Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum Review

Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum
5.0
/ 10
Moisturizing
10.0 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
0.8Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum has to offer:
 
✅ Strong humectant moisturizing. This lightweight, humectant-rich product, ideal for oily skin, has a moisturizing rating of 5.0 out of 10.
✅ Slight anti-wrinkle effect: Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum has an anti-wrinkle rating of 0.8 out of 10, so you may expect a positive, although insignificant, effect on wrinkles.

  

Key Benefits of Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum

 
These are the key benefits you can expect from using Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum:
 

🔵 Lightweight Purely Humectant Moisturizing, Ideal for Oily Skin

According to CreamScan analysis, Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum is quite moisturizing, with a moisturizing rating of 5.0 out of 10.

Is it more humectant or occlusive? It is purely humectant. It has zero occlusivity (we didn't find any occlusive ingredients on the ingredient list) and a maximum humectancy of 10 out of 10, primarily due to the high content of Sodium Lactate (est. ≈6.0%), Gluconolactone (est. ≈4.0%) and Glycerin (est. ≈2.0%).

This humectant-rich product, when used alone as a moisturizer, is ideal for oily skin, providing significant hydration in a lightweight, fast-absorbing formula without any occlusive ingredients.

📌 Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

💧 A Humectant Boost for Any Skincare Routine

But it’s not limited to oily skin - such a humectant boost will also positively contribute to the moisturizing efficacy of any skincare routine when used as a step before applying the main moisturizer. This type of formulation is typically used in serums, where a light, fast-absorbing texture is key.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

🟣 Slight Anti-Wrinkle Efficacy

According to CreamScan analysis, Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum has a slight anti-wrinkle rating of 0.8 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Sodium Salicylate (est. ≈0.3%),
 a sodium salt of salicylic acid, with moderate anti-wrinkle efficacy confirmed by a single clinical study involving 30 participants (Merinville et al.). This study found that a cream containing 1% sodium salicylate reduced the average depth of periorbital wrinkles by 7% after 8 weeks of use, compared to a vehicle (the same formulation without sodium salicylate).
 
Among others, Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum also contains contains Gluconolactone and Lactobionic Acid, two ingredients often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of these ingredients provide insufficient evidence of efficacy according to CreamScan Research Evaluation Standards.
 
While this does not categorically rule out the possibility that these ingredients may reduce wrinkles, their efficacy is not supported by convincing, vehicle-controlled, double-blind clinical studies - at least none that were available to the CreamScan team at the time of publication.
 
Therefore, these ingredients do not contribute to the anti-wrinkle rating.
 
📌 Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some additional anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

📌 Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum

 
CreamScan AI identified a few things to consider before adding Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum to your skincare routine:
 

⚠️ If It’s Your Only Moisturizer, It Needs to Be Paired with Some Occlusives

While humectants are highly effective at attracting water to the skin, studies (J. N. Kraft, C. W. Lynde) suggest they may not be efficient when used alone.

One major drawback of purely humectant moisturization is that the water attracted by humectants to the upper layers of the skin can evaporate completely into the environment through transepidermal water loss (TEWL). Adding occlusive ingredients helps seal this moisture into the skin and prevent further water loss.

If you’re using Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum as your only moisturizer, consider pairing it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones. These work alongside humectants to create a protective barrier, locking in hydration and ensuring longer-lasting moisturization. The amount of occlusive needed depends on your skin type - the drier the skin, the more occlusives it requires.

If this product is used not as a standalone moisturizer but as part of your skincare routine, such as a toner or serum, it should be applied before your main moisturizer (unless it's a sunscreen), which will provide the necessary occlusivity on top of it.

Pros & Cons of Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum

 
Here’s an overview of the pros and cons of Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum to help you decide if it’s the right choice for your skincare routine:
 

🟩 Pros:

✅ When used alone: Provides humectant-rich moisturizing ideal for oily skin
✅ As part of a routine: A humectant moisturizing boost, beneficial for any skin type
✅ Lightweight texture
Provides slight anti-wrinkle efficacy
 

⭕ Cons: 

⚠️ Only if used as a standalone moisturizer - it needs to be paired with occlusives to seal in humectants
   

Summary: Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum

 
Based on the ingredient list analysis, CreamScan AI suggests that Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum
, when used alone, delivers lightweight, humectant-rich moisturizing, making it ideal for oily skin. As part of a moisturizing routine, it provides a humectant boost, beneficial for all skin types.
 
Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum contains ingredients with proven evidence of anti-wrinkle efficacy that may offer a slight anti-wrinkle effect. As a result, you can expect a positive, though relatively minimal, impact on wrinkles.
 
 
That said, there are some things about Biologique Recherche Serum 3R - Renewing, Regenerating, and Restructuring Facial Serum worth noting.
 
Looking at its moisturizing profile, we found that it doesn’t contain any occlusive ingredients, potentially allowing the moisture attracted to the skin by humectants to evaporate. Therefore, if it’s used as the only moisturizer in a routine, it’s recommended to pair it with one that contains at least some occlusive ingredients, such as oils, butters, or silicones.
 
📌 Fact check. At CreamScan, we are committed to accuracy and fairness. If you spot any errors or something that doesn’t seem right, please click here to let us know. We regularly update the ingredient lists and monitor the latest research on ingredient efficacy to ensure that our information remains as complete and precise as possible. The information provided here is for informational purposes only and does not substitute professional advice. We do not guarantee the efficacy or safety of any product, as individual results may vary.

 

Ingredients

Est. % Ingredient Origin Functions
75
6
4
3
2
1.5
1.3
1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Sodium Lactate
Function:
Origin:
Gluconolactone
Function:
Origin:
Salix Alba (Willow) Bark Extract
Function:
Origin:
Glycerin
Function:
Origin:
Propylene Glycol
Function:
Origin:
Alpha-Glucan Oligosaccharide
Function:
Origin:
Lactobionic Acid
Function:
Origin:
Sodium Gluconate
Function:
Origin:
Sodium Salicylate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Hydrolyzed Opuntia Ficus-Indica Flower Extract
Function:
Origin:
Biosaccharide Gum-2
Function:
Origin:
Pichia Anomala Extract
Function:
Origin:
PVP
Function:
Origin:
Juglans Regia (Walnut) Seed Extract
Function:
Origin:
Opuntia Ficus-Indica Stem Extract
Function:
Origin:
Vaccinium Macrocarpon (Cranberry) Fruit Extract
Function:
Origin:
Tannic Acid
Function:
Origin:
Ethylhexylglycerin
Function:
Origin:
Sambucus Nigra Flower Extract
Function:
Origin:
Terminalia Catappa Leaf Extract
Function:
Origin:
Sodium Metabisulfite
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Potassium Sorbate
Function:
Origin:
Diaminopropionoyl Tripeptide-33
Function:
Origin:

Ratings

All humectants
15.1
6
4
2
1.5
1
0.3
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
5.0
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 15.1 10
10.0
6
4
2
1.5
1
0.3
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
5.0
Ingredient Est. % Benchmark Humectancy
6
4
2
1.5
1
0.3
0.3
All humectants 15.1 10
10
All humectants
15.1
6
4
2
1.5
1
0.3
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
2.5 /10 1 0.3 0.8
n/a
- 4 -
n/a
- 1 -
Total
0.8
Sodium Salicylate
0.8
Ingredient anti-wrinkle power
2.5 /10
when present at, %
1
in this formula, est. %
0.3
Gluconolactone
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
4
Lactobionic Acid
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1
Anti-wrinkle rating
0.8
Ingredient Est. % Benchmark
Rich in Antioxidants
0.3
0.3
0.3
0.3
0.3
All antioxidants 1.5 3 No
All antioxidants
1.5
Opuntia Ficus-Indica Stem Extract
0.3
Vaccinium Macrocarpon (Cranberry) Fruit Extract
0.3
Tannic Acid
0.3
Sambucus Nigra Flower Extract
0.3
Sodium Metabisulfite
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
3
0.3
0.3
All soothing 3.6 5 No
All soothing
3.6
3
0.3
0.3
Benchmark
5

Ingredients explained

Water
Est. %75
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Sodium Lactate
Est. %6
Function
Origin
Sodium LactateA sodium salt of lactic acid. Its main function is as a humectant but it can also serve as a pH adjuster. Additionally, sodium lactate can also be used as a chemical exfoliant due to its close chemical relation to lactic acid.
Gluconolactone
Est. %4
Function
Origin
GluconolactoneA PHA derived from glucose. It has exfoliating and humectant properties and acts as a penetration enhancer for other ingredients. It has also been shown to assist in the treatment of acne and the prevention of photoaging.
Salix Alba (Willow) Bark Extract
Est. %3
Function
Origin
Salix Alba (Willow) Bark ExtractA potent, soothing extract from the bark of the white willow. It has potent anti-inflammatory effects due to its salicin content. Tannins from the willow bark extract have astringent effects and can aid in the skin’s healing process.
Glycerin
Est. %2
Function
Origin
Glycerin

The most popular moisturizing ingredient in the world. It is a powerful humectant – cheap yet very effective.

