Derma E Anti-Aging Regenerative Serum Review

Derma E Anti-Aging Regenerative Serum
5.2
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.4 Occlusivity icon Occlusivity
Rich
in Antioxidants
Ingredients

Derma E Anti-Aging Regenerative Serum Ingredients

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Full Ingredient List (INCI):

Water, Glycerin, Camellia Sinensis Leaf Extract, Coco-Caprylate, Xanthan Gum, Diheptyl Succinate, Capryloyl Glycerin/Sebacic Acid Copolymer, Glycolic Acid, Panthenol, Retinyl Palmitate, Tocopheryl Acetate, Persea Gratissima (Avocado) Oil, Sesamum Indicum (Sesame) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Glyceryl Stearate, Potassium Cetyl Phosphate, Glyceryl Stearate Citrate, Phenoxyethanol, Ethylhexylglycerin, Fragrance
Review

Does Derma E Anti-Aging Regenerative Serum Work?

 
According to CreamScan's analysis of the ingredient list, here’s what Derma E Anti-Aging Regenerative Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.2 out of 10.
✅ Antioxidant protection

  

Key Benefits of Derma E Anti-Aging Regenerative Serum

 
These are the key benefits you can expect from using Derma E Anti-Aging Regenerative Serum:
 

🔵 Lightweight Humectant Moisturizer Ideal for Oily Skin

According to CreamScan analysis, Derma E Anti-Aging Regenerative Serum is quite moisturizing, with a moisturizing rating of 5.2 out of 10.

Is it more humectant or occlusive? Significantly more humectant. It has a low occlusivity of 0.4 out of 10 and a maximum humectancy of 10 out of 10, primarily due to the high content of Glycerin (est. ≈6.0%) and Camellia Sinensis Leaf Extract (est. ≈4.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, offering significant hydration in a lightweight, fast-absorbing formula with a minimal amount of occlusive ingredients.

It’s also a great choice for people with normal skin who prefer lightweight moisturizers.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🍀 Rich in Skin-Protecting Antioxidants

We estimate that Derma E Anti-Aging Regenerative Serum is rich (> 3%) in antioxidants, specifically Camellia Sinensis Leaf Extract (est. ≈4.0%).

A key benefit of antioxidants is their ability to reduce oxidative stress caused by free radicals and therefore prevent accelerated skin aging. Studies also show that antioxidants can protect against environmental damage such as UV radiation and pollution, and help reduce inflammation and skin redness.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Derma E Anti-Aging Regenerative Serum

 
CreamScan identified a few things to consider before adding Derma E Anti-Aging Regenerative Serum to your skincare routine:
 

⚠️ May Increase Skin Photosensitivity Due to Glycolic Acid

This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. Its action works by removing dead skin cells, revealing new, more delicate skin that is particularly vulnerable to sun damage.

As a result, using products with glycolic acid, regardless of concentration, may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To counteract this increased sun sensitivity, apply a broad-spectrum sunscreen with at least SPF 30 daily to protect your skin during glycolic acid treatment.

📌 Please always check the manufacturer's instructions for using the product, either on their website or product label.

⚠️ Questionable anti-wrinkle efficacy

If one of your main reasons for choosing Derma E Anti-Aging Regenerative Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, it currently has a zero anti-wrinkle rating.

It contains Camellia Sinensis Leaf Extract and Retinyl Palmitate, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.

While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.

Therefore, these ingredients do not generate the anti-wrinkle rating.

📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Pros & Cons of Derma E Anti-Aging Regenerative Serum

 
Here’s an overview of the pros and cons of Derma E Anti-Aging Regenerative Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
✅ Rich in antioxidants that combat oxidative stress associated with accelerated skin aging and defend against environmental damage
 

⭕ Cons: 

⚠️ May increase skin photosensitivity due to glycolic acid
⚠️ Questionable anti-wrinkle efficacy
   

Summary: Derma E Anti-Aging Regenerative Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Derma E Anti-Aging Regenerative Serum
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
With its high antioxidant content, Derma E Anti-Aging Regenerative Serum helps protect against free radical damage and offers multiple benefits for all skin types, including preventing premature aging, defending against environmental damage, and calming inflammation.
 
That said, there are some things about Derma E Anti-Aging Regenerative Serum worth noting.
 
This product contains glycolic acid, a popular AHA known for its ability to exfoliate and brighten the skin. However, glycolic acid - regardless of concentration - can increase skin sensitivity, making it more prone to sunburn or irritation when exposed to UV rays. Therefore, it’s recommended to use a broad-spectrum sunscreen with at least SPF 30 during glycolic acid treatment.
 
If one of your main reasons for considering Derma E Anti-Aging Regenerative Serum is its potential anti-aging effects, please note that, according to CreamScan analysis, its anti-wrinkle efficacy is questionable. None of the ingredients in this product provide substantial evidence of their anti-wrinkle efficacy according to CreamScan Research Evaluation Standards.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredient Breakdown

Est. % Ingredient Origin Functions
80
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Glycerin
Function:
Origin:
Camellia Sinensis Leaf Extract
Function:
Origin:
Coco-Caprylate
Function:
Origin:
Xanthan Gum
Function:
Origin:
Diheptyl Succinate
Function:
Origin:
Capryloyl Glycerin/Sebacic Acid Copolymer
Function:
Origin:
Glycolic Acid
Function:
Origin:
Panthenol
Function:
Origin:
Retinyl Palmitate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Persea Gratissima (Avocado) Oil
Function:
Origin:
Sesamum Indicum (Sesame) Seed Oil
Function:
Origin:
Helianthus Annuus (Sunflower) Seed Oil
Function:
Origin:
Glyceryl Stearate
Function:
Origin:
Potassium Cetyl Phosphate
Function:
Origin:
Glyceryl Stearate Citrate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Fragrance
Function:
Origin:

