Derma E Anti-Wrinkle Retinol Renewal Cream Review

Derma E Anti-Wrinkle Retinol Renewal Cream
6.8
/ 10
Moisturizing
4.9 Humectancy icon Humectancy
8.8 Occlusivity icon Occlusivity
2.5Anti-wrinkle icon/ 10
Anti-wrinkle
Rich
in Antioxidants
Ingredients

Derma E Anti-Wrinkle Retinol Renewal Cream Ingredients

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Full Ingredient List (INCI):

Water, Carthamus Tinctorius (Safflower) Seed Oil, Stearic Acid, Glycerin, Glyceryl Stearate SE, Cetyl Alcohol, Microcrystalline Cellulose, Cellulose Gum, Persea Gratissima (Avocado) Oil, Sesamum Indicum (Sesame) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Bakuchiol, Retinol, Panthenol, Tocopheryl Acetate, Allantoin, Phenoxyethanol, Ethylhexylglycerin, Fragrance
Review

Does Derma E Anti-Wrinkle Retinol Renewal Cream Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Derma E Anti-Wrinkle Retinol Renewal Cream has to offer:
 
✅ Significant moisturizing. It has a moisturizing rating of 6.8 out of 10.
✅ Modest anti-wrinkle efficacy: Derma E Anti-Wrinkle Retinol Renewal Cream has an anti-wrinkle rating of 2.5 out of 10 so you may expect some, although limited, effect on wrinkles.
✅ Antioxidant protection

  

Key Benefits of Derma E Anti-Wrinkle Retinol Renewal Cream

 
These are the key benefits you can expect from using Derma E Anti-Wrinkle Retinol Renewal Cream:
 

🔵🔵🔵 Rich Moisturizer with the Right Occlusivity for Dry Skin

According to CreamScan analysis, Derma E Anti-Wrinkle Retinol Renewal Cream is highly moisturizing, with a moisturizing rating of 6.8 out of 10.

Is it more humectant or occlusive? Significantly more occlusive. It has a moderate humectancy of 4.9 out of 10, primarily due to the substantial concentration of Glycerin (est. ≈4.0%), and a very high occlusivity of 8.8 out of 10, mainly due to the significant content of Carthamus Tinctorius (Safflower) Seed Oil (est. ≈9.0%) and Stearic Acid (est. ≈6.0%).

This type of product, when used as a standalone moisturizer, can deliver a substantial level of occlusive hydration that is adequate for dry skin. The occlusive profile of Derma E Anti-Wrinkle Retinol Renewal Cream suggests a rich, thick texture, making it perfectly suited for dry skin.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, Derma E Anti-Wrinkle Retinol Renewal Cream has a modest level of anti-wrinkle efficacy, rated 2.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Retinol (est. ≈0.1%),
 the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
 
Among others, Derma E Anti-Wrinkle Retinol Renewal Cream also contains Bakuchiol, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Bakuchiol provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Bakuchiol may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Derma E Anti-Wrinkle Retinol Renewal Cream is rich (> 3%) in antioxidants, specifically Carthamus Tinctorius (Safflower) Seed Oil (est. ≈9.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Derma E Anti-Wrinkle Retinol Renewal Cream

 
CreamScan identified a few things to consider before adding Derma E Anti-Wrinkle Retinol Renewal Cream to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Retinol

This product contains retinol, which offers powerful anti-wrinkle benefits. The mechanism behind retinol’s action is boosting cell turnover. This process exposes new, more delicate skin, making it more vulnerable to sun damage.

As a result, using products with retinol may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To protect the skin, dermatologists recommend applying a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment, along with avoiding direct sun exposure. Retinol should be used at night, as it is sensitive to sunlight and can lose its potency when exposed to UV rays.

📌 Please always check the manufacturer's instructions for using the retinol-containing products, either on their website or product label.

