BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 Review

BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1
1.2
/ 10
Moisturizing
2.3 Humectancy icon Humectancy
0.0 Occlusivity icon Occlusivity
2.5Anti-wrinkle icon/ 10
Anti-wrinkle
Review

Does BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 Work?

 
According to CreamScan AI's analysis of the ingredient list, here’s what BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 has to offer:
 
  • A bit of moisturizing. It has a moisturizing rating of 1.2 out of 10.
  • Modest anti-wrinkle efficacy: BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 has an anti-wrinkle rating of 2.5 out of 10 so you may expect some, although limited, effect on wrinkles.

Key Benefits of BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1

 
These are the key benefits you can expect from using BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1:
 

Slight Moisturizing When Used Alone

According to CreamScan analysis, BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 is slightly moisturizing, with a moisturizing rating of 1.2 out of 10.

Is it more humectant or occlusive? This product is purely humectant, but with a low Humectancy of 2.3 out of 10. It has zero Occlusivity as we didn't find any occlusive ingredients on the ingredient list.

This type of product provides relatively light moisturizing on its own but can contribute to overall moisturizing efficacy when used as part of a skincare routine, alongside another moisturizer.

Tip: Certain studies suggest that humectants alone may not effectively moisturize the skin. If you use this product as your only moisturizer, we recommend following it with one that contains at least some occlusive ingredients.

Please refer to the Ratings section below for details of the moisturizing rating calculation.

Modest Anti-Wrinkle Efficacy

According to CreamScan analysis, BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 has a modest level of anti-wrinkle efficacy, rated 2.5 out of 10.

It contains one ingredient with proven anti-wrinkle efficacy: Retinol (est. ≈0.1%), 
 the most effective non-prescription anti-wrinkle ingredient. Numerous clinical studies have shown its positive effects at concentrations as low as 0.1%. A study with 36 participants (Kafi et al.) confirmed that a lotion containing 0.4% retinol reduced wrinkle severity by 21% after 24 weeks of use, compared to the same formulation without retinol (vehicle).
 
Among others, BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 also contains Retinyl Palmitate, an ingredient often marketed as effective in reducing wrinkles. However, the studies supporting the anti-wrinkle claims of Retinyl Palmitate provide insufficient evidence of its efficacy according to CreamScan Research Evaluation Standards. Therefore, this ingredient does not contribute to the anti-wrinkle rating.
 
Moisturizers, when used regularly, are proven to prevent wrinkle formation and even reduce existing wrinkles. Therefore, this product, like any other moisturizer, can deliver some anti-wrinkle effects through its moisturizing action.
 

Please refer to the Ratings section below for details of the anti-wrinkle rating calculation.

Please note that this is not a complete list of benefits. We are in the process of enhancing our AI model to incorporate anti-pigmentation, exfoliation and anti-acne ratings.

Things to Be Aware Of: BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1

 
CreamScan AI identified a few things to consider before adding BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 to your skincare routine:
 

May Increase Skin Photosensitivity Due to Retinol

This product contains retinol, which offers powerful anti-wrinkle benefits. The mechanism behind retinol’s action is boosting cell turnover. This process exposes new, more delicate skin, making it more vulnerable to sun damage.

As a result, using products with retinol may increase the skin's sensitivity, making it more prone to sunburn or irritation when exposed to UV rays.

To protect the skin, dermatologists recommend applying a broad-spectrum sunscreen with at least SPF 30 throughout the duration of retinol treatment, along with avoiding direct sun exposure. Retinol should be used at night, as it is sensitive to sunlight and can lose its potency when exposed to UV rays.

Please always check the manufacturer's instructions for using the retinol-containing products, either on their website or product label.

Pros & Cons of BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1

 
Here’s an overview of the pros and cons of BeautyBio R45 The Reversal 3-Phase Retinol Booster System Phase 1 to help you decide if it’s the right choice for your skincare routine:
 

Pros:

  • Provides relatively light moisturizing on its own but can contribute to the moisturizing efficacy of any skincare routine
  • Offers modest anti-wrinkle efficacy

Cons: 

  • May increase skin photosensitivity due to retinol

Ingredients

Est. % Ingredient Origin Functions
80
6
4
3
2
1.5
0.1
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
0.3
Est. %
Water
Function:
Origin:
Safflower Glyceride
Function:
Origin:
Safflower Acid
Function:
Origin:
Lysolecithin
Function:
Origin:
Sodium Hyaluronate
Function:
Origin:
Retinyl Palmitate
Function:
Origin:
Retinol
Function:
Origin:
Glyceryl Diretinoate
Function:
Origin:
Tocopheryl Acetate
Function:
Origin:
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Function:
Origin:
Acetyl Carboxymethyl Cocoyl Glycine
Function:
Origin:
Cocoglycerides
Function:
Origin:
Caprylyl Glycol
Function:
Origin:
Polyglyceryl-10 Laurate
Function:
Origin:
Phenoxyethanol
Function:
Origin:
Citric Acid
Function:
Origin:
BHT
Function:
Origin:

Ratings

All humectants
2.3
2
0.3
Benchmark
10
All occlusives
0.0
None
Benchmark
20
Moisturizing rating
1.2
Ingredient Est. % Benchmark Raiting
Humectancy All humectants 2.3 10
2.3
2
0.3
Occlusivity All occlusives 0.0 20
0.0
None
Moisturizing rating
1.2
Ingredient Est. % Benchmark Humectancy
2
0.3
All humectants 2.3 10
2.3
All humectants
2.3
2
0.3
Benchmark
10
Ingredient Est. % Benchmark Occlusivity
None
All occlusives 0.0 20
0.0
All occlusives
0.0
None
Benchmark
20
Ingredient
Ingredient anti-wrinkle power
when present at, %
in this formula est. %
Rating
10 /10 0.4 0.1 2.5
n/a
- 1.5 -
Total
2.5
Retinol
2.5
Ingredient anti-wrinkle power
10 /10
when present at, %
0.4
in this formula, est. %
0.1
Retinyl Palmitate
-
Ingredient anti-wrinkle power
n/a
when present at, %
-
in this formula, est. %
1.5
Anti-wrinkle rating
2.5
Ingredient Est. % Benchmark
Rich in Antioxidants
2
0.3
0.3
All antioxidants 2.6 3 No
All antioxidants
2.6
Sodium Hyaluronate
2
Tocopheryl Acetate
0.3
BHT
0.3
Benchmark
3
Ingredient Est. % Benchmark
Rich in Soothing
None
All soothing 0 5 No
All soothing
0
None
Benchmark
5

Ingredients explained

Water
Est. %80
Function
Origin
WaterThe most used ingredient in skincare. Its concentration defines the product texture: rich creams may have about 50% of water while a light jelly about 90%. Water doesn’t moisturize the skin by itself and is used in skincare as a solvent for other ingredients.
Safflower Glyceride
Est. %6
Function
Origin
Safflower Glyceride
Safflower Acid
Est. %4
Function
Origin
Safflower Acid
Lysolecithin
Est. %3
Function
Origin
LysolecithinLysolecithin is a special derivative of lecithin with improved emulsifying and dispersion properties in aqueous media. This leads to a higher water-binding capacity and better skin feeling. It is usually manufactured from soy lecithin and used as an emulsifying agent.
Sodium Hyaluronate
Est. %2
Function
Origin
Sodium Hyaluronate

A sodium salt of famous hyaluronic acid. A potent humectant that hydrates the skin, supports collagen function, and fills out small wrinkles. Sodium hyaluronate also offers soothing and antioxidant properties.

Retinyl Palmitate
Est. %1.5
Function
Origin
Retinyl PalmitateAn esterified form of retinol – it combines retinol and palmitic acid into one molecule. Retinyl palmitate is less irritating than retinol but also much less effective in its anti-aging and acne-reducing effects.
Retinol
Est. %0.1
Function
Origin
Retinol

One of the most famous and well-researched anti-aging ingredients with a maximum anti-wrinkle power of 10 out of 10. It is proven to decrease wrinkles and help the skin regain its thickness, firmness, and texture. Retinol is also effective in treating pigmentation issues such as dark spots and acne.

Glyceryl Diretinoate
Est. %0.3
Function
Origin
Glyceryl Diretinoate
Tocopheryl Acetate
Est. %0.3
Function
Origin
Tocopheryl Acetate

An antioxidant derivative of tocopherol (vitamin E). It helps to protect cells from free radicals and UV damage through the conversion to active vitamin E in the skin. It is more stable than tocopherol.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Est. %0.3
Function
Origin
Acrylates/C10-30 Alkyl Acrylate CrosspolymerA synthetic ingredient that is used to thicken water and alcohol. It results in a more lightweight formula and is commonly found in gel products.
Acetyl Carboxymethyl Cocoyl Glycine
Est. %0.3
Function
Origin
Acetyl Carboxymethyl Cocoyl Glycine
Cocoglycerides
Est. %0.3
Function
Origin
CocoglyceridesA naturally-derived emollient with medium spreadability. It is oil-like and makes skin feel soft and not sticky.
Caprylyl Glycol
Est. %0.3
Function
Origin
Caprylyl GlycolAn emollient that improves product spreadability and offers a silky feel on the skin. It also acts as a preservative booster that improves the efficacy of other preservatives. According to the manufacturer, it is also a humectant moisturizer.
Polyglyceryl-10 Laurate
Est. %0.3
Function
Origin
Polyglyceryl-10 LaurateA vegetable glycerin or synthetically produced emulsifier and gentle cleansing agent. It won't leave skin feeling tight or dry when used to cleanse.
Phenoxyethanol
Est. %0.3
Function
Origin
PhenoxyethanolThe most frequently used preservative in skincare. It is a clear, oil-like liquid synthetic substance that protects products from harmful bacteria and yeast, whilst still leaving skin microflora unharmed. It is confirmed by research to be harmless.
Citric Acid
Est. %0.3
Function
Origin
Citric AcidA gently exfoliating AHA that helps to remove the top layer of dead skin cells. In comparison to other AHAs, citric acid has been shown to be one of the least effective. It is also very commonly used as a stabilizing and pH-controlling agent.
BHT
Est. %0.3
Function
Origin
BHTAn antioxidant ingredient that naturally occurs in green algae and some bacteria or fungi but, for commercial use, is created synthetically. BHT is also used occasionally as a fragrance, where it presents a sweet, camphor-like odor.