Ratings

All humectants
10.6
6
4
0.3
0.3
Benchmark
10
All occlusives
0.9
0.3
0.3
0.3
Benchmark
20
Moisturizing rating
5.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 10.6 10
10.0
6
4
0.3
0.3
Occlusivity All occlusives 0.9 20
0.4
0.3
0.3
0.3
Moisturizing rating
5.2
Ingredient Est. % Benchmark Humectancy
6
4
0.3
0.3
All humectants 10.6 10
10
All humectants
10.6
6
4
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
0.3
0.3
0.3
All occlusives 0.9 20
0.4
All occlusives
0.9
0.3
0.3
0.3
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
n/a
- 4 -
n/a
- 0.3 -
Total
0
Camellia Sinensis Leaf Extract
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
4
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
0.3
Anti-wrinkle rating
0
Ingredient Est. % Benchmark
Rich in Antioxidants
4
0.3
0.3
All antioxidants 4.6 3 Rich in antioxidants
All antioxidants
4.6
Camellia Sinensis Leaf Extract
4
Tocopheryl Acetate
0.3
Persea Gratissima (Avocado) Oil
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
4
0.3
All soothing 4.3 5 No
All soothing
4.3
4
0.3
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Glycerin
Est. %6
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Camellia Sinensis Leaf Extract
Est. %4
Function
Origin
Camellia Sinensis Leaf Extract

An antioxidant green tea extract. In the deeper layers, it slows down the destruction of collagen, elastin, and hyaluronic acid – thus delaying the signs of aging. It also acts as an anti-acne, soothing, moisturizing, and emollient ingredient.

Coco-Caprylate
Est. %3
Function
Origin
Coco-CaprylateA naturally-derived or synthetically produced oil with a very light feel. An alternative to silicones, this ingredient spreads quickly and doesn't leave a residue on skin.
Xanthan Gum
Est. %2
Function
Origin
Xanthan GumA natural multi-functional ingredient that originates from fermented sugars. Xanthan gum acts as a viscosity-building agent to thicken skincare products. It is also an excellent stabilizer and works well to hold other ingredients together.
Diheptyl Succinate
Est. %1.5
Function
Origin
Diheptyl SuccinateA naturally-derived ingredient made from castor oil and wheat . Usually it is part of an ingredient blend as an alternative to silicones. It helps improve the spread of a product and reduce tackiness while remaining light on the skin.
Capryloyl Glycerin/Sebacic Acid Copolymer
Est. %1.3
Function
Origin
Capryloyl Glycerin/Sebacic Acid CopolymerA naturally-derived film-former that increases water resistance of a product. It is also referred to as an alternative to dimethicone.
Glycolic Acid
Est. %1
Function
Origin
Glycolic Acid

The second most used AHA (after lactic acid) known for its potent exfoliating and smoothing effects. It increases skin cell turnover, which is beneficial for treating acne. When used in peels, glycolic acid has confirmed anti-wrinkle efficacy.

Panthenol
Est. %0.3
Function
Origin
PanthenolA popular soothing and moisturizing derivative of vitamin B5. Panthenol is particularly beneficial for dry, flaking, burned, or damaged skin. It is used to alleviate the symptoms of a rash, dermatitis, eczema, chapped lips, and sunburn.
Retinyl Palmitate
Est. %0.3
Function
Origin
Retinyl Palmitate

An esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but lacks clinical proves of its anti-aging and acne-reducing efficacy.

Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Persea Gratissima (Avocado) Oil
Est. %0.3
Function
Origin
Persea Gratissima (Avocado) OilA fatty oil expressed from the fleshy part of an avocado, used in skincare for its excellent emollient and occlusive moisturizing properties. Avocado oil contains fatty acids, notably oleic acid (up to 80%), squalene, vitamin E, and carotenoids.
Sesamum Indicum (Sesame) Seed Oil
Est. %0.3
Function
Origin
Sesamum Indicum (Sesame) Seed OilAn emollient fatty oil expressed from sesame seeds. It is made up majorly of unsaturated fatty acids, linoleic acid (up to 45%), and oleic acid (up to 38%). Sesame oil is an occlusive moisturizer that is rich in antioxidant compounds.
Helianthus Annuus (Sunflower) Seed Oil
Est. %0.3
Function
Origin
Helianthus Annuus (Sunflower) Seed OilA fatty oil expressed from sunflower seeds and one of the most commonly used oils in skincare. It has great emollient and occlusive moisturizing properties. Sunflower oil is one of the richest sources of vitamin E – an important skin antioxidant.
Glyceryl Stearate
Est. %0.3
Function
Origin
Glyceryl StearateAn emollient and emulsifier typically derived from vegetable sources through a chemical reaction with glycerin. It provides stability, texture, and consistency to formulations. Its main function is to allow oil and water to mix.
Potassium Cetyl Phosphate
Est. %0.3
Function
Origin
Potassium Cetyl PhosphateA powerful emulsifier that can even mix particularly problematic water and oil blends. It is also a surfactant perfect for cleansing products that effectively rinse off oil and dirt particles from the surface of the skin.
Glyceryl Stearate Citrate
Est. %0.3
Function
Origin
Glyceryl Stearate CitrateAn ingredient composed of citric acid, stearic acid, and glycerin. Glyceryl stearate citrate acts as an emollient in skincare products, making the skin appear smooth and pleasant to the touch.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Fragrance
Est. %0.3
Function
Origin
FragranceUnder trade secret law, manufacturers have the right not to disclose what exactly went into the fragrance and use the unspecific word Fragrance or Parfum instead. Many fragrances are highly allergenic.