⚠️ Best for Dry Skin - May Be Too Thick for Other Skin Types

With high occlusivity, this product is optimal for dry skin but may be too thick for combination and especially oily skin. Even on normal skin, it can feel too rich depending on the quantity applied, the environment, and individual preferences.

If you have oily, combination, or normal skin and are considering purchasing this product for the first time, it might be a good idea to try a sample before buying.

⚠️ Needs to Be Paired with Extra Humectants for Optimal Moisturizing Efficacy

An ideal moisturizer for any skin type should balance the right level of occlusivity (depending on skin type) with a significant amount of humectants, while Derma E Anti-Wrinkle Retinol Renewal Cream contains a moderate level of humectants.

People with dry skin would definitely benefit from adding more humectants to their moisturizing routine beyond what this product offers. If this is your only moisturizer, it may be worth including a humectant-rich product, such as a serum, in your skincare routine.

Pros & Cons of Derma E Anti-Wrinkle Retinol Renewal Cream

 
Here’s an overview of the pros and cons of Derma E Anti-Wrinkle Retinol Renewal Cream to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

Rich moisturizer with the right level of occlusivity to moisturize dry skin
Rich texture well-suited for dry skin
Offers modest anti-wrinkle efficacy
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to retinol
⚠️ May feel too rich and thick on skin types other than dry
⚠️ Only if used as a standalone moisturizer - needs to be paired with extra humectants for optimal moisturizing efficacy
   

Summary: Derma E Anti-Wrinkle Retinol Renewal Cream

 
Based on the ingredient list analysis, CreamScan AI suggests that Derma E Anti-Wrinkle Retinol Renewal Cream
, as a moisturizer, provides a substantial level of occlusive hydration that is adequate for dry skin, delivered in a rich, thick texture.
 
Derma E Anti-Wrinkle Retinol Renewal Cream contains ingredients with proven evidence of anti-wrinkle efficacy that may provide a modest anti-wrinkle effect. As a result, you can expect a positive, though not very significant, impact on wrinkles.
 
With its high antioxidant content, Derma E Anti-Wrinkle Retinol Renewal Cream helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
That said, there are some things about Derma E Anti-Wrinkle Retinol Renewal Cream worth noting.
 
With its high occlusivity, Derma E Anti-Wrinkle Retinol Renewal Cream is ideal for dry skin but may feel too thick on other skin types. If you have oily, combination, or normal skin, it’s a good idea to try a sample before purchasing.
 
If you use this product as your only moisturizer in a routine, please note that it contains a limited amount of humectants. Regardless of your skin type, adding extra humectants can enhance optimal moisturizing efficacy. Therefore, it may be worth pairing Derma E Anti-Wrinkle Retinol Renewal Cream with a humectant-rich product, such as a serum, in your skincare routine.
 
