Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum Review

Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
6Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Rich Skin Soothing icon
in Skin Soothers
Ingredients

Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum Ingredients

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Full Ingredient List (INCI):

Water, Aloe Barbadensis Leaf Juice, Niacinamide, Propylene Glycol, Glycerin, Snail Secretion Filtrate, Cucumis Sativus (Cucumber) Fruit Extract, Sodium Hyaluronate, Phenoxyethanol, Ethylhexylglycerin, Hydroxyethylcellulose, Allantoin
Review

Does Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
✅ Significant anti-wrinkle efficacy. With an anti-wrinkle rating of 6.0 out of 10, Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum is effective in minimizing wrinkles.
✅ Soothing: Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum contains a high concentration of soothing ingredients, which may help to reduce irritation and calm the skin.
✅ Antioxidant protection

  

Key Benefits of Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum

 
These are the key benefits you can expect from using Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum:
 

🔵 Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Aloe Barbadensis Leaf Juice (est. ≈6.0%), Niacinamide (est. ≈5.0%) and Propylene Glycol (est. ≈3.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

📌 Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣 Significant Anti-Wrinkle Efficacy

According to CreamScan analysis, Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum has a high anti-wrinkle rating of 6.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Niacinamide (est. ≈5.0%),
 one of the most effective and well-researched anti-wrinkle ingredients. A clinical study involving 30 participants (Kawada et al.) confirmed that a cream with 4% niacinamide reduced the average depth of wrinkles around the eyes by 9% after 8 weeks of use, compared to a vehicle (the same formulation without niacinamide).
 
Among others, Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum also contains Snail Secretion Filtrate, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Snail Secretion Filtrate provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Snail Secretion Filtrate may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum is rich (> 3%) in antioxidants, specifically Aloe Barbadensis Leaf Juice (est. ≈6.0%) and Niacinamide (est. ≈5.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

🔴 Skin Soothing and Calming Potential

Based on the ingredient list analysis, Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum is rich (> 5%) in soothing ingredients, particularly Aloe Barbadensis Leaf Juice (est. ≈6.0%) and Niacinamide (est. ≈5.0%).

When applied to the skin, compounds of soothing ingredients, such as triglycerides, phospholipids, fatty acids, phenolic compounds, and antioxidants, work together to soothe the skin through various mechanisms: reducing inflammation, promoting wound healing, repairing the skin barrier, and providing antimicrobial and antioxidant activities.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum

 
CreamScan identified a few things to consider before adding Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum to your skincare routine:
 

⚠️ Contains Snail Secretion Filtrate –  a Popular Ingredient with Limited Proven Clinical Efficacy

Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum contains Snail Secretion Filtrate (SSF, SCA), a purified form of snail mucin. Snail Secretion Filtrate is widely promoted for its supposed skincare benefits, including hydration, skin repair, wound healing, and anti-aging. CreamScan conducted an investigation into clinical trials evaluating the potential efficacy of SSF and found no convincing evidence to support its claimed benefits beyond basic moisturization. The full article is available here.

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum

 
Here’s an overview of the pros and cons of Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers signficant anti-wrinkle efficacy thanks to Niacinamide
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
✅ Potentially soothing, as it contains a high concentration of soothing ingredients like Aloe Barbadensis Leaf Juice and Niacinamide
 

⭕ Cons: 

⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants

⚠️ Contains Snail Secretion Filtrate (SSF), a popular ingredient with limited clinical evidence supporting most of its claimed benefits.

   

Summary: Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum
 is specifically effective in treating wrinkles, containing ingredients with solid, robust evidence of anti-wrinkle efficacy.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

Rich in antioxidants, Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation. This product is also formulated with a high concentration of soothing ingredients, offering the potential to calm and comfort irritated skin. Whether you’re experiencing redness, irritation, or general sensitivity, its soothing properties may help restore balance and provide relief.
 
That said, there are some things about Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 

Note that Dermorepubliq 5% Niacinamide + Hyaluronic Acid Sensitive Skin Formula Serum contains Snail Secretion Filtrate (SSF), an ingredient widely promoted for its supposed skincare benefits, including wound healing and anti-aging. However, a CreamScan investigation of clinical evidence found no convincing data supporting these claims.

📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
80
6
5
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Aloe Barbadensis Leaf Juice
Function:
Origin:
Niacinamide
Function:
Origin:
Propylene Glycol
Function:
Origin:
Glycerin
Function:
Origin:
Snail Secretion Filtrate
Function:
Origin:
Cucumis Sativus (Cucumber) Fruit Extract
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Hydroxyethylcellulose
Function:
Origin:
Allantoin
Function:
Origin:

Ratings

All humectants
19.1
6
5
3
2
1.5
1
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 19.1 10
10.0
6
5
3
2
1.5
1
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
5
3
2
1.5
1
0.3
0.3
All humectants 19.1 10
10
All humectants
19.1
6
5
3
2
1.5
1
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
6 /10 4 5 6
n/a
- 1.5 -
Total
6
Niacinamide
6
Ingredient anti-wrinkle power
6 /10
when present at, %
4
in this formula, est. %
5
Snail Secretion Filtrate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Anti-wrinkle rating
6
Ingredient Est. % Benchmark
Rich in Antioxidants
6
5
1
All antioxidants 12 3 Rich in antioxidants
All antioxidants
12
Aloe Barbadensis Leaf Juice
6
Niacinamide
5
Sodium Hyaluronate
1
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
6
5
1.3
0.3
All soothing 12.6 5 Rich in soothing
All soothing
12.6
6
5
1.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Aloe Barbadensis Leaf Juice
Est. %6
Function
Origin
Aloe Barbadensis Leaf JuiceA gelatinous juice from Aloe vera leaves that acts as a powerful humectant, emollient, and antioxidant. It contains enzymes, amino acids, vitamins, and minerals that soothe irritated skin and have wound-healing and anti-inflammatory properties.
Niacinamide
Est. %5
Function
Origin
Niacinamide

Also known as vitamin B3, this ingredient is a true superstar with confirmed moisturizing, anti-acne, hyperpigmentation, and antioxidant benefits. Two studies confirm its significant anti-wrinkle efficacy.

Propylene Glycol
Est. %3
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Glycerin
Est. %2
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Snail Secretion Filtrate
Est. %1.5
Function
Origin
Snail Secretion Filtrate

aka snail mucin, a popular k-beauty ingredient without convincing proof of efficacy.

Cucumis Sativus (Cucumber) Fruit Extract
Est. %1.3
Function
Origin
Cucumis Sativus (Cucumber) Fruit ExtractA soothing, cooling, and emollient extract derived from cucumbers. Cucumber has been used in skincare for centuries and is used to treat skin problems such as eye swelling, sunburn, and itchy and irritated skin.
Sodium Hyaluronate
Est. %1
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Hydroxyethylcellulose
Est. %0.3
Function
Origin
HydroxyethylcelluloseA naturally-derived thickener that can form clear gel textures without the slimy feeling, unlike some other natural gel-formers.
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.