Propylene Glycol
Est. %1.5
Function
Origin
Propylene GlycolA clear, thick, odorless liquid of synthetic origin. Its main function is to stabilize cosmetic products exposed to varying temperatures. It is also a moderately strong humectant with similar properties to glycerin.
Alpha-Glucan Oligosaccharide
Est. %1.3
Function
Origin
Alpha-Glucan OligosaccharideA sugar-derived ingredient thought to provide protective benefits to the skin's microbiome which keeps skin feeling and looking healthy.
Lactobionic Acid
Est. %1
Function
Origin
Lactobionic AcidA very gentle and non-irritating PHA derived from lactic acid. It has exfoliating and humectant properties and can improve skin elasticity.
Sodium Gluconate
Est. %0.3
Function
Origin
Sodium GluconateA chelating ingredient that ensures that the harmful metal ions in a formula are unreactive. It also protects other ingredients from degrading.
Sodium Salicylate
Est. %0.3
Function
Origin
Sodium Salicylate

A synthetic derivative of salicylic acid with confirmed anti-wrinkle efficacy.

Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Hydrolyzed Opuntia Ficus-Indica Flower Extract
Est. %0.3
Function
Origin
Hydrolyzed Opuntia Ficus-Indica Flower Extract
Biosaccharide Gum-2
Est. %0.3
Function
Origin
Biosaccharide Gum-2
Pichia Anomala Extract
Est. %0.3
Function
Origin
Pichia Anomala Extract
PVP
Est. %0.3
Function
Origin
PVPAn excellent film-former used in hairsprays, peel-off masks, and even some self-tanning products. These films are strong and hold onto the skin.
Juglans Regia (Walnut) Seed Extract
Est. %0.3
Function
Origin
Juglans Regia (Walnut) Seed Extract
Opuntia Ficus-Indica Stem Extract
Est. %0.3
Function
Origin
Opuntia Ficus-Indica Stem ExtractA soothing and antioxidant extract from prickly pear succulent stems. These stems contain a cooling and anti-inflammatory watery gel that is similar to aloe.
Vaccinium Macrocarpon (Cranberry) Fruit Extract
Est. %0.3
Function
Origin
Vaccinium Macrocarpon (Cranberry) Fruit ExtractA bright red extract derived from cranberry fruits that is rich in powerful antioxidant anthocyanins, as well as astringent tannins.
Tannic Acid
Est. %0.3
Function
Origin
Tannic Acid
Ethylhexylglycerin
Est. %0.3
Function
Origin
EthylhexylglycerinA preservative booster derived from glycerin. It is commonly paired with other preservatives to improve their efficacy. Ethylhexylglycerin is also a humectant due to its chemical base of glycerin.
Sambucus Nigra Flower Extract
Est. %0.3
Function
Origin
Sambucus Nigra Flower ExtractDerived from the plant called black elder or elderberry, this extract is an occlusive and soothing ingredient that also contains antioxidant flavonoids.
Terminalia Catappa Leaf Extract
Est. %0.3
Function
Origin
Terminalia Catappa Leaf Extract
Sodium Metabisulfite
Est. %0.3
Function
Origin
Sodium MetabisulfiteA preservative that is especially effective at preventing fungus and mold growth. It is normally combined with a strong bactericidal preservative in order to achieve broad-spectrum protection. Sodium metabisulfite is also used as an antioxidant.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Potassium Sorbate
Est. %0.3
Function
Origin
Potassium SorbateA preservative widely used in food and personal care products, available from natural sources or synthetically produced. Potassium sorbate works by inhibiting the growth of yeasts, molds, and some bacteria.
Diaminopropionoyl Tripeptide-33
Est. %0.3
Function
Origin
Diaminopropionoyl Tripeptide-33