This product contains retinol, the most powerful and well-researched non-prescription anti-wrinkle ingredient. However, retinol can make your skin more prone to sun damage and increase sensitivity, so it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
65
9
6
4
3
2.5
2
1.5
1.3
1
0.3
0.3
0.1
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Carthamus Tinctorius (Safflower) Seed Oil
Function:
Origin:
Stearic Acid
Function:
Origin:
Glycerin
Function:
Origin:
Glyceryl Stearate SE
Function:
Origin:
Cetyl Alcohol
Function:
Origin:
Microcrystalline Cellulose
Function:
Origin:
Cellulose Gum
Function:
Origin:
Persea Gratissima (Avocado) Oil
Function:
Origin:
Sesamum Indicum (Sesame) Seed Oil
Function:
Origin:
Helianthus Annuus (Sunflower) Seed Oil
Function:
Origin:
Bakuchiol
Function:
Origin:
Retinol
Function:
Origin:
Panthenol
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Allantoin
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
4.9
4
0.3
0.3
0.3
Benchmark
10
All occlusives
17.6
9.0
6.0
1.3
1.0
0.3
Benchmark
20
Moisturizing rating
6.8
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 4.9 10
4.9
4
0.3
0.3
0.3
Occlusivity All occlusives 17.6 20
8.8
9.0
6.0
1.3
1.0
0.3
Moisturizing rating
6.8
Ingredient Est. % Benchmark Humectancy
4
0.3
0.3
0.3
All humectants 4.9 10
4.9
All humectants
4.9
4
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
9
6
1.3
1
0.3
All occlusives 17.6 20
8.8
All occlusives
17.6
9.0
6.0
1.3
1.0
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.1 2.5
n/a
- 0.3 -
Total
2.5
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Bakuchiol
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
2.5
Ingredient Est. % Benchmark
Rich in Antioxidants
9
1.3
0.3
0.3
All antioxidants 10.9 3 Rich in antioxidants
All antioxidants
10.9
Carthamus Tinctorius (Safflower) Seed Oil
9
Persea Gratissima (Avocado) Oil
1.3
Bakuchiol
0.3
Tocopheryl Acetate
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
All soothing 0.6 5 No
All soothing
0.6
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %65
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Carthamus Tinctorius (Safflower) Seed Oil
Est. %9
Function
Origin
Carthamus Tinctorius (Safflower) Seed OilA fatty oil pressed from safflower seeds that is used as an occlusive moisturizer and emollient. It contains unusually high amounts of linoleic acid (up to 70%), as well as antioxidant compounds such as vitamin E, phytosterols, and phenolics.
Stearic Acid
Est. %6
Function
Origin
Stearic AcidA saturated fatty acid found in vegetable butter and animal fats. It is an occlusive moisturizing and emollient ingredient and also helps to maintain the barrier function of the skin.
Glycerin
Est. %4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Glyceryl Stearate SE
Est. %3
Function
Origin
Glyceryl Stearate SEAn emulsifier, where the SE stands for self-emulsifying. Emulsions containing glyceryl stearate SE often impart a smooth, velvety feel upon the skin.
Cetyl Alcohol
Est. %2.5
Function
Origin
Cetyl AlcoholA waxy solid fatty alcohol derived from palm oil. It is most commonly used as a co-emulsifier and affects the final aesthetic of the product, leaving a soft and silky feeling on the skin. Cetyl alcohol is also used as a viscosity controlling agent.
Microcrystalline Cellulose
Est. %2
Function
Origin
Microcrystalline CelluloseA plant-based ingredient derived from cellulose. The rough version of microcrystalline cellulose is used in scrubs instead of plastic microbeads and the finer version is used as a thickener and stabilizer and readily absorbs oil and sweat.
Cellulose Gum
Est. %1.5
Function
Origin
Cellulose GumA polymer that is derived from its namesake, cellulose, which is plant-based. It has many formula-helper benefits, including thickening and product stabilization.
Persea Gratissima (Avocado) Oil
Est. %1.3
Function
Origin
Persea Gratissima (Avocado) OilA fatty oil expressed from the fleshy part of an avocado, used in skincare for its excellent emollient and occlusive moisturizing properties. Avocado oil contains fatty acids, notably oleic acid (up to 80%), squalene, vitamin E, and carotenoids.
Sesamum Indicum (Sesame) Seed Oil
Est. %1
Function
Origin
Sesamum Indicum (Sesame) Seed OilAn emollient fatty oil expressed from sesame seeds. It is made up majorly of unsaturated fatty acids, linoleic acid (up to 45%), and oleic acid (up to 38%). Sesame oil is an occlusive moisturizer that is rich in antioxidant compounds.
Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
Helianthus Annuus (Sunflower) Seed OilA fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Bakuchiol
Est. %0.3
Function
Origin
BakuchiolA newly discovered bioactive obtained from the seeds of Babchi. It boosts collagen production like retinol, but with fewer side effects. Its effects include reduced wrinkles and faded pigmentation.
Retinol
Est. %0.1
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.