Derma E Anti-Wrinkle Retinol Concentrated Serum Review

Derma E Anti-Wrinkle Retinol Concentrated Serum
5.1
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.2 Occlusivity icon Occlusivity
10Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does Derma E Anti-Wrinkle Retinol Concentrated Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Derma E Anti-Wrinkle Retinol Concentrated Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.1 out of 10.
✅ Potent anti-wrinkle effect with the highest possible efficacy rating. With an anti-wrinkle rating of 10.0 out of 10, Derma E Anti-Wrinkle Retinol Concentrated Serum is highly potent in reducing wrinkles.

  

Key Benefits of Derma E Anti-Wrinkle Retinol Concentrated Serum

 
These are the key benefits you can expect from using Derma E Anti-Wrinkle Retinol Concentrated Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Derma E Anti-Wrinkle Retinol Concentrated Serum is quite moisturizing, with a moisturizing rating of 5.1 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.2 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈12.4%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣🟣🟣 Potent Anti-Wrinkle Efficacy

According to CreamScan analysis, Derma E Anti-Wrinkle Retinol Concentrated Serum has a maximum anti-wrinkle rating of 10.0 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Retinol (est. ≈0.5%),
 the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
 
Among others, Derma E Anti-Wrinkle Retinol Concentrated Serum also contains Bakuchiol, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Bakuchiol provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that Bakuchiol may reduce wrinkles, its efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Derma E Anti-Wrinkle Retinol Concentrated Serum

 
CreamScan AI identified a few things to consider before adding Derma E Anti-Wrinkle Retinol Concentrated Serum to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Retinol

This product contains retinol, which offers powerful anti-wrinkle benefits. The mechanism behind retinol’s action is boosting cell turnover. This process exposes new, more delicate skin, making it more vulnerable to sun damage.

As a result, using products with retinol may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To protect the skin, dermatologists recommend applying a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment, along with avoiding direct sun exposure. Retinol should be used at night, as it is sensitive to sunlight and can lose its potency when exposed to UV rays.

❗️Please always check the manufacturer's instructions for using the retinol-containing products, either on their website or product label.

Pros & Cons of Derma E Anti-Wrinkle Retinol Concentrated Serum

 
Here’s an overview of the pros and cons of Derma E Anti-Wrinkle Retinol Concentrated Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Delivers potent anti-wrinkle efficacy with the highest possible rating of 10 out of 10 thanks to Retinol
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to retinol
   

Summary: Derma E Anti-Wrinkle Retinol Concentrated Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Derma E Anti-Wrinkle Retinol Concentrated Serum
 is highly effective in treating wrinkles, featuring ingredients with solid, robust evidence of anti-wrinkle efficacy, in concentrations that may deliver a significant anti-wrinkle effect.
 

When used alone, it delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.

That said, there are some things about Derma E Anti-Wrinkle Retinol Concentrated Serum worth noting.
 
This product contains retinol, the most powerful and well-researched non-prescription anti-wrinkle ingredient. However, retinol can make your skin more prone to sun damage and increase sensitivity, so it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment.
 
❗️ Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible.

 

Ingredients

Est. % Ingredient Origin Functions
80
12.4
0.5
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Retinol
Function:
Origin:
Bakuchiol
Function:
Origin:
Astaxanthin
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Punica Granatum Fruit Extract
Function:
Origin:
Aspalathus Linearis Extract
Function:
Origin:
Allantoin
Function:
Origin:
Sodium PCA
Function:
Origin:
Phospholipids
Function:
Origin:
Caprylic/Capric Triglyceride
Function:
Origin:
Carbomer
Function:
Origin:
Leuconostoc/Radish Root Ferment Filtrate
Function:
Origin:
Potassium Hydroxide
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Sodium Benzoate
Function:
Origin:
Polysorbate 20
Function:
Origin:
Phenoxyethanol
Function:
Origin:

