.	-	0.3	-
Total				0

Palmitoyl Oligopeptide

Ingredient anti-wrinkle power

n/a

when present at, %

in this formula, est. %

0.3

Anti-wrinkle rating

Ingredient	Est. %	Benchmark It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants. It differs from one antioxidant ingredient to another, but, on average, the research suggests that topically applied antioxidants are effective in consentrations of 3% or above. Any product with a total antioxidant score of 3 or more is considered to be reach in antioxidants.	Rich in Antioxidants
None
All antioxidants	0	3	No

None

Benchmark

Ingredient	Est. %	Benchmark The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%. The effective concentration of soothing ingredients varies, but we consider a product rich in soothing ingredients if their estimated concentration is equal to or higher than 5%.	Rating
None
All soothing	0	5	No

None

Benchmark

Ingredients explained

Cyclopentasiloxane
Est. %	50
Function	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A lightweight, fast-spreading emollient that leaves a very soft and silky after-feel on the skin. Supplied as a clear and colorless liquid, cyclopentasiloxane is often used as a solvent to dissolve other silicones in.

Dimethicone Crosspolymer
Est. %	26.2
Function	Dispersing, Dispersing – ensures the even distribution of particles. Dispersing, Dispersing – ensures the even distribution of particles. Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Emulsion Stabilizing, Emulsion stabilizing – increases the stability of a formula. Viscosity Controlling Viscosity controlling – changes the thickness of a product. Viscosity Controlling Viscosity controlling – changes the thickness of a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A group of ingredients that are typically added to skincare products to adjust the formula. Dimethicone Crosspolymers stabilize a formula, regulate its thickness and consistency and give the product a velvety feel.

Cyclohexasiloxane
Est. %	13.1
Function	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A clear silicone fluid with very low viscosity that is commonly used as a solvent and emollient. It has excellent spreadability, rubs in quickly, and leaves a silky smooth after-feel on the skin.

C12-15 Alkyl Benzoate
Est. %	7.2
Function	Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient, Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Solvent Solvent – a liquid that dissolves other ingredients. Solvent Solvent – a liquid that dissolves other ingredients.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A synthetic emollient ester. It works to improve the appearance of the skin by filling in the microcracks on the surface, thereby making the skin appear softer and smoother. It imparts a lightweight, velvety feel.

Tribehenin
Est. %	4.8
Function	Moisturizing (Occlusive), Occlusives are moisturizing ingredients that seal moisture into the skin, forming a water-resistant barrier. Moisturizing (Occlusive), Occlusives are moisturizing ingredients that seal moisture into the skin, forming a water-resistant barrier. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients. Emollient Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch. Emollients are often mistakenly perceived as moisturizing ingredients.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A soft, pliable wax that serves as an occlusive moisturizer and emollient. It improves the spreadability of skincare products, including the increased payoff of stick products, and imparts a pleasant, smooth feel upon application.

Ceramide NS
Est. %	0.3
Function	Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier. Barrier Repair Barrier repair ingredients help to restore the healthy function of the skin’s lipid barrier.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

A wax-like lipid natural to the skin’s lipid matrix. It is less frequently used but, in combination with other ceramides, can help to restore balance in the skin’s lipid barrier.

PEG-10 Phytosterol
Est. %	0.3
Function	Emulsifying Emulsifying – helps to mix water and oil together. Emulsifying Emulsifying – helps to mix water and oil together.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

Description is coming soon

Palmitoyl Oligopeptide
Est. %	0.3
Function	Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles. Anti-Wrinkle Anti-wrinkle ingredients prevent the formation or reduce the appearance of wrinkles.
Origin	Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Botanical, Ingredients derived from plants, mosses, and lichens: extracts, oils, powders, juices and other types of processed plant materials. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic, All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.) Animal Ingredients derived from animals (including birds, fish, crustaceans, mollusks, and insects) or produced by animals (e.g. dairy- and egg-derived ingredients, bee products, silk, pearls, etc.)

This is an old INCI name that can refer to several other peptides. They are all short fragments of collagen or elastin and function as signal molecules, telling the skin to repair and restructure the dermis, resulting in anti-wrinkle activity.

Phenoxyethanol
Est. %	0.3
Function	Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Antimicrobial, Antimicrobials prevent the growth of harmful microorganisms on the skin. Preservative Preservatives prevent the growth of bacteria and fungi in a product. Preservative Preservatives prevent the growth of bacteria and fungi in a product.
Origin	Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure. Synthetic All kinds of ingredients formulated or produced by a chemical process, or those that have a chemical modification in their structure.

The most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.