Ratings

All humectants
13.3
12.4
0.3
0.3
0.3
Benchmark
10
All occlusives
0.3
0.3
Benchmark
20
Moisturizing rating
5.1
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 13.3 10
10.0
12.4
0.3
0.3
0.3
Occlusivity All occlusives 0.3 20
0.2
0.3
Moisturizing rating
5.1
Ingredient Est. % Benchmark Humectancy
12.4
0.3
0.3
0.3
All humectants 13.3 10
10
All humectants
13.3
12.4
0.3
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
All occlusives 0.3 20
0.2
All occlusives
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.5 10
n/a
- 0.3 -
Total
10
Retinol
10
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.5
Bakuchiol
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
10
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
All antioxidants 1.2 3 No
All antioxidants
1.2
Bakuchiol
0.3
Astaxanthin
0.3
Sodium Hyaluronate
0.3
Punica Granatum Fruit Extract
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
0.3
0.3
All soothing 0.6 5 No
All soothing
0.6
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %12.4
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Retinol
Est. %0.5
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Bakuchiol
Est. %0.3
Function
Origin
BakuchiolA newly discovered bioactive obtained from the seeds of Babchi. It boosts collagen production like retinol, but with fewer side effects. Its effects include reduced wrinkles and faded pigmentation.
Astaxanthin
Est. %0.3
Function
Origin
AstaxanthinA red natural pigment from the family of antioxidant carotenoids that occurs in many natural sources such as lobster and algae. It is mainly used as a colorant and soothing ingredient.
Sodium Hyaluronate
Est. %0.3
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Punica Granatum Fruit Extract
Est. %0.3
Function
Origin
Punica Granatum Fruit ExtractA pomegranate fruit extract that contains antioxidant polyphenols and a rare emollient punicic acid. It is aimed at dry, irritated skin.
Aspalathus Linearis Extract
Est. %0.3
Function
Origin
Aspalathus Linearis Extract
Allantoin
Est. %0.3
Function
Origin
AllantoinA fluffy, white powder that acts as a humectant due to its water-loving chemistry and as an exfoliant that helps to remove dead skin cells. It has also been shown to be very soothing to irritated and inflamed skin.
Sodium PCA
Est. %0.3
Function
Origin
Sodium PCAOne of the most important parts of the skin's Natural Moisturizing Factor, a mixture of various compounds that keeps the skin’s surface well hydrated. Sodium PCA is used in skincare for its fantastic humectant properties.
Phospholipids
Est. %0.3
Function
Origin
PhospholipidsA large group of lipids that are an essential component of every single cell membrane in the body. They have excellent emollient properties. Phospholipids are also utilized in the manufacturing of ‘fancy’ formulations such as liposomes.
Caprylic/Capric Triglyceride
Est. %0.3
Function
Origin
Caprylic/Capric TriglycerideA natural occlusive moisturizing and emollient ingredient, it is a blend of glycerin and two fatty acids, caprylic and capric acid. It creates an oil-based protective layer on the skin, thereby preventing water loss.
Carbomer
Est. %0.3
Function
Origin
CarbomerA synthetic ingredient with the ability to gel water. When used in emulsions, such as lotions and creams, carbomer can also act as an emulsion stabilizer.
Leuconostoc/Radish Root Ferment Filtrate
Est. %0.3
Function
Origin
Leuconostoc/Radish Root Ferment FiltrateA biotechnological fermentation ingredient that is created by feeding radish root to Leuconostoc kimchii. It allegedly contains organic acids and a mixture of peptides known as bacteriocins – which have antimicrobial activity.
Potassium Hydroxide
Est. %0.3
Function
Origin
Potassium HydroxideA very alkaline ingredient, meaning that it has a high pH. Potassium hydroxide is therefore useful in bringing a low pH in a cosmetic product up to a more neutral, skin-safe level.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Sodium Benzoate
Est. %0.3
Function
Origin
Sodium BenzoateA preservative that usually works in combination with other preservatives. It has to be at low pH (<5.5) to be effective.
Polysorbate 20
Est. %0.3
Function
Origin
Polysorbate 20A viscous, amber-colored liquid that functions as a solubilizer to disperse small amounts of oil into a large water phase. Polysorbate 20 is frequently used to solubilize fragrance oils into water-based emulsions.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.